c3de1d4d2ae532cfa593833672c0eeb6  1-s2.0-S0034528824003679-main.pdf
aa13d7e3728a5d74d916b68d5a23e1fc7073660b  1-s2.0-S0034528824003679-main.pdf
cadadb711a4a39394a90b3209f4d142c528da790fdde67a2e7e4f001d9d2c7ab  1-s2.0-S0034528824003679-main.pdf

Title:           Bovine fecal biomarkers of intestinal inflammatory process: Calprotectin and lactoferrin, a comparative study
Subject:         Research in Veterinary Science, 183 (2025) 105500. doi:10.1016/j.rvsc.2024.105500
Keywords:        Biomarker,Bovine,Calprotectin,Feces,Lactoferrin,Validation
Author:          Yolanda Saco
Creator:         Elsevier
Producer:        Acrobat Distiller 8.1.0 (Windows)
CreationDate:    Thu Jan  9 17:05:27 2025 CET
ModDate:         Thu Jan  9 18:45:40 2025 CET
Custom Metadata: yes
Metadata Stream: yes
Tagged:          yes
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           3
Encrypted:       no
Page size:       595.276 x 793.701 pts
Page rot:        0
File size:       765110 bytes
Optimized:       yes
PDF version:     1.7


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
CLWGKL+TeX_CM_Maths_Symbols          Type 1C           Builtin          yes yes yes    341  0
BRWWWZ+TeX_CM_Roman                  Type 1C           Builtin          yes yes yes    345  0
OQUAGH+CharisSIL                     CID TrueType      Identity-H       yes yes yes    349  0
GBNAGF+Univers                       Type 1C           Builtin          yes yes yes    354  0
FLSEDN+STIX-Regular                  Type 1C           Custom           yes yes yes    358  0
NTMBZO+TeX_CM_Maths_Italic           Type 1C           Builtin          yes yes yes    363  0
DZKZGY+CharisSIL-Italic              CID TrueType      Identity-H       yes yes yes    367  0
WLAMVJ+CharisSIL                     CID TrueType      Identity-H       yes yes yes    335  0
WYKOGL+TimesNewRomanPSMT             CID TrueType      Identity-H       yes yes yes     65  0
OJAECF+CharisSIL-Bold                CID TrueType      Identity-H       yes yes yes     70  0
RFARJR+CharisSIL-Italic              CID TrueType      Identity-H       yes yes yes     56  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2025-03-07 02:42:46 CET
 RepresentationInformation: 1-s2.0-S0034528824003679-main.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2025-03-06 15:04:25 CET
  Size: 765110
  Format: PDF
  Version: 1.7
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF, Tagged PDF
  PDFMetadata: 
   Objects: 413
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    ViewerPreferences: 
     HideToolbar: false
     HideMenubar: false
     HideWindowUI: false
     FitWindow: false
     CenterWindow: false
     DisplayDocTitle: true
     NonFullScreenPageMode: UseNone
     Direction: L2R
     ViewArea: CropBox
     ViewClip: CropBox
     PrintArea: CropBox
     PageClip: CropBox
    PageLayout: SinglePage
    PageMode: UseOutlines
    Language: English
    Outlines: 
     Item: 
      Title: Bovine fecal biomarkers of intestinal inflammatory process: Calprotectin and lactoferrin, a comparative study
      Destination: mk:title
      Children: 
       Item: 
        Title: Study funding
        Destination: mk:H1_1
       Item: 
        Title: CRediT authorship contribution statement
        Destination: mk:H1_2
       Item: 
        Title: Declaration of competing interest
        Destination: mk:HH1_2
       Item: 
        Title: Acknowledgments
        Destination: mk:HH1_3
       Item: 
        Title: References
        Destination: mk:HH2_1
   Info: 
    Title: Bovine fecal biomarkers of intestinal inflammatory process: Calprotectin and lactoferrin, a comparative study
    Author: Yolanda Saco
    Subject: Research in Veterinary Science, 183 (2025) 105500. doi:10.1016/j.rvsc.2024.105500
    Keywords: Biomarker,Bovine,Calprotectin,Feces,Lactoferrin,Validation
    Creator: Elsevier
    Producer: Acrobat Distiller 8.1.0 (Windows)
    CreationDate: Thu Jan 09 17:05:27 CET 2025
    ModDate: Thu Jan 09 18:45:40 CET 2025
   ID: 0xd1e0171f69eb1a530890f84b9f44b43a, 0xe36f7b1e90485285591ae66f234379b0
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 236
      ImageHeight: 298
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 248
