189b2c34ed78e93592bd99f745c1d807  comstrbiojou_a2025v28p281iENG.pdf
8a6933eda209529e0fc2ec29377970fb0dc01992  comstrbiojou_a2025v28p281iENG.pdf
1664bc38de02328090a839d957162b91db9427b98b6e0065d963594424e772be  comstrbiojou_a2025v28p281iENG.pdf

Title:           An artificial intelligence-based platform for personalized predictions of Metacognitive Training effectiveness
Subject:         Computational and Structural Biotechnology Journal, 28 (2025) 281-293. doi:10.1016/j.csbj.2025.07.051
Keywords:        Personalized medicine,Explainable artificial intelligence,Feature selection,Fairness,Metacognitive Training,Mental health
Author:          Caroline König
Creator:         Elsevier
Producer:        Acrobat Distiller 8.1.0 (Windows)
CreationDate:    Sat Aug  9 23:04:35 2025 CEST
ModDate:         Mon Aug 11 10:48:22 2025 CEST
Custom Metadata: yes
Metadata Stream: yes
Tagged:          yes
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           13
Encrypted:       no
Page size:       595.276 x 793.701 pts
Page rot:        0
File size:       2073765 bytes
Optimized:       yes
PDF version:     1.7


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
BALPOI+charssil-Bold                 Type 1C           Custom           yes yes yes   2494  0
BALPNG+charssil-Italic               Type 1C           Custom           yes yes yes   2499  0
BALPIG+STIXMath-Regular              Type 1C           Custom           yes yes yes   2504  0
BALPIH+STIXMath-Italic               Type 1C           Custom           yes yes yes   2509  0
BALPGE+charssil                      Type 1C           Custom           yes yes yes   2514  0
BALPGG+Univers                       Type 1C           WinAnsi          yes yes no    2519  0
BALPNH+CharisSIL                     Type 1C           Custom           yes yes yes   2522  0
AAAXTD+CharisSIL                     CID TrueType      Identity-H       yes yes yes   2527  0
MIWDJM+CharisSIL                     CID TrueType      Identity-H       yes yes yes   2535  0
BALPGF+Helvetica                     Type 1C           WinAnsi          yes yes no    2541  0
AAAAME+CharisSIL-Italic              CID TrueType      Identity-H       yes yes yes    349  0
AAAAAD+CharisSIL                     CID TrueType      Identity-H       yes yes yes    356  0
ZXVKJS+CharisSIL-Italic              CID TrueType      Identity-H       yes yes yes    363  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2025-10-29 04:37:23 CET
 RepresentationInformation: comstrbiojou_a2025v28p281iENG.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2025-10-28 14:46:47 CET
  Size: 2073765
  Format: PDF
  Version: 1.7
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 2624
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    ViewerPreferences: 
     HideToolbar: false
     HideMenubar: false
     HideWindowUI: false
     FitWindow: false
     CenterWindow: false
     DisplayDocTitle: true
     NonFullScreenPageMode: UseNone
     Direction: L2R
     ViewArea: CropBox
     ViewClip: CropBox
     PrintArea: CropBox
     PageClip: CropBox
    PageLayout: SinglePage
    PageMode: UseOutlines
    Language: en
    Outlines: 
     Item: 
      Title: An artificial intelligence-based platform for personalized predictions of Metacognitive Training effectiveness
      Destination: csbj3253.title.0:1
      Children: 
       Item: 
        Title: 1 Introduction
        Destination: csbj3253.section.1:2
       Item: 
        Title: 2 Materials
        Destination: csbj3253.section.2:3
       Item: 
        Title: 3 Methods
        Destination: csbj3253.section.3:4
        Children: 
         Item: 
          Title: 3.1 Analysis of requirements
          Destination: csbj3253.subsection.1:6
          Children: 
           Item: 
            Title: 3.1.1 Definition of prediction targets
            Destination: csbj3253.subsubsection.1:7
           Item: 
            Title: 3.1.2 System design
            Destination: csbj3253.subsubsection.2:10
         Item: 
          Title: 3.2 Development of ML models
          Destination: csbj3253.subsection.2:11
          Children: 
           Item: 
            Title: 3.2.1 Feature selection
            Destination: csbj3253.subsubsection.1:12
           Item: 
            Title: 3.2.2 Predictive models
            Destination: csbj3253.subsubsection.2:13
           Item: 
            Title: 3.2.3 Model explanations
            Destination: csbj3253.subsubsection.3:14
         Item: 
          Title: 3.3 Fairness
          Destination: csbj3253.subsection.3:15
       Item: 
        Title: 4 Results
        Destination: csbj3253.section.4:16
        Children: 
         Item: 
          Title: 4.1 Feature selection
          Destination: csbj3253.subsection.1:17
         Item: 
          Title: 4.2 Definition of baseline variables
          Destination: csbj3253.subsection.2:19
         Item: 
          Title: 4.3 Predictive models
          Destination: csbj3253.subsection.3:21
         Item: 
          Title: 4.4 Web-based predictive platform
          Destination: csbj3253.subsection.4:25
         Item: 
          Title: 4.5 Ethical concerns
          Destination: csbj3253.subsection.5:26
          Children: 
           Item: 
            Title: 4.5.1 Transparency and explainability
            Destination: csbj3253.subsubsection.1:27
           Item: 
            Title: 4.5.2 Data privacy and security
            Destination: csbj3253.subsubsection.2:29
           Item: 
            Title: 4.5.3 Gender bias analysis
            Destination: csbj3253.subsubsection.3:30
           Item: 
            Title: 4.5.4 Regulatory compliance
            Destination: csbj3253.subsubsection.4:32
           Item: 
            Title: 4.5.5 Clinical applicability
            Destination: csbj3253.subsubsection.5:33
         Item: 
          Title: 4.6 MCT personalization
          Destination: csbj3253.subsection.6:34
          Children: 
           Item: 
            Title: 4.6.1 Present functional design
            Destination: csbj3253.subsubsection.1:35
           Item: 
            Title: 4.6.2 Challenges and strategic improvements
            Destination: csbj3253.subsubsection.2:36
       Item: 
        Title: 5 Discussion and conclusions
        Destination: csbj3253.section.5:37
       Item: 
        Title: CRediT authorship contribution statement
        Destination: csbj3253.section.5:38
       Item: 
        Title: Funding
        Destination: csbj3253.section.5:39
       Item: 
        Title: Declaration of competing interest
        Destination: csbj3253.section.5:40
       Item: 
        Title: Acknowledgements
        Destination: csbj3253.section.5:41
       Item: 
        Title: Appendix A Supplementary material
        Destination: csbj3253.appendix.1:42
       Item: 
        Title: References
        Destination: csbj3253.section.5:44
   Info: 
    Title: An artificial intelligence-based platform for personalized predictions of Metacognitive Training effectiveness
    Author: Caroline König
    Subject: Computational and Structural Biotechnology Journal, 28 (2025) 281-293. doi:10.1016/j.csbj.2025.07.051
