c62d427b5850e5ce91edb3d84d2c1331 gashep_a2025v48n2e502216.pdf a1ca7edf6f3c233b94530ba076fa2dace23196ec gashep_a2025v48n2e502216.pdf 56b758bff9f3cf09145db48d324ab57ee6ffc3310c15e40229033c26985bafa8 gashep_a2025v48n2e502216.pdf Title: Preguntas comunes y respuestas razonadas sobre el síndrome del sobrecrecimiento bacteriano intestinal (SIBO) Subject: Gastroenterología y Hepatología, 48 (2025) 502216. doi:10.1016/j.gastrohep.2024.502216 Keywords: Author: Javier Alcedo González Creator: Elsevier Producer: Acrobat Distiller 24.0 (Windows) CreationDate: Wed Feb 5 12:29:17 2025 CET ModDate: Wed Feb 5 07:01:55 2025 CET Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 25 Encrypted: no Page size: 595.28 x 793.7 pts Page rot: 0 File size: 3797030 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MIPHIG+TrebuchetMS Type 1C Custom yes yes yes 767 0 MIPHIH+Times-Roman Type 1C WinAnsi yes yes no 768 0 MIPHNG+Univers Type 1C Custom yes yes yes 769 0 MIPIDF+TrebuchetMS-Bold Type 1C Custom yes yes yes 779 0 MIPIDG+MathematicalPi-Six Type 1C Custom yes yes no 785 0 MIPIEH+NmtmibA Type 1C Custom yes yes yes 786 0 MIPIEI+MTSYB Type 1C Custom yes yes yes 787 0 MIPIFI+TrebuchetMS-Italic Type 1C Custom yes yes yes 790 0 MIPIKH+MTSY Type 1C Custom yes yes yes 797 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-01-30 04:46:40 CET RepresentationInformation: gashep_a2025v48n2e502216.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-01-29 05:34:19 CET Size: 3797030 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 847 FreeObjects: 85 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Preguntas comunes y respuestas razonadas sobre el síndrome del sobrecrecimiento bacteriano intestinal (SIBO) Destination: 1 Children: Item: Title: Introducción Destination: 1 Item: Title: Metodología Destination: 1 Item: Title: ¿Cuáles son los síntomas del sobrecrecimiento bacteriano intestinal y cuándo debemos sospecharlo? Destination: 1 Item: Title: ¿Cuál es la validez diagnóstica de los test diagnósticos del sobrecrecimiento bacteriano intestinal? Destination: 1 Item: Title: ¿Predicen los test disponibles la respuesta al tratamiento? Destination: 1 Item: Title: ¿Qué utilidad tienen las medidas dietéticas? Destination: 1 Item: Title: ¿Cuál es el rendimiento de los antibióticos? Destination: 1 Item: Title: ¿Aportan beneficio los probióticos? Destination: 1 Item: Title: ¿Son una alternativa los remedios herbales? Destination: 1 Item: Title: Conclusiones Destination: 1 Item: Title: Declaraciones y grado de consenso Destination: 1 Item: Title: Financiación Destination: 1 Item: Title: Conflicto de intereses Destination: 1 Item: Title: Bibliografía Destination: 1 Info: Title: Preguntas comunes y respuestas razonadas sobre el síndrome del sobrecrecimiento bacteriano intestinal (SIBO) Author: Javier Alcedo González Subject: Gastroenterología y Hepatología, 48 (2025) 502216. doi:10.1016/j.gastrohep.2024.502216 Keywords: Creator: Elsevier Producer: Acrobat Distiller 24.0 (Windows) CreationDate: Wed Feb 05 12:29:17 CET 2025 ModDate: Wed Feb 05 07:31:55 CET 2025 ID: 0x692ea41c3efa6d254fedd4dd4ecc2fa9, 0xb6657df4f21cf748ba7fb478dc5385ea Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 308 ImageHeight: 337 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 121 ImageHeight: 120 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 295 ImageHeight: 372 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2051 ImageHeight: 1280 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1263 ImageHeight: 615 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1261 ImageHeight: 565 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1264 ImageHeight: 602 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1255 ImageHeight: 571 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1252 ImageHeight: 596 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1252 ImageHeight: 577 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1255 ImageHeight: 578 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1258 