      ImageHeight: 271
      BitsPerSample: 8
      BitsPerSampleUnit: integer
   Fonts: 
    Type0: 
     Font: 
      BaseFont: WYKOGL+TimesNewRomanPSMT
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: OJAECF+CharisSIL-Bold
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: OQUAGH+CharisSIL
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: DZKZGY+CharisSIL-Italic
      Encoding: Identity-H
      ToUnicode: true
    Type1: 
     Font: 
      BaseFont: GBNAGF+Univers
      FontSubset: true
      FirstChar: 32
      LastChar: 251
      FontDescriptor: 
       FontName: GBNAGF+Univers
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: CLWGKL+TeX_CM_Maths_Symbols
      FontSubset: true
      FirstChar: 1
      LastChar: 138
      FontDescriptor: 
       FontName: CLWGKL+TeX_CM_Maths_Symbols
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: FLSEDN+STIX-Regular
      FontSubset: true
      FirstChar: 1
      LastChar: 4
      FontDescriptor: 
       FontName: FLSEDN+STIX-Regular
       Flags: Nonsymbolic
       FontBBox: -970, -486, 2208, 1023
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: BRWWWZ+TeX_CM_Roman
      FontSubset: true
      FirstChar: 1
      LastChar: 128
      FontDescriptor: 
       FontName: BRWWWZ+TeX_CM_Roman
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: NTMBZO+TeX_CM_Maths_Italic
      FontSubset: true
      FirstChar: 1
      LastChar: 127
      FontDescriptor: 
       FontName: NTMBZO+TeX_CM_Maths_Italic
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile3: true
      ToUnicode: true
    CIDFontType2: 
     Font: 
      BaseFont: DZKZGY+CharisSIL-Italic
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: DZKZGY+CharisSIL-Italic
       Flags: Nonsymbolic, Italic
       FontBBox: -716, -533, 1627, 1318
       FontFile2: true
     Font: 
      BaseFont: WYKOGL+TimesNewRomanPSMT
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: WYKOGL+TimesNewRomanPSMT
       Flags: Nonsymbolic
       FontBBox: -568, -307, 2000, 1007
       FontFile2: true
     Font: 
      BaseFont: OJAECF+CharisSIL-Bold
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: OJAECF+CharisSIL-Bold
       Flags: Nonsymbolic, ForceBold
       FontBBox: -720, -533, 1759, 1320
       FontFile2: true
     Font: 
      BaseFont: OQUAGH+CharisSIL
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: OQUAGH+CharisSIL
       Flags: Nonsymbolic
       FontBBox: -692, -533, 1623, 1319
       FontFile2: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="XMP Core 5.1.2">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>10.1016/j.rvsc.2024.105500</dc:identifier>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Elsevier Ltd</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Research in Veterinary Science, 183 (2025) 105500. doi:10.1016/j.rvsc.2024.105500</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>Biomarker</rdf:li>
               <rdf:li>Bovine</rdf:li>
               <rdf:li>Calprotectin</rdf:li>
               <rdf:li>Feces</rdf:li>
               <rdf:li>Lactoferrin</rdf:li>
               <rdf:li>Validation</rdf:li>
            </rdf:Bag>
         </dc:subject>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Bovine fecal biomarkers of intestinal inflammatory process: Calprotectin and lactoferrin, a comparative study</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Yolanda Saco</rdf:li>
               <rdf:li>Núria Crusellas-Villorbina</rdf:li>
               <rdf:li>Raquel Peña</rdf:li>
               <rdf:li>Raquel Pato</rdf:li>
               <rdf:li>Sonia Marti</rdf:li>
               <rdf:li>Lucía Pisoni</rdf:li>
               <rdf:li>Maria Devant</rdf:li>
               <rdf:li>Anna Pelegrí-Pineda</rdf:li>
               <rdf:li>Anna Bassols</rdf:li>
            </rdf:Seq>
         </dc:creator>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:prism="http://prismstandard.org/namespaces/basic/3.0/">
         <prism:aggregationType>journal</prism:aggregationType>
         <prism:publicationName>Research in Veterinary Science</prism:publicationName>
         <prism:copyright>© 2024 The Authors. Published by Elsevier Ltd.</prism:copyright>
         <prism:issn>0034-5288</prism:issn>
