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found ID: PDF-HUL-149 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'alz70071-note-0001' cannot be found ID: PDF-HUL-122 Offset: 446431 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 544 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Validation of the CAMCOG-DS-II, a neuropsychological test battery for Alzheimer’s disease in people with Down syndrome: A Horizon 21 European Down syndrome Consortium study Destination: chapter..1 Children: Item: Title: Abstract Destination: section*.2 Item: Title: 1 | BACKGROUND Destination: section..1.1 Item: Title: 2 | METHODS Destination: section..1.2 Children: Item: Title: 2.1 | Development of the CAMCOG-DS-II Destination: subsection..1.2.1 Item: Title: 2.2 | Study design and participants Destination: subsection..1.2.2 Children: Item: Title: 2.2.1 | Inclusion criteria Destination: subsubsection..1.2.2.1 Item: Title: 2.2.2 | Exclusion criteria Destination: subsubsection..1.2.2.2 Item: Title: 2.3 | Neuropsychological tests Destination: subsection..1.2.3 Children: Item: Title: 2.3.1 | CAMCOG-DS-II Destination: subsubsection..1.2.3.1 Item: Title: 2.3.2 | CANTAB PAL Destination: subsubsection..1.2.3.2 Item: Title: 2.3.3 | mCRT Destination: subsubsection..1.2.3.3 Item: Title: 2.3.4 | Purdue Pegboard test Destination: subsubsection..1.2.3.4 Item: Title: 2.4 | AD classification Destination: subsection..1.2.4 Item: Title: 2.5 | Statistical analyses Destination: subsection..1.2.5 Item: Title: 3 | RESULTS Destination: section..1.3 Children: Item: Title: 3.1 | Psychometrics of the CAMCOG-DS-II and the comparator cognitive tests Destination: subsection..1.3.1 Children: Item: Title: 3.1.1 | Completion rates and floor and ceiling effects Destination: subsubsection..1.3.1.1 Item: Title: 3.1.2 | Construct validity Destination: subsubsection..1.3.1.2 Item: Title: 3.1.3 | Test-retest reliability Destination: subsubsection..1.3.1.3 Item: Title: 3.1.4 | Internal consistency reliability Destination: subsubsection..1.3.1.4 Item: Title: 3.1.5 | Test performance by clinical AD diagnosis Destination: subsubsection..1.3.1.5 Item: Title: 3.1.6 | Distinguishing AD participants from cognitively stable participants Destination: subsubsection..1.3.1.6 Item: Title: 3.1.7 | AD status following assessment Destination: subsubsection..1.3.1.7 Item: Title: 3.1.8 | Factors associated with performance on CAMCOG-DS-II total score and comparator cognitive tests Destination: subsubsection..1.3.1.8 Item: Title: 3.1.9 | Language-dependent variations in CAMCOG-DS-II total score and comparator cognitive test performance Destination: subsubsection..1.3.1.9 Item: Title: 4 | DISCUSSION Destination: section..1.4 Children: Item: Title: 4.1 | Diagnosing AD in people with DS Destination: subsection..1.4.1 Item: Title: 4.2 | Floor and ceiling effects Destination: subsection..1.4.2 Item: Title: 4.3 | Factors associated with performance Destination: subsection..1.4.3 Item: Title: 4.4 | Language effects Destination: subsection..1.4.4 Item: Title: 4.5 | Strengths and limitations Destination: subsection..1.4.5 Item: Title: 5 | FUTURE DIRECTIONS Destination: section..1.5 Item: Title: 6 | CONCLUSIONS Destination: section..1.6 Item: Title: ACKNOWLEDGMENTS Destination: section*.4 Item: Title: CONFLICT OF INTEREST STATEMENT Destination: section*.6 Item: Title: CONSENT STATEMENT Destination: section*.8 Item: Title: DIVERSITY, EQUITY, AND INCLUSION STATEMENT Destination: section*.10 Item: Title: STUDY DESIGN AND RECRUITMENT Destination: section*.12 Item: Title: ACCOMMODATIONS AND SUPPORT Destination: section*.14 Item: Title: DATA INTERPRETATION Destination: section*.16 Item: Title: ORCID Destination: section*.18 Item: Title: REFERENCES Destination: section*.20 Item: Title: SUPPORTING INFORMATION Destination: section*.22 Info: Title: Validation of the CAMCOG‐DS‐II, a 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