    Keywords: Personalized medicine,Explainable artificial intelligence,Feature selection,Fairness,Metacognitive Training,Mental health
    Creator: Elsevier
    Producer: Acrobat Distiller 8.1.0 (Windows)
    CreationDate: Sat Aug 09 23:04:35 CEST 2025
    ModDate: Mon Aug 11 10:48:22 CEST 2025
   ID: 0xf854371f5d5a482dc8340434e70d439a, 0x3951249785f9b6d1d9ee5b8d9fd73665
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 246
      ImageHeight: 271
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 237
      ImageHeight: 298
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1557
      ImageHeight: 458
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1561
      ImageHeight: 812
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1559
      ImageHeight: 1003
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1557
      ImageHeight: 701
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1561
      ImageHeight: 1606
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1038
      ImageHeight: 958
      BitsPerSample: 8
      BitsPerSampleUnit: integer
   Fonts: 
    Type0: 
     Font: 
      BaseFont: AAAAAD+CharisSIL
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: MIWDJM+CharisSIL
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: ZXVKJS+CharisSIL-Italic
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: AAAAME+CharisSIL-Italic
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: AAAXTD+CharisSIL
      Encoding: Identity-H
      ToUnicode: true
    Type1: 
     Font: 
      BaseFont: BALPGE+charssil
      FontSubset: true
      FirstChar: 2
      LastChar: 252
      FontDescriptor: 
       FontName: BALPGE+charssil
       Flags: Serif, Symbolic
       FontBBox: -79, -229, 1000, 928
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: BALPNG+charssil-Italic
      FontSubset: true
      FirstChar: 40
      LastChar: 252
      FontDescriptor: 
       FontName: BALPNG+charssil-Italic
       Flags: Serif, Symbolic, Italic
       FontBBox: -130, -229, 1000, 927
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: BALPGG+Univers
      FontSubset: true
      FirstChar: 46
      LastChar: 119
      FontDescriptor: 
       FontName: BALPGG+Univers
       Flags: Nonsymbolic
       FontBBox: -168, -250, 992, 947
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: BALPIG+STIXMath-Regular
      FontSubset: true
      FirstChar: 2
      LastChar: 177
      FontDescriptor: 
       FontName: BALPIG+STIXMath-Regular
       Flags: Serif, Symbolic
       FontBBox: -970, -341, 1096, 1023
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: BALPNH+CharisSIL
      FontSubset: true
      FirstChar: 65
      LastChar: 84
      FontDescriptor: 
       FontName: BALPNH+CharisSIL
       Flags: Serif, Symbolic
       FontBBox: 4, -16, 692, 687
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: BALPGF+Helvetica
      FontSubset: true
      FirstChar: 32
      LastChar: 32
      FontDescriptor: 
       FontName: BALPGF+Helvetica
       Flags: Nonsymbolic
       FontBBox: -166, -225, 1000, 931
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: BALPIH+STIXMath-Italic
      FontSubset: true
      FirstChar: 2
      LastChar: 46
      FontDescriptor: 
       FontName: BALPIH+STIXMath-Italic
       Flags: Symbolic, Italic
       FontBBox: 19, -187, 1055, 668
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: BALPOI+charssil-Bold
      FontSubset: true
      FirstChar: 2
      LastChar: 246
      FontDescriptor: 
       FontName: BALPOI+charssil-Bold
       Flags: Serif, Symbolic, ForceBold
       FontBBox: 0, -231, 878, 929
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
    CIDFontType2: 
     Font: 
      BaseFont: AAAXTD+CharisSIL
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: AAAXTD+CharisSIL
       Flags: Symbolic
       FontBBox: -692, -533, 1623, 1318
       FontFile2: true
     Font: 
      BaseFont: AAAAAD+CharisSIL
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: AAAAAD+CharisSIL
       Flags: Symbolic
       FontBBox: -692, -533, 1623, 1318
       FontFile2: true
     Font: 
      BaseFont: MIWDJM+CharisSIL
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: MIWDJM+CharisSIL
       Flags: Serif, Symbolic
       FontBBox: -692, -533, 1623, 1319
       FontFile2: true
     Font: 
      BaseFont: ZXVKJS+CharisSIL-Italic
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: ZXVKJS+CharisSIL-Italic
       Flags: Serif, Symbolic, Italic
       FontBBox: -716, -533, 1627, 1318
       FontFile2: true
     Font: 
      BaseFont: AAAAME+CharisSIL-Italic
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: AAAAME+CharisSIL-Italic
       Flags: Symbolic, Italic
       FontBBox: -716, -533, 1626, 1317
       FontFile2: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="XMP Core 5.1.2">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:ali="http://www.niso.org/schemas/ali/1.0/">
         <ali:license_ref>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <ali:uri>http://creativecommons.org/licenses/by-nc-nd/4.0/</ali:uri>
               </rdf:li>
            </rdf:Bag>
         </ali:license_ref>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:crossmark="http://crossref.org/crossmark/1.0/">
         <crossmark:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>elsevier.com</rdf:li>
               <rdf:li>sciencedirect.com</rdf:li>
            </rdf:Seq>
         </crossmark:CrossMarkDomains>
         <crossmark:CrossmarkDomainExclusive>true</crossmark:CrossmarkDomainExclusive>
         <crossmark:DOI>10.1016/j.csbj.2025.07.051</crossmark:DOI>
         <crossmark:MajorVersionDate>2010-04-23</crossmark:MajorVersionDate>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>10.1016/j.csbj.2025.07.051</dc:identifier>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Elsevier B.V.</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Computational and Structural Biotechnology Journal, 28 (2025) 281-293. doi:10.1016/j.csbj.2025.07.051</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>Personalized medicine</rdf:li>
               <rdf:li>Explainable artificial intelligence</rdf:li>
               <rdf:li>Feature selection</rdf:li>
               <rdf:li>Fairness</rdf:li>
               <rdf:li>Metacognitive Training</rdf:li>
               <rdf:li>Mental health</rdf:li>
            </rdf:Bag>
         </dc:subject>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">An artificial intelligence-based platform for personalized predictions of Metacognitive Training effectiveness</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Caroline König</rdf:li>
               <rdf:li>Pedro Copado</rdf:li>
               <rdf:li>Alfredo Vellido</rdf:li>
               <rdf:li>Àngela Nebot</rdf:li>
               <rdf:li>Cecilio Angulo</rdf:li>
               <rdf:li>Maria Lamarca</rdf:li>
               <rdf:li>Vanessa Acuña</rdf:li>
               <rdf:li>Fabrice Berna</rdf:li>
               <rdf:li>Steffen Moritz</rdf:li>
               <rdf:li>Łukasz Gawęda</rdf:li>
               <rdf:li>Susana Ochoa</rdf:li>
            </rdf:Seq>
         </dc:creator>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:jav="http://www.niso.org/schemas/jav/1.0/">
