beddae2ee6d57196a3beb29ab8e81485  1-s2.0-S0304389425012749-main.pdf
46a9d0e3342d57d661e4626032a4dc9b9ed5fca0  1-s2.0-S0304389425012749-main.pdf
9cee0cf7794d2457ca87a66754f789afd4384e18d5052fd623b181bad09d7f08  1-s2.0-S0304389425012749-main.pdf

Title:           The long-term in vitro co-exposure of polyethylene terephthalate (PET) nanoplastics and cigarette smoke condensate exacerbates the induction of carcinogenic traits
Subject:         Journal of Hazardous Materials, 493 (2025) 138359. doi:10.1016/j.jhazmat.2025.138359
Keywords:        Nanoplastics,Cigarette smoke condensate,Long-term co-exposure,Beas-2B cells,Carcinogenic traits
Author:          Michelle Morataya-Reyes
Creator:         Elsevier
Producer:        Acrobat Distiller 8.1.0 (Windows)
CreationDate:    Tue Apr 22 16:35:42 2025 CEST
ModDate:         Tue Apr 22 16:58:52 2025 CEST
Custom Metadata: yes
Metadata Stream: yes
Tagged:          yes
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           13
Encrypted:       no
Page size:       595.276 x 793.701 pts
Page rot:        0
File size:       5222603 bytes
Optimized:       yes
PDF version:     1.7


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
FLCRAJ+TeX_CM_Maths_Symbols          Type 1C           Builtin          yes yes yes   1473  0
LOQDMU+CharisSIL                     CID TrueType      Identity-H       yes yes yes   1477  0
OUTUKK+TeX_CM_Roman                  Type 1C           Builtin          yes yes yes   1482  0
YCHCGB+CharisSIL-Italic              CID TrueType      Identity-H       yes yes yes   1486  0
PPTTHP+CharisSIL                     CID TrueType      Identity-H       yes yes yes   1491  0
AAAKJD+CharisSIL                     CID TrueType      Identity-H       yes yes yes   1497  0
PFNGJQ+Univers                       Type 1C           Builtin          yes yes yes   1505  0
AAAAAD+CharisSIL                     CID TrueType      Identity-H       yes yes yes    359  0
ZLEPFP+STIX-Regular                  Type 1C           Custom           yes yes yes    366  0
EOGEFE+CharisSIL-Bold                CID TrueType      Identity-H       yes yes yes    371  0
GLBSAV+CharisSIL-Italic              CID TrueType      Identity-H       yes yes yes    376  0
AAAAME+CharisSIL-Italic              CID TrueType      Identity-H       yes yes yes    382  0
KIXYPY+STIX-Italic                   Type 1C           Custom           yes yes yes    389  0
VHKAOJ+TimesNewRomanPSMT             CID TrueType      Identity-H       yes yes yes    394  0
KYRRAZ+STIXGeneral                   Type 1C           Custom           yes yes yes     51  0
NTMBZO+TeX_CM_Maths_Italic           Type 1C           Builtin          yes yes yes     83  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2025-05-21 02:10:05 CEST
 RepresentationInformation: 1-s2.0-S0304389425012749-main.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2025-05-20 11:22:37 CEST
  Size: 5222603
  Format: PDF
  Version: 1.7
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF, Tagged PDF
  PDFMetadata: 
   Objects: 1601
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    ViewerPreferences: 
     HideToolbar: false
     HideMenubar: false
     HideWindowUI: false
     FitWindow: false
     CenterWindow: false
     DisplayDocTitle: true
     NonFullScreenPageMode: UseNone
     Direction: L2R
     ViewArea: CropBox
     ViewClip: CropBox
     PrintArea: CropBox
     PageClip: CropBox
    PageLayout: SinglePage
    PageMode: UseOutlines
    Language: English
    Outlines: 
     Item: 
      Title: The long-term in vitro co-exposure of polyethylene terephthalate (PET) nanoplastics and cigarette smoke condensate exacerba ...
