c7b0b2dc616254cc0af4509e68545c88 fimmu-15-1512154.pdf 01de97d9b87f67758aa14bcbd7fe208bfcc8ae81 fimmu-15-1512154.pdf 3669eb629aac80e75468a3bf3f19ee00b138c9cf05c06d3afc9d197f966298b7 fimmu-15-1512154.pdf Title: Frailty assessment in adults undergoing allogeneic hematopoietic cell transplantation: insights from a multicenter GETH-TC study to optimize outcomes and care Subject: Salas MQ, Solano MT, Baile González M, Acera Gómez M, Fox L, Pérez Artigas MdM, Santamaría A, Quintela González MdC, Sánchez Salinas A, Salmerón Camacho JM, Illana Álvaro V, Abdallahi-Lefdil Z, Cornago Navascues J, Pardo L, Fernández-Luis S, Vega Suárez LP, Villar S, Beorlegui-Murillo P, Esquirol A, Izquierdo García I, Rodríguez González S, Mussetti A, Lavilla E, Lopez-Marín J, Filaferro S, Cedillo Á, Bento L and Sureda A (2024) Frailty assessment in adults undergoing allogeneic hematopoietic cell transplantation: insights from a multicenter GETH-TC study to optimize outcomes and care. Front. Immunol. 15:1512154. doi: 10.3389/fimmu.2024.1512154 Keywords: frailty syndrome; HCT Frailty Scale; allogeneic-HCT; pre-habilitation; survival Author: María Queralt Salas CreationDate: Thu Jan 2 00:54:01 2025 CET ModDate: Thu Jan 2 00:54:01 2025 CET Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 14 Encrypted: no Page size: 595.389 x 841.663 pts (A4) Page rot: 0 File size: 3962772 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- NOGFOH+AdvTTd3a5f740 Type 1C WinAnsi yes yes no 1029 0 NOGFOI+AdvTTd3a5f740+01 Type 1C MacRoman yes yes no 1030 0 NOGFOJ+AdvPSA18C Type 1C WinAnsi yes yes no 1031 0 NOGFOK+AdvTT9b12cd41 Type 1C WinAnsi yes yes no 1036 0 NOGFOL+AdvPSA323 Type 1C WinAnsi yes yes no 1037 0 NOGFOM+AdvTT9b12cd41+01 Type 1C MacRoman yes yes no 1038 0 NOGFON+AdvTT9b12cd41+20 Type 1C WinAnsi yes yes no 1039 0 NOGFPN+AdvTT2c8ce45a Type 1C WinAnsi yes yes no 1042 0 NOGFPO+AdvTTd168d80a.I Type 1C WinAnsi yes yes no 1043 0 NOGFPP+AdvTTf90d833a.I+03 Type 1C Custom yes yes yes 1044 0 NOGGAA+AdvTT9b12cd41+fb Type 1C Custom yes yes yes 1045 0 NOGHKG+AdvOT1ef757c0 Type 1C WinAnsi yes yes no 222 0 NOGHKH+AdvOT1ef757c0+fb Type 1C Custom yes yes yes 235 0 NOGHKI+AdvOT1ef757c0+20 Type 1C WinAnsi yes yes no 229 0 NOGHKJ+AdvOT7d6df7ab.I Type 1C WinAnsi yes yes no 230 0 NOGHLK+AdvTT58d178b9+03 Type 1C Custom yes yes yes 223 0 NOGHLL+AdvOT1ef757c0+01 Type 1C MacRoman yes yes no 236 0 NOGMOK+AdvTTd3a5f740+fb Type 1C Custom yes yes yes 240 0 NOGMPL+AdvTT2c8ce45a+fb Type 1C Custom yes yes yes 242 0 NOGMPM+AdvOT1ef757c0+22 Type 1C Custom yes yes yes 243 0 NOHLKM+AdvTTd3a5f740+20 Type 1C WinAnsi yes yes no 247 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-11-27 04:05:38 CET RepresentationInformation: fimmu-15-1512154.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-11-26 17:04:58 CET Size: 3962772 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 1123 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Frailty assessment in adults undergoing allogeneic hematopoietic cell transplantation: insights from a multicenter GETH-TC study to optimize outcomes and care Destination: bmark_307030769 Children: Item: Title: Introduction Destination: s1 Item: Title: Methods Destination: s2 Children: Item: Title: Study design, multicenter