         <jav:journal_article_version>VoR</jav:journal_article_version>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:CreationDate--Text>11th August 2025</pdf:CreationDate--Text>
         <pdf:Producer>Acrobat Distiller 8.1.0 (Windows)</pdf:Producer>
         <pdf:Keywords>Personalized medicine,Explainable artificial intelligence,Feature selection,Fairness,Metacognitive Training,Mental health</pdf:Keywords>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/">
         <pdfx:CreationDate--Text>11th August 2025</pdfx:CreationDate--Text>
         <pdfx:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>sciencedirect.com</rdf:li>
               <rdf:li>elsevier.com</rdf:li>
            </rdf:Seq>
         </pdfx:CrossMarkDomains>
         <pdfx:CrossmarkDomainExclusive>true</pdfx:CrossmarkDomainExclusive>
         <pdfx:CrossmarkMajorVersionDate>2010-04-23</pdfx:CrossmarkMajorVersionDate>
         <pdfx:ElsevierWebPDFSpecifications>7.0.1</pdfx:ElsevierWebPDFSpecifications>
         <pdfx:doi>10.1016/j.csbj.2025.07.051</pdfx:doi>
         <pdfx:robots>noindex</pdfx:robots>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:prism="http://prismstandard.org/namespaces/basic/3.0/">
         <prism:aggregationType>journal</prism:aggregationType>
         <prism:copyright>© 2025 The Author(s). Published by Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology.</prism:copyright>
         <prism:coverDate>2025-01-01</prism:coverDate>
         <prism:coverDisplayDate>11 August 2025</prism:coverDisplayDate>
         <prism:doi>10.1016/j.csbj.2025.07.051</prism:doi>
         <prism:endingPage>293</prism:endingPage>
         <prism:issn>2001-0370</prism:issn>
         <prism:pageRange>281-293</prism:pageRange>
         <prism:publicationName>Computational and Structural Biotechnology Journal</prism:publicationName>
         <prism:startingPage>281</prism:startingPage>
         <prism:url>https://doi.org/10.1016/j.csbj.2025.07.051</prism:url>
         <prism:volume>28</prism:volume>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:tdm="http://www.w3.org/ns/tdmrep/">
         <tdm:policy>https://www.elsevier.com/tdm/tdmrep-policy.json</tdm:policy>
         <tdm:reservation>1</tdm:reservation>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:CreateDate>2025-08-09T21:04:35</xmp:CreateDate>
         <xmp:CreatorTool>Elsevier</xmp:CreatorTool>
         <xmp:MetadataDate>2025-08-11T08:48:22</xmp:MetadataDate>
         <xmp:ModifyDate>2025-08-11T08:48:22</xmp:ModifyDate>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <xmpMM:DocumentID>uuid:1b499bed-4ce8-4c0c-b682-0d58baae1cbe</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:b6ed5266-03cb-4855-90c0-636283357f42</xmpMM:InstanceID>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpRights="http://ns.adobe.com/xap/1.0/rights/">
         <xmpRights:Marked>True</xmpRights:Marked>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 281
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Contents: URI link to http://www.ScienceDirect.com/
       Rect: 329, 730, 377, 738
      Annotation: 
       Subtype: Link
       Contents: URI link to http://www.elsevier.com/locate/csbj
       Rect: 288, 675, 400, 683
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel10.label
       Rect: 116, 590, 121, 599
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: URI link to http://orcid.org/0000-0002-7543-8686
       Rect: 122, 590, 132, 599
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cor1thanks.label
       Rect: 132, 590, 138, 599
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel10.label
       Rect: 210, 590, 215, 599
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: URI link to http://orcid.org/0000-0003-4219-5056
       Rect: 216, 590, 226, 599
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel10.label
       Rect: 304, 590, 309, 599
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel10.label
       Rect: 380, 590, 384, 599
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: URI link to http://orcid.org/0000-0002-4621-8262
       Rect: 385, 590, 395, 599
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel20.label
       Rect: 471, 590, 476, 599
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel30.label
       Rect: 117, 573, 121, 583
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel40.label
       Rect: 122, 573, 127, 583
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel50.label
       Rect: 128, 573, 132, 583
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: URI link to http://orcid.org/0009-0009-6426-560X
       Rect: 133, 573, 143, 583
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel70.label
       Rect: 220, 573, 225, 583
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel80.label
       Rect: 297, 573, 302, 583
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel90.label
       Rect: 375, 573, 380, 583
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel100.label
       Rect: 460, 573, 463, 583
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel30.label
       Rect: 112, 561, 116, 570
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: Link to named destination addresslabel40.label
       Rect: 117, 561, 122, 570
       Destination: 2477
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.zhang2018learning
       Rect: 48, 197, 53, 204
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.egger2022medical
       Rect: 55, 197, 60, 204
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: URI link to mailto:caroline.leonore.konig@upc.edu
       Rect: 106, 114, 209, 121
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.fusar2016predicting
       Rect: 317, 251, 322, 258
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.dwyer2018machine
       Rect: 324, 251, 329, 258
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.stumpp2022evidence
       Rect: 428, 230, 434, 237
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.fisher2015toward
       Rect: 317, 198, 322, 205
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.arias2022quantifying
       Rect: 512, 166, 518, 173
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.Mancuso2014
       Rect: 535, 155, 541, 162
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: URI link to https://doi.org/10.1016/j.csbj.2025.07.051
       Rect: 46, 97, 185, 104
      Annotation: 
       Subtype: Link
       Rect: 181, 748, 413, 760
      Annotation: 
       Subtype: Link
       Rect: 501, 616, 529, 644
      Annotation: 
       Subtype: Link
       Rect: 165, 48, 331, 59
    Page: 
     Label: 282
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.pares2014cost
       Rect: 179, 729, 185, 736
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.morrison2014cognitive
       Rect: 48, 687, 58, 694
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.Moritz2016
       Rect: 270, 687, 280, 694
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.moritz2023metacognitive
       Rect: 281, 687, 291, 694
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.schlechte2025metakognitives
