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Abstract Destination: section*.2 Item: Title: 1 | INTRODUCTION Destination: section..1.1 Children: Item: Title: 1.1 | AT(N) blood-based biomarkers in adults with DS and DS-AD Destination: subsection..1.1.1 Children: Item: Title: 1.1.1 | Ab “A” biomarkers Destination: subsubsection..1.1.1.1 Item: Title: 1.1.2 | Phosphorylated tau “T” biomarkers Destination: subsubsection..1.1.1.2 Item: Title: 1.1.3 | “N” biomarkers Destination: subsubsection..1.1.1.3 Item: Title: 1.2 | Inflammatory blood-based biomarkers in DS and DS-AD Destination: subsection..1.1.2 Children: Item: Title: 1.2.1 | GFAP Destination: subsubsection..1.1.2.1 Item: Title: 1.2.2 | Pro-, anti-, and general inflammatory biomarkers Destination: subsubsection..1.1.2.2 Item: Title: 1.3 | Sex differences in DS-AD biomarkers Destination: subsection..1.1.3 Item: Title: 1.4 | Consideration for the use of AD biomarkers in studies of adults with DS Destination: subsection..1.1.4 Children: Item: Title: 1.4.1 | Longitudinal changes in AT(N) biomarkers Destination: subsubsection..1.1.4.1 Item: Title: 1.4.2 | Stability of blood biomarkers Destination: subsubsection..1.1.4.2 Item: Title: 2 | CONCLUSIONS Destination: section..1.2 Item: Title: ACKNOWLEDGMENTS Destination: section*.4 Item: Title: CONFLICT OF INTEREST STATEMENT Destination: section*.6 Item: Title: REFERENCES Destination: section*.8 Item: Title: SUPPORTING INFORMATION Destination: section*.10 Info: Title: Blood biomarkers in Down syndrome: Facilitating Alzheimer's disease detection and monitoring Author: Subject: Keywords: Creator: LaTeX with hyperref package Producer: Acrobat Distiller 10.0.0 (Windows) CreationDate: Wed Jan 29 16:16:00 CET 2025 ModDate: Wed Jan 29 16:16:28 CET 2025 ID: 0x1d3038489f164c29636400744a09e6a2, 0x83009322ded33b315176ec5202b7b64e Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: GJIBBD+Lato-Bold FontSubset: true FirstChar: 40 LastChar: 150 FontDescriptor: FontName: GJIBBD+Lato-Bold Flags: Nonsymbolic, ForceBold 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