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Title:           Systematic review and evidence-based classification of differentially expressed mRNA in human spermatozoa: insights to improve the diagnosis and prognosis of male infertility
Subject:         Reproductive BioMedicine Online, 51 (2025) 104993. doi:10.1016/j.rbmo.2025.104993
Keywords:        "Assisted reproductive technology"; "Biomarker"; "Gene prioritization"; "Male infertility"; "Sperm mRNA"
Author:          Ester Anton
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      Title: Systematic review and evidence-based classification of differentially expressed mRNA in human spermatozoa: insights to improve the diagnosis and prognosis of male infertility
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      Children: 
       Item: 
        Title: INTRODUCTION
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       Item: 
        Title: MATERIALS AND METHODS
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        Children: 
         Item: 
          Title: Registration
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         Item: 
          Title: Search strategy
          Destination: Head5
         Item: 
          Title: Study selection
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         Item: 
          Title: Data extraction
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         Item: 
          Title: Gene scoring
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       Item: 
        Title: RESULTS
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         Item: 
          Title: Search strategy and study selection
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         Item: 
          Title: Data extraction and analysis
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          Children: 
           Item: 
            Title: Primary objective analysis
            Destination: Head12
           Item: 
            Title: Methodological evaluation
            Destination: Head13
         Item: 
          Title: Genes and male infertility
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          Children: 
           Item: 
            Title: Overview of the biological functions associated with genes in the top bins (Bins 8, 9 and 10)
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           Item: 
            Title: Association between altered gene expression and seminal parameters
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           Item: 
            Title: Association between altered gene expression and ART outcome
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           Item: 
            Title: Association between altered gene expression and varicocele
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           Item: 
            Title: Association between altered gene expression and substance users
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        Title: DISCUSSION
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         Item: 
          Title: Methodological considerations
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         Item: 
          Title: Scoring system reliability
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         Item: 
          Title: Cause or consequence?
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         Item: 
          Title: What is next?
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       Item: 
        Title: CONCLUSIONS
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         Item: 
          Title: Acknowledgements
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         Item: 
          Title: Author contributions
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         Item: 
          Title: Declaration of generative AI and AI-assisted technologies in the writing process
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       Item: 
        Title: Supplementary materials
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        Children: 
         Item: 
          Title: REFERENCES
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   Type: CRC32
  Checksum: 47fb3641b2822d37c382e869362a99c2
   Type: MD5
  Checksum: cb487aabf681594a8f8572362eed1d3ecadf845b
   Type: SHA-1
  Checksum: 764581e7bc81dbac4ca8c443a853ee9b8c2e42d2743e7a1004d6c66440c7f860
   Type: SHA-256