      Destination: mk:title
      Children: 
       Item: 
        Title: 1 Introduction
        Destination: mk:H1_1
       Item: 
        Title: 2 Materials and methods
        Destination: mk:H1_2
        Children: 
         Item: 
          Title: 2.1 Particle obtention and labelling
          Destination: mk:H2_1
         Item: 
          Title: 2.2 Particle labelling
          Destination: mk:H2_2
         Item: 
          Title: 2.3 PET-NPL characterization
          Destination: mk:H2_3
          Children: 
           Item: 
            Title: 2.3.1 Scanning electron microscopy (SEM)
            Destination: mk:H3_4
           Item: 
            Title: 2.3.2 Nanotracking analysis (NTA)
            Destination: mk:H3_5
           Item: 
            Title: 2.3.3 Dynamic light scattering (DLS) and zeta potential (ζ- Pot)
            Destination: mk:H3_6
           Item: 
            Title: 2.3.4 Fourier transform infrared spectroscopy (FTIR)
            Destination: mk:H3_7
         Item: 
          Title: 2.4 Cigarette smoke condensate (CSC) preparation
          Destination: mk:H2_8
         Item: 
          Title: 2.5 Cell culture conditions
          Destination: mk:H2_9
         Item: 
          Title: 2.6 In vitro chronic PET-NPLs and CSC co-exposures
          Destination: mk:H2_10
         Item: 
          Title: 2.7 Determination of PET-NPLs internalization in BEAS-2B cells by confocal microscopy
          Destination: mk:H2_11
         Item: 
          Title: 2.8 Anchorage-independent growth induction assay (Soft-agar assay)
          Destination: mk:H2_12
         Item: 
          Title: 2.9 The comet assay
          Destination: mk:H2_13
         Item: 
          Title: 2.10 Analysis of cellular senescence
          Destination: mk:H2_14
         Item: 
          Title: 2.11 Invasion and migration induction
          Destination: mk:H2_15
         Item: 
          Title: 2.12 RNA extraction and RNA seq
          Destination: mk:H2_16
         Item: 
          Title: 2.13 Transcriptomic analysis
          Destination: mk:H2_17
         Item: 
          Title: 2.14 Relative expression of selected DEGs using real-time RT-PCR
          Destination: mk:H2_18
       Item: 
        Title: 3 Results and discussion
        Destination: mk:H1_3
        Children: 
         Item: 
          Title: 3.1 PET-NPLs characterization
          Destination: mk:H2_19
         Item: 
          Title: 3.2 PET-NPL internalization by PTP BEAS-2B cells
          Destination: mk:H2_20
         Item: 
          Title: 3.3 Genotoxic effects of PET-NPL
          Destination: mk:H2_21
         Item: 
          Title: 3.4 Anchorage-independent growth effects induced by PET-NPL
          Destination: mk:H2_22
         Item: 
          Title: 3.5 Migration and invasion effects induced by PET-NPL
          Destination: mk:H2_23
         Item: 
          Title: 3.6 Cellular senescence effects induced by PET-NPL
          Destination: mk:H2_24
         Item: 
          Title: 3.7 Transcriptomic analysis of the effects induced by PET-NPL and relative mRNA expression levels of DEGs
          Destination: mk:H2_25
       Item: 
        Title: 4 Conclusions
        Destination: mk:H1_4
       Item: 
        Title: Environmental implication
        Destination: mk:H1_5
       Item: 
        Title: CRediT authorship contribution statement
        Destination: mk:H1_6
       Item: 
        Title: Author statement
        Destination: mk:H1_7
       Item: 
        Title: Declaration of Competing Interest
        Destination: mk:HH1_3
       Item: 
        Title: Acknowledgments
        Destination: mk:HH1_4
       Item: 
        Title: Data availability
        Destination: datalink5
       Item: 
        Title: References
        Destination: mk:HH2_1
   Info: 
    Title: The long-term in vitro co-exposure of polyethylene terephthalate (PET) nanoplastics and cigarette smoke condensate exacerbates the induction of carcinogenic traits
    Author: Michelle Morataya-Reyes
    Subject: Journal of Hazardous Materials, 493 (2025) 138359. doi:10.1016/j.jhazmat.2025.138359
    Keywords: Nanoplastics,Cigarette smoke condensate,Long-term co-exposure,Beas-2B cells,Carcinogenic traits
    Creator: Elsevier
    Producer: Acrobat Distiller 8.1.0 (Windows)
    CreationDate: Tue Apr 22 16:35:42 CEST 2025
    ModDate: Tue Apr 22 16:58:52 CEST 2025
   ID: 0x14a766b8fbd2af96d91a9ed91d40bca2, 0x735a7e248a777da32334aed7063a3d69
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 248
      ImageHeight: 271
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 236
      ImageHeight: 298
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 33
      ImageHeight: 33
      BitsPerSample: 8
      BitsPerSampleUnit: integer
   Fonts: 
    Type0: 
     Font: 
      BaseFont: PPTTHP+CharisSIL
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: EOGEFE+CharisSIL-Bold
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: LOQDMU+CharisSIL
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: AAAAAD+CharisSIL
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: GLBSAV+CharisSIL-Italic
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: AAAKJD+CharisSIL
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: VHKAOJ+TimesNewRomanPSMT
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: YCHCGB+CharisSIL-Italic
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: AAAAME+CharisSIL-Italic
      Encoding: Identity-H
      ToUnicode: true
    Type1: 
     Font: 
      BaseFont: FLCRAJ+TeX_CM_Maths_Symbols
      FontSubset: true
      FirstChar: 1
      LastChar: 138
