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Destination: titlink1 Children: Item: Title: Introduction Destination: flink1 Item: Title: Methods Destination: flink2 Children: Item: Title: Study design Destination: slink1 Item: Title: Patient selection and study sites Destination: slink2 Item: Title: Ethics and privacy Destination: slink3 Item: Title: Data collection Destination: slink4 Item: Title: Intervention Destination: slink5 Item: Title: FLR volumetry Destination: slink6 Item: Title: Liver resection Destination: slink7 Item: Title: Primary outcome Destination: slink8 Item: Title: Secondary outcomes Destination: slink9 Children: Item: Title: PVE/HVE technique Destination: thirlink1 Item: Title: Recruitment capacity Destination: thirlink2 Item: Title: Safety Destination: thirlink3 Item: Title: Resectability Destination: thirlink4 Item: Title: Oncological outcomes Destination: thirlink5 Item: Title: Protocol deviations Destination: slink10 Item: Title: Statistics Destination: slink11 Item: Title: Funding Destination: slink12 Item: Title: Results Destination: flink3 Children: Item: Title: Patients Destination: slink13 Item: Title: Primary outcome Destination: slink14 Item: Title: Secondary outcomes Destination: slink15 Children: Item: Title: PVE/HVE technique Destination: thirlink6 Item: Title: Recruitment capacity Destination: thirlink7 Item: Title: Safety of PVE/HVE Destination: thirlink8 Item: Title: Safety of resection Destination: thirlink9 Item: Title: FLR volume changes Destination: thirlink10 Item: Title: Clinical resectability Destination: thirlink11 Item: Title: Radiological resectability Destination: thirlink12 Item: Title: Discussion Destination: flink4 Item: Title: ContributorsAll authors contributed to the study design, data collection, and writing—review & editing. Specific contributi ... Destination: blink1 Item: Title: Data sharing statementR. Korenblik, S. James, J. Smits, C. van der Leij, M. Dewulf, and R.M. van Dam had full access to all ... Destination: blink2 Item: Title: Declaration of interests Destination: blink3 Item: Title: Acknowledgements Destination: blink4 Item: Title: Appendix A. 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Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1016/j.lanepe.2025.101284 Safety and efficacy of combined portal and hepatic vein embolisation in patients with colorectal liver metastases (DRAGON1): a multicentre, single-arm clinical trial Remon Korenblik Sinéad James Jens Smits Rafael Díaz-Nieto Rob Davis Benjamin K.Y. Chan Joris I. Erdmann IJsbrand A.J. Zijlstra Pieter J.W. Arntz Otto Kollmar Martin H. Hoffmann David G. Vass Richard Lindsay Matteo Serenari Alberto Cappelli Paul D. Gobardhan Farshad Imani Yiliam Fundora Suarez Fernando Gómez Muños Dirk J. Grünhagen Adriaan Moelker Kay J. Pieterman Jörg Kleeff Walter A. Wohlgemuth Eric Herrero Arantxa Gelabert Stefan Breitenstein Nico Seeger Olivier Detry Laurent Gerard Per A. Sandström Bergthor Björnsson Luca A. Aldrighetti Francesco De Cobelli Wouter K.G. Leclercq Laurens J. van Baardewijk Daniel Croagh Diederick W. De Boo T. Peter Kingham Fourat Ridouani Peter Metrakos David Valenti Jennifer Kalil Åsmund A. Fretland Ulrik Carling Guillaume Martel Stephen Ryan Venkatesha Udupa Andrew Macdonald Jordan C. Tasse Gregor A. Stavrou Elmar Spuentrup Francisco G. Borobia Eva Criado Ernesto Sparrelid Martin Delle Jordi Navinés-López Jaume Sampere Moragues Esteban Cugat Andorrà Andreas Schnitzbauer Thomas J. Vogl Jan Heil John N. Primrose Sachin Modi Suomi M.G. Fouraschen Reinoud P.H. Bokkers Marieke T. de Boer Inne H.M. Borel Rinkes Maarten L.J. Smits Thomas Gruenberger Ivan Baclija Kevin G. Billingsley David C. Madoff Alejandro Serrablo Luis Sarriá Xiaoying Wang Qu Xudong Bjorn Winkens Steven W.L. Olde Damink Marc H.A. Bemelmans Maxime J.L. Dewulf Christoph A. Binkert Erik Schadde Christiaan van der Leij Ronald M. van Dam DRAGON collaborative study group M. Abu Hilal C. Aloman K. Brousseau R.C.G. Bruijnen M. Cescon B. Chand J. Codina Font M. Crawford S.W. de Boer J.F. De Wispelaere A. Dili M. Dixon J. Engstrand A. Erbahceci Salik S.W. Fenwick O. Fisher S. Gilg F. Giuliante L.F. Grochola J. Hagendoorn M.H. Heijmans G.F. Hess R. Iezzi R. Jones G. Kazemier S. Kern R.R.M.M. Knapen C. Lambrecht S. Lopez-Ben V. Lucidi D. Maclean H. Malik G. Maleux M.R. Meijerink J. Melenhorst K. Menon D. Murphy B. Olij J.E. Oor S. Pappas P. Peddu F. Ratti M. Ravaioli C. Rogan U. Ronellenfitsch S. Ross C. Sallemi L.A. Sahan R.J. Swijnenburg I. Tancredi O.M. Van Delden A.L. van der Velden M. Vandermeulen R. Widyaningsih R. Young Portal vein embolization Hepatic vein embolization Liver venous deprivation Colorectal liver metastases Future liver remnant Liver resection FLR hypertrophy Kinetic growth rate Post-hepatectomy liver failure Liver surgery complications Hepatic regeneration Multicenter clinical trial Resection rates Embolization techniques Extended liver resection Regenerative liver procedures DRAGON 1 trial Preoperative liver augmentation Surgical oncology Bilobar colorectal liver metastases The Lancet Regional Health - Europe, 53 (2025) 101284. doi:10.1016/j.lanepe.2025.101284 Elsevier Ltd journal The Lancet Regional Health - Europe © 2025 Published by Elsevier Ltd. 2666-7762 53 June 2025 101284 101284 10.1016/j.lanepe.2025.101284 https://doi.org/10.1016/j.lanepe.2025.101284 2010-04-23 true 10.1016/j.lanepe.2025.101284 elsevier.com sciencedirect.com VoR 7.0.1 10.1016/j.lanepe.2025.101284 noindex 2010-04-23 true sciencedirect.com elsevier.com Elsevier 2025-05-29T09:54:20+05:30 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