         <prism:volume>183</prism:volume>
         <prism:coverDisplayDate>1 February 2025</prism:coverDisplayDate>
         <prism:coverDate>2025-02-01</prism:coverDate>
         <prism:pageRange>105500</prism:pageRange>
         <prism:startingPage>105500</prism:startingPage>
         <prism:doi>10.1016/j.rvsc.2024.105500</prism:doi>
         <prism:url>https://doi.org/10.1016/j.rvsc.2024.105500</prism:url>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:crossmark="http://crossref.org/crossmark/1.0/">
         <crossmark:MajorVersionDate>2010-04-23</crossmark:MajorVersionDate>
         <crossmark:CrossmarkDomainExclusive>true</crossmark:CrossmarkDomainExclusive>
         <crossmark:DOI>10.1016/j.rvsc.2024.105500</crossmark:DOI>
         <crossmark:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>elsevier.com</rdf:li>
               <rdf:li>sciencedirect.com</rdf:li>
            </rdf:Seq>
         </crossmark:CrossMarkDomains>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:ali="http://www.niso.org/schemas/ali/1.0/">
         <ali:license_ref>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <ali:uri>http://creativecommons.org/licenses/by-nc/4.0/</ali:uri>
               </rdf:li>
            </rdf:Bag>
         </ali:license_ref>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:jav="http://www.niso.org/schemas/jav/1.0/">
         <jav:journal_article_version>VoR</jav:journal_article_version>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/">
         <HIoniy978y9aQyM2Gntz8ocNNnPv.lt-KmMaGogj.nPf-zteNm.r9o9eQndeLn9-RmMaTma/>  
         <pdfx:doi>10.1016/j.rvsc.2024.105500</pdfx:doi>
         <pdfx:robots>noindex</pdfx:robots>
         <pdfx:CrossmarkMajorVersionDate>2010-04-23</pdfx:CrossmarkMajorVersionDate>
         <pdfx:CrossmarkDomainExclusive>true</pdfx:CrossmarkDomainExclusive>
         <pdfx:CreationDate--Text>9th January 2025</pdfx:CreationDate--Text>
         <pdfx:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>sciencedirect.com</rdf:li>
               <rdf:li>elsevier.com</rdf:li>
            </rdf:Seq>
         </pdfx:CrossMarkDomains>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:CreatorTool>Elsevier</xmp:CreatorTool>
         <xmp:ModifyDate>2025-01-09T17:45:40</xmp:ModifyDate>
         <xmp:CreateDate>2025-01-09T16:05:27</xmp:CreateDate>
         <xmp:MetadataDate>2025-01-09T17:45:40</xmp:MetadataDate>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpRights="http://ns.adobe.com/xap/1.0/rights/">
         <xmpRights:Marked>True</xmpRights:Marked>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:CreationDate--Text>9th January 2025</pdf:CreationDate--Text>
         <pdf:Producer>Acrobat Distiller 8.1.0 (Windows)</pdf:Producer>
         <pdf:Keywords>Biomarker,Bovine,Calprotectin,Feces,Lactoferrin,Validation</pdf:Keywords>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <xmpMM:DocumentID>uuid:1b499bed-4ce8-4c0c-b682-0d58baae1cbe</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:b6ed5266-03cb-4855-90c0-636283357f42</xmpMM:InstanceID>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:tdm="http://www.w3.org/ns/tdmrep/">
         <tdm:reservation>1</tdm:reservation>
         <tdm:policy>https://www.elsevier.com/tdm/tdmrep-policy.json</tdm:policy>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 102, 576, 106, 587
       Flags: Print
       Destination: 323
      Annotation: 
       Subtype: Link
       Rect: 237, 576, 241, 587
       Flags: Print
       Destination: 323
      Annotation: 
       Subtype: Link
       Rect: 308, 576, 312, 587
       Flags: Print
       Destination: 323
      Annotation: 
       Subtype: Link
       Rect: 377, 576, 381, 587
       Flags: Print
       Destination: 323
      Annotation: 
       Subtype: Link
       Rect: 445, 576, 449, 587
       Flags: Print
       Destination: 323
      Annotation: 
       Subtype: Link
       Rect: 96, 563, 100, 574
       Flags: Print
       Destination: 323
      Annotation: 
       Subtype: Link
       Rect: 173, 563, 177, 574
       Flags: Print
       Destination: 323
      Annotation: 
       Subtype: Link
       Rect: 281, 563, 285, 574
       Flags: Print
       Destination: 323
      Annotation: 
       Subtype: Link
