2b61a87dbb5f27218f9c96a5c29b18a2 320043.pdf 545395b9d0790b2d3e2033d7199ec2f4da5870dd 320043.pdf 75ea0a6cdd9dc75158d414fbbe62e0a2663f45d5b7020df40c9fcb5e8a49e208 320043.pdf Title: Effectiveness of the SYNCHRONIZE + Brief Intervention in Improving Mediterranean Diet Adherence, Nutritional Quality and Intake Pattern in Persons with Fibromyalgia and Chronic Fatigue Syndrome Subject: Background: Multidisciplinary lifestyle interventions are being researched to treat fibromyalgia. However, the impact of nutrition as a key treatment component is little studied. This study aimed to evaluate the effectiveness of the SYNCHRONIZE + lifestyle multidisciplinary intervention in improving adherence to the Mediterranean diet, nutrition quality and dietary intake pattern in persons with fibromyalgia and chronic fatigue syndrome. Methods: A pragmatic randomized clinical trial was conducted in primary care. Data were collected using the 17-item energy-restricted Mediterranean Adherence Screener (er-MEDAS), the food frequency questionnaire (sFFQ) and the 24 h recall questionnaire (24 HR), in addition to chrono-nutritional, anthropometric, and body composition data, at baseline and 3-, 6-, and 12- month follow-up visits, and statistically analyzed. Results: A total of 158 participants were evaluated. Results showed the effectiveness of the intervention in improving adherence to the Mediterranean diet. The adherence depended on the group-time interaction being positive and significant at 3 and 6 months post-intervention in the INT group and on the participant age and educational level. Specifically, the intake of legumes, fruits, vegetables, nuts and blue fish was increased, while the intake of sweets and pastries, butter and cream and red and processed meat was reduced. Furthermore, the intake of chips and candies was also reduced, and the consumption of fermented food (yogurts, cheese, kefir) increased. Thus, general diet quality improved. Interestingly, the intake of key nutrients such as protein and iron increased. Furthermore, the number of night eaters was decreased significantly. Muscle mass index was also improved in the intervention group. These results were maintained in the medium to long term. Conclusion: SYNCHRONIZE + is a brief, low-cost, multidisciplinary intervention effective in improving adherence to the Mediterranean diet and improving nutritional and dietary intake patterns in persons with fibromyalgia and chronic fatigue syndrome. Further evaluation of the effect on quality of life and symptoms is needed. Keywords: nutritional intervention; fibromyalgia; mediterranean diet; chronic fatigue syndrome; nutritional quality; dietary patterns Author: Noèlia Carrasco-Querol, Lorena Cabricano-Canga, Nerea Bueno Hernández, Carme Martín-Borràs, Alessandra Queiroga Gonçalves, Anna Vila-Martí, Blanca Ribot, Judit Solà, Carme Valls-Llobet, Rosa Caballol Angelats, Pilar Montesó-Curto, Elisabet Castro Blanco, Macarena Pozo Ariza, Sandra Carreres Rey, Laura Pla Pagà, Mònica Dearos Sanchís, José Fernández-Sáez, M. Rosa Dalmau Llorca and Carina Aguilar Martín Creator: LaTeX with hyperref Producer: pdfTeX-1.40.25 CreationDate: Wed Dec 25 03:32:55 2024 CET ModDate: Wed Dec 25 03:54:27 2024 CET Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 24 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 3844421 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ILBFIC+VnURWPalladioL-Bold Type 1 Custom yes yes yes 10 0 RIZWOT+URWPalladioL-Roma Type 1 Custom yes yes yes 16 0 OZYXLV+URWPalladioL-Bold Type 1 Custom yes yes yes 22 0 EYINZB+URWPalladioL-Ital Type 1 Custom yes yes yes 27 0 IVTCMY+VnURWPalladioL Type 1 Custom yes yes yes 32 0 VBAQIR+CMSY10 Type 1 Builtin yes yes yes 67 0 LDBMDF+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 79 0 LDBMEG+PalatinoLinotype CID TrueType Identity-H yes yes yes 82 0 LDBMEH+PalatinoLinotype TrueType WinAnsi yes yes no 88 0 LDBMEJ+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 91 0 LDBNBF+PalatinoLinotype TrueType MacRoman yes yes no 94 0 RFCXIG+URWPalladioL-BoldItal Type 1 Custom yes yes yes 105 0 LDBMDF+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 117 0 LDBMEG+PalatinoLinotype CID TrueType Identity-H yes yes yes 120 0 LDBMEH+PalatinoLinotype TrueType WinAnsi yes yes no 126 0 LDBMEJ+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 129 0 LDBNBF+PalatinoLinotype TrueType MacRoman yes yes no 132 0 LDCAPP+PalatinoLinotype,BoldItalic TrueType WinAnsi yes yes no 135 0 LDBMDF+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 156 0 LDBMEG+PalatinoLinotype CID TrueType Identity-H yes yes yes 159 0 LDBMEH+PalatinoLinotype TrueType WinAnsi yes yes no 165 0 LDBMEJ+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 168 0 LDBNBF+PalatinoLinotype TrueType MacRoman yes yes no 171 0 LDBMDF+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 182 0 LDBMEG+PalatinoLinotype CID TrueType Identity-H yes yes yes 185 0 LDBMEH+PalatinoLinotype TrueType WinAnsi yes yes no 191 0 LDBMEJ+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 194 0 LDBNBF+PalatinoLinotype TrueType MacRoman yes yes no 197 0 OVNEXW+EURM10 Type 1 Builtin yes yes yes 220 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-09-30 03:47:47 CEST RepresentationInformation: 320043.