a031c4bf2df295ebef8949f8b59be4ba uaae048.pdf 0537881982e9808ad8eff0168b74a0395bd8e1e1 uaae048.pdf ca37dba0d1712e4e98d6deeb776efc6bc9981c55f6001cb5ca1e29e6160db681 uaae048.pdf Title: Idiopathic granulomatous mastitis after mRNA vaccination against COVID-19: a possible association? Subject: Doi: 10.1093/bjrcr/uaae048 BJR|Case Reports, 11, 1, 2025 Publication Date: 15/01/2025 Abstract Idiopathic granulomatous mastitis (IGM) is an uncommon benign disease thought to have an autoimmune origin. After massive vaccination against COVID-19, mRNA vaccines have been associated with various possible adverse effects. Among those involving the breast, the most common are ipsilateral axillary lymphadenopathies and transient breast oedema. We present the case of a young woman who developed IGM after mRNA vaccination against COVID-19. We describe the clinical and imaging findings and management of this case, discussing the evidence for a possible link between vaccination and the development of this uncommon inflammatory process and underlining the importance of including this entity in the differential diagnosis in this scenario. 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Subject: Doi: 10.1093/bjrcr/uaae048 BJR|Case Reports, 11, 1, 2025 Publication Date: 15/01/2025 Abstract Idiopathic granulomatous mastitis (IGM) is an uncommon benign disease thought to have an autoimmune origin. After massive vaccination against COVID-19, mRNA vaccines have been associated with various possible adverse effects. Among those involving the breast, the most common are ipsilateral axillary lymphadenopathies and transient breast oedema. We present the case of a young woman who developed IGM after mRNA vaccination against COVID-19. We describe the clinical and imaging findings and management of this case, discussing the evidence for a possible link between vaccination and the development of this uncommon inflammatory process and underlining the importance of including this entity in the differential diagnosis in this scenario. 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Elisenda Vall Vicente Araya Lidia Tortajada Vanessa Escobedo Rosa Nogueiras Javier del Riego Doi: 10.1093/bjrcr/uaae048 BJR|Case Reports, 11, 1, 2025 Publication Date: 15/01/2025 Abstract Idiopathic granulomatous mastitis (IGM) is an uncommon benign disease thought to have an autoimmune origin. After massive vaccination against COVID-19, mRNA vaccines have been associated with various possible adverse effects. Among those involving the breast, the most common are ipsilateral axillary lymphadenopathies and transient breast oedema. We present the case of a young woman who developed IGM after mRNA vaccination against COVID-19. We describe the clinical and imaging findings and management of this case, discussing the evidence for a possible link between vaccination and the development of this uncommon inflammatory process and underlining the importance of including this entity in the differential diagnosis in this scenario. © The Author(s) 2025. 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