       Rect: 355, 563, 359, 574
       Flags: Print
       Destination: 323
      Annotation: 
       Subtype: Link
       Rect: 362, 563, 366, 574
       Flags: Print
       Destination: 323
      Annotation: 
       Subtype: Link
       Rect: 217, 266, 283, 274
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 250, 235, 288, 243
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 37, 224, 55, 232
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 61, 224, 132, 232
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 269, 161, 288, 169
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 37, 151, 111, 159
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 309, 308, 371, 316
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 534, 256, 557, 264
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 306, 245, 346, 253
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 351, 245, 414, 253
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 330, 203, 390, 211
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 98, 104, 167, 111
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 321, 722, 369, 730
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 279, 667, 392, 675
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 37, 87, 179, 94
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 216, 748, 378, 760
      Annotation: 
       Subtype: Link
       Rect: 499, 616, 528, 645
      Annotation: 
       Subtype: Link
       Rect: 425, 59, 557, 70
      Annotation: 
       Subtype: Link
       Rect: 37, 49, 62, 61
    Page: 
     Label: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 159, 636, 283, 644
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 130, 615, 195, 623
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 74, 437, 140, 445
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 193, 406, 213, 414
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 347, 678, 430, 686
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 320, 636, 358, 644
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 403, 573, 462, 581
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 397, 521, 419, 529
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 309, 417, 329, 425
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 309, 385, 330, 393
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 338, 375, 358, 383
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 383, 322, 452, 330
       Flags: Print
       Destination: 20
      Annotation: 
       Subtype: Link
       Rect: 435, 155, 526, 163
       Flags: Print
    Page: 
     Label: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 49, 97, 177, 103
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 502, 334, 547, 340
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 326, 376, 332
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 377, 302, 527, 308
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 470, 286, 542, 292
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 278, 348, 284
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 306, 270, 541, 276
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 262, 436, 268
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 306, 254, 549, 260
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 246, 554, 252
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 238, 405, 244
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 501, 222, 546, 228
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 214, 392, 220
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 414, 182, 546, 189
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 150, 472, 157
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 431, 126, 543, 133
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 449, 111, 521, 117
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 103, 390, 109
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 318, 79, 447, 85
       Flags: Print
  Checksum: 8239599e
   Type: CRC32
  Checksum: c3de1d4d2ae532cfa593833672c0eeb6
   Type: MD5
  Checksum: aa13d7e3728a5d74d916b68d5a23e1fc7073660b
   Type: SHA-1
  Checksum: cadadb711a4a39394a90b3209f4d142c528da790fdde67a2e7e4f001d9d2c7ab
   Type: SHA-256