ea2bd8be2959f4e3b38631a4ee86290c  AMI_a2025v7n13.pdf
bcf0c815c91799ef208efc20875cb9f229a22f8a  AMI_a2025v7n13.pdf
4bec86dab8aa11840b783cf387dd1500a87a30453912f22a7530f7f06f74a7cd  AMI_a2025v7n13.pdf

Creator:         Adobe InDesign 18.0 (Windows)
Producer:        Adobe PDF Library 17.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)
CreationDate:    Fri Jan 31 08:41:23 2025 CET
ModDate:         Mon Feb  3 06:18:56 2025 CET
Custom Metadata: yes
Metadata Stream: yes
Tagged:          yes
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           15
Encrypted:       no
Page size:       595.276 x 793.701 pts
Page rot:        0
File size:       3176942 bytes
Optimized:       no
PDF version:     1.4


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
MyriadPro-Light                      Type 1C           Custom           yes no  yes    223  0
MyriadPro-Regular                    Type 1C           Custom           yes no  yes     40  0
MyriadPro-Bold                       Type 1C           WinAnsi          yes no  yes     42  0
MyriadPro-Semibold                   Type 1C           Custom           yes no  yes     44  0
MyriadPro-It                         Type 1C           WinAnsi          yes no  yes   1481  0
MyriadPro-LightIt                    Type 1C           Custom           yes no  yes    230  0
MyriadPro-Bold                       Type 1C           WinAnsi          yes no  yes   1536  0
WarnockPro-Regular                   Type 1C           Custom           yes no  yes     41  0
WarnockPro-It                        Type 1C           Custom           yes no  yes     43  0
MyriadPro-Regular                    Type 1C           WinAnsi          yes no  yes     47  0
MyriadPro-It                         Type 1C           WinAnsi          yes no  yes     50  0
MWBZQA+STIX-Regular                  Type 1C           Custom           yes yes yes     69  0
MyriadPro-Regular                    Type 1C           WinAnsi          yes no  yes    430  0
MyriadPro-It                         Type 1C           WinAnsi          yes no  yes    432  0
XXJNOE+LMMathItalic10-Regular        Type 1C           Custom           yes yes yes     99  0
XXJNOE+LMMathItalic10-Regular        Type 1C           Custom           yes yes yes    100  0
MyriadPro-SemiboldIt                 Type 1C           WinAnsi          yes no  yes    101  0
WarnockPro-Light                     Type 1C           Custom           yes no  yes    102  0
XXJNOE+LMMathItalic7-Regular         Type 1C           Custom           yes yes yes    103  0
XXJNOE+LMMathItalic7-Regular         Type 1C           Custom           yes yes yes    104  0
XXJNOE+LMMathItalic10-Regular        Type 1C           Custom           yes yes yes    105  0
QZEUAS+LMRoman10-Regular             Type 1C           Custom           yes yes yes    106  0
XXJNOE+LMMathItalic10-Regular        Type 1C           Custom           yes yes yes    107  0
XXJNOE+LMMathItalic7-Regular         Type 1C           Custom           yes yes yes    108  0
QZEUAS+LMRoman10-Regular             Type 1C           Custom           yes yes yes    109  0
XXJNOE+LMMathItalic7-Regular         Type 1C           Custom           yes yes yes    110  0
XXJNOE+LMMathItalic7-Regular         Type 1C           Custom           yes yes yes    111  0
QZEUAS+LMRoman10-Regular             Type 1C           Custom           yes yes yes    112  0
XXJNOE+LMRoman7-Regular              Type 1C           Custom           yes yes yes    113  0
XXJNOE+LMRoman7-Regular              Type 1C           Custom           yes yes yes    114  0
XXJNOE+LMMathItalic10-Regular        Type 1C           Custom           yes yes yes    115  0
MWBZQA+LMMathExtension10-Regular     Type 1C           Custom           yes yes yes    116  0
XXJNOE+LMMathItalic10-Regular        Type 1C           Custom           yes yes yes    182  0
QZEUAS+LMRoman10-Regular             Type 1C           Custom           yes yes yes    183  0
XXJNOE+LMMathItalic7-Regular         Type 1C           Custom           yes yes yes    184  0
XXJNOE+LMMathItalic10-Regular        Type 1C           Custom           yes yes yes    185  0
XXJNOE+LMMathItalic10-Regular        Type 1C           Custom           yes yes yes    186  0
QZEUAS+LMRoman10-Regular             Type 1C           Custom           yes yes yes    187  0
XXJNOE+LMMathItalic7-Regular         Type 1C           Custom           yes yes yes    188  0
XXJNOE+LMMathItalic7-Regular         Type 1C           Custom           yes yes yes    189  0
