743776e8fd48a8c5d321f0f14d66565a 319533.pdf d5dac3e60434b77366d6e1d9edf323a1d9496fde 319533.pdf d6717fe77e8d6d32c9dc175776894f07e9c95e2a3d06bb90c5598157288fc7e5 319533.pdf Title: Hemodynamic profile of terlipressin and octreotide in patients with cirrhosis and portal hypertension: a randomized, single-blind clinical trial Subject: Journal of Hepatology, 7 (2025) 101325. doi:10.1016/j.jhepr.2024.101325 Author: Valeria Perez-Campuzano Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Tue Mar 18 23:04:26 2025 CET ModDate: Wed Mar 19 00:08:29 2025 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 7 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 569143 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ONFKLF+AdvPSHN-H Type 1C MacRoman yes yes no 397 0 ONFKMJ+AdvOT34fe1490.B Type 1C WinAnsi yes yes no 400 0 ONFKMH+AdvOTf0129623 Type 1C WinAnsi yes yes no 403 0 PCKNOB+AdvPS3FDD77 Type 1C WinAnsi yes yes no 398 0 PCKOIO+Arial-BoldMT Type 1C WinAnsi yes yes no 411 0 PCKOIP+ArialMT Type 1C Custom yes yes yes 408 0 ONFLMN+Arial-ItalicMT Type 1C WinAnsi yes yes no 418 0 PCKOKB+AdvP4C4E74 Type 1C Custom yes yes no 423 0 ONFKMI+AdvOTf0129623+20 Type 1C WinAnsi yes yes no 425 0 ONFKML+AdvOTf0129623+fb Type 1C Custom yes yes yes 430 0 ONFLBO+AdvPS480274 Type 1C WinAnsi yes yes no 271 0 ONFKLF+AdvPSHN-H Type 1C MacRoman yes yes no 244 0 ONFKLG+AdvOT27e5dc71 Type 1C WinAnsi yes yes no 243 0 ONFKMH+AdvOTf0129623 Type 1C WinAnsi yes yes no 263 0 ONFKMI+AdvOTf0129623+20 Type 1C WinAnsi yes yes no 264 0 ONFKMJ+AdvOT34fe1490.B Type 1C WinAnsi yes yes no 230 0 PCKOKB+AdvP4C4E74 Type 1C WinAnsi yes yes no 227 0 ONFKML+AdvOTf0129623+fb Type 1C Custom yes yes yes 228 0 ONFKMM+AdvOT3a037357.I Type 1C WinAnsi yes yes no 229 0 ONFKMN+AdvOT863180fb Type 1C WinAnsi yes yes no 252 0 ONFKMO+AdvPSMP13 Type 1C WinAnsi yes yes no 245 0 ONFKMP+AdvOT34fe1490.B+fb Type 1C Custom yes yes yes 246 0 ONFLHN+AdvOT863180fb+22 Type 1C Custom yes yes no 278 0 PCKOIP+ArialMT Type 1C WinAnsi yes yes no 281 0 ONFLMN+Arial-ItalicMT Type 1C WinAnsi yes yes no 285 0 ONFLNO+AdvOT3a037357.I+20 Type 1C WinAnsi yes yes no 292 0 ONFLOO+AdvOT34fe1490.B+20 Type 1C WinAnsi yes yes no 287 0 ONFLOP+AdvOT3a037357.I+fb Type 1C Custom yes yes yes 294 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-10-02 03:53:03 CEST RepresentationInformation: 319533.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-10-01 12:40:10 CEST Size: 569143 Format: PDF Version: 1.7 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ErrorMessage: Invalid indirect destination - referenced object 'aff2' cannot be found ID: PDF-HUL-149 ErrorMessage: Invalid indirect destination - referenced object 'aff1' cannot be found ID: PDF-HUL-149 ErrorMessage: Invalid indirect destination - referenced object 'aff4' cannot be found ID: PDF-HUL-149 ErrorMessage: Invalid indirect destination - referenced object 'aff3' cannot be found ID: PDF-HUL-149 ErrorMessage: Invalid indirect destination - referenced object 'appsec1' cannot be found ID: PDF-HUL-149 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff2' cannot be found ID: PDF-HUL-122 Offset: 549324 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff3' cannot be found ID: PDF-HUL-122 Offset: 549324 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'appsec1' cannot be found ID: PDF-HUL-122 Offset: 549324 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff4' cannot be found ID: PDF-HUL-122 Offset: 549324 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'aff1' cannot be found ID: PDF-HUL-122 