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Silverberg Creator: Springer Producer: Acrobat Distiller 10.1.8 (Windows) CreationDate: Fri Feb 14 16:03:01 2025 CET ModDate: Fri Mar 7 17:10:50 2025 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 19 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 1606300 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- AMQGHO+STIX-Regular Type 1C WinAnsi yes yes yes 975 0 StoneSerifStd-Semibold Type 1C Custom yes no yes 984 0 StoneSerifStd-Medium Type 1C Custom yes no yes 989 0 CNIDMG+StoneSansStd-Medium Type 1C WinAnsi yes yes yes 990 0 StoneSerifStd-SemiboldIt Type 1C Custom yes no yes 991 0 MDDGTU+Wingdings-Regular Type 1C WinAnsi yes yes yes 1001 0 AMQGHO+STIX-Regular2 Type 1C WinAnsi yes yes yes 1018 0 StoneSansStd-Bold Type 1C WinAnsi yes no yes 426 0 StoneSerifStd-MediumItalic Type 1C WinAnsi yes no yes 512 0 REWARG+GaramondPremrPro-Smbd Type 1C WinAnsi yes yes yes 527 0 JATEJW+GaramondPremrPro Type 1C Custom yes yes yes 520 0 LELBLS+TimesNewRomanPSMT CID TrueType Identity-H yes yes yes 871 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-11-27 04:05:17 CET RepresentationInformation: 321779.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-11-26 13:38:30 CET Size: 1606300 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 1073 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: Lebrikizumab vs Other Systemic Monotherapies for Moderate-to-Severe Atopic Dermatitis: Network Meta-analysis of Efficacy Children: Item: Title: Abstract Children: Item: Title: Introduction: Item: Title: Methods: Item: Title: Results: Item: Title: Conclusion: Item: Title: Introduction Item: Title: Methods Children: Item: Title: Ethical Approval Item: Title: Data Sources and Study Selection Item: Title: Efficacy Outcomes Item: Title: Statistical Analysis Item: Title: Results Children: Item: Title: Systematic Literature Review Item: Title: Feasibility Assessment and Model Fit Item: Title: Efficacy Endpoints Item: Title: NNT Item: Title: Sensitivity Analyses Item: Title: Discussion Item: Title: Conclusion Item: Title: References Info: Title: Lebrikizumab vs Other Systemic Monotherapies for Moderate-to-Severe Atopic Dermatitis: Network Meta-analysis of Efficacy Author: Jonathan I. 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Eczema Area and Severity Index; Investigator Global Assessment; Lebrikizumab; Network meta-analysis; Pruritus/itch Numeric Rating Scale application/pdf https://doi.org/10.1007/s13555-025-01357-7 Springer Healthcare Dermatology and Therapy, https://doi.org/10.1007/s13555-025-01357-7 Atopic dermatitis Eczema Area and Severity Index Investigator Global Assessment Lebrikizumab Network meta-analysis Pruritus/itch Numeric Rating Scale Lebrikizumab vs Other Systemic Monotherapies for Moderate-to-Severe Atopic Dermatitis: Network Meta-analysis of Efficacy Jonathan I. Silverberg Thomas Bieber Amy S. Paller Lisa Beck Masahiro Kamata Luis Puig Marni Wiseman Khaled Ezzedine Alan D. 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