XXJNOE+LMMathItalic10-Regular        Type 1C           Custom           yes yes yes    190  0
XXJNOE+LMMathItalic10-Regular        Type 1C           Custom           yes yes yes    191  0
QZEUAS+TimesNewRomanPSMT             TrueType          WinAnsi          yes yes yes    224  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2025-11-04 05:19:15 CET
 RepresentationInformation: AMI_a2025v7n13.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2025-11-03 15:06:05 CET
  Size: 3176942
  Format: PDF
  Version: 1.4
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Tagged PDF
  PDFMetadata: 
   Objects: 1570
   FreeObjects: 1
   IncrementalUpdates: 0
   DocumentCatalog: 
    ViewerPreferences: 
     HideToolbar: false
     HideMenubar: false
     HideWindowUI: false
     FitWindow: false
     CenterWindow: false
     DisplayDocTitle: false
     NonFullScreenPageMode: UseNone
     Direction: L2R
     ViewArea: CropBox
     ViewClip: CropBox
     PrintArea: CropBox
     PageClip: CropBox
    PageLayout: SinglePage
    PageMode: UseOutlines
    Language: en-US
    Outlines: 
     Item: 
      Title: Characterization of microbiota signatures in Iberian pig strains using machine learning algorithms
      Children: 
       Item: 
        Title: Abstract
       Item: 
        Title: Background
       Item: 
        Title: Methods
        Children: 
         Item: 
          Title: Animals and samples
         Item: 
          Title: DNA extraction and 16 S rRNA gene amplicon sequencing
         Item: 
          Title: Bioinformatic pipeline
         Item: 
          Title: Alpha- and beta-diversity
         Item: 
          Title: Machine learning analysis
          Children: 
           Item: 
            Title: Performance evaluation
           Item: 
            Title: Feature selection
       Item: 
        Title: Differential abundance analysis
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Microbiota composition of the Iberian pig genetic groups
         Item: 
          Title: Classification results with machine learning
         Item: 
          Title: Feature selection and subsequent classification results
   Info: 
    Creator: Adobe InDesign 18.0 (Windows)
    Producer: Adobe PDF Library 17.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)
    CreationDate: Fri Jan 31 08:41:23 CET 2025
    ModDate: Mon Feb 03 06:18:56 CET 2025
   ID: 0x204322d30aee2c1e7ed2da2007a09755, 0x504bfc3b11f0646c30068f1b5d1c2922
   Filters: 
    FilterPipeline: FlateDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 2008
      ImageHeight: 2382
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 2008
      ImageHeight: 2123
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 2008
      ImageHeight: 1133
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 2008
      ImageHeight: 999
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1100
      ImageHeight: 90
      BitsPerSample: 1
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     ImageMask: true
     Decode: 0, 1
     Name: X
   Fonts: 
    Type1: 
     Font: 
      BaseFont: MWBZQA+STIX-Regular
      FontSubset: true
      FirstChar: 31
      LastChar: 31
      FontDescriptor: 
       FontName: MWBZQA+STIX-Regular
       Flags: Serif, Nonsymbolic
       FontBBox: -970, -486, 2208, 1023
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MyriadPro-It
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-It
       Flags: Nonsymbolic, Italic
       FontBBox: -185, -250, 1090, 953
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: MyriadPro-Light
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-Light
       Flags: Nonsymbolic
       FontBBox: -153, -250, 1046, 935
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic10-Regular
      FontSubset: true
      FirstChar: 24
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic10-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -32, -250, 1048, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic10-Regular
      FontSubset: true
      FirstChar: 27
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic10-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -32, -250, 1048, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MyriadPro-SemiboldIt
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-SemiboldIt
       Flags: Nonsymbolic, Italic
       FontBBox: -193, -250, 1164, 972
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: MyriadPro-LightIt