Offset: 549324 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 505 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Hemodynamic profile of terlipressin and octreotide in patients with cirrhosis and portal hypertension: a randomized, single ... Destination: titlink1 Children: Item: Title: Introduction Destination: flink1 Children: Item: Title: Patients and methods Destination: slink1 Item: Title: Statistical analysis Destination: flink2 Item: Title: Results Destination: flink3 Item: Title: Discussion Destination: flink4 Item: Title: Abbreviations Destination: flink5 Item: Title: Financial support Destination: flink6 Item: Title: Conflicts of interest Destination: flink7 Item: Title: Authors’ contributions Destination: flink8 Item: Title: Data availability statement Destination: flink9 Item: Title: Supplementary data Destination: flink10 Item: Title: References Destination: blink1 Info: Title: Hemodynamic profile of terlipressin and octreotide in patients with cirrhosis and portal hypertension: a randomized, single-blind clinical trial Author: Valeria Perez-Campuzano Subject: Journal of Hepatology, 7 (2025) 101325. doi:10.1016/j.jhepr.2024.101325 Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Tue Mar 18 23:34:26 CET 2025 ModDate: Wed Mar 19 00:38:29 CET 2025 ID: 0xa0b8063f29b7ddae77d5c82bb81a4943, 0xdf0e06ace1554e4c9779c9c74514b84f Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 127 ImageHeight: 60 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 95 ImageHeight: 50 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 27 ImageHeight: 26 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 3 ImageHeight: 5 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 138 ImageHeight: 120 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 70 ImageHeight: 96 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 22 ImageHeight: 35 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 18 ImageHeight: 17 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 70 ImageHeight: 4 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 11 ImageHeight: 11 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 13 ImageHeight: 13 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 74 ImageHeight: 90 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 54 ImageHeight: 17 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 9 ImageHeight: 56 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 54 ImageHeight: 48 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 2 ImageHeight: 17 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 23 ImageHeight: 9 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 3 ImageHeight: 3 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 23 ImageHeight: 35 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 162 ImageHeight: 197 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 2 ImageHeight: 135 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 35 ImageHeight: 48 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 142 ImageHeight: 106 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 161 ImageHeight: 150 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 20 ImageHeight: 12 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 28 ImageHeight: 27 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 143 ImageHeight: 164 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 180 ImageHeight: 124 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: ONFKMH+AdvOTf0129623 FontSubset: true FirstChar: 37 LastChar: 