       Rect: 48, 656, 58, 663
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.lamarca2024reducing
       Rect: 281, 624, 291, 631
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.meinhart2025metacognitive
       Rect: 209, 614, 219, 621
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.acuna2022efficacy
       Rect: 72, 593, 82, 600
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.acuna2024assessing
       Rect: 178, 593, 188, 600
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.salas2020gender
       Rect: 105, 562, 114, 569
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.moritz2018moderators
       Rect: 261, 551, 271, 558
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.gonzalez2021moderators
       Rect: 274, 551, 284, 558
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: URI link to https://www.permepsy.org
       Rect: 223, 498, 291, 506
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.Moritz2007
       Rect: 181, 279, 191, 286
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.ai_act_2024
       Rect: 221, 112, 231, 119
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.busch2024navigating
       Rect: 357, 687, 366, 694
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.Lisboaetal23
       Rect: 317, 644, 327, 651
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.burkart2021survey
       Rect: 328, 644, 338, 651
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.ribeiro2016should
       Rect: 482, 613, 492, 620
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.lundberg2017unified
       Rect: 409, 602, 418, 609
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.FRA2018
       Rect: 387, 528, 397, 535
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.mehrabi2021survey
       Rect: 365, 475, 375, 482
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.cirillo2020sex
       Rect: 481, 444, 491, 451
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.feldman2015certifying
       Rect: 495, 380, 505, 387
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination mat.label
       Rect: 451, 305, 455, 313
       Destination: 1
      Annotation: 
       Subtype: Link
       Contents: Link to named destination meth.label
       Rect: 363, 295, 368, 303
       Destination: 33
      Annotation: 
       Subtype: Link
       Contents: Link to named destination results.label
       Rect: 492, 295, 496, 303
       Destination: 62
      Annotation: 
       Subtype: Link
       Contents: Link to named destination disc.label
       Rect: 537, 274, 541, 282
       Destination: 136
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.konig2025data
       Rect: 317, 207, 327, 214
       Destination: 220
    Page: 
     Label: 283
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.konig2025data
       Rect: 239, 548, 249, 555
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.konig2024group
       Rect: 246, 516, 256, 523
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.kim2024comprehensive
       Rect: 48, 464, 58, 471
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.chow2023ilhbn
       Rect: 281, 402, 291, 409
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.maale2024effects
       Rect: 89, 329, 99, 336
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination fig1.label
       Rect: 274, 266, 279, 274
       Destination: 33
      Annotation: 
       Subtype: Link
       Contents: Link to named destination fig6.label
       Rect: 387, 475, 392, 483
       Destination: 51
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.konig2025data
       Rect: 480, 465, 490, 472
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.Kay1987
       Rect: 477, 403, 487, 410
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.haddock1999scales
       Rect: 542, 382, 552, 389
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.rosenberg1965rosenberg
       Rect: 475, 340, 485, 347
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.beck2004new
       Rect: 465, 320, 475, 326
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.beck2004new
       Rect: 394, 59, 404, 66
       Destination: 220
    Page: 
     Label: 284
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Contents: Link to named destination fig7.label
       Rect: 74, 80, 79, 88
       Destination: 51
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.scikit-learn
       Rect: 512, 245, 521, 252
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.django
       Rect: 485, 193, 495, 200
       Destination: 220
    Page: 
     Label: 285
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.naidu2023review
       Rect: 258, 654, 268, 661
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.chicco2020advantages
       Rect: 87, 590, 97, 597
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.breiman2001random
       Rect: 60, 426, 70, 433
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.altmann-2010
       Rect: 238, 405, 248, 412
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.ke2017lightgbm
       Rect: 118, 316, 128, 322
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.friedman2001greedy
       Rect: 73, 305, 83, 312
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.sutton2005classification
       Rect: 98, 262, 108, 269
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.bertsimas2017logistic
       Rect: 104, 230, 114, 237
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.chawla2002smote
       Rect: 150, 198, 160, 205
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.vstrumbelj2014explaining
       Rect: 382, 729, 392, 736
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.shapley1953value
       Rect: 344, 719, 354, 726
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.lundberg2020local2global
       Rect: 537, 645, 547, 652
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.ai_act_2024
       Rect: 500, 593, 510, 600
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.feldman2015certifying
       Rect: 446, 573, 456, 580
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.CFR1607
       Rect: 542, 552, 552, 559
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.wisniewski2022fairmodels
       Rect: 385, 489, 395, 496
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.CFR1607
       Rect: 399, 447, 409, 454
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination subeq12.label
       Rect: 364, 351, 369, 359
       Destination: 62
      Annotation: 
       Subtype: Link
       Contents: Link to named destination subeq13.label
       Rect: 392, 351, 396, 359
       Destination: 62
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.latif2023ai
       Rect: 398, 268, 408, 275
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.mowery2011paired
       Rect: 410, 268, 420, 275
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.salas2020gender
       Rect: 473, 226, 483, 233
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination fig2.label
       Rect: 440, 121, 444, 129
       Destination: 89
    Page: 
     Label: 286
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.konig2025data
       Rect: 238, 280, 248, 287