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-LightIt
       Flags: Nonsymbolic, Italic
       FontBBox: -175, -250, 1007, 933
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: WarnockPro-Light
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: WarnockPro-Light
       Flags: Serif, Nonsymbolic
       FontBBox: -176, -515, 1437, 929
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic7-Regular
      FontSubset: true
      FirstChar: 31
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic7-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -1, -250, 1171, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MyriadPro-Regular
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-Regular
       Flags: Nonsymbolic
       FontBBox: -157, -250, 1126, 952
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic7-Regular
      FontSubset: true
      FirstChar: 30
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic7-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -1, -250, 1171, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: WarnockPro-Regular
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: WarnockPro-Regular
       Flags: Serif, Nonsymbolic
       FontBBox: -177, -533, 1474, 950
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic10-Regular
      FontSubset: true
      FirstChar: 31
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic10-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -32, -250, 1048, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MyriadPro-Bold
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-Bold
       Flags: Nonsymbolic
       FontBBox: -163, -250, 1256, 989
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: QZEUAS+LMRoman10-Regular
      FontSubset: true
      FirstChar: 30
      LastChar: 31
      FontDescriptor: 
       FontName: QZEUAS+LMRoman10-Regular
       Flags: Serif, Symbolic
       FontBBox: -430, -290, 1417, 1127
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: WarnockPro-It
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: WarnockPro-It
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -222, -533, 1474, 950
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic10-Regular
      FontSubset: true
      FirstChar: 30
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic10-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -32, -250, 1048, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MyriadPro-Semibold
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-Semibold
       Flags: Nonsymbolic
       FontBBox: -161, -250, 1198, 972
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic7-Regular
      FontSubset: true
      FirstChar: 29
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic7-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -1, -250, 1171, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: QZEUAS+LMRoman10-Regular
      FontSubset: true
      FirstChar: 30
      LastChar: 31
      FontDescriptor: 
       FontName: QZEUAS+LMRoman10-Regular
       Flags: Serif, Symbolic
       FontBBox: -430, -290, 1417, 1127
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic7-Regular
      FontSubset: true
      FirstChar: 29
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic7-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -1, -250, 1171, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic7-Regular
      FontSubset: true
      FirstChar: 31
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic7-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -1, -250, 1171, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: QZEUAS+LMRoman10-Regular
      FontSubset: true
      FirstChar: 29
      LastChar: 31
      FontDescriptor: 
       FontName: QZEUAS+LMRoman10-Regular
       Flags: Serif, Symbolic
       FontBBox: -430, -290, 1417, 1127
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMRoman7-Regular
      FontSubset: true
      FirstChar: 30
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMRoman7-Regular
       Flags: Serif, Symbolic
       FontBBox: -483, -292, 1562, 1124
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMRoman7-Regular
      FontSubset: true
      FirstChar: 30
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMRoman7-Regular
       Flags: Serif, Symbolic
       FontBBox: -483, -292, 1562, 1124
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic10-Regular
      FontSubset: true
      FirstChar: 29
