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Addition to Targeted Biopsy: Results from a Systematic Review and Meta-analysis Destination: 1 Children: Item: Title: 1 Introduction Destination: 1 Item: Title: 2 Methods Destination: 1 Children: Item: Title: 2.1 Search strategy Destination: 1 Item: Title: 2.2 Studies’ selection and main outcomes Destination: 1 Item: Title: 2.3 Data extraction Destination: 1 Item: Title: 2.4 Risk of bias assessment Destination: 1 Item: Title: 2.5 Subgroup analyses Destination: 1 Item: Title: 2.6 Statistical analysis Destination: 1 Item: Title: 3 Results Destination: 1 Children: Item: Title: 3.1 Study selection and characteristics Destination: 1 Item: Title: 3.2 RoB and study heterogeneity Destination: 1 Item: Title: 3.3 Primary outcome: detection yields of csPCa Destination: 1 Item: Title: 3.4 Secondary outcomes Destination: 1 Children: Item: Title: 3.4.1 Detection yields of insignPCa Destination: 1 Item: Title: 3.4.2 Detection yields of higher-grade PCa Destination: 1 Item: Title: 3.4.3 Bx complications—side effects Destination: 1 Item: Title: 3.5 Subgroups analysis Destination: 1 Children: Item: Title: 3.5.1 Detection yields of csPCa according to RBx strategies Destination: 1 Item: Title: 3.5.2 Detection yields of csPCa according to PI-RADS or Likert scores Destination: 1 Item: Title: 3.5.3 Detection yields of csPCa according to transperineal/transrectal routes Destination: 1 Item: Title: 3.5.4 Detection yields of csPCa according to SBx templates Destination: 1 Item: Title: 3.5.5 Detection yields of csPCa according to lesion size Destination: 1 Item: Title: 3.5.6 Detection yields of csPCa for Bx-naïve versus previously biopsied patients Destination: 1 Item: Title: 4 Discussion Destination: 1 Item: Title: 5 Conclusions Destination: 1 Item: Title: Appendix A Supplementary data Destination: 1 Item: Title: References Destination: 1 Info: Title: Regional Versus Systematic Biopsy in Addition to Targeted Biopsy: Results from a Systematic Review and Meta-analysis Author: Francesco Sanguedolce Subject: European Urology Oncology, 8 (2025) 534-543. doi:10.1016/j.euo.2024.10.006 Creator: Elsevier Producer: Acrobat Distiller 24.0 (Windows) CreationDate: Wed Mar 19 14:15:03 CET 2025 ModDate: Wed Mar 19 14:16:06 CET 2025 ID: 0x06e2dc85c28d213ffd7add9ff29b0c78, 0x1608aed934190946aacae78cc6df2f4f Filters: FilterPipeline: FlateDecode FilterPipeline: CCITTFaxDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/tiff CompressionScheme: CCITT Group 4 ImageWidth: 1651 ImageHeight: 466 BitsPerSample: 1 BitsPerSampleUnit: integer ImageMask: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 295 ImageHeight: 354 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1997 ImageHeight: 2058 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 140 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Baboudjian Gianluca Giannarini Valeria Panebianco Massimo Madonia Lars Budäus Morgan Roupret Joan Palou Alberto Breda Ivo Schoots Anwar R. Padhani the EAU Section of Urological Imaging (ESUI) Clinically significant prostate cancer Prostate magnetic resonance imaging Systematic prostate biopsy Targeted prostate biopsy Regional targeted prostate biopsy European Urology Oncology, 8 (2025) 534-543. doi:10.1016/j.euo.2024.10.006 The Authors journal European Urology Oncology © 2024 The Authors. 