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination tab1.label
       Rect: 349, 195, 354, 203
       Destination: 89
      Annotation: 
       Subtype: Link
       Contents: Link to named destination tab1.label
       Rect: 460, 121, 465, 129
       Destination: 89
      Annotation: 
       Subtype: Link
       Contents: Link to named destination tab8.label
       Rect: 383, 58, 387, 66
       Destination: 98
    Page: 
     Label: 287
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Contents: Link to named destination tab2.label
       Rect: 80, 195, 85, 203
       Destination: 105
      Annotation: 
       Subtype: Link
       Contents: Link to named destination fig3.label
       Rect: 484, 188, 489, 196
       Destination: 98
    Page: 
     Label: 288
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Contents: Link to named destination fig4.label
       Rect: 75, 174, 79, 182
       Destination: 105
      Annotation: 
       Subtype: Link
       Contents: Link to named destination fig4.label
       Rect: 148, 90, 152, 98
       Destination: 105
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.mydisk_upc
       Rect: 507, 266, 517, 273
       Destination: 220
    Page: 
     Label: 289
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Contents: Link to named destination tab3.label
       Rect: 237, 520, 241, 528
       Destination: 113
      Annotation: 
       Subtype: Link
       Contents: Link to named destination tab3.label
       Rect: 200, 478, 205, 486
       Destination: 113
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.eke2025role
       Rect: 469, 374, 479, 381
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.okwor2024digital
       Rect: 329, 301, 339, 308
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.gaube2021ai
       Rect: 329, 91, 339, 98
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.vasconcelos2023explanations
       Rect: 317, 59, 327, 66
       Destination: 220
    Page: 
     Label: 290
     Sequence: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.tenea2025
       Rect: 486, 593, 496, 600
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.pederson_2018
       Rect: 504, 520, 514, 527
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.frost2017integrated
       Rect: 486, 488, 496, 495
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.WHODAS2010
       Rect: 474, 447, 484, 454
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.Morosini2000
       Rect: 427, 436, 437, 443
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.watson2022cognitive
       Rect: 403, 279, 413, 286
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.vita2022european
       Rect: 429, 227, 439, 234
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.horvath2011alliance
       Rect: 358, 112, 368, 119
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.stefana2024patients
       Rect: 369, 112, 379, 119
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.horvath1989development
       Rect: 379, 80, 389, 87
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.duncan2003session
       Rect: 513, 80, 523, 87
       Destination: 220
    Page: 
     Label: 291
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.bartholomew2021therapists
       Rect: 117, 739, 127, 746
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.kappen2018evaluating
       Rect: 225, 666, 235, 673
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.pennestri2025sharing
       Rect: 88, 624, 98, 631
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.ISO16290
       Rect: 191, 216, 201, 223
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination legis.label
       Rect: 104, 194, 121, 202
       Destination: 113
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.busch2024navigating
       Rect: 227, 175, 237, 182
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.salas2020gender
       Rect: 511, 520, 521, 527
       Destination: 149
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.FRA2018
       Rect: 542, 467, 552, 474
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination cite.chow2023ilhbn
       Rect: 327, 227, 337, 234
       Destination: 220
      Annotation: 
       Subtype: Link
       Contents: Link to named destination lim.label
       Rect: 332, 100, 350, 108
       Destination: 122
    Page: 
     Label: 292
     Sequence: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Contents: Link to named destination clin_app.label
       Rect: 214, 707, 232, 715
       Destination: 113
      Annotation: 
       Subtype: Link
       Contents: URI link to https://doi.org/10.1016/j.csbj.2025.07.051
       Rect: 315, 707, 470, 715
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib0DD67348B56589B8B6EAD827BAF32268s1
       Rect: 330, 668, 565, 673
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib0DD67348B56589B8B6EAD827BAF32268s1
       Rect: 330, 659, 565, 664
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib0DD67348B56589B8B6EAD827BAF32268s1
       Rect: 330, 651, 381, 656
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibE584E13D3A3F32E16FD7D4324E93F2AAs1
       Rect: 330, 642, 565, 647
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibE584E13D3A3F32E16FD7D4324E93F2AAs1
       Rect: 330, 634, 565, 639
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibE584E13D3A3F32E16FD7D4324E93F2AAs1
       Rect: 330, 625, 382, 630
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3CF8ADA29302877937C7CB8742851985s1
       Rect: 330, 617, 565, 622
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3CF8ADA29302877937C7CB8742851985s1
       Rect: 330, 608, 565, 613
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3CF8ADA29302877937C7CB8742851985s1
       Rect: 330, 599, 371, 604
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib8A92074856AF7DA9EA9FDBBF857699CAs1
       Rect: 330, 591, 565, 596
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib8A92074856AF7DA9EA9FDBBF857699CAs1
       Rect: 330, 582, 514, 587
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibFFED3DF8DC0525F0FDF256C10025AA32s1
       Rect: 330, 574, 565, 579
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibFFED3DF8DC0525F0FDF256C10025AA32s1
       Rect: 330, 565, 458, 570
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib565A42FFE6CE3EC84B2D0DD5CB63C053s1
       Rect: 330, 557, 565, 562
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib565A42FFE6CE3EC84B2D0DD5CB63C053s1
       Rect: 330, 548, 486, 553
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibECF27C373FAF8AE472AAF9D7FCD33B87s1
       Rect: 330, 539, 565, 544
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibECF27C373FAF8AE472AAF9D7FCD33B87s1
       Rect: 330, 531, 471, 536
      Annotation: 
       Subtype: Link
       Contents: URI link to https://doi.org/10.1093/eurpub/cku166.129
       Rect: 411, 504, 539, 511
      Annotation: 
       Subtype: Link
       Contents: URI link to https://doi.org/10.1371/journal.pone.0105471
       Rect: 511, 487, 566, 493
      Annotation: 
       Subtype: Link
       Contents: URI link to https://doi.org/10.1371/journal.pone.0105471