ImageHeight: 571 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1255 ImageHeight: 584 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1255 ImageHeight: 580 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1255 ImageHeight: 578 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1258 ImageHeight: 620 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1255 ImageHeight: 592 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1261 ImageHeight: 577 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1261 ImageHeight: 578 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1261 ImageHeight: 584 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1261 ImageHeight: 590 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1255 ImageHeight: 584 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1258 ImageHeight: 608 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1258 ImageHeight: 596 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1264 ImageHeight: 613 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1264 ImageHeight: 573 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1258 ImageHeight: 581 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1268 ImageHeight: 635 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1258 ImageHeight: 593 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: MIPHIH+Times-Roman FontSubset: true FirstChar: 32 LastChar: 237 FontDescriptor: FontName: MIPHIH+Times-Roman Flags: Serif, Nonsymbolic FontBBox: -168, -218, 1000, 898 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MIPHNG+Univers FontSubset: true FirstChar: 46 LastChar: 119 FontDescriptor: FontName: MIPHNG+Univers Flags: Symbolic FontBBox: -168, -250, 992, 947 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MIPIDG+MathematicalPi-Six FontSubset: true FirstChar: 2 LastChar: 2 FontDescriptor: FontName: MIPIDG+MathematicalPi-Six Flags: Symbolic FontBBox: 0, -188, 990, 742 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: MIPIEH+NmtmibA FontSubset: true FirstChar: 44 LastChar: 44 FontDescriptor: FontName: MIPIEH+NmtmibA Flags: Symbolic, ForceBold FontBBox: -71, -209, 987, 767 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MIPIEI+MTSYB FontSubset: true FirstChar: 2 LastChar: 2 FontDescriptor: FontName: MIPIEI+MTSYB Flags: Symbolic, ForceBold FontBBox: -16, -935, 1043, 896 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MIPIFI+TrebuchetMS-Italic FontSubset: true FirstChar: 31 LastChar: 250 FontDescriptor: FontName: MIPIFI+TrebuchetMS-Italic Flags: Serif, Symbolic, Italic FontBBox: -86, -258, 1021, 946 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MIPIDF+TrebuchetMS-Bold FontSubset: true FirstChar: 40 LastChar: 243 FontDescriptor: FontName: MIPIDF+TrebuchetMS-Bold Flags: Serif, Symbolic, ForceBold FontBBox: -101, -270, 1010, 980 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MIPIKH+MTSY FontSubset: true FirstChar: 2 LastChar: 177 FontDescriptor: FontName: MIPIKH+MTSY Flags: Symbolic FontBBox: 0, -954, 1043, 796 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: MIPHIG+TrebuchetMS FontSubset: true FirstChar: 31 LastChar: 250 FontDescriptor: FontName: MIPHIG+TrebuchetMS Flags: Serif, Symbolic FontBBox: -86, -262, 958, 939 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true XMP: application/pdf 10.1016/j.gastrohep.2024.502216 Preguntas comunes y respuestas razonadas sobre el síndrome del sobrecrecimiento bacteriano intestinal (SIBO) Javier Alcedo González Fermín Estremera-Arévalo Julyssa Cobián Malaver Javier Santos Vicente Luis Gerardo Alcalá-González Juan Naves Elizabeth Barba Orozco Claudia Barber Caselles Blanca Serrano-Falcón Anna Accarino Garaventa Carmen Alonso-Cotoner Jordi Serra Pueyo Sobrecrecimiento bacteriano intestinal SIBO Hinchazón Distensión abdominal Diarrea Test de hidrógeno y metano Cultivo de aspirado intestinal Antibióticos Iifaximina Probióticos Gastroenterología y Hepatología, 48 (2025) 502216. doi:10.1016/j.gastrohep.2024.502216 The Authors journal Gastroenterología y Hepatología © 2024 The Authors Publicado por Elsevier España, S.L.U. Todos los derechos reservados. 