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EN Outlines: Item: Title: Metformina: paradigma de pleiotropismo terapéutico (1922-2025) Destination: 1 Children: Item: Title: Introducción: de Galega officinalis a metformina Destination: 1 Item: Title: Metformina: acciones sobre el metabolismo intermediario Destination: 1 Item: Title: Metformina: intervenciones terapéuticas Destination: 1 Children: Item: Title: Metformina y diabetes mellitus tipo 2 Destination: 1 Item: Title: Metformina y prediabetes Destination: 1 Item: Title: Metformina y diabetes gestacional Destination: 1 Item: Title: Metformina y síndrome de ovario poliquístico Destination: 1 Item: Title: Tolerancia a la metformina: efectos secundarios adversos Destination: 1 Children: Item: Title: Metformina: intolerancia gastrointestinal Destination: 1 Item: Title: Metformina: efectos sobre los niveles séricos de vitamina B12 Destination: 1 Item: Title: Metformina: efectos adversos sobre el sistema reproductor masculino y anomalías congénitas neonatales en varones expuestos Destination: 1 Item: Title: Metformina: nuevas investigaciones en curso y perspectivas de futuro Destination: 1 Children: Item: Title: Metformina: acciones sobre el apetito Destination: 1 Item: Title: Metformina: microbiota gastrointestinal Destination: 1 Item: Title: Metformina y protección cardiovascular Destination: 1 Item: Title: Metformina: efecto renoprotector en pacientes con DM2 Destination: 1 Item: Title: Metformina: cáncer Destination: 1 Item: Title: Metformina y longevidad Destination: 1 Item: Title: Metformina: fibrosis pulmonar idiopática Destination: 1 Item: Title: Conclusiones Destination: 1 Item: Title: Consideraciones éticas Destination: 1 Item: Title: Financiación Destination: 1 Item: Title: Conflicto de intereses Destination: 1 Item: Title: Bibliografía Destination: 1 Info: Title: Metformina: paradigma de pleiotropismo terapéutico (1922-2025) Author: Alberto de Leiva Hidalgo Subject: Medicina Clinica, 165 (2025) 107189. doi:10.1016/j.medcli.2025.107189 Keywords: 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