       Rect: 330, 478, 410, 485
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3AF36FC3FC15889A538AA631651BA7D7s1
       Rect: 330, 471, 565, 476
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3AF36FC3FC15889A538AA631651BA7D7s1
       Rect: 330, 462, 565, 467
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3AF36FC3FC15889A538AA631651BA7D7s1
       Rect: 330, 454, 524, 459
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib4117FA36FD4071632FC588216014AF5As1
       Rect: 330, 445, 565, 450
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib4117FA36FD4071632FC588216014AF5As1
       Rect: 330, 437, 438, 442
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib56B31C631E7C9BE27C73ABD6634D7D21s1
       Rect: 330, 428, 565, 433
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib56B31C631E7C9BE27C73ABD6634D7D21s1
       Rect: 330, 419, 565, 424
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibE1D02BA61B9B115FEC36A7C1FF201A1Ds1
       Rect: 330, 411, 565, 416
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibE1D02BA61B9B115FEC36A7C1FF201A1Ds1
       Rect: 330, 402, 441, 407
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib7835DD502251D2344C81C66E91A9CFE3s1
       Rect: 330, 394, 565, 399
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib7835DD502251D2344C81C66E91A9CFE3s1
       Rect: 330, 385, 565, 390
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib7835DD502251D2344C81C66E91A9CFE3s1
       Rect: 330, 377, 460, 382
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib6A6551B464B38142D3BFA7777F85D4A4s1
       Rect: 330, 368, 565, 373
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib6A6551B464B38142D3BFA7777F85D4A4s1
       Rect: 330, 359, 565, 364
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib6A6551B464B38142D3BFA7777F85D4A4s1
       Rect: 330, 351, 367, 356
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibA29DA970A88D8DC973454653EC0D80A8s1
       Rect: 330, 342, 565, 347
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibA29DA970A88D8DC973454653EC0D80A8s1
       Rect: 330, 334, 565, 339
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibA29DA970A88D8DC973454653EC0D80A8s1
       Rect: 330, 325, 374, 330
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib81831271FAF6D646F8ED5CD5961A5058s1
       Rect: 330, 317, 565, 323
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib81831271FAF6D646F8ED5CD5961A5058s1
       Rect: 330, 308, 565, 313
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib81831271FAF6D646F8ED5CD5961A5058s1
       Rect: 330, 299, 519, 304
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibB7788047242BE292CFDBC60067BEBE89s1
       Rect: 330, 291, 565, 296
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibB7788047242BE292CFDBC60067BEBE89s1
       Rect: 330, 282, 565, 287
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibB7788047242BE292CFDBC60067BEBE89s1
       Rect: 330, 274, 463, 279
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib5C867AD427CD65CCA7693D16CECD84CAs1
       Rect: 330, 265, 565, 270
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib5C867AD427CD65CCA7693D16CECD84CAs1
       Rect: 330, 257, 565, 262
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib5C867AD427CD65CCA7693D16CECD84CAs1
       Rect: 330, 248, 460, 253
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib57BC4CC66605209535A873F9D7BF9284s1
       Rect: 330, 239, 565, 244
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib57BC4CC66605209535A873F9D7BF9284s1
       Rect: 330, 231, 565, 236
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib57BC4CC66605209535A873F9D7BF9284s1
       Rect: 330, 222, 422, 227
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib0EBF4A2562BC5D60C742235CA1E3955As1
       Rect: 330, 214, 565, 219
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib0EBF4A2562BC5D60C742235CA1E3955As1
       Rect: 330, 205, 565, 210
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib0EBF4A2562BC5D60C742235CA1E3955As1
       Rect: 330, 197, 447, 202
      Annotation: 
       Subtype: Link
       Contents: URI link to https://doi.org/10.1097/YCO.0b013e3282f0b8ed
       Rect: 380, 170, 521, 176
      Annotation: 
       Subtype: Link
       Contents: URI link to https://www.europarl.europa.eu/doceo/document/TA-9-2024-0138_EN.pdf
       Rect: 450, 161, 566, 168
      Annotation: 
       Subtype: Link
       Contents: URI link to https://www.europarl.europa.eu/doceo/document/TA-9-2024-0138_EN.pdf
       Rect: 330, 153, 430, 159
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibC3224843EBB35F172507E31F3665BCABs1
       Rect: 330, 137, 565, 142
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibC3224843EBB35F172507E31F3665BCABs1
       Rect: 330, 128, 537, 133
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib11130ABD51439E9735C8312069C2E5F8s1
       Rect: 330, 119, 565, 124
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib11130ABD51439E9735C8312069C2E5F8s1
       Rect: 330, 111, 565, 116
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib11130ABD51439E9735C8312069C2E5F8s1
       Rect: 330, 102, 378, 107
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib2F4B4B9F7AD9A5ED2EE0383C5EBE4F9Bs1
       Rect: 330, 94, 565, 99
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib2F4B4B9F7AD9A5ED2EE0383C5EBE4F9Bs1
       Rect: 330, 85, 430, 90
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib73A4F1A4390B6D7C4F0C164DC1248DEEs1
       Rect: 330, 77, 565, 82
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib73A4F1A4390B6D7C4F0C164DC1248DEEs1
       Rect: 330, 68, 565, 73
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib73A4F1A4390B6D7C4F0C164DC1248DEEs1
       Rect: 330, 59, 502, 64
    Page: 
     Label: 293
     Sequence: 13
     Annotations: 
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib4F3CC052382D7A93F8E8BE02E7F84F67s1
       Rect: 61, 739, 296, 744
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib4F3CC052382D7A93F8E8BE02E7F84F67s1
       Rect: 61, 731, 152, 736
      Annotation: 
       Subtype: Link
       Contents: URI link to https://fra.europa.eu/en/publication/2018/handbook-european-non-discrimination-law-2018-edition
       Rect: 113, 704, 297, 711
      Annotation: 
       Subtype: Link
       Contents: URI link to https://fra.europa.eu/en/publication/2018/handbook-european-non-discrimination-law-2018-edition
       Rect: 61, 696, 165, 702
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib53C642B6EABA03007C8617C9A77D28CCs1
       Rect: 61, 689, 296, 694
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib53C642B6EABA03007C8617C9A77D28CCs1
       Rect: 61, 680, 240, 685
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibB9F303D70B0B76633C0C7FF3767590F9s1
       Rect: 61, 672, 296, 677
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibB9F303D70B0B76633C0C7FF3767590F9s1
       Rect: 61, 663, 296, 668
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibB9F303D70B0B76633C0C7FF3767590F9s1
       Rect: 61, 655, 121, 660
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibBF21FEF7BA543494849CBC8239B60DBAs1
       Rect: 61, 646, 296, 651