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic10-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -32, -250, 1048, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MWBZQA+LMMathExtension10-Regular
      FontSubset: true
      FirstChar: 30
      LastChar: 31
      FontDescriptor: 
       FontName: MWBZQA+LMMathExtension10-Regular
       Flags: Serif, Symbolic
       FontBBox: -24, -2960, 1454, 772
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic10-Regular
      FontSubset: true
      FirstChar: 31
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic10-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -32, -250, 1048, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: QZEUAS+LMRoman10-Regular
      FontSubset: true
      FirstChar: 31
      LastChar: 31
      FontDescriptor: 
       FontName: QZEUAS+LMRoman10-Regular
       Flags: Serif, Symbolic
       FontBBox: -430, -290, 1417, 1127
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic7-Regular
      FontSubset: true
      FirstChar: 29
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic7-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -1, -250, 1171, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic10-Regular
      FontSubset: true
      FirstChar: 31
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic10-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -32, -250, 1048, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic10-Regular
      FontSubset: true
      FirstChar: 31
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic10-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -32, -250, 1048, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: QZEUAS+LMRoman10-Regular
      FontSubset: true
      FirstChar: 31
      LastChar: 31
      FontDescriptor: 
       FontName: QZEUAS+LMRoman10-Regular
       Flags: Serif, Symbolic
       FontBBox: -430, -290, 1417, 1127
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic7-Regular
      FontSubset: true
      FirstChar: 29
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic7-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -1, -250, 1171, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic7-Regular
      FontSubset: true
      FirstChar: 30
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic7-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -1, -250, 1171, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic10-Regular
      FontSubset: true
      FirstChar: 31
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic10-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -32, -250, 1048, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XXJNOE+LMMathItalic10-Regular
      FontSubset: true
      FirstChar: 31
      LastChar: 31
      FontDescriptor: 
       FontName: XXJNOE+LMMathItalic10-Regular
       Flags: Serif, Symbolic, Italic
       FontBBox: -32, -250, 1048, 750
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
    TrueType: 
     Font: 
      BaseFont: QZEUAS+TimesNewRomanPSMT
      FontSubset: true
      FirstChar: 32
      LastChar: 32
      FontDescriptor: 
       FontName: QZEUAS+TimesNewRomanPSMT
       Flags: Serif, Nonsymbolic
       FontBBox: -568, -307, 2046, 1040
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
   XMP: <x:xmpmeta x:xmptk="Adobe XMP Core 5.6-c142 87.162696, 2019/10/10-02:41:22        " xmlns:x="adobe:ns:meta/">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about="" xmlns:crossmark="http://crossref.org/crossmark/1.0/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:jav="http://www.niso.org/schemas/jav/1.0/" xmlns:pdf="http://ns.adobe.com/pdf/1.3/" xmlns:pdfaExtension="http://www.aiim.org/pdfa/ns/extension/" xmlns:pdfaProperty="http://www.aiim.org/pdfa/ns/property#" xmlns:pdfaSchema="http://www.aiim.org/pdfa/ns/schema#" xmlns:pdfaType="http://www.aiim.org/pdfa/ns/type#" xmlns:pdfaid="http://www.aiim.org/pdfa/ns/id/" xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/" xmlns:prism="http://prismstandard.org/namespaces/basic/2.0/" xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#" xmlns:stRef="http://ns.adobe.com/xap/1.0/sType/ResourceRef#" xmlns:xmp="http://ns.adobe.com/xap/1.0/" xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <xmpMM:InstanceID>uuid:bb205d96-5c17-42ec-9404-2751bf2daecf</xmpMM:InstanceID>
         <xmpMM:OriginalDocumentID>adobe:docid:indd:aca9e6a3-b7bc-11dd-9b31-8d92eded7c31</xmpMM:OriginalDocumentID>
         <xmpMM:DocumentID>xmp.id:ccb0528b-fe80-884f-9cf8-47bba8e932c6</xmpMM:DocumentID>
         <xmpMM:RenditionClass>proof:pdf</xmpMM:RenditionClass>