      FontDescriptor: 
       FontName: FLCRAJ+TeX_CM_Maths_Symbols
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: PFNGJQ+Univers
      FontSubset: true
      FirstChar: 32
      LastChar: 251
      FontDescriptor: 
       FontName: PFNGJQ+Univers
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: KYRRAZ+STIXGeneral
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: KYRRAZ+STIXGeneral
       Flags: Nonsymbolic
       FontBBox: -178, -443, 2000, 1023
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: NTMBZO+TeX_CM_Maths_Italic
      FontSubset: true
      FirstChar: 1
      LastChar: 127
      FontDescriptor: 
       FontName: NTMBZO+TeX_CM_Maths_Italic
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: KIXYPY+STIX-Italic
      FontSubset: true
      FirstChar: 1
      LastChar: 2
      FontDescriptor: 
       FontName: KIXYPY+STIX-Italic
       Flags: Nonsymbolic, Italic
       FontBBox: -970, -305, 1429, 1023
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: OUTUKK+TeX_CM_Roman
      FontSubset: true
      FirstChar: 1
      LastChar: 128
      FontDescriptor: 
       FontName: OUTUKK+TeX_CM_Roman
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile3: true
      ToUnicode: true
     Font: 
      BaseFont: ZLEPFP+STIX-Regular
      FontSubset: true
      FirstChar: 1
      LastChar: 13
      FontDescriptor: 
       FontName: ZLEPFP+STIX-Regular
       Flags: Nonsymbolic
       FontBBox: -970, -486, 2208, 1023
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
    CIDFontType2: 
     Font: 
      BaseFont: YCHCGB+CharisSIL-Italic
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: YCHCGB+CharisSIL-Italic
       Flags: Nonsymbolic, Italic
       FontBBox: -716, -533, 1627, 1318
       FontFile2: true
     Font: 
      BaseFont: AAAAME+CharisSIL-Italic
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: AAAAME+CharisSIL-Italic
       Flags: Symbolic, Italic
       FontBBox: -716, -533, 1626, 1317
       FontFile2: true
     Font: 
      BaseFont: PPTTHP+CharisSIL
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: PPTTHP+CharisSIL
       Flags: Serif, Symbolic
       FontBBox: -692, -533, 1623, 1319
       FontFile2: true
     Font: 
      BaseFont: EOGEFE+CharisSIL-Bold
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: EOGEFE+CharisSIL-Bold
       Flags: Nonsymbolic, ForceBold
       FontBBox: -720, -533, 1759, 1320
       FontFile2: true
     Font: 
      BaseFont: LOQDMU+CharisSIL
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: LOQDMU+CharisSIL
       Flags: Nonsymbolic
       FontBBox: -692, -533, 1623, 1319
       FontFile2: true
     Font: 
      BaseFont: AAAAAD+CharisSIL
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: AAAAAD+CharisSIL
       Flags: Symbolic
       FontBBox: -692, -533, 1623, 1318
       FontFile2: true
     Font: 
      BaseFont: GLBSAV+CharisSIL-Italic
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: GLBSAV+CharisSIL-Italic
       Flags: Serif, Symbolic, Italic
       FontBBox: -716, -533, 1627, 1318
       FontFile2: true
     Font: 
      BaseFont: AAAKJD+CharisSIL
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: AAAKJD+CharisSIL
       Flags: Symbolic
       FontBBox: -692, -533, 1623, 1318
       FontFile2: true
     Font: 
      BaseFont: VHKAOJ+TimesNewRomanPSMT
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: VHKAOJ+TimesNewRomanPSMT
       Flags: Nonsymbolic
       FontBBox: -568, -307, 2000, 1007
       FontFile2: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="XMP Core 5.1.2">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:ali="http://www.niso.org/schemas/ali/1.0/">
         <ali:license_ref>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <ali:uri>http://creativecommons.org/licenses/by/4.0/</ali:uri>
               </rdf:li>
            </rdf:Bag>
         </ali:license_ref>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>10.1016/j.jhazmat.2025.138359</dc:identifier>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Elsevier B.V.</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Journal of Hazardous Materials, 493 (2025) 138359. doi:10.1016/j.jhazmat.2025.138359</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>Nanoplastics</rdf:li>
               <rdf:li>Cigarette smoke condensate</rdf:li>
               <rdf:li>Long-term co-exposure</rdf:li>
               <rdf:li>Beas-2B cells</rdf:li>
               <rdf:li>Carcinogenic traits</rdf:li>
            </rdf:Bag>
         </dc:subject>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">The long-term in vitro co-exposure of polyethylene terephthalate (PET) nanoplastics and cigarette smoke condensate exacerbates the induction of carcinogenic traits</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Michelle Morataya-Reyes</rdf:li>
               <rdf:li>Aliro Villacorta</rdf:li>
               <rdf:li>Javier Gutiérrez-García</rdf:li>
               <rdf:li>Raquel Egea</rdf:li>
               <rdf:li>Joan Martín-Pérez</rdf:li>
               <rdf:li>Irene Barguilla</rdf:li>
               <rdf:li>Ricard Marcos</rdf:li>
               <rdf:li>Alba Hernández</rdf:li>
            </rdf:Seq>
         </dc:creator>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:jav="http://www.niso.org/schemas/jav/1.0/">
         <jav:journal_article_version>VoR</jav:journal_article_version>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:CreationDate--Text>22nd April 2025</pdf:CreationDate--Text>
         <pdf:Producer>Acrobat Distiller 8.1.0 (Windows)</pdf:Producer>