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibBF21FEF7BA543494849CBC8239B60DBAs1
       Rect: 61, 638, 296, 643
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibBF21FEF7BA543494849CBC8239B60DBAs1
       Rect: 61, 629, 279, 634
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibE3A27318F16269EEE788110D7C02069Bs1
       Rect: 61, 621, 296, 626
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibE3A27318F16269EEE788110D7C02069Bs1
       Rect: 61, 612, 296, 617
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibE3A27318F16269EEE788110D7C02069Bs1
       Rect: 61, 604, 128, 609
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibD2214A2C8851E89500D416F4E23231C2s1
       Rect: 61, 595, 296, 601
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibD2214A2C8851E89500D416F4E23231C2s1
       Rect: 61, 587, 296, 592
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibD2214A2C8851E89500D416F4E23231C2s1
       Rect: 61, 578, 296, 583
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibD2214A2C8851E89500D416F4E23231C2s1
       Rect: 61, 570, 186, 575
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibC7D6F3E549302B73F06944D8F4A93B56s1
       Rect: 61, 561, 296, 566
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibC7D6F3E549302B73F06944D8F4A93B56s1
       Rect: 61, 553, 243, 558
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibFEEA62E88014BAE259E4064ADF6BB22Bs1
       Rect: 61, 545, 296, 550
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibFEEA62E88014BAE259E4064ADF6BB22Bs1
       Rect: 61, 536, 296, 541
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibFEEA62E88014BAE259E4064ADF6BB22Bs1
       Rect: 61, 527, 296, 532
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibFEEA62E88014BAE259E4064ADF6BB22Bs1
       Rect: 61, 519, 102, 524
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib6B3B572E462F5BA77734C1AB2C0853FAs1
       Rect: 61, 511, 296, 516
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib6B3B572E462F5BA77734C1AB2C0853FAs1
       Rect: 61, 502, 296, 507
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib6B3B572E462F5BA77734C1AB2C0853FAs1
       Rect: 61, 493, 296, 498
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib6B3B572E462F5BA77734C1AB2C0853FAs1
       Rect: 61, 485, 133, 490
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib231CF627C323358D8C3187FDC8DAF24As1
       Rect: 61, 477, 296, 481
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib231CF627C323358D8C3187FDC8DAF24As1
       Rect: 61, 468, 195, 473
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibADD237D41434BAEBDB64BA7DBAC2A8B1s1
       Rect: 61, 460, 296, 465
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibADD237D41434BAEBDB64BA7DBAC2A8B1s1
       Rect: 61, 451, 296, 456
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibADD237D41434BAEBDB64BA7DBAC2A8B1s1
       Rect: 61, 443, 123, 447
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib9AA532900A8A4CEAF3ADA8930148B83Fs1
       Rect: 61, 434, 296, 439
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib9AA532900A8A4CEAF3ADA8930148B83Fs1
       Rect: 61, 426, 265, 431
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibAE75CDB46C334ADCB579110A86094B35s1
       Rect: 61, 417, 296, 422
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibAE75CDB46C334ADCB579110A86094B35s1
       Rect: 61, 409, 285, 414
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3483FF058DEDA3DAD41FA7925FAB2DACs1
       Rect: 61, 400, 296, 405
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3483FF058DEDA3DAD41FA7925FAB2DACs1
       Rect: 61, 392, 238, 397
      Annotation: 
       Subtype: Link
       Contents: URI link to https://djangoproject.com
       Rect: 169, 383, 244, 389
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib45DEABA288D2C5549F84B708DBFC1C1Bs1
       Rect: 61, 375, 296, 380
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib45DEABA288D2C5549F84B708DBFC1C1Bs1
       Rect: 61, 367, 283, 372
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibA30D23BBE55CEECC02656DA5265907C1s1
       Rect: 61, 358, 296, 363
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibA30D23BBE55CEECC02656DA5265907C1s1
       Rect: 61, 350, 296, 355
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibA30D23BBE55CEECC02656DA5265907C1s1
       Rect: 61, 341, 102, 346
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibAD63BC6E3C36DF844D32998319271336s1
       Rect: 61, 333, 217, 338
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib8BAC2AB472B804CE529179E2698AB26Fs1
       Rect: 61, 325, 296, 330
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib8BAC2AB472B804CE529179E2698AB26Fs1
       Rect: 61, 316, 235, 321
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib25FB005CE7A17FBD284FE9451A39B453s1
       Rect: 61, 308, 296, 313
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib25FB005CE7A17FBD284FE9451A39B453s1
       Rect: 61, 299, 231, 304
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib4E0709A60A1A8E87497D1B98CE67B97As1
       Rect: 61, 291, 296, 296
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib4E0709A60A1A8E87497D1B98CE67B97As1
       Rect: 61, 282, 129, 287
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibD16F2CF6B7D6A5D2690FE757EA22B307s1
       Rect: 61, 274, 296, 279
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibD16F2CF6B7D6A5D2690FE757EA22B307s1
       Rect: 61, 266, 160, 271
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3137CD2126409DD92F220FB06606DA55s1
       Rect: 61, 257, 295, 262
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib81312E2C9E085FD70ED30AE61F765D38s1
       Rect: 61, 249, 296, 254
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib81312E2C9E085FD70ED30AE61F765D38s1
       Rect: 61, 240, 216, 245
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibC00876968DC92D3D6C3BD1E2608C395Fs1
       Rect: 61, 232, 296, 238
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibC00876968DC92D3D6C3BD1E2608C395Fs1
       Rect: 61, 224, 230, 229
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib36E93CD75CEE109ADDABF51AAC49B558s1
       Rect: 61, 215, 211, 220
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibC149D9D5FA301EB839CA7F95B3A685ADs1
       Rect: 61, 207, 296, 212
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibC149D9D5FA301EB839CA7F95B3A685ADs1
       Rect: 61, 198, 296, 203
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibC149D9D5FA301EB839CA7F95B3A685ADs1
       Rect: 61, 190, 116, 195
      Annotation: 
       Subtype: Link
       Contents: URI link to https://www.govinfo.gov/content/pkg/CFR-2014-title29-vol4/xml/CFR-2014-title29-vol4-part1607.xml
       Rect: 402, 730, 566, 736
      Annotation: 
       Subtype: Link
       Contents: URI link to https://www.govinfo.gov/content/pkg/CFR-2014-title29-vol4/xml/CFR-2014-title29-vol4-part1607.xml
       Rect: 330, 721, 462, 728
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibD012A67E5426A5AF8A59655305E63721s1
       Rect: 330, 705, 565, 710
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibD012A67E5426A5AF8A59655305E63721s1
       Rect: 330, 697, 521, 702