243 FontDescriptor: FontName: ONFKMH+AdvOTf0129623 Flags: Nonsymbolic FontBBox: -52, -208, 906, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFKMI+AdvOTf0129623+20 FontSubset: true FirstChar: 134 LastChar: 151 FontDescriptor: FontName: ONFKMI+AdvOTf0129623+20 Flags: Nonsymbolic FontBBox: -156, -145, 1072, 718 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFKLF+AdvPSHN-H FontSubset: true FirstChar: 44 LastChar: 222 FontDescriptor: FontName: ONFKLF+AdvPSHN-H Flags: Nonsymbolic FontBBox: -166, -229, 1093, 812 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: PCKNOB+AdvPS3FDD77 FontSubset: true FirstChar: 46 LastChar: 46 FontDescriptor: FontName: PCKNOB+AdvPS3FDD77 Flags: Nonsymbolic FontBBox: 0, -208, 1145, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFLBO+AdvPS480274 FontSubset: true FirstChar: 45 LastChar: 45 FontDescriptor: FontName: ONFLBO+AdvPS480274 Flags: Nonsymbolic FontBBox: 0, -208, 1354, 791 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFKMJ+AdvOT34fe1490.B FontSubset: true FirstChar: 58 LastChar: 117 FontDescriptor: FontName: ONFKMJ+AdvOT34fe1490.B Flags: Nonsymbolic FontBBox: -52, -208, 937, 968 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFKMH+AdvOTf0129623 FontSubset: true FirstChar: 40 LastChar: 237 FontDescriptor: FontName: ONFKMH+AdvOTf0129623 Flags: Nonsymbolic FontBBox: -52, -208, 906, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFLHN+AdvOT863180fb+22 FontSubset: true FirstChar: 21 LastChar: 21 FontDescriptor: FontName: ONFLHN+AdvOT863180fb+22 Flags: Nonsymbolic FontBBox: -20, -208, 770, 885 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: PCKOIP+ArialMT FontSubset: true FirstChar: 2 LastChar: 121 FontDescriptor: FontName: PCKOIP+ArialMT Flags: Symbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: PCKOIP+ArialMT FontSubset: true FirstChar: 32 LastChar: 149 FontDescriptor: FontName: PCKOIP+ArialMT Flags: Symbolic FontBBox: -665, -325, 2000, 1040 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: PCKOIO+Arial-BoldMT FontSubset: true FirstChar: 32 LastChar: 122 FontDescriptor: FontName: PCKOIO+Arial-BoldMT Flags: Nonsymbolic FontBBox: -628, -376, 2000, 1056 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFLMN+Arial-ItalicMT FontSubset: true FirstChar: 112 LastChar: 112 FontDescriptor: FontName: ONFLMN+Arial-ItalicMT Flags: Nonsymbolic, Italic FontBBox: -517, -325, 1359, 998 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFLOO+AdvOT34fe1490.B+20 FontSubset: true FirstChar: 146 LastChar: 146 FontDescriptor: FontName: ONFLOO+AdvOT34fe1490.B+20 Flags: Nonsymbolic FontBBox: -156, -166, 1072, 718 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFLMN+Arial-ItalicMT FontSubset: true FirstChar: 112 LastChar: 112 FontDescriptor: FontName: ONFLMN+Arial-ItalicMT Flags: Nonsymbolic, Italic FontBBox: -517, -325, 1359, 998 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: PCKOKB+AdvP4C4E74 FontSubset: true FirstChar: 106 LastChar: 106 FontDescriptor: FontName: PCKOKB+AdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFKML+AdvOTf0129623+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: ONFKML+AdvOTf0129623+fb Flags: Symbolic FontBBox: 0, 0, 500, 718 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ONFLNO+AdvOT3a037357.I+20 FontSubset: true FirstChar: 146 LastChar: 151 FontDescriptor: FontName: ONFLNO+AdvOT3a037357.I+20 Flags: Nonsymbolic FontBBox: -156, -145, 1010, 718 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFKMM+AdvOT3a037357.I FontSubset: true FirstChar: 40 LastChar: 