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-09-29 14:33:45 CEST Size: 3844421 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 482 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Materials and Methods Destination: section.2 Children: Item: Title: Study Design and Objective Destination: subsection.2.1 Item: Title: Study Population Destination: subsection.2.2 Item: Title: SYNCHRONIZE + Intervention Destination: subsection.2.3 Item: Title: Data Collection and Outcomes Destination: subsection.2.4 Item: Title: Statistical Analysis Destination: subsection.2.5 Item: Title: Results Destination: section.3 Children: Item: Title: The Study Sample Destination: subsection.3.1 Item: Title: Mediterranean Diet Adherence Outcomes Destination: subsection.3.2 Item: Title: Food Intake Frequency and Nutritional Quality Destination: subsection.3.3 Item: Title: Dietary Intake Patterns Destination: subsection.3.4 Item: Title: Anthropometry and Body Composition Destination: subsection.3.5 Item: Title: Discussion Destination: section.4 Children: Item: Title: Mediterranean Diet Adherence Destination: subsection.4.1 Item: Title: Food Intake Frequency and Nutritional Quality Destination: subsection.4.2 Item: Title: Dietary Intake Patterns Destination: subsection.4.3 Item: Title: Anthropometry and Body Composition Destination: subsection.4.4 Item: Title: Study Limitations Destination: subsection.4.5 Item: Title: SYNCHRONIZE + Intervention Destination: subsection.4.6 Item: Title: Conclusions Destination: section.5 Item: Title: References Destination: section.6 Info: Title: Effectiveness of the SYNCHRONIZE + Brief Intervention in Improving Mediterranean Diet Adherence, Nutritional Quality and Intake Pattern in Persons with Fibromyalgia and Chronic Fatigue Syndrome Author: Noèlia Carrasco-Querol, Lorena Cabricano-Canga, Nerea Bueno Hernández, Carme Martín-Borràs, Alessandra Queiroga Gonçalves, Anna Vila-Martí, Blanca Ribot, Judit Solà, Carme Valls-Llobet, Rosa Caballol Angelats, Pilar Montesó-Curto, Elisabet Castro Blanco, Macarena Pozo Ariza, Sandra Carreres Rey, Laura Pla Pagà, Mònica Dearos Sanchís, José Fernández-Sáez, M. Rosa Dalmau Llorca and Carina Aguilar Martín Subject: Background: Multidisciplinary lifestyle interventions are being researched to treat fibromyalgia. However, the impact of nutrition as a key treatment component is little studied. This study aimed to evaluate the effectiveness of the SYNCHRONIZE + lifestyle multidisciplinary intervention in improving adherence to the Mediterranean diet, nutrition quality and dietary intake pattern in persons with fibromyalgia and chronic fatigue syndrome. Methods: A pragmatic randomized clinical trial was conducted in primary care. Data were collected using the 17-item energy-restricted Mediterranean Adherence Screener (er-MEDAS), the food frequency questionnaire (sFFQ) and the 24 h recall questionnaire (24 HR), in addition to chrono-nutritional, anthropometric, and body composition data, at baseline and 3-, 6-, and 12- month follow-up visits, and statistically analyzed. Results: A total of 158 participants were evaluated. Results showed the effectiveness of the intervention in improving adherence to the Mediterranean diet. The adherence depended on the group-time interaction being positive and significant at 3 and 6 months post-intervention in the INT group and on the participant age and educational level. Specifically, the intake of legumes, fruits, vegetables, nuts and blue fish was increased, while the intake of sweets and pastries, butter and cream and red and processed meat was reduced. Furthermore, the intake of chips and candies was also reduced, and the consumption of fermented food (yogurts, cheese, kefir) increased. Thus, general diet quality improved. Interestingly, the intake of key nutrients such as protein and iron increased. Furthermore, the number of night eaters was decreased significantly. Muscle mass index was also improved in the intervention group. These results were maintained in the medium to long term. Conclusion: SYNCHRONIZE + is a brief, low-cost, multidisciplinary intervention effective in improving adherence to the Mediterranean diet and improving nutritional and dietary intake patterns in persons with fibromyalgia and chronic fatigue syndrome. Further evaluation of the effect on quality of life and symptoms is needed. 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