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib4DF3B0B6342384D1C0D56AC20B66682Ds1
       Rect: 330, 688, 565, 693
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib4DF3B0B6342384D1C0D56AC20B66682Ds1
       Rect: 330, 679, 468, 684
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib777607BE270FD22EC69930BA1B8C3C3Cs1
       Rect: 330, 671, 508, 676
      Annotation: 
       Subtype: Link
       Contents: URI link to https://rdlab.cs.upc.edu/mydisk/
       Rect: 494, 661, 566, 668
      Annotation: 
       Subtype: Link
       Contents: URI link to https://rdlab.cs.upc.edu/mydisk/
       Rect: 330, 653, 354, 659
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib8B906ADDBF8BA474ADA5151AE1B5D4ECs1
       Rect: 330, 645, 565, 650
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib8B906ADDBF8BA474ADA5151AE1B5D4ECs1
       Rect: 330, 637, 565, 642
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib8B906ADDBF8BA474ADA5151AE1B5D4ECs1
       Rect: 330, 628, 466, 633
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib37E6D7141A7AC3CF8DF95F4DCB3F1DEAs1
       Rect: 330, 619, 565, 624
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib37E6D7141A7AC3CF8DF95F4DCB3F1DEAs1
       Rect: 330, 611, 565, 616
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib37E6D7141A7AC3CF8DF95F4DCB3F1DEAs1
       Rect: 330, 602, 565, 607
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3107E104764EEC1F7B9B26D9F27B1CC8s1
       Rect: 330, 594, 565, 599
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3107E104764EEC1F7B9B26D9F27B1CC8s1
       Rect: 330, 585, 514, 590
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibCA0F28DF3FD2CD0A8C025C108C75F9C2s1
       Rect: 330, 577, 565, 582
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibCA0F28DF3FD2CD0A8C025C108C75F9C2s1
       Rect: 330, 568, 565, 573
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibCA0F28DF3FD2CD0A8C025C108C75F9C2s1
       Rect: 330, 559, 461, 564
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib8785E441F92E2970D7564BA84D25F60Es1
       Rect: 330, 551, 565, 556
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib8785E441F92E2970D7564BA84D25F60Es1
       Rect: 330, 542, 565, 547
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib8785E441F92E2970D7564BA84D25F60Es1
       Rect: 330, 534, 426, 539
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib6FC86C5F35DF67AED52A9B461D29196Fs1
       Rect: 330, 525, 565, 530
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib6FC86C5F35DF67AED52A9B461D29196Fs1
       Rect: 330, 517, 524, 522
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib1AC093DBF25A073BF1B9F2339C20B68Fs1
       Rect: 330, 508, 565, 513
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib1AC093DBF25A073BF1B9F2339C20B68Fs1
       Rect: 330, 500, 565, 505
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib1AC093DBF25A073BF1B9F2339C20B68Fs1
       Rect: 330, 491, 395, 496
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib535BABA309E7030C4213BBADDF76044Fs1
       Rect: 330, 482, 565, 488
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib535BABA309E7030C4213BBADDF76044Fs1
       Rect: 330, 474, 565, 479
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib535BABA309E7030C4213BBADDF76044Fs1
       Rect: 330, 465, 386, 470
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibAABAF05111A5A5B139C51807C387C906s1
       Rect: 330, 457, 565, 462
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibAABAF05111A5A5B139C51807C387C906s1
       Rect: 330, 448, 565, 453
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibAABAF05111A5A5B139C51807C387C906s1
       Rect: 330, 440, 565, 445
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibAABAF05111A5A5B139C51807C387C906s1
       Rect: 330, 431, 378, 436
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib2CA68A3DACCAA623B75CA0AFBA9A923Es1
       Rect: 330, 422, 565, 427
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib2CA68A3DACCAA623B75CA0AFBA9A923Es1
       Rect: 330, 414, 527, 419
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibCC24EB7930967B52C3ED97077CE4E78Ds1
       Rect: 330, 405, 565, 410
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibCC24EB7930967B52C3ED97077CE4E78Ds1
       Rect: 330, 397, 565, 402
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibCC24EB7930967B52C3ED97077CE4E78Ds1
       Rect: 330, 388, 398, 393
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibA0B8000604823D6E7524F06F0EA9C21Ds1
       Rect: 330, 380, 565, 385
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibA0B8000604823D6E7524F06F0EA9C21Ds1
       Rect: 330, 371, 403, 376
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib0FE5774B2501864B44777B4483F82CDFs1
       Rect: 330, 362, 565, 367
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib0FE5774B2501864B44777B4483F82CDFs1
       Rect: 330, 354, 565, 359
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib0FE5774B2501864B44777B4483F82CDFs1
       Rect: 330, 345, 382, 350
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib4D746D325DA5F5B12C17088C079043C4s1
       Rect: 330, 337, 565, 342
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib4D746D325DA5F5B12C17088C079043C4s1
       Rect: 330, 328, 446, 333
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib6C1B2FE39038CA019904DB735A50DED0s1
       Rect: 330, 320, 565, 325
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib6C1B2FE39038CA019904DB735A50DED0s1
       Rect: 330, 311, 565, 316
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib6C1B2FE39038CA019904DB735A50DED0s1
       Rect: 330, 302, 382, 307
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3DC26EC04550CF6F23EE2BC516537E7Ds1
       Rect: 330, 294, 565, 299
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3DC26EC04550CF6F23EE2BC516537E7Ds1
       Rect: 330, 285, 565, 290
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib3DC26EC04550CF6F23EE2BC516537E7Ds1
       Rect: 330, 277, 367, 282
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib833FEF6FE844DDCF688A8B3C24E66142s1
       Rect: 330, 268, 565, 273
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib833FEF6FE844DDCF688A8B3C24E66142s1
       Rect: 330, 260, 565, 265
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bib833FEF6FE844DDCF688A8B3C24E66142s1
       Rect: 330, 251, 454, 256
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibFFFA662822DFA5E9FED4A88E21010E39s1
       Rect: 330, 243, 565, 247
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibFFFA662822DFA5E9FED4A88E21010E39s1
       Rect: 330, 234, 565, 239
      Annotation: 
       Subtype: Link
       Contents: URI link to http://refhub.elsevier.com/S2001-0370(25)00315-0/bibFFFA662822DFA5E9FED4A88E21010E39s1
       Rect: 330, 225, 478, 230
      Annotation: 
       Subtype: Link
       Contents: URI link to https://www.iso.org/standard/56064.html
       Rect: 330, 199, 452, 205
  Checksum: a0d2bcda
   Type: CRC32
  Checksum: 189b2c34ed78e93592bd99f745c1d807
   Type: MD5
  Checksum: 8a6933eda209529e0fc2ec29377970fb0dc01992
   Type: SHA-1
  Checksum: 1664bc38de02328090a839d957162b91db9427b98b6e0065d963594424e772be
   Type: SHA-256