243 FontDescriptor: FontName: ONFKMM+AdvOT3a037357.I Flags: Nonsymbolic FontBBox: -125, -208, 979, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFKMJ+AdvOT34fe1490.B FontSubset: true FirstChar: 38 LastChar: 121 FontDescriptor: FontName: ONFKMJ+AdvOT34fe1490.B Flags: Nonsymbolic FontBBox: -52, -208, 937, 968 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFLOP+AdvOT3a037357.I+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: ONFLOP+AdvOT3a037357.I+fb Flags: Symbolic FontBBox: 19, 0, 562, 718 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: PCKOKB+AdvP4C4E74 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: PCKOKB+AdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: ONFKMI+AdvOTf0129623+20 FontSubset: true FirstChar: 150 LastChar: 150 FontDescriptor: FontName: ONFKMI+AdvOTf0129623+20 Flags: Nonsymbolic FontBBox: -156, -145, 1072, 718 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFKML+AdvOTf0129623+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: ONFKML+AdvOTf0129623+fb Flags: Symbolic FontBBox: 0, 0, 500, 718 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ONFKLG+AdvOT27e5dc71 FontSubset: true FirstChar: 113 LastChar: 113 FontDescriptor: FontName: ONFKLG+AdvOT27e5dc71 Flags: Nonsymbolic FontBBox: 0, -187, 989, 739 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFKLF+AdvPSHN-H FontSubset: true FirstChar: 44 LastChar: 222 FontDescriptor: FontName: ONFKLF+AdvPSHN-H Flags: Nonsymbolic FontBBox: -166, -229, 1093, 812 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: ONFKMO+AdvPSMP13 FontSubset: true FirstChar: 108 LastChar: 108 FontDescriptor: FontName: ONFKMO+AdvPSMP13 Flags: Serif, Nonsymbolic FontBBox: 0, -302, 958, 802 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ONFKMP+AdvOT34fe1490.B+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: ONFKMP+AdvOT34fe1490.B+fb Flags: Symbolic FontBBox: 0, 0, 552, 708 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ONFKMN+AdvOT863180fb FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: ONFKMN+AdvOT863180fb Flags: Nonsymbolic FontBBox: -72, -250, 1041, 979 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1016/j.jhepr.2024.101325 Hemodynamic profile of terlipressin and octreotide in patients with cirrhosis and portal hypertension: a randomized, single-blind clinical trial Valeria Perez-Campuzano Pol Olivas José Ferrusquía-Acosta Sonia Torres Roger Borras Anna Baiges Lara Orts Pamela Vizcarra Maria-Angeles Falga Joana Codina Sarah Shalaby Asunción Ojeda Fanny Turon Virginia Hernández-Gea Andrés Cárdenas Juan-Carlos García-Pagán Portal hypertension Cirrhosis Hepatic hemodynamics terlipressin Journal of Hepatology, 7 (2025) 101325. doi:10.1016/j.jhepr.2024.101325 The Authors journal Journal of Hepatology © 2025 The Authors. Published by Elsevier B.V. on behalf of European Association for the Study of the Liver (EASL). 2589-5559 7 4 April 2025 101325 101325 10.1016/j.jhepr.2024.101325 https://doi.org/10.1016/j.jhepr.2024.101325 2010-04-23 true 10.1016/j.jhepr.2024.101325 elsevier.com sciencedirect.com VoR 7.0.1 10.1016/j.jhepr.2024.101325 noindex 2010-04-23 true sciencedirect.com elsevier.com Elsevier 2025-03-19T03:34:26+05:30 2025-03-19T04:38:29+05:30 2025-03-19T04:38:29+05:30 True 1 https://www.elsevier.com/tdm/tdmrep-policy.json Acrobat Distiller 8.1.0 (Windows) uuid:739f2801-3f22-4abc-bb81-377fa1f9340d uuid:7b14aae2-4d18-4cd7-a3fb-2db80b02cb73 http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 42, 577, 107, 585 Annotation: Subtype: Link Rect: 187, 577, 