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Link Rect: 321, 494, 543, 501 Annotation: Subtype: Link Rect: 321, 485, 543, 492 Annotation: Subtype: Link Rect: 321, 476, 510, 483 Annotation: Subtype: Link Rect: 321, 467, 543, 474 Annotation: Subtype: Link Rect: 321, 458, 543, 465 Annotation: Subtype: Link Rect: 321, 449, 543, 456 Annotation: Subtype: Link Rect: 321, 440, 503, 447 Annotation: Subtype: Link Rect: 321, 431, 543, 438 Annotation: Subtype: Link Rect: 321, 422, 543, 429 Annotation: Subtype: Link Rect: 321, 414, 349, 421 Annotation: Subtype: Link Rect: 321, 405, 543, 412 Annotation: Subtype: Link Rect: 321, 396, 543, 403 Annotation: Subtype: Link Rect: 321, 387, 543, 394 Annotation: Subtype: Link Rect: 321, 378, 543, 385 Annotation: Subtype: Link Rect: 321, 369, 389, 376 Annotation: Subtype: Link Rect: 321, 360, 543, 367 Annotation: Subtype: Link Rect: 321, 351, 543, 358 Annotation: Subtype: Link Rect: 321, 342, 543, 349 Annotation: Subtype: Link Rect: 321, 333, 380, 340 Annotation: Subtype: Link Rect: 321, 324, 543, 331 Annotation: Subtype: Link Rect: 321, 315, 543, 322 Annotation: Subtype: Link Rect: 321, 306, 543, 313 Annotation: Subtype: Link Rect: 321, 297, 449, 304 Annotation: Subtype: Link Rect: 320, 288, 543, 295 Annotation: Subtype: Link Rect: 320, 279, 543, 286 Annotation: Subtype: Link Rect: 320, 270, 543, 277 Annotation: Subtype: Link Rect: 320, 261, 541, 268 Annotation: Subtype: Link Rect: 321, 252, 543, 259 Annotation: Subtype: Link Rect: 321, 243, 543, 250 Annotation: Subtype: Link Rect: 321, 234, 465, 241 Annotation: Subtype: Link Rect: 321, 225, 543, 232 Annotation: Subtype: Link Rect: 321, 216, 543, 223 Annotation: Subtype: Link Rect: 321, 207, 543, 214 Annotation: Subtype: Link Rect: 321, 198, 541, 205 Annotation: Subtype: Link Rect: 321, 189, 543, 196 Annotation: Subtype: Link Rect: 321, 180, 543, 187 Annotation: Subtype: Link Rect: 321, 171, 519, 178 Annotation: Subtype: Link Rect: 321, 162, 543, 169 Annotation: Subtype: Link Rect: 321, 154, 543, 161 Annotation: Subtype: Link Rect: 321, 145, 543, 151 Annotation: Subtype: Link Rect: 321, 136, 481, 143 Annotation: Subtype: Link Rect: 321, 127, 543, 134 Annotation: Subtype: Link Rect: 321, 118, 543, 125 Annotation: Subtype: Link Rect: 321, 109, 489, 116 Annotation: Subtype: Link Rect: 321, 100, 543, 107 Annotation: Subtype: Link Rect: 321, 91, 543, 98 Annotation: Subtype: Link Rect: 321, 82, 543, 89 Annotation: Subtype: Link Rect: 321, 73, 409, 80 Annotation: Subtype: Link Rect: 321, 64, 543, 71 Annotation: Subtype: Link Rect: 321, 55, 543, 62 Page: Label: 543 Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 68, 718, 291, 725 Annotation: Subtype: Link Rect: 68, 709, 140, 716 Annotation: Subtype: Link Rect: 68, 700, 290, 707 Annotation: Subtype: Link Rect: 68, 691, 290, 698 Annotation: Subtype: Link Rect: 68, 683, 131, 690 Annotation: Subtype: Link Rect: 68, 674, 290, 681 Annotation: Subtype: Link Rect: 68, 665, 291, 672 Annotation: Subtype: Link Rect: 68, 656, 167, 663 Annotation: Subtype: Link Rect: 68, 647, 290, 654 Annotation: Subtype: Link Rect: 68, 638, 289, 645 Annotation: Subtype: Link Rect: 68, 629, 290, 636 Annotation: Subtype: Link Rect: 68, 620, 290, 627 Annotation: Subtype: Link Rect: 68, 611, 264, 618 Annotation: Subtype: Link Rect: 68, 602, 290, 609 Annotation: Subtype: Link Rect: 68, 593, 291, 600 Annotation: Subtype: Link Rect: 68, 584, 