0210-5705 48 2 February 2025 502216 502216 10.1016/j.gastrohep.2024.502216 https://doi.org/10.1016/j.gastrohep.2024.502216 2010-04-23 true 10.1016/j.gastrohep.2024.502216 elsevier.com sciencedirect.com VoR 10.1016/j.gastrohep.2024.502216 noindex 2010-04-23 true sciencedirect.com elsevier.com Elsevier 2025-02-05T11:31:55+05:30 2025-02-05T11:29:17Z 1 https://www.elsevier.com/tdm/tdmrep-policy.json True Acrobat Distiller 24.0 (Windows) True uuid:0956c0f6-ec9a-4d5a-8f35-481a340f45ec uuid:93e214e8-3401-467b-967c-05cdee862bd9 http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 249, 803, 428, 810 Flags: Print Annotation: Subtype: Link Rect: 276, 711, 406, 717 Flags: Print Annotation: Subtype: Link Rect: 516, 627, 545, 656 Flags: Print Annotation: Subtype: Link Rect: 224, 578, 242, 585 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 231, 578, 250, 585 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 392, 578, 411, 585 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 535, 578, 554, 585 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 213, 564, 232, 571 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 221, 564, 240, 571 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 399, 564, 418, 571 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 475, 564, 494, 571 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 223, 551, 242, 557 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 231, 551, 250, 557 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 374, 551, 393, 557 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 511, 551, 529, 557 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 233, 537, 252, 543 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 380, 537, 399, 543 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 388, 537, 406, 543 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 395, 537, 414, 543 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 512, 537, 531, 543 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 520, 537, 539, 543 Flags: Print Destination: 700 Annotation: Subtype: Link Rect: 176, 152, 259, 158 Flags: Print Annotation: Subtype: Link Rect: 91, 130, 271, 136 Flags: Print Annotation: Subtype: Link Rect: 561, 120, 587, 126 Flags: Print Annotation: Subtype: Link Rect: 91, 111, 157, 116 Flags: Print Annotation: Subtype: Link Rect: 157, 111, 172, 116 Flags: Print Annotation: Subtype: Link Rect: 172, 111, 207, 116 Flags: Print Annotation: Subtype: Link Rect: 207, 111, 218, 116 Flags: Print Annotation: Subtype: Link Rect: 218, 111, 230, 115 Flags: Print Annotation: Subtype: Link Rect: 230, 111, 243, 116 Flags: Print Annotation: Subtype: Link Rect: 243, 111, 250, 116 Flags: Print Annotation: Subtype: Link Rect: 250, 111, 258, 116 Flags: Print Annotation: Subtype: Link Rect: 258, 111, 258, 111 Flags: Print Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 324, 658, 352, 664 Flags: Print Annotation: Subtype: Link Rect: 352, 658, 422, 664 Flags: Print Annotation: Subtype: Link Rect: 422, 658, 438, 664 Flags: Print Annotation: Subtype: Link Rect: 438, 658, 476, 664 Flags: Print Annotation: Subtype: Link Rect: 476, 658, 488, 664 Flags: Print Annotation: Subtype: Link Rect: 488, 658, 500, 662 Flags: Print Annotation: Subtype: Link Rect: 500, 658, 513, 664 Flags: Print Annotation: Subtype: Link Rect: 513, 658, 521, 664 Flags: Print Annotation: Subtype: Link Rect: 521, 658, 530, 664 Flags: Print Annotation: Subtype: Link Rect: 530, 658, 530, 658 Flags: Print Annotation: Subtype: Link Rect: 327, 451, 355, 458 Flags: Print Annotation: Subtype: Link Rect: 355, 451, 425, 458 Flags: Print Annotation: Subtype: Link Rect: 425, 451, 441, 458 Flags: Print Annotation: Subtype: Link Rect: 441, 451, 475, 458 Flags: Print Annotation: Subtype: Link Rect: 475, 451, 487, 458 Flags: Print Annotation: Subtype: Link Rect: 487, 451, 499, 456 Flags: Print Annotation: Subtype: Link Rect: 