         <xmpMM:VersionID>1</xmpMM:VersionID>
         <xmpMM:DerivedFrom rdf:parseType="Resource">
            <stRef:instanceID>xmp.iid:fa1f5488-71fb-6c44-8ffd-58cffc7e932f</stRef:instanceID>
            <stRef:documentID>xmp.did:948ff6d0-a8e0-2c4e-a3ab-366c1ea874db</stRef:documentID>
            <stRef:renditionClass>default</stRef:renditionClass>
         </xmpMM:DerivedFrom>
         <xmpMM:History>
            <rdf:Seq>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:parameters>from application/x-indesign to application/pdf</stEvt:parameters>
                  <stEvt:softwareAgent>Adobe InDesign 18.0 (Windows)</stEvt:softwareAgent>
                  <stEvt:when>2025-01-31T08:41:23+01:00</stEvt:when>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:instanceID>uuid:c5e8b1a7-a806-4346-85bc-bdd26c2c33f5</stEvt:instanceID>
                  <stEvt:parameters>converted to PDF/A-2b</stEvt:parameters>
                  <stEvt:softwareAgent>pdfToolbox</stEvt:softwareAgent>
                  <stEvt:when>2025-01-31T09:40:50+01:00</stEvt:when>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:instanceID>uuid:80320f07-7ef9-46a1-a3a1-c9854d8aeeee</stEvt:instanceID>
                  <stEvt:parameters>converted to PDF/A-2b</stEvt:parameters>
                  <stEvt:softwareAgent>pdfToolbox</stEvt:softwareAgent>
                  <stEvt:when>2025-02-03T03:51:43+01:00</stEvt:when>
               </rdf:li>
            </rdf:Seq>
         </xmpMM:History>
         <xmp:CreateDate>2025-01-31T08:41:23+01:00</xmp:CreateDate>
         <xmp:ModifyDate>2025-02-03T06:18:56+01:00</xmp:ModifyDate>
         <xmp:MetadataDate>2025-02-03T06:18:56+01:00</xmp:MetadataDate>
         <xmp:CreatorTool>Adobe InDesign 18.0 (Windows)</xmp:CreatorTool>
         <prism:aggregationType>journal</prism:aggregationType>
         <crossmark:DOI>10.1186/s42523-025-00378-z</crossmark:DOI>
         <crossmark:MajorVersionDate>2010-04-23</crossmark:MajorVersionDate>
         <crossmark:CrossmarkDomainExclusive>true</crossmark:CrossmarkDomainExclusive>
         <crossmark:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>springer.com</rdf:li>
               <rdf:li>springerlink.com</rdf:li>
            </rdf:Seq>
         </crossmark:CrossMarkDomains>
         <pdfx:CrossmarkMajorVersionDate>2010-04-23</pdfx:CrossmarkMajorVersionDate>
         <pdfx:CrossmarkDomainExclusive>true</pdfx:CrossmarkDomainExclusive>
         <pdfx:doi>10.1186/s42523-025-00378-z</pdfx:doi>
         <pdfx:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>springer.com</rdf:li>
               <rdf:li>springerlink.com</rdf:li>
            </rdf:Seq>
         </pdfx:CrossMarkDomains>
         <jav:journal_article_version>VoR</jav:journal_article_version>
         <dc:format>application/pdf</dc:format>
         <pdf:Producer>Adobe PDF Library 17.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)</pdf:Producer>
         <pdf:Trapped>False</pdf:Trapped>
         <pdfaid:part>2</pdfaid:part>
         <pdfaid:conformance>B</pdfaid:conformance>
         <pdfaExtension:schemas>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/xap/1.0/mm/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>xmpMM</pdfaSchema:prefix>
                  <pdfaSchema:schema>XMP Media Management Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>UUID based identifier for specific incarnation of a document</pdfaProperty:description>
                           <pdfaProperty:name>InstanceID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
                           <pdfaProperty:name>OriginalDocumentID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original.</pdfaProperty:description>
                           <pdfaProperty:name>DerivedFrom</pdfaProperty:name>
                           <pdfaProperty:valueType>ResourceRef</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>An unordered array of references to resources that were incorporated, by inclusion or reference, into this document.</pdfaProperty:description>
                           <pdfaProperty:name>Ingredients</pdfaProperty:name>
                           <pdfaProperty:valueType>Bag ResourceRef</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
                  <pdfaSchema:valueType>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaType:description>Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced.</pdfaType:description>
                           <pdfaType:namespaceURI>http://ns.adobe.com/xap/1.0/sType/Part#</pdfaType:namespaceURI>