         <pdf:Keywords>Nanoplastics,Cigarette smoke condensate,Long-term co-exposure,Beas-2B cells,Carcinogenic traits</pdf:Keywords>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/">
         <pdfx:CreationDate--Text>22nd April 2025</pdfx:CreationDate--Text>
         <X9O3Cy9b-mdb-mPiGy.yJmsNNotf9lt6QyPeGzwr8m.r_z.uOm9-No9eQnd2QmMiSnduTma/>  
         <pdfx:doi>10.1016/j.jhazmat.2025.138359</pdfx:doi>
         <pdfx:robots>noindex</pdfx:robots>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:prism="http://prismstandard.org/namespaces/basic/3.0/">
         <prism:aggregationType>journal</prism:aggregationType>
         <prism:copyright>© 2025 The Authors. Published by Elsevier B.V.</prism:copyright>
         <prism:coverDate>2025-08-05</prism:coverDate>
         <prism:coverDisplayDate>5 August 2025</prism:coverDisplayDate>
         <prism:doi>10.1016/j.jhazmat.2025.138359</prism:doi>
         <prism:issn>0304-3894</prism:issn>
         <prism:pageRange>138359</prism:pageRange>
         <prism:publicationName>Journal of Hazardous Materials</prism:publicationName>
         <prism:startingPage>138359</prism:startingPage>
         <prism:url>https://doi.org/10.1016/j.jhazmat.2025.138359</prism:url>
         <prism:volume>493</prism:volume>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:tdm="http://www.w3.org/ns/tdmrep/">
         <tdm:policy>https://www.elsevier.com/tdm/tdmrep-policy.json</tdm:policy>
         <tdm:reservation>1</tdm:reservation>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:CreateDate>2025-04-22T14:35:42</xmp:CreateDate>
         <xmp:CreatorTool>Elsevier</xmp:CreatorTool>
         <xmp:MetadataDate>2025-04-22T14:58:52</xmp:MetadataDate>
         <xmp:ModifyDate>2025-04-22T14:58:52</xmp:ModifyDate>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <xmpMM:DocumentID>uuid:1b499bed-4ce8-4c0c-b682-0d58baae1cbe</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:b6ed5266-03cb-4855-90c0-636283357f42</xmpMM:InstanceID>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpRights="http://ns.adobe.com/xap/1.0/rights/">
         <xmpRights:Marked>True</xmpRights:Marked>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 157, 559, 161, 569
       Flags: Print
       Destination: 1465
      Annotation: 
       Subtype: Link
       Rect: 162, 557, 170, 565
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 162, 554, 170, 565
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 251, 559, 255, 569
       Flags: Print
       Destination: 1465
      Annotation: 
       Subtype: Link
       Rect: 257, 559, 262, 569
       Flags: Print
       Destination: 1465
      Annotation: 
       Subtype: Link
       Rect: 262, 557, 271, 565
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 262, 554, 271, 565
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 388, 559, 392, 569
       Flags: Print
       Destination: 1465
      Annotation: 
       Subtype: Link
       Rect: 393, 557, 401, 565
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 393, 554, 401, 565
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 468, 559, 472, 569
       Flags: Print
       Destination: 1465
      Annotation: 
       Subtype: Link
       Rect: 472, 557, 480, 565
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 472, 554, 480, 565
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 125, 546, 129, 556
       Flags: Print
       Destination: 1465
      Annotation: 
       Subtype: Link
       Rect: 129, 544, 138, 552
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 129, 541, 138, 552
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 216, 546, 220, 556
       Flags: Print
       Destination: 1465
      Annotation: 
       Subtype: Link
       Rect: 220, 544, 229, 552
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 220, 541, 229, 552
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 305, 546, 309, 556
       Flags: Print
       Destination: 1465
      Annotation: 
       Subtype: Link
       Rect: 311, 546, 315, 556
       Flags: Print
       Destination: 1465
      Annotation: 
       Subtype: Link
       Rect: 316, 544, 324, 552
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 316, 541, 324, 552
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 408, 546, 412, 556
       Flags: Print
       Destination: 1465
      Annotation: 
       Subtype: Link
       Rect: 414, 546, 418, 556
       Flags: Print
       Destination: 1465
      Annotation: 
       Subtype: Link
       Rect: 103, 104, 177, 111
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 221, 104, 299, 111
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 321, 722, 369, 730
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 272, 667, 399, 675
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 37, 87, 192, 94
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 215, 748, 379, 760
      Annotation: 
       Subtype: Link
       Rect: 406, 57, 552, 69
    Page: 
     Label: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 184, 577, 200, 585
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 259, 546, 286, 554
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 37, 368, 53, 376
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 126, 326, 142, 334
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 220, 316, 235, 324
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 179, 295, 206, 303
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 222, 285, 238, 292
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 191, 201, 202, 209
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 37, 149, 48, 157
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 541, 651, 557, 659