499, 451, 513, 458 Flags: Print Annotation: Subtype: Link Rect: 513, 451, 521, 458 Flags: Print Annotation: Subtype: Link Rect: 521, 451, 529, 458 Flags: Print Annotation: Subtype: Link Rect: 529, 451, 529, 451 Flags: Print Annotation: Subtype: Link Rect: 263, 283, 277, 290 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 242, 184, 250, 191 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 257, 129, 271, 137 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 500, 384, 516, 391 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 472, 318, 480, 325 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 465, 285, 473, 293 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 501, 121, 513, 128 Flags: Print Destination: 267 Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 274, 691, 282, 698 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 539, 548, 551, 556 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 571, 307, 592, 315 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 351, 296, 377, 303 Flags: Print Destination: 42 Annotation: Subtype: Link Rect: 394, 252, 405, 260 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 432, 208, 441, 216 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 457, 165, 469, 172 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 440, 132, 452, 139 Flags: Print Destination: 289 Page: Label: 4 Annotations: Annotation: Subtype: Link Rect: 323, 334, 332, 341 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 279, 290, 291, 298 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 294, 246, 316, 254 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 151, 224, 162, 232 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 222, 137, 233, 144 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 473, 411, 485, 418 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 484, 323, 496, 331 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 392, 246, 403, 254 Flags: Print Destination: 289 Page: Label: 5 Annotations: Annotation: Subtype: Link Rect: 359, 773, 367, 779 Flags: Print Destination: 56 Annotation: Subtype: Link Rect: 293, 471, 302, 479 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 237, 340, 248, 348 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 228, 274, 240, 282 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 310, 110, 322, 117 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 384, 549, 393, 557 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 567, 472, 592, 479 Flags: Print Destination: 56 Annotation: Subtype: Link Rect: 348, 461, 358, 468 Flags: Print Destination: 56 Annotation: Subtype: Link Rect: 356, 461, 368, 469 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 469, 461, 481, 469 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 569, 111, 589, 118 Flags: Print Destination: 289 Page: Label: 6 Annotations: Annotation: Subtype: Link Rect: 222, 570, 234, 578 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 188, 559, 208, 567 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 120, 461, 131, 468 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 170, 428, 182, 435 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 267, 340, 279, 348 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 182, 263, 203, 271 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 188, 252, 200, 260 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 189, 209, 206, 216 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 550, 680, 561, 687 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 533, 581, 545, 588 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 451, 219, 462, 227 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 416, 143, 428, 150 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 559, 110, 571, 117 Flags: Print Destination: 321 Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 132, 591, 144, 599 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 269, 558, 281, 566 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 