eead17317700ff911cefe9e7fd18af84 321775.pdf 275e9f212e3de043eadc01443e9526f3d43881dc 321775.pdf 70c99c5d057ea9a4eef1b96fe97fe47221f731e5dee26af52f5622ca2a5dcf14 321775.pdf Title: Potential of facial biomarkers for Alzheimer's disease and obstructive sleep apnea in Down syndrome and general population Subject: The FASEB Journal 2025.39:e70480 Creator: Adobe InDesign 19.5 (Windows) Producer: Adobe PDF Library 17.0; modified using iText 4.2.0 by 1T3XT CreationDate: Wed Jun 4 11:37:06 2025 CEST ModDate: Wed Nov 26 08:46:22 2025 CET Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 16 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 2261221 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- VUFOTX+STIXTwoText-Italic Type 1C Custom yes yes yes 59 0 NQHNLN+STIXTwoText-Bold Type 1C Custom yes yes yes 58 0 HCOUTE+STIXTwoText Type 1C Custom yes yes yes 60 0 ULRDFZ+STIX-Regular Type 1C Custom yes yes yes 61 0 HCOUTE+STIXTwoText Type 1C Custom yes yes yes 796 0 Times-Roman Type 1 WinAnsi no no no 5 0 HCOUTE+STIXTwoText Type 1C Custom yes yes yes 678 0 HCOUTE+STIXTwoText Type 1C Custom yes yes yes 681 0 ITSJTX+STIX-Bold Type 1C Custom yes yes yes 151 0 BGBOZL+Arial-BoldMT Type 1C WinAnsi yes yes no 186 0 BGBOZL+SymbolMT CID TrueType Identity-H yes yes yes 228 0 BGBOZL+Arial-BoldMT Type 1C WinAnsi yes yes no 344 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-11-27 04:05:26 CET RepresentationInformation: 321775.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-11-26 13:02:41 CET Size: 2261221 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 2 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Language: en-US Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 228 ImageHeight: 45 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 228 ImageHeight: 45 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1006 ImageHeight: 1355 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2079 ImageHeight: 2139 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 875 ImageHeight: 707 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2079 ImageHeight: 586 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2079 ImageHeight: 2135 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2079 ImageHeight: 2134 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2079 ImageHeight: 1339 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Fonts: Type0: Font: BaseFont: BGBOZL+SymbolMT Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: ITSJTX+STIX-Bold FontSubset: true FirstChar: 31 LastChar: 31 FontDescriptor: FontName: ITSJTX+STIX-Bold Flags: Serif, Nonsymbolic FontBBox: -998, -552, 2000, 1055 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: BGBOZL+Arial-BoldMT FontSubset: true FirstChar: 32 LastChar: 112 FontDescriptor: FontName: BGBOZL+Arial-BoldMT Flags: Nonsymbolic FontBBox: -628, -376, 2000, 1018 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NQHNLN+STIXTwoText-Bold FontSubset: true FirstChar: 1 LastChar: 178 FontDescriptor: FontName: NQHNLN+STIXTwoText-Bold Flags: Serif, Symbolic FontBBox: -948, -434, 1429, 1047 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: BGBOZL+Arial-BoldMT FontSubset: true FirstChar: 48 LastChar: 57 FontDescriptor: FontName: BGBOZL+Arial-BoldMT Flags: Nonsymbolic FontBBox: -628, -376, 2000, 1018 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: VUFOTX+STIXTwoText-Italic FontSubset: true FirstChar: 1 LastChar: 173 FontDescriptor: FontName: VUFOTX+STIXTwoText-Italic Flags: Serif, Symbolic, Italic FontBBox: -893, -367, 1298, 1047 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: HCOUTE+STIXTwoText FontSubset: true FirstChar: 1 LastChar: 197 FontDescriptor: FontName: HCOUTE+STIXTwoText Flags: Serif, Symbolic FontBBox: -948, -373, 1297, 1047 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: ULRDFZ+STIX-Regular FontSubset: true FirstChar: 31 LastChar: 126 FontDescriptor: FontName: ULRDFZ+STIX-Regular Flags: Serif, Nonsymbolic FontBBox: -970, -486, 2208, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true CIDFontType2: Font: BaseFont: BGBOZL+SymbolMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: BGBOZL+SymbolMT Flags: Symbolic FontBBox: 0, -220, 1113, 1005 FontFile2: true XMP: application/pdfdoi:10.1096/fj.202403009R 10.1096/fj.202403009Rhttps://doi.org/10.1096/fj.202403009R 2025-03-24truefaseb.onlinelibrary.wiley.com10.1096/fj.202403009R faseb.onlinelibrary.wiley.comtrue10.1096/fj.202403009R2025-03-24 VoR Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 44, 23, 157, 13 Annotation: Subtype: Link Rect: 186, 589, 190, 567 ActionDest: 691 Annotation: Subtype: Link Rect: 190, 583, 202, 571 Annotation: Subtype: Link Rect: 293, 589, 297, 567 ActionDest: 691 Annotation: Subtype: Link Rect: 297, 583, 310, 571 Annotation: Subtype: Link Rect: 426, 589, 430, 567 ActionDest: 691 Annotation: Subtype: Link Rect: 430, 583, 443, 571 Annotation: Subtype: Link Rect: 108, 571, 125, 549 ActionDest: 691 Annotation: Subtype: Link Rect: 125, 565, 137, 553 Annotation: Subtype: Link Rect: 269, 571, 286, 549 ActionDest: 691 Annotation: Subtype: Link Rect: 286, 565, 298, 553 Annotation: Subtype: Link Rect: 386, 571, 390, 549 ActionDest: 691 Annotation: Subtype: Link Rect: 390, 565, 403, 553 Annotation: Subtype: Link Rect: 471, 571, 475, 549 ActionDest: 691 Annotation: Subtype: Link Rect: 475, 565, 487, 553 Annotation: Subtype: Link Rect: 111, 553, 115, 531 ActionDest: 691 Annotation: Subtype: Link Rect: 115, 547, 128, 535 Annotation: Subtype: Link Rect: 194, 553, 205, 531 ActionDest: 691 Annotation: Subtype: Link Rect: 205, 547, 217, 535 Annotation: Subtype: Link Rect: 352, 553, 352, 531 Annotation: Subtype: Link Rect: 352, 553, 356, 531 ActionDest: 691 Annotation: Subtype: Link Rect: 356, 547, 369, 535 Annotation: Subtype: Link Rect: 473, 127, 531, 116 Annotation: Subtype: Link Rect: 352, 105, 535, 94 Annotation: Subtype: Link Rect: 45, 94, 163, 83 Annotation: Subtype: Link Rect: 69, 283, 146, 272 Annotation: Subtype: Link Rect: 200, 73, 343, 64 Annotation: Subtype: Link Rect: 519, 782, 595, 767 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 240, 395, 244, 380 ActionDest: 413 Annotation: Subtype: Link Rect: 81, 330, 84, 315 ActionDest: 413 Annotation: Subtype: Link Rect: 232, 265, 246, 250 ActionDest: 413 Annotation: Subtype: Link Rect: 156, 239, 164, 224 ActionDest: 413 Annotation: Subtype: Link Rect: 66, 226, 70, 211 ActionDest: 413 Annotation: Subtype: Link Rect: 228, 226, 231, 211 ActionDest: 413 Annotation: Subtype: Link Rect: 189, 174, 193, 159 ActionDest: 413 Annotation: Subtype: Link Rect: 75, 148, 78, 133 ActionDest: 413 Annotation: Subtype: Link Rect: 209, 122, 212, 107 ActionDest: 413 Annotation: Subtype: Link Rect: 245, 96, 254, 81 ActionDest: 413 Annotation: Subtype: Link Rect: 180, 70, 196, 55 ActionDest: 413 Annotation: Subtype: Link Rect: 62, 57, 78, 42 ActionDest: 413 Annotation: Subtype: Link