9fe0f74b83b5ae30b2d3db5fc75283ab SCR_a2025v15p11307.pdf 02884c26ed512a7a870cc4164f3831339db9fe84 SCR_a2025v15p11307.pdf 74d444578e0fb33f65343840e37775a8a425659ca91b34e010adee8b0107d9c2 SCR_a2025v15p11307.pdf Creator: Adobe InDesign 18.3 (Windows) Producer: Adobe PDF Library 17.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Tue Apr 1 09:29:57 2025 CEST ModDate: Wed Apr 2 14:14:32 2025 CEST Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 2812770 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MinionPro-Regular Type 1C Custom yes no yes 31 0 LMRMJS+Corbel CID TrueType Identity-H yes yes yes 34 0 BHOXZM+Wingdings-Regular CID TrueType Identity-H yes yes yes 1183 0 Corbel TrueType WinAnsi yes no yes 35 0 BHOXZM+Corbel-Bold CID TrueType Identity-H yes yes yes 36 0 Corbel-Bold TrueType WinAnsi yes no yes 1224 0 MinionPro-Bold Type 1C WinAnsi yes no yes 32 0 MinionPro-It Type 1C WinAnsi yes no yes 33 0 JWEKCW+STIXMath-Regular Type 1C Custom yes yes yes 147 0 TYCSMC+STIX-Regular Type 1C Custom yes yes yes 195 0 TYCSMC+TimesNewRomanPSMT TrueType WinAnsi yes yes yes 247 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-09-19 03:48:11 CEST RepresentationInformation: SCR_a2025v15p11307.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-09-18 13:44:52 CEST Size: 2812770 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Tagged PDF PDFMetadata: Objects: 1272 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: An ACE2-Fc decoy produced in glycoengineered plants neutralizes ancestral and newly emerging SARS-CoV-2 variants and demonstrates therapeutic efficacy in hamsters Children: Item: Title: Results Children: Item: Title: Plant-derived ACE2-Fc neutralizes a broad spectrum of SARS-CoV-2 variants of concern Item: Title: Development of a non-binding ACE2-Fc mutant as a control for in vivo studies Item: Title: Intranasal application of plant-derived ACE2-Fc reduces weight loss of SARS-CoV-2-infected hamsters Item: Title: Discussion Item: Title: Material and methods Children: Item: Title: Ethics declaration and biosafety statements Item: Title: Production of ACE2-Fc in glycoengineered plants Item: Title: Enzyme-linked immunosorbent assays Item: Title: Differential scanning calorimetry Item: Title: ACE2 activity assays Item: Title: Cells Item: Title: Viruses Item: Title: Virus neutralization assays Item: Title: In vivo experiment Item: Title: Immunohistochemical analysis Item: Title: Evaluation of histopathological changes Item: Title: Statistical analysis Item: Title: References Info: Creator: Adobe InDesign 18.3 (Windows) Producer: Adobe PDF Library 17.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Tue Apr 01 09:29:57 CEST 2025 ModDate: Wed Apr 02 14:14:32 CEST 2025 ID: 0x409d517f48bd699b9f75f35f9555a982, 0x78b52f25ba170e57ef138c5c467877b5 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2008 ImageHeight: 1048 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 2008 ImageHeight: 879 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2008 ImageHeight: 916 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2008 ImageHeight: 2359 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1697 ImageHeight: 2363 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1874 ImageHeight: 2363 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Fonts: Type0: Font: BaseFont: LMRMJS+Corbel Encoding: Identity-H ToUnicode: true Font: BaseFont: BHOXZM+Corbel-Bold Encoding: Identity-H ToUnicode: true Font: BaseFont: BHOXZM+Wingdings-Regular Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: MinionPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-Bold Flags: Serif, Nonsymbolic FontBBox: -318, -360, 1684, 1024 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MinionPro-It FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-It Flags: Serif, Nonsymbolic, Italic FontBBox: -201, -360, 1684, 1002 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: JWEKCW+STIXMath-Regular FontSubset: true FirstChar: 31 LastChar: 31 FontDescriptor: FontName: JWEKCW+STIXMath-Regular Flags: Serif, Nonsymbolic FontBBox: -970, -524, 3238, 2566 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: TYCSMC+STIX-Regular FontSubset: true FirstChar: 31 LastChar: 31 FontDescriptor: FontName: TYCSMC+STIX-Regular Flags: Serif, Nonsymbolic FontBBox: -970, -486, 2208, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MinionPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-Regular Flags: Serif, Nonsymbolic FontBBox: -290, -360, 1684, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true TrueType: Font: BaseFont: Corbel FirstChar: 0 LastChar: 255 FontDescriptor: FontName: Corbel Flags: Nonsymbolic FontBBox: -553, -239, 1110, 952 FontFile2: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: TYCSMC+TimesNewRomanPSMT FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: TYCSMC+TimesNewRomanPSMT Flags: Serif, Nonsymbolic FontBBox: -568, -307, 2046, 1040 FontFile2: true Encoding: WinAnsiEncoding ToUnicode: true CIDFontType2: Font: BaseFont: LMRMJS+Corbel CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: LMRMJS+Corbel Flags: Symbolic FontBBox: -553, -239, 1110, 952 FontFile2: true Font: BaseFont: BHOXZM+Corbel-Bold CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: BHOXZM+Corbel-Bold Flags: Symbolic FontBBox: -556, -239, 1155, 952 FontFile2: true Font: BaseFont: BHOXZM+Wingdings-Regular CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: BHOXZM+Wingdings-Regular Flags: Symbolic FontBBox: 0, -211, 1359, 899 FontFile2: true XMP: 2025-04-01T09:29:57+02:00 2025-04-02T14:14:32+02:00 2025-04-02T14:14:32+02:00 Adobe InDesign 18.3 (Windows) uuid:a38e3070-11cc-4bf7-b146-099c9e3d0b63 xmp.did:7c83adf0-08c6-404b-bda7-72637a428208 xmp.id:dbe6094c-2662-614e-9d2a-daeb31555ee8 proof:pdf 1 xmp.iid:c796435e-b326-c749-8245-c9e52e94a21c xmp.did:91c9aa3b-4414-b14d-a033-dd5a65360468 default converted from application/x-indesign to application/pdf Adobe InDesign 18.3 (Windows) 2025-04-01T09:29:57+02:00 converted uuid:d9114860-e6bc-4af4-83d1-35fe494468ad converted to PDF/A-2b pdfToolbox 2025-04-02T13:06:07+02:00 journal 10.1038/s41598-025-95494-w 2010-04-23 true springer.com springerlink.com 2010-04-23 true 10.1038/s41598-025-95494-w springer.com springerlink.com VoR application/pdf Adobe PDF Library 17.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) False 2 B http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI internal A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original. DerivedFrom ResourceRef Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced. http://ns.adobe.com/xap/1.0/sType/Part# stPart Part http://ns.adobe.com/xap/1.0/t/pg/ xmpTPg XMP Paged-Text internal XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents). PlateNames Seq Text http://ns.adobe.com/pdfx/1.3/ pdfx pdfx internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains Seq Text external Mirrors crossmark:CrossmarkDomainExclusive CrossmarkDomainExclusive Text external Mirrors crossmark:MajorVersionDate CrossmarkMajorVersionDate Text internal Mirrors crossmark:DOI doi Text http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text http://crossref.org/crossmark/1.0/ crossmark crossmark internal CrossMarkDomains CrossMarkDomains Seq Text internal CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Usual same as prism:doi DOI Text external The date when a publication was published. MajorVersionDate Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism external The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. aggregationType Text http://www.niso.org/schemas/jav/1.0/ jav NISO external Values for Journal Article Version are one of the following: AO = Author’s Original SMUR = Submitted Manuscript Under Review AM = Accepted Manuscript P = Proof VoR = Version of Record CVoR = Corrected Version of Record EVoR = Enhanced Version of Record journal_article_version Closed Choice of Text Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 378, 227, 381, 215 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 315, 207, 318, 195 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 290, 187, 293, 175 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 299, 167, 302, 155 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 280, 157, 283, 145 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 390, 769, 546, 758 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 481, 676, 556, 658 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 432, 734, 435, 722 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 457, 714, 460, 702 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 235, 654, 238, 642 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 352, 644, 355, 632 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 314, 634, 320, 622 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 352, 624, 358, 612 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 232, 584, 238, 572 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 239, 584, 245, 572 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 280, 574, 286, 562 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 358, 554, 364, 542 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 313, 544, 319, 532 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 322, 544, 328, 532 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 279, 534, 285, 522 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 524, 514, 530, 502 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 486, 432, 490, 420 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 271, 392, 276, 380 Flags: Print AppearanceDictionary: true Destination: 3 Annotation: Subtype: Link Rect: 41, 770, 200, 758 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 357, 704, 361, 692 Flags: Print AppearanceDictionary: true Destination: 40 Annotation: Subtype: Link Rect: 178, 674, 184, 662 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 320, 614, 325, 602 Flags: Print AppearanceDictionary: true Destination: 60 Annotation: Subtype: Link Rect: 479, 554, 485, 542 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 355, 534, 361, 522 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 465, 524, 469, 512 Flags: Print AppearanceDictionary: true Destination: 122 Annotation: Subtype: Link Rect: 416, 514, 420, 502 Flags: Print AppearanceDictionary: true Destination: 122 Annotation: Subtype: Link Rect: 363, 504, 367, 492 Flags: Print AppearanceDictionary: true Destination: 122 Annotation: Subtype: Link Rect: 303, 484, 308, 472 Flags: Print AppearanceDictionary: true Destination: 122 Annotation: Subtype: Link Rect: 41, 770, 200, 758 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 435, 403, 440, 391 Flags: Print AppearanceDictionary: true Destination: 154 Annotation: Subtype: Link Rect: 335, 383, 339, 371 Flags: Print AppearanceDictionary: true Destination: 154 Annotation: Subtype: Link Rect: 322, 373, 326, 361 Flags: Print AppearanceDictionary: true Destination: 154 Annotation: Subtype: Link Rect: 302, 363, 306, 351 Flags: Print AppearanceDictionary: true Destination: 154 Annotation: Subtype: Link Rect: 382, 353, 387, 341 Flags: Print AppearanceDictionary: true Destination: 154 Annotation: Subtype: Link Rect: 403, 313, 407, 301 Flags: Print AppearanceDictionary: true Destination: 165 Annotation: Subtype: Link Rect: 442, 241, 448, 229 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 524, 231, 530, 219 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 534, 211, 537, 199 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 538, 211, 544, 199 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 546, 211, 552, 199 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 183, 131, 189, 119 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 191, 131, 197, 119 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 239, 121, 245, 109 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 193, 101, 197, 89 Flags: Print AppearanceDictionary: true Destination: 40 Annotation: Subtype: Link Rect: 393, 81, 399, 69 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 400, 81, 407, 69 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 410, 81, 416, 69 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 472, 71, 478, 59 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 479, 71, 485, 59 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 489, 71, 495, 59 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 41, 770, 200, 758 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 286, 724, 291, 712 Flags: Print AppearanceDictionary: true Destination: 154 Annotation: Subtype: Link Rect: 548, 724, 554, 712 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 488, 664, 495, 652 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 232, 634, 238, 622 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 240, 634, 246, 622 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 462, 594, 468, 582 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 244, 554, 250, 542 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 252, 554, 258, 542 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 309, 544, 313, 532 Flags: Print AppearanceDictionary: true Destination: 122 Annotation: Subtype: Link Rect: 339, 514, 345, 502 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 347, 514, 353, 502 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 354, 514, 360, 502 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 364, 514, 370, 502 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 533, 504, 539, 492 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 299, 192, 306, 180 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 307, 192, 313, 180 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 401, 182, 407, 170 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 508, 162, 514, 150 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 515, 162, 521, 150 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 317, 102, 323, 90 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 41, 770, 200, 758 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 435, 96, 441, 83 Flags: Print AppearanceDictionary: true Destination: 198 Annotation: Subtype: Link Rect: 41, 770, 200, 758 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 484, 495, 490, 483 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 184, 235, 190, 223 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 451, 235, 457, 223 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 325, 145, 331, 133 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 41, 770, 200, 758 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 41, 770, 200, 758 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 41, 770, 200, 758 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 265, 371, 271, 359 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 362, 351, 368, 339 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 207, 201, 212, 189 Flags: Print AppearanceDictionary: true Destination: 176 Annotation: Subtype: Link Rect: 546, 71, 552, 59 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 352, 713, 357, 703 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 352, 689, 357, 680 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 352, 666, 357, 656 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 352, 642, 357, 632 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 352, 618, 357, 609 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 352, 595, 357, 585 Flags: Print AppearanceDictionary: true Destination: 256 Annotation: Subtype: Link Rect: 41, 770, 200, 758 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 168, 578, 301, 567 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 561, 438, 551 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 364, 544, 496, 534 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 527, 285, 517 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 466, 519, 554, 509 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 510, 199, 500 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 522, 502, 554, 492 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 494, 269, 483 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 522, 485, 554, 475 