316, 514, 328, 522 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 138, 383, 150, 390 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 258, 273, 270, 281 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 210, 153, 222, 160 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 468, 746, 480, 753 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 580, 636, 592, 644 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 369, 581, 381, 589 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 450, 241, 462, 249 Flags: Print Destination: 321 Page: Label: 8 Annotations: Annotation: Subtype: Link Rect: 320, 691, 332, 698 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 218, 603, 226, 611 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 100, 526, 112, 534 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 272, 472, 284, 479 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 239, 450, 251, 457 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 366, 731, 378, 739 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 418, 665, 444, 672 Flags: Print Destination: 117 Annotation: Subtype: Link Rect: 441, 665, 451, 672 Flags: Print Destination: 117 Annotation: Subtype: Link Rect: 526, 654, 538, 662 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 415, 545, 427, 552 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 507, 501, 519, 509 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 565, 369, 577, 377 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 405, 271, 417, 278 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 469, 150, 491, 158 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 502, 139, 514, 147 Flags: Print Destination: 321 Page: Label: 9 Annotations: Annotation: Subtype: Link Rect: 240, 134, 248, 145 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 275, 450, 281, 458 Flags: Print Destination: 125 Annotation: Subtype: Link Rect: 372, 134, 379, 145 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 384, 466, 390, 474 Flags: Print Destination: 125 Annotation: Subtype: Link Rect: 460, 134, 467, 145 Flags: Print Destination: 289 Rotate: 90 Page: Label: 10 Annotations: Annotation: Subtype: Link Rect: 235, 134, 243, 145 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 247, 459, 254, 467 Flags: Print Destination: 125 Annotation: Subtype: Link Rect: 367, 134, 374, 145 Flags: Print Destination: 321 Rotate: 90 Page: Label: 11 Annotations: Annotation: Subtype: Link Rect: 408, 773, 428, 781 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 320, 425, 332, 433 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 145, 359, 156, 367 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 180, 250, 192, 257 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 246, 140, 258, 148 Flags: Print Destination: 321 Annotation: Subtype: Link Rect: 549, 545, 575, 552 Flags: Print Destination: 131 Annotation: Subtype: Link Rect: 576, 545, 586, 552 Flags: Print Destination: 131 Annotation: Subtype: Link Rect: 404, 524, 424, 531 Flags: Print Destination: 289 Annotation: Subtype: Link Rect: 577, 502, 589, 509 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 402, 392, 413, 400 Flags: Print Destination: 444 Page: Label: 12 Annotations: Annotation: Subtype: Link Rect: 308, 756, 320, 763 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 134, 679, 160, 686 Flags: Print Destination: 267 Annotation: Subtype: Link Rect: 320, 346, 332, 354 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 306, 302, 318, 310 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 115, 203, 126, 211 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 500, 724, 512, 731 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 577, 614, 589, 622 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 444, 537, 455, 545 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 393, 504, 404, 512 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 418, 241, 430, 249 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 558, 198, 