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Destination: mk:H1_2 Children: Item: Title: 2.1 Protein design and three-dimensional modelling and visualization Destination: mk:H2_1 Item: Title: 2.2 Protein production and purification Destination: mk:H2_2 Item: Title: 2.3 Formation of microscale SGs Destination: mk:H2_3 Item: Title: 2.4 Physicochemical characterization of recombinant proteins and SGs Destination: mk:H2_4 Item: Title: 2.5 Determination of protein release from SGs Destination: mk:H2_5 Item: Title: 2.6 In vitro proliferation studies in NIH-3 ​T3 cells Destination: mk:H2_6 Item: Title: 2.7 In vitro toxicity studies in HeLa cells Destination: mk:H2_7 Item: Title: 2.8 In vivo wound healing studies in rats Destination: mk:H2_8 Item: Title: 2.9 Gross necropsy and histopathological analysis Destination: mk:H2_9 Item: Title: 2.10 Statistical analysis and data visualization Destination: mk:H2_10 Item: Title: 3 Results Destination: mk:H1_3 Item: Title: 4 Discussion Destination: mk:H1_4 Item: Title: 5 Conclusion Destination: 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International Journal of Biological Macromolecules, 329 (2025) 147730. doi:10.1016/j.ijbiomac.2025.147730 Biomaterials Recombinant proteins FGF Slow release Drug delivery Self-disintegrating protein-leaking microparticles for topical protein delivery Eric Voltà-Durán Julieta M. Sánchez Marianna T.P. Favaro Genís Martínez-Cuentra Estefanía Contreras Angela di Somma Hèctor López-Laguna Ugutz Unzueta Isolda Casanova Ramón Mangues Antonio Villaverde Esther Vázquez VoR 24th September 2025 Acrobat Distiller 8.1.0 (Windows) Biomaterials,Recombinant proteins,FGF,Slow release,Drug delivery 24th September 2025 10.1016/j.ijbiomac.2025.147730 noindex journal © 2025 The Authors. Published by Elsevier B.V. 2025-11-01 1 November 2025 10.1016/j.ijbiomac.2025.147730 0141-8130 P1 147730 International Journal of Biological Macromolecules 147730 https://doi.org/10.1016/j.ijbiomac.2025.147730 329 https://www.elsevier.com/tdm/tdmrep-policy.json 1 2025-09-24T00:56:52 Elsevier 2025-09-24T06:21:31 2025-09-24T06:21:31 uuid:1b499bed-4ce8-4c0c-b682-0d58baae1cbe uuid:b6ed5266-03cb-4855-90c0-636283357f42 True Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 118, 576, 122, 587 Flags: Print Destination: 1660 Annotation: Subtype: Link Rect: 124, 576, 129, 587 Flags: Print Destination: 1660 Annotation: Subtype: Link Rect: 131, 576, 135, 587 Flags: Print Destination: 1660 Annotation: Subtype: Link Rect: 138, 576, 142, 587 Flags: Print Destination: 1660 Annotation: Subtype: Link Rect: 145, 576, 149, 587 Flags: Print Destination: 1660 Annotation: Subtype: Link Rect: 246, 576, 250, 587 Flags: Print Destination: 1660 Annotation: Subtype: Link Rect: 253, 576, 257, 587 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