                           <pdfaType:prefix>stPart</pdfaType:prefix>
                           <pdfaType:type>Part</pdfaType:type>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:valueType>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdf/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdf</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe PDF Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A name object indicating whether the document has been modified to include trapping information</pdfaProperty:description>
                           <pdfaProperty:name>Trapped</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/xap/1.0/t/pg/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>xmpTPg</pdfaSchema:prefix>
                  <pdfaSchema:schema>XMP Paged-Text</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents).</pdfaProperty:description>
                           <pdfaProperty:name>PlateNames</pdfaProperty:name>
                           <pdfaProperty:valueType>Seq Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdfx/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfx</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe Document Info PDF eXtension Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>ID of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXVersion</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXConformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Company creating the PDF</pdfaProperty:description>
                           <pdfaProperty:name>Company</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Date when document was last modified</pdfaProperty:description>
                           <pdfaProperty:name>SourceModified</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:CrosMarkDomains</pdfaProperty:description>
                           <pdfaProperty:name>CrossMarkDomains</pdfaProperty:name>
                           <pdfaProperty:valueType>Seq Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:CrossmarkDomainExclusive</pdfaProperty:description>
                           <pdfaProperty:name>CrossmarkDomainExclusive</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:MajorVersionDate</pdfaProperty:description>
                           <pdfaProperty:name>CrossmarkMajorVersionDate</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:DOI</pdfaProperty:description>
                           <pdfaProperty:name>doi</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.aiim.org/pdfa/ns/id/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfaid</pdfaSchema:prefix>
                  <pdfaSchema:schema>PDF/A ID Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Part of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>part</pdfaProperty:name>
                           <pdfaProperty:valueType>Integer</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Amendment of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>amd</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>conformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://crossref.org/crossmark/1.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>crossmark</pdfaSchema:prefix>
                  <pdfaSchema:schema>crossmark</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>CrossMarkDomains</pdfaProperty:description>
                           <pdfaProperty:name>CrossMarkDomains</pdfaProperty:name>
                           <pdfaProperty:valueType>Seq Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>CrossmarkDomainExclusive</pdfaProperty:description>
                           <pdfaProperty:name>CrossmarkDomainExclusive</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Usual same as prism:doi</pdfaProperty:description>
                           <pdfaProperty:name>DOI</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The date when a publication was published.</pdfaProperty:description>
                           <pdfaProperty:name>MajorVersionDate</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://prismstandard.org/namespaces/basic/2.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>prism</pdfaSchema:prefix>
                  <pdfaSchema:schema>Prism</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The aggregation type specifies the unit of aggregation for a content collection. 
Comment 
PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. 
Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. 