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 345, 504, 360, 512
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 306, 452, 322, 460
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 479, 410, 494, 418
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 400, 400, 416, 408
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 474, 358, 490, 366
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 468, 337, 483, 345
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 361, 211, 377, 219
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 404, 201, 415, 209
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 361, 149, 376, 157
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 446, 107, 461, 115
       Flags: Print
       Destination: 152
    Page: 
     Label: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 37, 678, 53, 686
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 37, 500, 53, 508
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 219, 448, 234, 456
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 452, 245, 464, 253
       Flags: Print
       Destination: 152
    Page: 
     Label: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 259, 689, 275, 696
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 270, 301, 286, 309
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 341, 311, 367, 319
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 338, 301, 353, 309
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 359, 269, 382, 277
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 464, 238, 487, 246
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 514, 228, 530, 236
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 526, 217, 542, 225
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 328, 207, 344, 215
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 431, 175, 447, 183
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 348, 133, 364, 141
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 406, 81, 444, 89
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 324, 50, 351, 58
       Flags: Print
       Destination: 273
    Page: 
     Label: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 399, 584, 419, 592
       Flags: Print
       Destination: 47
      Annotation: 
       Subtype: Link
       Rect: 485, 486, 505, 494
       Flags: Print
       Destination: 62
      Annotation: 
       Subtype: Link
       Rect: 472, 475, 493, 483
       Flags: Print
       Destination: 62
      Annotation: 
       Subtype: Link
       Rect: 383, 465, 405, 473
       Flags: Print
       Destination: 62
      Annotation: 
       Subtype: Link
       Rect: 491, 455, 512, 462
       Flags: Print
       Destination: 62
      Annotation: 
       Subtype: Link
       Rect: 437, 444, 458, 452
       Flags: Print
       Destination: 62
    Page: 
     Label: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 185, 535, 201, 543
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 231, 482, 242, 490
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 117, 472, 132, 480
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 227, 430, 243, 438
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 156, 315, 183, 323
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 506, 514, 517, 522
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 446, 482, 466, 490
       Flags: Print
       Destination: 62
      Annotation: 
       Subtype: Link
       Rect: 419, 441, 435, 448
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 495, 420, 506, 428
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 365, 399, 377, 407
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 420, 325, 436, 333
       Flags: Print
       Destination: 152
    Page: 
     Label: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 76, 720, 92, 728
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 96, 720, 116, 728
       Flags: Print
       Destination: 79
      Annotation: 
       Subtype: Link
       Rect: 243, 699, 263, 707
       Flags: Print
       Destination: 79
      Annotation: 
       Subtype: Link
       Rect: 223, 668, 243, 676
       Flags: Print
       Destination: 79
      Annotation: 
       Subtype: Link
       Rect: 84, 636, 100, 644
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 103, 636, 114, 644
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 274, 626, 288, 634
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 37, 615, 45, 623
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 74, 605, 86, 613
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 37, 584, 53, 592
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 116, 485, 127, 493
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 240, 443, 261, 451
       Flags: Print
       Destination: 110
      Annotation: 
       Subtype: Link
       Rect: 107, 360, 118, 368
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 102, 276, 118, 284
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 422, 720, 437, 728
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 440, 720, 456, 728
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 449, 636, 465, 644
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 458, 594, 473, 602
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 351, 527, 370, 535
       Flags: Print
       Destination: 110
      Annotation: 
       Subtype: Link
       Rect: 388, 443, 404, 451
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 522, 381, 538, 389
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 306, 339, 329, 347