257, 585 Annotation: Subtype: Link Rect: 261, 577, 332, 585 Annotation: Subtype: Link Rect: 42, 46, 177, 53 Annotation: Subtype: Link Rect: 93, 24, 251, 31 Annotation: Subtype: Link Rect: 498, 728, 577, 743 Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 134, 640, 137, 648 Destination: null Annotation: Subtype: Link Rect: 178, 640, 182, 648 Destination: null Annotation: Subtype: Link Rect: 271, 640, 275, 648 Destination: null Annotation: Subtype: Link Rect: 325, 640, 328, 648 Destination: null Annotation: Subtype: Link Rect: 381, 640, 384, 648 Destination: null Annotation: Subtype: Link Rect: 386, 640, 389, 648 Destination: null Annotation: Subtype: Link Rect: 439, 640, 443, 648 Destination: null Annotation: Subtype: Link Rect: 481, 640, 484, 648 Destination: null Annotation: Subtype: Link Rect: 547, 640, 550, 648 Destination: null Annotation: Subtype: Link Rect: 115, 630, 118, 638 Destination: null Annotation: Subtype: Link Rect: 173, 630, 177, 638 Destination: null Annotation: Subtype: Link Rect: 234, 630, 237, 638 Destination: null Annotation: Subtype: Link Rect: 298, 630, 302, 638 Destination: null Annotation: Subtype: Link Rect: 352, 630, 355, 638 Destination: null Annotation: Subtype: Link Rect: 445, 630, 448, 638 Destination: null Annotation: Subtype: Link Rect: 515, 630, 518, 638 Destination: null Annotation: Subtype: Link Rect: 519, 630, 520, 638 Destination: 1 Annotation: Subtype: Link Rect: 519, 630, 520, 638 Destination: 1 Annotation: Subtype: Link Rect: 519, 630, 522, 638 Destination: 1 Annotation: Subtype: Link Rect: 524, 630, 527, 638 Destination: 1 Annotation: Subtype: Link Rect: 116, 620, 119, 628 Destination: null Annotation: Subtype: Link Rect: 120, 620, 121, 628 Destination: 1 Annotation: Subtype: Link Rect: 120, 620, 121, 628 Destination: 1 Annotation: Subtype: Link Rect: 120, 620, 123, 628 Destination: 1 Annotation: Subtype: Link Rect: 125, 620, 128, 628 Destination: 1 Annotation: Subtype: Link Rect: 164, 316, 344, 324 Annotation: Subtype: Link Rect: 84, 246, 88, 255 Destination: 138 Annotation: Subtype: Link Rect: 150, 202, 153, 211 Destination: 138 Annotation: Subtype: Link Rect: 425, 279, 436, 288 Destination: 138 Annotation: Subtype: Link Rect: 360, 246, 363, 255 Destination: 138 Annotation: Subtype: Link Rect: 549, 202, 552, 211 Destination: 138 Annotation: Subtype: Link Rect: 95, 107, 148, 113 Annotation: Subtype: Link Rect: 213, 107, 270, 113 Annotation: Subtype: Link Rect: 274, 107, 331, 113 Annotation: Subtype: Link Rect: 42, 90, 167, 96 Annotation: Subtype: Link Rect: 474, 592, 552, 607 Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 95, 718, 99, 727 Destination: 138 Annotation: Subtype: Link Rect: 190, 641, 194, 650 Destination: 138 Annotation: Subtype: Link Rect: 182, 608, 189, 617 Destination: 138 Annotation: Subtype: Link Rect: 512, 674, 520, 683 Destination: 138 Annotation: Subtype: Link Rect: 324, 175, 346, 184 Destination: 92 Annotation: Subtype: Link Rect: 305, 131, 335, 140 Destination: 92 Annotation: Subtype: Link Rect: 305, 76, 327, 85 Destination: 102 Page: Label: 4 Page: Label: 5 Annotations: Annotation: Subtype: Link Rect: 44, 533, 90, 541 Destination: null Annotation: Subtype: Link Rect: 252, 467, 287, 476 Destination: null Annotation: Subtype: Link Rect: 44, 434, 82, 443 Destination: null Annotation: Subtype: Link Rect: 120, 423, 166, 432 Destination: null Annotation: Subtype: Link Rect: 228, 379, 255, 388 Destination: 102 Annotation: Subtype: Link Rect: 96, 346, 132, 355 Destination: null Annotation: Subtype: Link