570, 205 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 564, 143, 576, 150 Flags: Print Destination: 444 Page: Label: 13 Annotations: Annotation: Subtype: Link Rect: 179, 711, 191, 719 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 267, 646, 279, 653 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 130, 503, 142, 511 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 194, 437, 206, 445 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 266, 181, 277, 189 Flags: Print Destination: 444 Annotation: Subtype: Link Rect: 401, 647, 413, 655 Flags: Print Destination: 444 Page: Label: 14 Page: Label: 15 Page: Label: 16 Page: Label: 17 Page: Label: 18 Page: Label: 19 Page: Label: 20 Page: Label: 21 Page: Label: 22 Annotations: Annotation: Subtype: Link Rect: 148, 425, 173, 432 Flags: Print Destination: 168 Annotation: Subtype: Link Rect: 171, 425, 181, 431 Flags: Print Destination: 168 Annotation: Subtype: Link Rect: 105, 194, 279, 199 Flags: Print Annotation: Subtype: Link Rect: 211, 164, 330, 170 Flags: Print Annotation: Subtype: Link Rect: 105, 154, 172, 159 Flags: Print Annotation: Subtype: Link Rect: 105, 124, 264, 130 Flags: Print Annotation: Subtype: Link Rect: 429, 748, 570, 753 Flags: Print Annotation: Subtype: Link Rect: 362, 708, 540, 714 Flags: Print Annotation: Subtype: Link Rect: 362, 668, 525, 674 Flags: Print Annotation: Subtype: Link Rect: 362, 628, 536, 634 Flags: Print Annotation: Subtype: Link Rect: 362, 568, 532, 574 Flags: Print Annotation: Subtype: Link Rect: 362, 518, 532, 524 Flags: Print Annotation: Subtype: Link Rect: 362, 479, 532, 484 Flags: Print Annotation: Subtype: Link Rect: 362, 379, 503, 385 Flags: Print Annotation: Subtype: Link Rect: 362, 339, 536, 345 Flags: Print Annotation: Subtype: Link Rect: 362, 299, 547, 305 Flags: Print Annotation: Subtype: Link Rect: 362, 249, 528, 255 Flags: Print Annotation: Subtype: Link Rect: 362, 200, 532, 206 Flags: Print Annotation: Subtype: Link Rect: 362, 140, 532, 146 Flags: Print Page: Label: 23 Annotations: Annotation: Subtype: Link Rect: 105, 749, 269, 754 Flags: Print Annotation: Subtype: Link Rect: 105, 699, 269, 705 Flags: Print Annotation: Subtype: Link Rect: 105, 639, 263, 645 Flags: Print Annotation: Subtype: Link Rect: 105, 589, 271, 595 Flags: Print Annotation: Subtype: Link Rect: 105, 539, 275, 545 Flags: Print Annotation: Subtype: Link Rect: 105, 499, 274, 505 Flags: Print Annotation: Subtype: Link Rect: 105, 460, 290, 466 Flags: Print Annotation: Subtype: Link Rect: 105, 420, 271, 426 Flags: Print Annotation: Subtype: Link Rect: 105, 370, 290, 376 Flags: Print Annotation: Subtype: Link Rect: 105, 330, 275, 336 Flags: Print Annotation: Subtype: Link Rect: 105, 280, 279, 286 Flags: Print Annotation: Subtype: Link Rect: 105, 230, 290, 236 Flags: Print Annotation: Subtype: Link Rect: 105, 191, 268, 197 Flags: Print Annotation: Subtype: Link Rect: 105, 141, 240, 147 Flags: Print Annotation: Subtype: Link Rect: 362, 767, 521, 773 Flags: Print Annotation: Subtype: Link Rect: 420, 728, 584, 734 Flags: Print Annotation: Subtype: Link Rect: 362, 688, 532, 694 Flags: Print Annotation: Subtype: Link Rect: 362, 648, 532, 654 Flags: Print Annotation: Subtype: Link Rect: 362, 588, 547, 594 Flags: Print Annotation: Subtype: Link Rect: 362, 528, 547, 534 Flags: Print Annotation: Subtype: Link Rect: 362, 489, 562, 494 Flags: Print Annotation: Subtype: Link Rect: 362, 439, 497, 445 Flags: Print Annotation: Subtype: Link Rect: 362, 399, 532, 405 Flags: Print Annotation: Subtype: Link Rect: 362, 349, 534, 355 Flags: Print Annotation: Subtype: Link Rect: 362, 299, 506, 305 Flags: Print Annotation: Subtype: Link Rect: 362, 249, 536, 255 Flags: Print Annotation: Subtype: Link Rect: 362, 200, 551, 206 Flags: Print Annotation: Subtype: Link Rect: 362, 160, 527, 166 Flags: Print Annotation: Subtype: Link Rect: 362, 110, 547, 116 Flags: Print Page: Label: 24 Annotations: Annotation: Subtype: Link Rect: 105, 739, 297, 744 Flags: Print Annotation: Subtype: Link Rect: 105, 699, 