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 397, 245, 412, 253
       Flags: Print
       Destination: 152
    Page: 
     Label: 8
    Page: 
     Label: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 181, 615, 197, 623
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 122, 573, 145, 581
       Flags: Print
       Destination: 110
      Annotation: 
       Subtype: Link
       Rect: 37, 479, 53, 487
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 37, 448, 53, 456
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 187, 427, 203, 435
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 37, 364, 53, 372
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 196, 343, 211, 351
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 185, 312, 201, 320
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 241, 281, 257, 289
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 235, 249, 251, 257
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 60, 145, 76, 153
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 220, 134, 235, 142
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 146, 82, 166, 90
       Flags: Print
       Destination: 110
      Annotation: 
       Subtype: Link
       Rect: 525, 689, 545, 696
       Flags: Print
       Destination: 141
      Annotation: 
       Subtype: Link
       Rect: 349, 615, 368, 623
       Flags: Print
       Destination: 148
      Annotation: 
       Subtype: Link
       Rect: 528, 479, 555, 487
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 461, 417, 477, 425
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 512, 343, 528, 351
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 404, 302, 420, 309
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 367, 239, 383, 247
       Flags: Print
       Destination: 152
    Page: 
     Label: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 56, 94, 72, 102
       Flags: Print
       Destination: 273
      Annotation: 
       Subtype: Link
       Rect: 440, 282, 451, 290
       Flags: Print
       Destination: 152
      Annotation: 
       Subtype: Link
       Rect: 539, 241, 555, 248
       Flags: Print
       Destination: 152
    Page: 
     Label: 11
    Page: 
     Label: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 223, 696, 269, 703
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 53, 688, 135, 695
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 253, 665, 286, 671
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 53, 657, 138, 663
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 241, 633, 286, 639
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 53, 625, 146, 631
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 207, 601, 279, 607
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 53, 593, 94, 599
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 214, 561, 286, 567
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 53, 553, 99, 559
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 53, 521, 180, 527
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 141, 505, 282, 512
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 53, 497, 71, 504
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 208, 473, 280, 480
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 53, 465, 109, 472
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 53, 433, 184, 440
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 122, 402, 243, 408
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 202, 386, 274, 392
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 378, 112, 384
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 136, 354, 252, 360
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 223, 338, 268, 344
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 330, 163, 336
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 100, 314, 237, 320
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 146, 282, 261, 288
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 79, 250, 217, 257
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 97, 226, 239, 233
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 173, 210, 249, 217
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 202, 97, 209
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 164, 178, 281, 185
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 224, 162, 270, 169
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 154, 143, 161
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 183, 123, 259, 129
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 115, 131, 121
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 264, 91, 286, 97
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 83, 162, 89
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 198, 59, 270, 65
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 51, 105, 57
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 481, 700, 553, 706
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 692, 368, 698
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 404, 668, 544, 674
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 636, 423, 643
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 604, 433, 611
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 596, 555, 603
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 588, 451, 595
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 491, 572, 537, 579
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 565, 390, 571
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 389, 533, 497, 539
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 470, 509, 542, 515