Rect: 44, 313, 68, 322 Destination: 102 Annotation: Subtype: Link Rect: 77, 259, 124, 268 Destination: null Annotation: Subtype: Link Rect: 184, 248, 219, 257 Destination: null Annotation: Subtype: Link Rect: 269, 82, 273, 91 Destination: 138 Annotation: Subtype: Link Rect: 375, 707, 379, 716 Destination: 138 Annotation: Subtype: Link Rect: 463, 641, 467, 650 Destination: 138 Annotation: Subtype: Link Rect: 536, 575, 540, 584 Destination: 138 Annotation: Subtype: Link Rect: 446, 553, 450, 562 Destination: 138 Annotation: Subtype: Link Rect: 489, 323, 496, 332 Destination: 138 Annotation: Subtype: Link Rect: 402, 225, 410, 234 Destination: 138 Annotation: Subtype: Link Rect: 382, 214, 389, 223 Destination: 138 Annotation: Subtype: Link Rect: 445, 148, 448, 157 Destination: 138 Annotation: Subtype: Link Rect: 446, 137, 454, 146 Destination: 138 Annotation: Subtype: Link Rect: 505, 93, 512, 102 Destination: 138 Page: Label: 6 Annotations: Annotation: Subtype: Link Rect: 268, 674, 275, 683 Destination: 138 Annotation: Subtype: Link Rect: 253, 641, 261, 650 Destination: 138 Annotation: Subtype: Link Rect: 284, 575, 291, 584 Destination: 138 Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 42, 705, 141, 712 Annotation: Subtype: Link Rect: 218, 673, 291, 680 Annotation: Subtype: Link Rect: 42, 664, 103, 671 Annotation: Subtype: Link Rect: 56, 609, 291, 616 Annotation: Subtype: Link Rect: 56, 600, 291, 607 Annotation: Subtype: Link Rect: 56, 591, 110, 598 Annotation: Subtype: Link Rect: 56, 582, 291, 589 Annotation: Subtype: Link Rect: 56, 573, 291, 580 Annotation: Subtype: Link Rect: 56, 564, 186, 571 Annotation: Subtype: Link Rect: 56, 555, 291, 562 Annotation: Subtype: Link Rect: 56, 546, 291, 553 Annotation: Subtype: Link Rect: 56, 537, 133, 544 Annotation: Subtype: Link Rect: 56, 528, 291, 535 Annotation: Subtype: Link Rect: 56, 519, 156, 526 Annotation: Subtype: Link Rect: 56, 510, 291, 517 Annotation: Subtype: Link Rect: 56, 501, 230, 508 Annotation: Subtype: Link Rect: 317, 727, 552, 734 Annotation: Subtype: Link Rect: 317, 718, 552, 725 Annotation: Subtype: Link Rect: 317, 709, 431, 716 Annotation: Subtype: Link Rect: 317, 700, 552, 707 Annotation: Subtype: Link Rect: 317, 691, 552, 698 Annotation: Subtype: Link Rect: 317, 682, 450, 689 Annotation: Subtype: Link Rect: 317, 673, 552, 680 Annotation: Subtype: Link Rect: 317, 664, 552, 671 Annotation: Subtype: Link Rect: 317, 655, 372, 662 Annotation: Subtype: Link Rect: 317, 646, 552, 653 Annotation: Subtype: Link Rect: 317, 637, 552, 644 Annotation: Subtype: Link Rect: 317, 628, 540, 635 Annotation: Subtype: Link Rect: 317, 619, 552, 626 Annotation: Subtype: Link Rect: 317, 610, 552, 617 Annotation: Subtype: Link Rect: 317, 601, 552, 608 Annotation: Subtype: Link Rect: 317, 592, 370, 599 Annotation: Subtype: Link Rect: 317, 583, 552, 590 Annotation: Subtype: Link Rect: 317, 574, 552, 581 Annotation: Subtype: Link Rect: 317, 565, 436, 572 Annotation: Subtype: Link Rect: 317, 556, 552, 563 Annotation: Subtype: Link Rect: 317, 547, 552, 554 Annotation: Subtype: Link Rect: 317, 538, 552, 545 Annotation: Subtype: Link Rect: 317, 529, 415, 536 Annotation: Subtype: Link Rect: 317, 520, 552, 527 Annotation: Subtype: Link Rect: 317, 511, 552, 518 Annotation: Subtype: Link Rect: 317, 503, 456, 510 Checksum: 29aa7981 Type: CRC32 Checksum: 743776e8fd48a8c5d321f0f14d66565a Type: MD5 Checksum: d5dac3e60434b77366d6e1d9edf323a1d9496fde Type: SHA-1 Checksum: d6717fe77e8d6d32c9dc175776894f07e9c95e2a3d06bb90c5598157288fc7e5 Type: SHA-256