participation, and patient selection Destination: s2_1 Item: Title: Frailty assessment: implementation of the HCT Frailty Scale Destination: s2_2 Item: Title: Pre-habilitation program Destination: s2_3 Item: Title: Pre-transplant assessment and allo-HCT practices Destination: s2_4 Item: Title: Statistical analysis Destination: s2_5 Item: Title: Results Destination: s3 Children: Item: Title: Frailty assessment implementation Destination: s3_1 Item: Title: Frailty assessment at the first consultation Destination: s3_2 Item: Title: Pre-habilitation and frailty evaluation at HCT admission Destination: s3_3 Item: Title: Frailty at HCT admission and allo-HCT results Destination: s3_4 Item: Title: Frailty syndrome and transplant outcomes Destination: s3_5 Item: Title: Pre-habilitation and transplant outcomes Destination: s3_6 Item: Title: Discussion Destination: s4 Item: Title: Data availability statement Destination: bmark_-1258588262 Item: Title: Ethics statement Destination: bmark_1370551237 Item: Title: Author contributions Destination: bmark_-1208584890 Item: Title: Funding Destination: bmark_1865464027 Item: Title: Acknowledgments Destination: bmark_-366698314 Item: Title: Conflict of interest Destination: bmark_1089982005 Item: Title: Generative AI statement Destination: bmark_-1453097031 Item: Title: Publisher’s note Destination: bmark_-1256977648 Item: Title: Supplementary material Destination: bmark_632582120 Item: Title: References Destination: bmark_2090415954 Info: Title: Frailty assessment in adults undergoing allogeneic hematopoietic cell transplantation: insights from a multicenter GETH-TC study to optimize outcomes and care Author: María Queralt Salas Subject: Salas MQ, Solano MT, Baile González M, Acera Gómez M, Fox L, Pérez Artigas MdM, Santamaría A, Quintela González MdC, Sánchez Salinas A, Salmerón Camacho JM, Illana Álvaro V, Abdallahi-Lefdil Z, Cornago Navascues J, Pardo L, Fernández-Luis S, Vega Suárez LP, Villar S, Beorlegui-Murillo P, Esquirol A, Izquierdo García I, Rodríguez González S, Mussetti A, Lavilla E, Lopez-Marín J, Filaferro S, Cedillo Á, Bento L and Sureda A (2024) Frailty assessment in adults undergoing allogeneic hematopoietic cell transplantation: insights from a multicenter GETH-TC study to optimize outcomes and care. Front. Immunol. 15:1512154. doi: 10.3389/fimmu.2024.1512154 Keywords: frailty syndrome; HCT Frailty Scale; allogeneic-HCT; pre-habilitation; survival CreationDate: Thu Jan 02 00:54:01 CET 2025 ModDate: Thu Jan 02 00:54:01 CET 2025 ID: 0x77bce0342cc904004c20df22374071c4, 0x64d99185e5c24b45aed29c9fd65aec01 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2919 ImageHeight: 577 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 3584 ImageHeight: 3295 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 4540 ImageHeight: 3113 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 4961 ImageHeight: 3180 BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: 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FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: NOGGAA+AdvTT9b12cd41+fb Flags: Symbolic FontBBox: 0, 0, 854, 697 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: NOHLKM+AdvTTd3a5f740+20 FontSubset: true