290, 591 Annotation: Subtype: Link Rect: 68, 575, 119, 582 Annotation: Subtype: Link Rect: 68, 566, 291, 573 Annotation: Subtype: Link Rect: 68, 557, 291, 564 Annotation: Subtype: Link Rect: 68, 548, 251, 555 Annotation: Subtype: Link Rect: 68, 539, 290, 546 Annotation: Subtype: Link Rect: 68, 530, 290, 537 Annotation: Subtype: Link Rect: 68, 521, 291, 528 Annotation: Subtype: Link Rect: 68, 512, 249, 519 Annotation: Subtype: Link Rect: 68, 503, 291, 510 Annotation: Subtype: Link Rect: 68, 494, 291, 501 Annotation: Subtype: Link Rect: 68, 485, 275, 492 Annotation: Subtype: Link Rect: 68, 476, 290, 483 Annotation: Subtype: Link Rect: 68, 467, 290, 474 Annotation: Subtype: Link Rect: 68, 458, 290, 465 Annotation: Subtype: Link Rect: 68, 449, 241, 456 Annotation: Subtype: Link Rect: 68, 440, 290, 447 Annotation: Subtype: Link Rect: 68, 431, 291, 438 Annotation: Subtype: Link Rect: 68, 422, 291, 429 Annotation: Subtype: Link Rect: 68, 414, 128, 421 Annotation: Subtype: Link Rect: 68, 405, 291, 412 Annotation: Subtype: Link Rect: 68, 396, 291, 403 Annotation: Subtype: Link Rect: 68, 387, 289, 394 Annotation: Subtype: Link Rect: 68, 378, 290, 385 Annotation: Subtype: Link Rect: 68, 369, 290, 376 Annotation: Subtype: Link Rect: 68, 360, 275, 367 Annotation: Subtype: Link Rect: 325, 718, 547, 725 Annotation: Subtype: Link Rect: 325, 709, 547, 716 Annotation: Subtype: Link Rect: 325, 700, 433, 707 Annotation: Subtype: Link Rect: 325, 691, 547, 698 Annotation: Subtype: Link Rect: 325, 683, 547, 690 Annotation: Subtype: Link Rect: 325, 674, 547, 681 Annotation: Subtype: Link Rect: 325, 665, 409, 672 Annotation: Subtype: Link Rect: 325, 656, 547, 663 Annotation: Subtype: Link Rect: 325, 647, 547, 654 Annotation: Subtype: Link Rect: 325, 638, 432, 645 Annotation: Subtype: Link Rect: 325, 629, 547, 636 Annotation: Subtype: Link Rect: 325, 620, 545, 627 Annotation: Subtype: Link Rect: 325, 611, 547, 618 Annotation: Subtype: Link Rect: 325, 602, 547, 609 Annotation: Subtype: Link Rect: 325, 593, 547, 600 Annotation: Subtype: Link Rect: 325, 584, 547, 591 Annotation: Subtype: Link Rect: 325, 575, 372, 582 Annotation: Subtype: Link Rect: 325, 566, 547, 573 Annotation: Subtype: Link Rect: 325, 557, 547, 564 Annotation: Subtype: Link Rect: 325, 548, 547, 555 Annotation: Subtype: Link Rect: 325, 539, 350, 546 Annotation: Subtype: Link Rect: 325, 530, 547, 537 Annotation: Subtype: Link Rect: 325, 521, 547, 528 Annotation: Subtype: Link Rect: 325, 512, 547, 519 Annotation: Subtype: Link Rect: 325, 503, 514, 510 Annotation: Subtype: Link Rect: 325, 494, 547, 501 Annotation: Subtype: Link Rect: 325, 485, 547, 492 Annotation: Subtype: Link Rect: 325, 476, 427, 483 Annotation: Subtype: Link Rect: 475, 458, 547, 465 Annotation: Subtype: Link Rect: 325, 449, 530, 456 Annotation: Subtype: Link Rect: 325, 440, 444, 447 Annotation: Subtype: Link Rect: 325, 431, 547, 438 Annotation: Subtype: Link Rect: 325, 422, 547, 429 Annotation: Subtype: Link Rect: 325, 414, 427, 421 Annotation: Subtype: Link Rect: 325, 405, 547, 412 Annotation: Subtype: Link Rect: 325, 396, 547, 403 Annotation: Subtype: Link Rect: 325, 387, 442, 394 Checksum: eeeb9183 Type: CRC32 Checksum: 3bb9144f678744fb2d889da83d178b0e Type: MD5 Checksum: 4fafa1f6dbd3d8ea99eb2a1b91e1c812ff64c56a Type: SHA-1 Checksum: 8d42af96eb077fbe7654ef4a8dd59d40a6510b98694295cd88023986076b6b0d Type: SHA-256