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 501, 378, 507
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 376, 477, 513, 483
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 533, 461, 555, 467
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 453, 422, 459
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 454, 429, 530, 435
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 421, 388, 427
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 504, 405, 550, 411
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 397, 396, 403
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 471, 381, 555, 388
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 373, 345, 380
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 396, 373, 512, 380
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 380, 349, 508, 356
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 401, 325, 505, 332
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 522, 301, 555, 308
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 294, 406, 300
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 358, 254, 480, 260
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 439, 230, 552, 236
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 457, 198, 533, 204
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 190, 380, 196
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 533, 158, 555, 164
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 150, 413, 156
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 126, 427, 133
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 521, 94, 554, 101
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 86, 431, 93
       Flags: Print
    Page: 
     Label: 13
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 222, 732, 268, 738
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 724, 119, 730
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 700, 184, 706
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 676, 138, 682
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 261, 652, 284, 658
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 644, 165, 651
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 166, 620, 271, 627
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 174, 596, 277, 603
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 588, 68, 595
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 111, 565, 237, 571
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 94, 541, 234, 547
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 232, 509, 277, 515
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 501, 139, 507
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 147, 461, 258, 467
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 170, 445, 242, 451
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 437, 103, 443
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 225, 405, 270, 411
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 397, 142, 403
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 145, 381, 211, 388
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 253, 365, 286, 372
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 357, 133, 364
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 231, 325, 276, 332
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 54, 317, 148, 324
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 436, 700, 512, 706
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 692, 385, 698
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 684, 539, 690
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 676, 555, 682
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 668, 555, 674
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 660, 460, 666
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 348, 628, 488, 635
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 491, 604, 555, 611
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 596, 384, 603
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 588, 533, 595
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 580, 531, 587
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 572, 554, 579
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 565, 351, 571
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 367, 549, 505, 555
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 522, 533, 555, 539
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 525, 420, 531
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 427, 501, 550, 507
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 493, 547, 499
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 485, 540, 491
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 477, 523, 483
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 407, 453, 528, 459
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 392, 421, 497, 427
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 348, 389, 447, 396
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 498, 373, 544, 380
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 365, 401, 372
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 510, 349, 555, 356
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 323, 341, 386, 348
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 348, 317, 483, 324
       Flags: Print
  Checksum: 28b0c4a1
   Type: CRC32
  Checksum: beddae2ee6d57196a3beb29ab8e81485
   Type: MD5
  Checksum: 46a9d0e3342d57d661e4626032a4dc9b9ed5fca0
   Type: SHA-1
  Checksum: 9cee0cf7794d2457ca87a66754f789afd4384e18d5052fd623b181bad09d7f08
   Type: SHA-256