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 477, 267, 467 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 280, 460, 427, 450 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 443, 315, 433 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 426, 273, 416 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 482, 418, 554, 408 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 410, 226, 399 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 524, 401, 554, 391 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 393, 268, 383 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 288, 376, 411, 366 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 211, 359, 338, 349 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 197, 342, 329, 332 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 283, 326, 395, 315 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 204, 309, 309, 299 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 264, 292, 375, 282 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 239, 275, 371, 265 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 379, 259, 503, 248 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 290, 242, 407, 231 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 300, 225, 432, 215 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 222, 208, 354, 198 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 475, 200, 554, 189 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 191, 233, 181 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 174, 301, 164 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 239, 158, 373, 147 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 297, 141, 396, 131 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 480, 133, 554, 122 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 124, 223, 114 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 257, 107, 379, 97 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 505, 99, 554, 89 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 90, 247, 80 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 537, 82, 554, 72 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 74, 284, 63 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 57, 300, 47 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 41, 770, 200, 758 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 314, 725, 450, 715 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 303, 708, 420, 698 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 459, 692, 554, 681 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 683, 184, 673 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 193, 666, 297, 656 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 319, 650, 451, 639 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 480, 641, 554, 631 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 633, 211, 622 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 485, 624, 554, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 616, 233, 606 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 282, 599, 414, 589 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 352, 582, 480, 572 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 319, 566, 440, 555 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 501, 549, 554, 538 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 540, 237, 530 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 251, 524, 368, 513 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 242, 507, 371, 496 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 406, 490, 554, 480 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 465, 285, 454 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 247, 448, 368, 438 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 535, 440, 554, 429 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 431, 281, 421 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 508, 423, 554, 412 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 168, 414, 247, 404 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 368, 398, 500, 387 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 256, 381, 399, 370 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 364, 453, 354 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 242, 347, 375, 337 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 354, 330, 486, 320 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 270, 314, 389, 303 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 467, 233, 554, 221 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 155, 223, 184, 211 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 243, 223, 359, 211 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 418, 223, 534, 211 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 41, 770, 200, 758 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 494, 668, 552, 656 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 155, 658, 257, 646 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 226, 517, 385, 505 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 41, 770, 200, 758 Flags: Print AppearanceDictionary: true Thumb: true Checksum: 5c15d1e2 Type: CRC32 Checksum: 9fe0f74b83b5ae30b2d3db5fc75283ab Type: MD5 Checksum: 02884c26ed512a7a870cc4164f3831339db9fe84 Type: SHA-1 Checksum: 74d444578e0fb33f65343840e37775a8a425659ca91b34e010adee8b0107d9c2 Type: SHA-256