</pdfaProperty:description>
                           <pdfaProperty:name>aggregationType</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.niso.org/schemas/jav/1.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>jav</pdfaSchema:prefix>
                  <pdfaSchema:schema>NISO</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Values for Journal Article Version are one of the following:
AO = Author’s Original
SMUR = Submitted Manuscript Under Review
AM = Accepted Manuscript
P = Proof
VoR = Version of Record
CVoR = Corrected Version of Record
EVoR = Enhanced Version of Record</pdfaProperty:description>
                           <pdfaProperty:name>journal_article_version</pdfaProperty:name>
                           <pdfaProperty:valueType>Closed Choice of Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
            </rdf:Bag>
         </pdfaExtension:schemas>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 508, 73, 538, 65
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 180, 65, 279, 57
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 508, 682, 540, 649
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 252, 671, 257, 658
       Flags: Print
       AppearanceDictionary: true
       Destination: 320
      Annotation: 
       Subtype: Link
       Rect: 262, 671, 267, 658
       Flags: Print
       AppearanceDictionary: true
       Destination: 320
      Annotation: 
       Subtype: Link
       Rect: 137, 647, 142, 634
       Flags: Print
       AppearanceDictionary: true
       Destination: 320
      Annotation: 
       Subtype: Link
       Rect: 91, 635, 96, 622
       Flags: Print
       AppearanceDictionary: true
       Destination: 320
      Annotation: 
       Subtype: Link
       Rect: 102, 635, 107, 622
       Flags: Print
       AppearanceDictionary: true
       Destination: 320
      Annotation: 
       Subtype: Link
       Rect: 59, 623, 64, 610
       Flags: Print
       AppearanceDictionary: true
       Destination: 320
      Annotation: 
       Subtype: Link
       Rect: 70, 623, 75, 610
       Flags: Print
       AppearanceDictionary: true
       Destination: 320
      Annotation: 
       Subtype: Link
       Rect: 98, 599, 103, 586
       Flags: Print
       AppearanceDictionary: true
       Destination: 320
      Annotation: 
       Subtype: Link
       Rect: 171, 599, 175, 586
       Flags: Print
       AppearanceDictionary: true
       Destination: 320
      Annotation: 
       Subtype: Link
       Rect: 207, 503, 217, 490
       Flags: Print
       AppearanceDictionary: true
       Destination: 320
      Annotation: 
       Subtype: Link
       Rect: 127, 455, 137, 442
       Flags: Print
       AppearanceDictionary: true
       Destination: 320
      Annotation: 
       Subtype: Link
       Rect: 260, 359, 270, 346
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 275, 359, 285, 346
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 214, 323, 224, 310
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 149, 263, 159, 250
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 164, 263, 174, 250
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 275, 239, 285, 226
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 231, 215, 240, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 246, 215, 256, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 139, 203, 149, 190
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 277, 203, 287, 190
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 236, 95, 246, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 118, 83, 128, 70
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 163, 83, 173, 70
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 228, 83, 238, 70
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 469, 671, 479, 658
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 523, 575, 533, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 481, 539, 491, 526
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
     Thumb: true
    Page: 
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 240, 587, 249, 574
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 93, 95, 103, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 202, 95, 212, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 375, 707, 385, 694
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 525, 707, 535, 694
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 440, 671, 450, 658
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 355, 563, 365, 550
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 334, 371, 344, 358
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 429, 371, 438, 358
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 307, 359, 317, 346
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 399, 83, 408, 70
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
     Thumb: true
    Page: 
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 59, 695, 69, 682
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 223, 695, 233, 682
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 233, 575, 243, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 211, 563, 221, 550
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 94, 503, 104, 490
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 153, 371, 163, 358
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 275, 371, 285, 358
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 129, 359, 139, 346
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 216, 359, 225, 346
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 84, 347, 94, 334
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 218, 335, 227, 322
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 90, 311, 100, 298
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 232, 311, 242, 298
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 122, 287, 131, 274
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 186, 263, 195, 250
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 307, 647, 317, 634
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 494, 467, 504, 454
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 330, 395, 340, 382
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
     Thumb: true
    Page: 
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 277, 611, 287, 598
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 232, 539, 242, 526
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 77, 95, 82, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 218
      Annotation: 
       Subtype: Link
       Rect: 470, 695, 475, 682
       Flags: Print
       AppearanceDictionary: true
       Destination: 218
      Annotation: 
       Subtype: Link
       Rect: 433, 515, 438, 502