279, 705 Flags: Print Annotation: Subtype: Link Rect: 105, 649, 271, 655 Flags: Print Annotation: Subtype: Link Rect: 105, 609, 271, 615 Flags: Print Annotation: Subtype: Link Rect: 105, 559, 275, 565 Flags: Print Annotation: Subtype: Link Rect: 175, 509, 320, 515 Flags: Print Annotation: Subtype: Link Rect: 167, 470, 302, 475 Flags: Print Annotation: Subtype: Link Rect: 105, 410, 283, 416 Flags: Print Annotation: Subtype: Link Rect: 160, 370, 330, 376 Flags: Print Annotation: Subtype: Link Rect: 105, 360, 138, 366 Flags: Print Annotation: Subtype: Link Rect: 105, 310, 244, 316 Flags: Print Annotation: Subtype: Link Rect: 105, 260, 269, 266 Flags: Print Annotation: Subtype: Link Rect: 158, 221, 300, 226 Flags: Print Annotation: Subtype: Link Rect: 105, 181, 275, 187 Flags: Print Annotation: Subtype: Link Rect: 172, 141, 320, 147 Flags: Print Annotation: Subtype: Link Rect: 362, 767, 531, 773 Flags: Print Annotation: Subtype: Link Rect: 362, 728, 497, 734 Flags: Print Annotation: Subtype: Link Rect: 362, 678, 497, 684 Flags: Print Annotation: Subtype: Link Rect: 424, 638, 559, 644 Flags: Print Annotation: Subtype: Link Rect: 362, 588, 547, 594 Flags: Print Annotation: Subtype: Link Rect: 362, 528, 554, 534 Flags: Print Annotation: Subtype: Link Rect: 362, 479, 554, 484 Flags: Print Annotation: Subtype: Link Rect: 362, 429, 554, 435 Flags: Print Annotation: Subtype: Link Rect: 362, 379, 544, 385 Flags: Print Annotation: Subtype: Link Rect: 363, 369, 396, 375 Annotation: Subtype: Link Rect: 400, 368, 410, 375 Annotation: Subtype: Link Rect: 414, 369, 444, 375 Annotation: Subtype: Link Rect: 447, 368, 455, 375 Annotation: Subtype: Link Rect: 459, 367, 496, 375 Annotation: Subtype: Link Rect: 499, 368, 505, 375 Annotation: Subtype: Link Rect: 509, 367, 530, 375 Annotation: Subtype: Link Rect: 533, 369, 537, 375 Annotation: Subtype: Link Rect: 537, 368, 538, 370 Annotation: Subtype: Link Rect: 543, 369, 547, 375 Annotation: Subtype: Link Rect: 547, 369, 576, 375 Annotation: Subtype: Link Rect: 580, 368, 586, 375 Annotation: Subtype: Link Rect: 363, 359, 367, 365 Annotation: Subtype: Link Rect: 367, 359, 383, 365 Annotation: Subtype: Link Rect: 387, 358, 394, 365 Annotation: Subtype: Link Rect: 399, 359, 406, 364 Annotation: Subtype: Link Rect: 411, 359, 419, 365 Annotation: Subtype: Link Rect: 424, 359, 458, 365 Annotation: Subtype: Link Rect: 463, 357, 490, 365 Annotation: Subtype: Link Rect: 494, 359, 500, 365 Annotation: Subtype: Link Rect: 504, 359, 522, 365 Annotation: Subtype: Link Rect: 527, 359, 560, 365 Annotation: Subtype: Link Rect: 565, 359, 587, 365 Annotation: Subtype: Link Rect: 363, 349, 374, 355 Annotation: Subtype: Link Rect: 378, 347, 420, 355 Annotation: Subtype: Link Rect: 425, 349, 456, 355 Annotation: Subtype: Link Rect: 459, 349, 481, 353 Annotation: Subtype: Link Rect: 485, 349, 538, 355 Annotation: Subtype: Link Rect: 543, 349, 554, 355 Annotation: Subtype: Link Rect: 558, 349, 562, 355 Annotation: Subtype: Link Rect: 562, 349, 570, 353 Annotation: Subtype: Link Rect: 573, 349, 587, 355 Annotation: Subtype: Link Rect: 363, 339, 367, 345 Annotation: Subtype: Link Rect: 367, 339, 399, 345 Annotation: Subtype: Link Rect: 402, 339, 414, 345 Annotation: Subtype: Link Rect: 418, 338, 459, 345 Annotation: Subtype: Link Rect: 461, 341, 463, 342 Annotation: Subtype: Link Rect: 462, 341, 464, 342 Annotation: Subtype: Link Rect: 463, 341, 465, 342 Annotation: Subtype: Link Rect: 466, 339, 472, 345 Annotation: Subtype: Link Rect: 476, 339, 494, 345 Annotation: Subtype: Link Rect: 498, 339, 533, 345 Annotation: Subtype: Link Rect: 362, 289, 503, 295 Flags: Print Annotation: Subtype: Link Rect: 424, 239, 559, 245 Flags: Print Annotation: Subtype: Link Rect: 363, 230, 367, 235 Annotation: Subtype: Link Rect: 366, 229, 387, 235 Annotation: Subtype: Link Rect: 389, 228, 397, 235 Annotation: Subtype: Link Rect: 401, 230, 405, 235 Annotation: Subtype: Link Rect: 405, 229, 426, 234 Annotation: Subtype: Link Rect: 429, 228, 434, 235 Annotation: Subtype: Link Rect: 439, 229, 475, 235 Annotation: Subtype: Link Rect: 478, 228, 485, 235 Annotation: Subtype: Link Rect: 489, 229, 512, 235 Annotation: Subtype: Link Rect: 516, 228, 521, 235 Annotation: Subtype: Link Rect: 525, 229, 552, 235 Annotation: Subtype: Link Rect: 556, 228, 562, 235 Annotation: Subtype: Link Rect: 566, 229, 587, 235 Annotation: Subtype: Link Rect: 362, 218, 369, 225 Annotation: Subtype: Link Rect: 373, 219, 380, 225 Annotation: Subtype: Link Rect: 382, 219, 391, 225 Annotation: Subtype: Link Rect: 394, 220, 398, 225 Annotation: Subtype: Link Rect: 399, 219, 433, 225 Annotation: Subtype: Link Rect: 435, 219, 447, 225 Annotation: Subtype: Link Rect: 451, 218, 486, 225 Annotation: Subtype: Link Rect: 489, 219, 496, 225 Annotation: Subtype: Link Rect: 499, 219, 517, 225 Annotation: Subtype: Link Rect: 520, 219, 553, 225 Annotation: Subtype: Link Rect: 556, 219, 587, 225 Annotation: Subtype: Link Rect: 363, 208, 402, 215 Annotation: Subtype: Link Rect: 407, 210, 413, 215 Annotation: Subtype: Link Rect: 418, 208, 448, 215 Annotation: Subtype: Link Rect: 453, 210, 482, 215 Annotation: Subtype: Link Rect: 487, 208, 515, 215 Annotation: Subtype: Link Rect: 520, 210, 535, 215 Annotation: Subtype: Link Rect: 540, 208, 587, 215 Annotation: Subtype: Link Rect: 363, 200, 373, 206 Annotation: Subtype: Link Rect: 376, 198, 413, 205 Annotation: Subtype: Link Rect: 417, 200, 429, 206 Annotation: Subtype: Link Rect: 433, 198, 445, 205 Annotation: Subtype: Link Rect: 448, 200, 487, 206 Annotation: Subtype: Link Rect: 491, 198, 518, 205 Annotation: Subtype: Link Rect: 521, 200, 525, 205 Annotation: Subtype: Link Rect: 528, 198, 546, 206 Annotation: Subtype: Link Rect: 549, 200, 575, 205 Annotation: Subtype: Link Rect: 576, 202, 578, 202 Annotation: Subtype: Link Rect: 577, 202, 579, 202 Annotation: Subtype: Link Rect: 578, 202, 579, 202 Annotation: Subtype: Link Rect: 580, 200, 586, 205 Annotation: Subtype: Link Rect: 363, 188, 380, 195 Annotation: Subtype: Link Rect: 383, 190, 399, 195 Annotation: Subtype: Link Rect: 402, 190, 415, 195 Annotation: Subtype: Link Rect: 418, 190, 423, 195 Annotation: Subtype: Link Rect: 427, 190, 446, 195 Annotation: Subtype: Link Rect: 449, 190, 485, 195 Annotation: Subtype: Link Rect: 362, 150, 532, 156 Flags: Print Annotation: Subtype: Link Rect: 362, 110, 554, 116 Flags: Print Page: Label: 25 Annotations: Annotation: Subtype: Link Rect: 105, 739, 271, 744 Flags: Print Annotation: Subtype: Link Rect: 105, 699, 271, 705 Flags: Print Annotation: Subtype: Link Rect: 105, 649, 290, 655 Flags: Print Annotation: Subtype: Link Rect: 105, 609, 297, 615 Flags: Print Annotation: Subtype: Link Rect: 105, 569, 253, 575 Flags: Print Annotation: Subtype: Link Rect: 167, 529, 304, 535 Flags: Print Annotation: Subtype: Link Rect: 105, 480, 275, 485 Flags: Print Annotation: Subtype: Link Rect: 105, 430, 247, 436 Flags: Print Annotation: Subtype: Link Rect: 105, 370, 240, 376 Flags: Print Annotation: Subtype: Link Rect: 105, 310, 271, 316 Flags: Print Annotation: Subtype: Link Rect: 105, 250, 255, 256 Flags: Print Annotation: Subtype: Link Rect: 429, 768, 566, 774 Flags: Print Annotation: Subtype: Link Rect: 362, 719, 547, 725 Flags: Print Annotation: Subtype: Link Rect: 362, 659, 532, 665 Flags: Print Annotation: Subtype: Link Rect: 362, 599, 547, 605 Flags: Print Annotation: Subtype: Link Rect: 411, 539, 558, 545 Flags: Print Annotation: Subtype: Link Rect: 362, 480, 530, 485 Flags: Print Annotation: Subtype: Link Rect: 362, 420, 532, 426 Flags: Print Annotation: Subtype: Link Rect: 362, 370, 528, 376 Flags: Print Annotation: Subtype: Link Rect: 362, 330, 528, 336 Flags: Print Annotation: Subtype: Link Rect: 362, 270, 548, 276 Flags: Print Annotation: Subtype: Link Rect: 416, 230, 573, 236 Flags: Print Checksum: b7623df6 Type: CRC32 Checksum: c62d427b5850e5ce91edb3d84d2c1331 Type: MD5 Checksum: a1ca7edf6f3c233b94530ba076fa2dace23196ec Type: SHA-1 Checksum: 56b758bff9f3cf09145db48d324ab57ee6ffc3310c15e40229033c26985bafa8 Type: SHA-256