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Destination: mk:title Children: Item: Title: 1 Introduction Destination: mk:H1_1 Item: Title: 2 Materials and methods Destination: mk:H1_2 Children: Item: Title: 2.1 Animals Destination: mk:H2_1 Item: Title: 2.2 Neonatal handling (NH) treatment Destination: mk:H2_2 Item: Title: 2.3 Novel object exploration (NOE) test Destination: mk:H2_3 Item: Title: 2.4 Social interaction (SI) test Destination: mk:H2_4 Item: Title: 2.5 Prepulse inhibition of the acoustic startle response (PPI) Destination: mk:H2_5 Item: Title: 2.6 Experimental design Destination: mk:H2_6 Item: Title: 2.7 RNA extraction and sample preparation Destination: mk:H2_7 Item: Title: 2.8 Real-time PCR Destination: mk:H2_8 Item: Title: 2.9 Statistical analysis Destination: mk:H2_9 Item: Title: 3 Results Destination: mk:H1_3 Children: Item: Title: 3.1 NOE test Destination: mk:H2_10 Item: Title: 3.2 Social Interaction (SI) test Destination: mk:H2_11 Item: Title: 3.3 Prepulse inhibition Destination: mk:H2_12 Item: Title: 3.4 Differentially expressed genes in the FC Destination: mk:H2_13 Item: Title: 3.5 Correlations among gene expression levels and between gene expression and behaviour Destination: mk:H2_14 Item: Title: 4 Discussion Destination: mk:H1_4 Children: Item: Title: 4.1 Strain differences and neonatal handling effects on behaviour as a function of age Destination: mk:H2_15 Item: Title: 4.2 Strain and neonatal handling effects on gene expression as a function of age: associations between gene expression and ... Destination: mk:H2_16 Item: Title: CRediT authorship contribution statement Destination: mk:H1_5 Item: Title: Ethical statement Destination: mk:H1_6 Item: Title: Funding Destination: mk:H1_7 Item: Title: Declaration of competing interest Destination: mk:HH1_3 Item: Title: Acknowledgements Destination: mk:HH1_4 Item: Title: Appendix A Supplementary data Destination: mk:H1_8 Item: Title: References Destination: mk:HH2_1 Info: Title: Neonatal handling enhances behavioural and attentional domains, and frontocortical synaptic maturation in rat models of schizophrenia-like behaviour and anxiety-related responses Author: Natalia Peralta-Vallejo Subject: Progress in Neuropsychopharmacology & Biological Psychiatry, 139 (2025) 111364. doi:10.1016/j.pnpbp.2025.111364 Keywords: Schizophrenia,Neonatal handling,Roman rats,Social behaviour,Prepulse inhibition,Gene expression,Frontal cortex Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Mon Apr 21 22:03:41 CEST 2025 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Progress in Neuropsychopharmacology & Biological Psychiatry, 139 (2025) 111364. doi:10.1016/j.pnpbp.2025.111364 Schizophrenia Neonatal handling Roman rats Social behaviour Prepulse inhibition Gene expression Frontal cortex Neonatal handling enhances behavioural and attentional domains, and frontocortical synaptic maturation in rat models of schizophrenia-like behaviour and anxiety-related responses Natalia Peralta-Vallejo Toni Cañete Daniel Sampedro-Viana Pau Güell-Falgueras Cristóbal Río-Álamos Ignasi Oliveras Adolf Tobeña Susana Aznar Alberto Fernández-Teruel VoR 23rd April 2025 Acrobat Distiller 8.1.0 (Windows) Schizophrenia,Neonatal handling,Roman rats,Social behaviour,Prepulse inhibition,Gene expression,Frontal cortex 23rd April 2025 10.1016/j.pnpbp.2025.111364 noindex journal © 2025 The Authors. Published by Elsevier Inc. 2025-06-20 20 June 2025 10.1016/j.pnpbp.2025.111364 0278-5846 111364 Progress in Neuropsychopharmacology & Biological Psychiatry 111364 https://doi.org/10.1016/j.pnpbp.2025.111364 139 https://www.elsevier.com/tdm/tdmrep-policy.json 1 2025-04-21T20:03:41 Elsevier 2025-04-22T19:55:44 2025-04-22T19:55:44 uuid:1b499bed-4ce8-4c0c-b682-0d58baae1cbe uuid:b6ed5266-03cb-4855-90c0-636283357f42 True Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 145, 559, 149, 569 Flags: Print Destination: 2105 Annotation: Subtype: Link Rect: 152, 559, 156, 569 Flags: Print Destination: 2105 Annotation: Subtype: Link Rect: 221, 559, 225, 569 Flags: Print Destination: 2105 Annotation: Subtype: Link Rect: 345, 559, 349, 569 Flags: Print Destination: 2105 Annotation: Subtype: Link Rect: 451, 559, 455, 569 Flags: Print Destination: 2105 Annotation: Subtype: Link Rect: 138, 546, 142, 556 Flags: Print Destination: 2105 Annotation: Subtype: Link Rect: 221, 546, 225, 556 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