       Flags: Print
       AppearanceDictionary: true
       Destination: 226
      Annotation: 
       Subtype: Link
       Rect: 381, 479, 385, 466
       Flags: Print
       AppearanceDictionary: true
       Destination: 226
      Annotation: 
       Subtype: Link
       Rect: 450, 239, 455, 226
       Flags: Print
       AppearanceDictionary: true
       Destination: 232
      Annotation: 
       Subtype: Link
       Rect: 401, 143, 406, 130
       Flags: Print
       AppearanceDictionary: true
       Destination: 232
      Annotation: 
       Subtype: Link
       Rect: 435, 71, 440, 58
       Flags: Print
       AppearanceDictionary: true
       Destination: 232
     Thumb: true
    Page: 
     Sequence: 6
     Thumb: true
    Page: 
     Sequence: 7
     Thumb: true
    Page: 
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 84, 263, 89, 250
       Flags: Print
       AppearanceDictionary: true
       Destination: 241
      Annotation: 
       Subtype: Link
       Rect: 133, 167, 138, 154
       Flags: Print
       AppearanceDictionary: true
       Destination: 241
      Annotation: 
       Subtype: Link
       Rect: 451, 275, 455, 262
       Flags: Print
       AppearanceDictionary: true
       Destination: 257
     Thumb: true
    Page: 
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 160, 251, 165, 238
       Flags: Print
       AppearanceDictionary: true
       Destination: 257
      Annotation: 
       Subtype: Link
       Rect: 59, 155, 69, 142
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 146, 155, 156, 142
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 135, 83, 144, 70
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 447, 275, 457, 262
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 307, 167, 317, 154
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 366, 131, 376, 118
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 511, 95, 521, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 486, 71, 496, 58
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
     Thumb: true
    Page: 
     Sequence: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 244, 251, 254, 238
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 147, 83, 157, 70
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 511, 695, 521, 682
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 440, 659, 450, 646
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 455, 659, 465, 646
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 510, 659, 519, 646
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 525, 659, 535, 646
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 389, 647, 398, 634
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 403, 647, 413, 634
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 473, 563, 483, 550
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 354, 395, 364, 382
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 490, 263, 495, 250
       Flags: Print
       AppearanceDictionary: true
       Destination: 320
      Annotation: 
       Subtype: Link
       Rect: 307, 203, 317, 190
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 329, 167, 339, 154
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 346, 167, 356, 154
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 330, 107, 340, 94
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
     Thumb: true
    Page: 
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 200, 575, 210, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 217, 575, 227, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 121, 563, 130, 550
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 128, 323, 138, 310
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 523, 563, 533, 550
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 477, 539, 487, 526
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 446, 527, 456, 514
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 307, 419, 317, 406
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 506, 323, 516, 310
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 423, 299, 433, 286
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 387, 239, 397, 226
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 364, 215, 373, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 307, 191, 317, 178
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 320, 167, 330, 154
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 389, 95, 399, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
     Thumb: true
    Page: 
     Sequence: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 233, 563, 243, 550
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 59, 515, 69, 502
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 123, 479, 133, 466
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 78, 431, 88, 418
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 152, 323, 162, 310
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 90, 239, 100, 226
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 275, 203, 285, 190
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 238, 179, 247, 166
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 260, 95, 270, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 275, 95, 285, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 503, 683, 513, 670
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 479, 611, 488, 598
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 327, 575, 337, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 331
      Annotation: 
       Subtype: Link
       Rect: 456, 551, 466, 538
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 471, 551, 481, 538
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 329, 527, 339, 514
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
      Annotation: 
       Subtype: Link
       Rect: 487, 503, 497, 490
       Flags: Print
       AppearanceDictionary: true
       Destination: 337
     Thumb: true
    Page: 
     Sequence: 13
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 248, 443, 287, 434
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 56, 434, 149, 425
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 470, 260, 538, 251
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 319, 251, 356, 242
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Sequence: 14
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 71, 243, 238, 234
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Sequence: 15
     Thumb: true
  Checksum: 1ce06086
   Type: CRC32
  Checksum: ea2bd8be2959f4e3b38631a4ee86290c
   Type: MD5
  Checksum: bcf0c815c91799ef208efc20875cb9f229a22f8a
   Type: SHA-1
  Checksum: 4bec86dab8aa11840b783cf387dd1500a87a30453912f22a7530f7f06f74a7cd
   Type: SHA-256