190567e31e074a3f4f87babd647a8e9b OSSSI_RectalSurgery_BJS.pdf d8493c5de8ab843042abc293e5213d66ea15d767 OSSSI_RectalSurgery_BJS.pdf e44464df5feccb8a1693360718b925cdf5c164606d076440cc099fdf74c9012d OSSSI_RectalSurgery_BJS.pdf Title: Organ/space surgical site infection and long-term outcomes of rectal cancer surgery: retrospective population-based cohort study Subject: DOI: 10.1093/bjsopen/zraf052; BJS Open, 9, 3, 2025-06-12.; Abstract: Background: Anastomotic leak and subsequent organ/space surgical site infection (O/S-SSI) after colorectal cancer surgery are associated with poor short-term outcomes; however, the evidence regarding long-term outcomes is inconclusive. This population-based retrospective cohort study aimed to evaluate the association between O/S-SSI and both tumour recurrence and long-term survival after curative rectal cancer surgery. Methods: Data was obtained for all adults who underwent curative oncological resection of the rectum in the periods 2011–2012 and 2015–2016 (n = 2208) in Spain. Multivariable analysis (Cox proportional hazards model) was used to evaluate the effects of clinical and pathological characteristics, as well as the occurrence of O/S-SSI, on recurrence and survival. Results: In all, 2208 adults underwent curative rectal cancer resection, 1464 of whom were male (66.3%); the median patient age was 69.1 years. 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10.1093/bjsopen/zraf052 en Oxford University Press Organ/space surgical site infection and long-term outcomes of rectal cancer surgery: retrospective population-based cohort study Carlota Matallana Paula Manchon-Walsh Eloy Espín Marta Pascual Sebastiano Biondo Marta Jiménez-Toscano Josep Maria Borràs Josep M. Badia Enric Limón Luisa Aliste Rebeca Font Miguel Pera DOI: 10.1093/bjsopen/zraf052; BJS Open, 9, 3, 2025-06-12.; Abstract: Background: Anastomotic leak and subsequent organ/space surgical site infection (O/S-SSI) after colorectal cancer surgery are associated with poor short-term outcomes; however, the evidence regarding long-term outcomes is inconclusive. This population-based retrospective cohort study aimed to evaluate the association between O/S-SSI and both tumour recurrence and long-term survival after curative rectal cancer surgery. Methods: Data was obtained for all adults who underwent curative oncological resection of the rectum in the periods 2011–2012 and 2015–2016 (n = 2208) in Spain. Multivariable analysis (Cox proportional hazards model) was used to evaluate the effects of clinical and pathological characteristics, as well as the occurrence of O/S-SSI, on recurrence and survival. Results: In all, 2208 adults underwent curative rectal cancer resection, 1464 of whom were male (66.3%); the median patient age was 69.1 years. © The Author(s) 2025. Published by Oxford University Press on behalf of BJS Foundation Ltd. Journal BJS Open © The Author(s) 2025. Published by Oxford University Press on behalf of BJS Foundation Ltd. 2474-9842 9 3 1 10 10.1093/bjsopen/zraf052 https://doi.org/10.1093/bjsopen/zraf052 2025-06-11T13:11:55+05:30 2025-06-16T14:55:48+02:00 Servigistics Arbortext Advanced Print Publisher 11.1.4546/W-x64 2025-06-16T14:55:48+02:00 PStill version 1.84.42 1 PDF/UA Universal Accessibility Schema http://www.aiim.org/pdfua/ns/id/ pdfuaid part Integer internal Indicates, which part of ISO 14289 standard is followed Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 116, 586, 119, 594 Flags: Print Destination: 1986 Annotation: Subtype: Link Rect: 121, 586, 124, 594 Flags: Print Destination: 1986 Annotation: Subtype: Link Rect: 126, 586, 129, 594 Flags: Print Destination: 1986 Annotation: Subtype: Link Rect: 220, 586, 223, 594 Flags: Print Destination: 1986 Annotation: Subtype: Link Rect: 225, 586, 228, 594 Flags: Print Destination: 1986 Annotation: Subtype: Link Rect: 230, 582, 240, 592 Flags: Print Annotation: 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