Rect: 281, 57, 288, 42 ActionDest: 413 Annotation: Subtype: Link Rect: 340, 408, 347, 393 ActionDest: 413 Annotation: Subtype: Link Rect: 353, 395, 369, 379 ActionDest: 413 Annotation: Subtype: Link Rect: 441, 395, 457, 379 ActionDest: 413 Annotation: Subtype: Link Rect: 386, 369, 393, 354 ActionDest: 413 Annotation: Subtype: Link Rect: 465, 291, 482, 276 ActionDest: 413 Annotation: Subtype: Link Rect: 329, 239, 336, 224 ActionDest: 539 Annotation: Subtype: Link Rect: 403, 213, 410, 198 ActionDest: 413 Annotation: Subtype: Link Rect: 396, 148, 403, 133 ActionDest: 539 Annotation: Subtype: Link Rect: 352, 96, 369, 81 ActionDest: 539 Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 86, 733, 119, 718 ActionDest: 539 Annotation: Subtype: Link Rect: 222, 694, 239, 679 ActionDest: 539 Annotation: Subtype: Link Rect: 87, 655, 103, 640 ActionDest: 539 Annotation: Subtype: Link Rect: 221, 577, 228, 562 ActionDest: 539 Annotation: Subtype: Link Rect: 124, 564, 131, 549 ActionDest: 539 Annotation: Subtype: Link Rect: 157, 525, 175, 510 ActionDest: 539 Annotation: Subtype: Link Rect: 211, 499, 218, 484 ActionDest: 539 Annotation: Subtype: Link Rect: 107, 187, 125, 172 ActionDest: 539 Annotation: Subtype: Link Rect: 186, 161, 204, 146 ActionDest: 539 Annotation: Subtype: Link Rect: 514, 733, 521, 718 ActionDest: 539 Annotation: Subtype: Link Rect: 455, 512, 460, 497 ActionDest: 148 Annotation: Subtype: Link Rect: 399, 447, 404, 432 ActionDest: 148 Annotation: Subtype: Link Rect: 462, 447, 472, 432 ActionDest: 618 Annotation: Subtype: Link Rect: 340, 330, 350, 315 ActionDest: 618 Annotation: Subtype: Link Rect: 392, 226, 467, 211 Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 139, 382, 146, 367 ActionDest: 539 Annotation: Subtype: Link Rect: 182, 343, 189, 328 ActionDest: 413 Annotation: Subtype: Link Rect: 129, 291, 137, 276 ActionDest: 539 Annotation: Subtype: Link Rect: 172, 187, 177, 172 ActionDest: 148 Annotation: Subtype: Link Rect: 96, 174, 104, 159 ActionDest: 413 Annotation: Subtype: Link Rect: 425, 473, 432, 458 ActionDest: 539 Annotation: Subtype: Link Rect: 364, 408, 367, 393 ActionDest: 413 Annotation: Subtype: Link Rect: 407, 369, 412, 353 ActionDest: 148 Annotation: Subtype: Link Rect: 343, 252, 353, 237 ActionDest: 618 Annotation: Subtype: Link Rect: 356, 148, 366, 133 ActionDest: 618 Annotation: Subtype: Link Rect: 401, 83, 406, 68 ActionDest: 183 Annotation: Subtype: Link Rect: 462, 83, 472, 68 ActionDest: 618 Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 97, 304, 104, 289 ActionDest: 539 Annotation: Subtype: Link Rect: 154, 304, 161, 289 ActionDest: 539 Annotation: Subtype: Link Rect: 212, 291, 219, 276 ActionDest: 539 Annotation: Subtype: Link Rect: 211, 252, 218, 237 ActionDest: 539 Annotation: Subtype: Link Rect: 281, 174, 288, 159 ActionDest: 539 Annotation: Subtype: Link Rect: 156, 122, 163, 107 ActionDest: 539 Annotation: Subtype: Link Rect: 216, 70, 223, 55 ActionDest: 539 Annotation: Subtype: Link Rect: 440, 668, 447, 653 ActionDest: 539 Annotation: Subtype: Link Rect: 331, 629, 338, 614 ActionDest: 539 Annotation: Subtype: Link Rect: 360, 590, 367, 575 ActionDest: 539 Annotation: Subtype: Link Rect: 534, 538, 549, 523 ActionDest: 539 Annotation: Subtype: Link Rect: 505, 499, 520, 484 ActionDest: 618 Annotation: Subtype: Link Rect: 330, 252, 337, 237 ActionDest: 539 Annotation: Subtype: Link Rect: 376, 161, 392, 146 ActionDest: 618 Annotation: Subtype: Link Rect: 483, 122, 490, 107 ActionDest: 618 Annotation: Subtype: Link Rect: 173, 370, 181, 358 ActionDest: 618 Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 204, 720, 211, 705 ActionDest: 618 Annotation: Subtype: Link Rect: 134, 707, 141, 692 ActionDest: 618 Annotation: Subtype: Link Rect: 123, 564, 132, 549 ActionDest: 618 Annotation: Subtype: Link Rect: 74, 525, 83, 510 ActionDest: 618 Annotation: Subtype: Link Rect: 203, 460, 223, 445 ActionDest: 278 Annotation: Subtype: Link Rect: 227, 317, 236, 301 ActionDest: 618 Annotation: Subtype: Link Rect: 140, 200, 162, 185 ActionDest: 278 Annotation: Subtype: Link Rect: 249, 161, 269, 146 ActionDest: 278 Annotation: Subtype: Link Rect: 520, 655, 533, 640 ActionDest: 289 Annotation: Subtype: Link Rect: 525, 616, 543, 600 ActionDest: 618 Annotation: Subtype: Link Rect: 363, 551, 376, 536 ActionDest: 289 Annotation: Subtype: Link Rect: 341, 434, 352, 419 ActionDest: 289 Annotation: Subtype: Link Rect: 481, 408, 497, 392 ActionDest: 618 Annotation: Subtype: Link Rect: 532, 408, 543, 392 ActionDest: 289 Annotation: Subtype: Link Rect: 500, 343, 512, 327 ActionDest: 289 Annotation: Subtype: Link Rect: 375, 317, 392, 301 ActionDest: 618 Annotation: Subtype: Link Rect: 429, 317, 441, 301 ActionDest: 289 Annotation: Subtype: Link Rect: 372, 291, 384, 276 ActionDest: 289 Annotation: Subtype: Link Rect: 341, 278, 353, 263 ActionDest: 289 Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 75, 70, 85, 55 ActionDest: 618 Annotation: Subtype: Link Rect: 121, 70, 126, 55 ActionDest: 289 Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 80, 174, 92, 159 ActionDest: 322 Annotation: Subtype: Link Rect: 270, 135, 282, 119 ActionDest: 322 Annotation: Subtype: Link Rect: 247, 122, 259, 106 ActionDest: 322 Annotation: Subtype: Link Rect: 173, 70, 186, 54 ActionDest: 333 Annotation: Subtype: Link Rect: 411, 473, 433, 458 ActionDest: 333 Annotation: Subtype: Link Rect: 382, 434, 394, 418 ActionDest: 333 Annotation: Subtype: Link Rect: 342, 421, 353, 406 ActionDest: 333 Annotation: Subtype: Link Rect: 478, 408, 491, 393 ActionDest: 333 Annotation: Subtype: Link Rect: 431, 382, 442, 367 ActionDest: 333 Annotation: Subtype: Link Rect: 342, 278, 347, 263 ActionDest: 342 Annotation: Subtype: Link Rect: 424, 187, 434, 171 ActionDest: 618 Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 209, 122, 230, 107 ActionDest: 381 Annotation: Subtype: Link Rect: 299, 150, 303, 138 ActionDest: 278 Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 246, 151, 251, 139 ActionDest: 278 Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 59, 421, 83, 406 ActionDest: 413 Annotation: Subtype: Link Rect: 151, 317, 167, 302 ActionDest: 618 Annotation: Subtype: Link Rect: 144, 304, 151, 289 ActionDest: 618 Annotation: Subtype: Link Rect: 205, 278, 212, 263 ActionDest: 618 Annotation: Subtype: Link Rect: 198, 252, 215, 237 ActionDest: 618 Annotation: Subtype: Link Rect: 76, 148, 83, 133 ActionDest: 618 Annotation: Subtype: Link Rect: 193, 148, 208, 133 ActionDest: 618 Annotation: Subtype: Link Rect: 98, 96, 113, 81 ActionDest: 618 Annotation: Subtype: Link Rect: 390, 668, 397, 653 ActionDest: 539 Annotation: Subtype: Link Rect: 322, 525, 329, 510 ActionDest: 413 Annotation: Subtype: Link Rect: 408, 395, 415, 380 ActionDest: 539 Annotation: Subtype: Link Rect: 487, 395, 494, 380 ActionDest: 539 Annotation: Subtype: Link Rect: 367, 382, 374, 367 ActionDest: 539 Annotation: Subtype: Link Rect: 407, 382, 414, 367 ActionDest: 539 Annotation: Subtype: Link Rect: 480, 174, 484, 159 ActionDest: 413 Page: Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 105, 252, 113, 237 ActionDest: 618 Annotation: Subtype: Link Rect: 270, 226, 288, 211 ActionDest: 539 Annotation: Subtype: Link Rect: 272, 57, 288, 42 ActionDest: 618 Annotation: Subtype: Link Rect: 319, 278, 335, 262 ActionDest: 413 Annotation: Subtype: Link Rect: 372, 278, 388, 262 ActionDest: 413 Annotation: Subtype: Link Rect: 524, 252, 549, 237 ActionDest: 413 Annotation: Subtype: Link Rect: 366, 174, 384, 159 ActionDest: 618 Annotation: Subtype: Link Rect: 340, 122, 352, 107 ActionDest: 413 Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 194, 252, 265, 237 Annotation: Subtype: Link Rect: 366, 564, 426, 549 Page: Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 147, 382, 159, 369 Annotation: Subtype: Link Rect: 160, 382, 215, 367 Annotation: Subtype: Link Rect: 45, 369, 151, 354 Annotation: Subtype: Link Rect: 99, 356, 111, 343 Annotation: Subtype: Link Rect: 111, 356, 274, 341 Annotation: Subtype: Link Rect: 118, 343, 130, 330 Annotation: Subtype: Link Rect: 131, 343, 186, 328 Annotation: Subtype: Link Rect: 45, 330, 151, 315 Annotation: Subtype: Link Rect: 92, 317, 104, 304 Annotation: Subtype: Link Rect: 104, 317, 267, 302 Annotation: Subtype: Link Rect: 130, 304, 143, 291 Annotation: Subtype: Link Rect: 143, 304, 199, 289 Annotation: Subtype: Link Rect: 45, 291, 153, 276 Annotation: Subtype: Link Rect: 98, 278, 110, 265 Annotation: Subtype: Link Rect: 110, 278, 272, 263 Annotation: Subtype: Link Rect: 82, 265, 94, 252 Annotation: Subtype: Link Rect: 95, 265, 257, 250 Annotation: Subtype: Link Rect: 94, 252, 107, 239 Annotation: Subtype: Link Rect: 107, 252, 269, 237 Annotation: Subtype: Link Rect: 81, 239, 94, 226 Annotation: Subtype: Link Rect: 94, 239, 258, 224 Annotation: Subtype: Link Rect: 133, 226, 145, 213 Annotation: Subtype: Link Rect: 145, 226, 201, 211 Annotation: Subtype: Link Rect: 45, 213, 151, 198 Annotation: Subtype: Link Rect: 222, 149, 288, 137 Annotation: Subtype: Link Rect: 63, 138, 102, 125 Annotation: Subtype: Link Rect: 257, 115, 288, 102 Annotation: Subtype: Link Rect: 63, 103, 140, 91 Annotation: Subtype: Link Rect: 77, 57, 200, 45 Annotation: Subtype: Link Rect: 519, 724, 549, 712 Annotation: Subtype: Link Rect: 324, 713, 405, 701 Annotation: Subtype: Link Rect: 482, 678, 543, 666 Annotation: Subtype: Link Rect: 514, 644, 549, 632 Annotation: Subtype: Link Rect: 324, 632, 384, 620 Annotation: Subtype: Link Rect: 479, 586, 545, 574 Annotation: Subtype: Link Rect: 519, 552, 549, 540 Annotation: Subtype: Link Rect: 324, 540, 373, 528 Annotation: Subtype: Link Rect: 355, 506, 425, 494 Annotation: Subtype: Link Rect: 405, 471, 474, 459 Annotation: Subtype: Link Rect: 519, 437, 549, 425 Annotation: Subtype: Link Rect: 324, 425, 395, 413 Annotation: Subtype: Link Rect: 338, 379, 435, 367 Annotation: Subtype: Link Rect: 338, 333, 439, 321 Annotation: Subtype: Link Rect: 519, 310, 549, 298 Annotation: Subtype: Link Rect: 324, 299, 368, 287 Annotation: Subtype: Link Rect: 355, 253, 462, 241 Annotation: Subtype: Link Rect: 338, 207, 457, 195 Annotation: Subtype: Link Rect: 428, 172, 504, 160 Annotation: Subtype: Link Rect: 338, 126, 429, 114 Annotation: Subtype: Link Rect: 414, 80, 527, 68 Page: Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 257, 738, 288, 726 Annotation: Subtype: Link Rect: 63, 726, 146, 714 Annotation: Subtype: Link Rect: 93, 680, 208, 668 Annotation: Subtype: Link Rect: 127, 634, 228, 622 Annotation: Subtype: Link Rect: 181, 600, 277, 588 Annotation: Subtype: Link Rect: 140, 565, 237, 553 Annotation: Subtype: Link Rect: 187, 531, 288, 519 Annotation: Subtype: Link Rect: 172, 496, 240, 484 Annotation: Subtype: Link Rect: 77, 462, 152, 450 Annotation: Subtype: Link Rect: 77, 416, 189, 404 Annotation: Subtype: Link Rect: 257, 347, 288, 335 Annotation: Subtype: Link Rect: 63, 335, 132, 323 Annotation: Subtype: Link Rect: 77, 289, 158, 277 Annotation: Subtype: Link Rect: 257, 255, 288, 243 Annotation: Subtype: Link Rect: 63, 243, 151, 231 Annotation: Subtype: Link Rect: 197, 209, 273, 197 Annotation: Subtype: Link Rect: 257, 174, 288, 162 Annotation: Subtype: Link Rect: 63, 163, 111, 151 Annotation: Subtype: Link Rect: 77, 117, 172, 105 Annotation: Subtype: Link Rect: 201, 82, 266, 70 Annotation: Subtype: Link Rect: 355, 726, 480, 714 Annotation: Subtype: Link Rect: 338, 657, 407, 645 Annotation: Subtype: Link Rect: 519, 623, 549, 611 Annotation: Subtype: Link Rect: 324, 611, 390, 599 Annotation: Subtype: Link Rect: 418, 588, 517, 576 Annotation: Subtype: Link Rect: 459, 565, 544, 553 Annotation: Subtype: Link Rect: 383, 519, 452, 507 Annotation: Subtype: Link Rect: 338, 404, 431, 392 Annotation: Subtype: Link Rect: 519, 358, 549, 346 Annotation: Subtype: Link Rect: 324, 347, 390, 335 Annotation: Subtype: Link Rect: 401, 301, 496, 289 Annotation: Subtype: Link Rect: 389, 197, 498, 185 Annotation: Subtype: Link Rect: 338, 151, 447, 139 Annotation: Subtype: Link Rect: 430, 128, 526, 116 Annotation: Subtype: Link Rect: 350, 94, 410, 82 Annotation: Subtype: Link Rect: 519, 71, 549, 59 Annotation: Subtype: Link Rect: 324, 59, 420, 47 Page: Sequence: 16 Annotations: Annotation: Subtype: Link Rect: 153, 715, 221, 703 Annotation: Subtype: Link Rect: 77, 669, 168, 657 Annotation: Subtype: Link Rect: 219, 646, 279, 634 Annotation: Subtype: Link Rect: 224, 611, 288, 599 Annotation: Subtype: Link Rect: 63, 600, 101, 588 Annotation: Subtype: Link Rect: 93, 565, 213, 553 Annotation: Subtype: Link Rect: 144, 531, 229, 519 Annotation: Subtype: Link Rect: 253, 508, 288, 496 Annotation: Subtype: Link Rect: 63, 496, 127, 484 Annotation: Subtype: Link Rect: 77, 462, 177, 450 Annotation: Subtype: Link Rect: 77, 416, 173, 404 Annotation: Subtype: Link Rect: 98, 370, 191, 358 Annotation: Subtype: Link Rect: 77, 324, 196, 312 Annotation: Subtype: Link Rect: 173, 289, 265, 277 Annotation: Subtype: Link Rect: 148, 243, 277, 231 Annotation: Subtype: Link Rect: 426, 726, 504, 714 Annotation: Subtype: Link Rect: 517, 692, 549, 680 Annotation: Subtype: Link Rect: 324, 680, 370, 668 Annotation: Subtype: Link Rect: 418, 646, 512, 634 Annotation: Subtype: Link Rect: 519, 611, 549, 599 Annotation: Subtype: Link Rect: 324, 600, 394, 588 Annotation: Subtype: Link Rect: 410, 554, 482, 542 Annotation: Subtype: Link Rect: 519, 519, 549, 507 Annotation: Subtype: Link Rect: 324, 508, 355, 496 Annotation: Subtype: Link Rect: 338, 473, 469, 461 Annotation: Subtype: Link Rect: 424, 427, 538, 415 Annotation: Subtype: Link Rect: 404, 245, 500, 230 Checksum: 9f419610 Type: CRC32 Checksum: eead17317700ff911cefe9e7fd18af84 Type: MD5 Checksum: 275e9f212e3de043eadc01443e9526f3d43881dc Type: SHA-1 Checksum: 70c99c5d057ea9a4eef1b96fe97fe47221f731e5dee26af52f5622ca2a5dcf14 Type: SHA-256