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European Journal of Heart Failure expert consensus document Destination: section*.1 Item: Title: Introduction Destination: section*.2 Item: Title: Cardiac rhythm management devices: cornerstones of comprehensive, patient-centred management of heart failure with reduced ejection fraction Destination: section*.3 Item: Title: Integration of implantable device therapy in comprehensive heart failure care Destination: section*.4 Item: Title: Overview of cardiac rhythm management devices and evolving techniques Destination: section*.5 Item: Title: Implantable cardioverter-defibrillators Destination: section*.6 Item: Title: Cardiac physiological pacing Destination: section*.7 Item: Title: Implantable cardioverter-defibrillators for the prevention of sudden cardiac death in patients with heart failure with reduced ejection fraction Destination: section*.8 Item: Title: Risk of sudden cardiac death in heart failure with reduced ejection fraction in the current era of pharmacological therapy Destination: section*.9 Item: Title: Efficacy and safety of implantable cardioverter-defibrillator therapy in heart failure with reduced ejection fraction Destination: section*.10 Item: Title: Secondary prevention trials Destination: section*.11 Item: Title: Primary prevention trials in patients with ischaemic cardiomyopathy Destination: section*.12 Item: Title: Primary prevention trials in patients with non-ischaemic cardiomyopathy Destination: section*.13 Item: Title: Observational studies Destination: section*.14 Item: Title: Eligibility criteria for implantable cardioverter-defibrillator therapy in clinical practice guidelines Destination: section*.15 Item: Title: What determines the mortality benefit of implantable cardioverter-defibrillator therapy? Destination: section*.16 Item: Title: Personalized sudden cardiac death risk stratification Destination: section*.17 Item: Title: Timing of referral for implantable cardioverter-defibrillator implantation: the need for an individualized approach Destination: section*.18 Item: Title: Cardiac resynchronization therapy in patients with heart failure with reduced ejection fraction Destination: section*.19 Item: Title: Efficacy and safety of cardiac resynchronization therapy in heart failure with reduced ejection fraction Destination: section*.20 Item: Title: Eligibility criteria for cardiac resynchronization therapy in clinical practice guidelines Destination: section*.21 Item: Title: A common misconception: the concept of `non-responder' Destination: section*.22 Item: Title: Reverse cardiac remodelling by guideline-directed medications in patients eligible for cardiac resynchronization therapy Destination: section*.23 Item: Title: Timing of referral for cardiac resynchronization therapy implantation Destination: section*.24 Item: Title: Cardiac resynchronization therapy (CRT)-defibrillator versus CRT-pacemaker in patients with heart failure with reduced ejection fraction Destination: section*.25 Item: Title: The patient's perspective Destination: section*.26 Item: Title: Integration of cardiac rhythm management devices in heart failure management: practical recommendations Destination: section*.27 Item: Title: Conclusion and future perspectives Destination: section*.28 Item: Title: Supplementary Information Destination: section*.29 Item: Title: Acknowledgements Destination: section*.30 Item: Title: Funding Destination: section*.31 Item: Title: References Destination: ssectioncnt.1 Info: Title: Cardiac rhythm devices in HFrEF ‒ role, timing, and optimal use in contemporary practice Author: Subject: Keywords: Creator: LaTeX with hyperref package Producer: Acrobat Distiller 25.0 (Windows) CreationDate: Fri Aug 15 12:52:03 CEST 2025 ModDate: Fri Aug 15 12:52:03 CEST 2025 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