FirstChar: 146 LastChar: 146 FontDescriptor: FontName: NOHLKM+AdvTTd3a5f740+20 Flags: Nonsymbolic FontBBox: -114, -166, 1062, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NOGHKG+AdvOT1ef757c0 FontSubset: true FirstChar: 35 LastChar: 180 FontDescriptor: FontName: NOGHKG+AdvOT1ef757c0 Flags: Serif, Nonsymbolic FontBBox: -20, -250, 947, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NOGHLK+AdvTT58d178b9+03 FontSubset: true FirstChar: 0 LastChar: 0 FontDescriptor: FontName: NOGHLK+AdvTT58d178b9+03 Flags: Symbolic FontBBox: -645, -354, 916, 895 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true XMP: application/pdf María Queralt Salas María Teresa Solano Mónica Baile González Marina Acera Gómez Laura Fox María del Mar Pérez Artigas Ana Santamaría María del Carmen Quintela González Andrés Sánchez Salinas Joaquina M. Salmerón Camacho Verónica Illana Álvaro Zahra Abdallahi-Lefdil Javier Cornago Navascues Laura Pardo Sara Fernández-Luis Leddy Patricia Vega Suárez Sara Villar Patricia Beorlegui-Murillo Albert Esquirol Isabel Izquierdo García Sonia Rodríguez González Alberto Mussetti Esperanza Lavilla Javier Lopez-Marín Silvia Filaferro Ángel Cedillo Leyre Bento Anna Sureda Salas MQ, Solano MT, Baile González M, Acera Gómez M, Fox L, Pérez Artigas MdM, Santamaría A, Quintela González MdC, Sánchez Salinas A, Salmerón Camacho JM, Illana Álvaro V, Abdallahi-Lefdil Z, Cornago Navascues J, Pardo L, Fernández-Luis S, Vega Suárez LP, Villar S, Beorlegui-Murillo P, Esquirol A, Izquierdo García I, Rodríguez González S, Mussetti A, Lavilla E, Lopez-Marín J, Filaferro S, Cedillo Á, Bento L and Sureda A (2024) Frailty assessment in adults undergoing allogeneic hematopoietic cell transplantation: insights from a multicenter GETH-TC study to optimize outcomes and care. Front. Immunol. 15:1512154. doi: 10.3389/fimmu.2024.1512154 Copyright © 2025 Salas, Solano, Baile González, Acera Gómez, Fox, Pérez Artigas, Santamaría, Quintela González, Sánchez Salinas, Salmerón Camacho, Illana Álvaro, Abdallahi-Lefdil, Cornago Navascues, Pardo, Fernández-Luis, Vega Suárez, Villar, Beorlegui-Murillo, Esquirol, Izquierdo García, Rodríguez González, Mussetti, Lavilla, Lopez-Marín, Filaferro, Cedillo, Bento and Sureda. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. frailty syndrome HCT Frailty Scale allogeneic-HCT pre-habilitation survival Frailty assessment in adults undergoing allogeneic hematopoietic cell transplantation: insights from a multicenter GETH-TC study to optimize outcomes and care frailty syndrome; HCT Frailty Scale; allogeneic-HCT; pre-habilitation; survival True https://www.frontiersin.org/legal/copyright-statement 2025-01-02T07:54:01+08:00 2025-01-02T07:54:01+08:00 2025-01-02T07:54:01+08:00 uuid:6b92f1ba-6c61-4a27-9438-b77159358b00 uuid:12d6331a-23cd-4cd1-8cd9-257e0ec6030d Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 221, 685, 485, 706 Annotation: Subtype: Link Rect: 221, 660, 438, 681 Annotation: Subtype: Link Rect: 221, 635, 402, 656 Annotation: Subtype: Link Rect: 221, 610, 523, 631 Annotation: Subtype: Link Rect: 221, 585, 517, 606 Annotation: Subtype: Link Rect: 221, 560, 499, 581 Annotation: Subtype: Link Rect: 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