5baf7fd67693659350349a11ad734307 molcelpro_a2025v24n7art101008.pdf fc46c98fd946428ed00782030f84d1240b76c087 molcelpro_a2025v24n7art101008.pdf 3894a5698217670a3dbb236427623fc235b7d66ba5d72e3f4d970fbbaf7bf4eb molcelpro_a2025v24n7art101008.pdf Title: Closer Peptide Repertoire Similarity of HLA-B∗14:03 and HLA-B∗27:05 Sheds Light on Ankylosing Spondylitis Susceptibility Subject: Mol Cell Proteomics, 24 (2025) 101008. doi:10.1016/j.mcpro.2025.101008 Author: Laura Cobos-Figueroa Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Sat Aug 2 17:51:05 2025 CEST ModDate: Thu Aug 7 16:59:47 2025 CEST Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 19 Encrypted: no Page size: 593.972 x 782.986 pts Page rot: 0 File size: 2752321 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- NHOAEO+AdvOTd1f5cc91.B Type 1C WinAnsi yes yes no 1145 0 NHOAFP+AdvOT7fe89a09 Type 1C WinAnsi yes yes no 1147 0 NHOAGA+Advstixtexrm Type 1C Custom yes yes yes 1152 0 NHOAHB+Arial-BoldMT Type 1C WinAnsi yes yes no 1154 0 NHOAIB+ArialMT Type 1C WinAnsi yes yes no 1158 0 NHOAPA+AdvOT7fe89a09+fb Type 1C Custom yes yes yes 1171 0 NHOAPB+AdvOT7fe89a09+20 Type 1C WinAnsi yes yes no 1174 0 NHOAPC+AdvOTfadd598a.BI Type 1C WinAnsi yes yes no 1165 0 NHOBAC+AdvOT5136ebae Type 1C WinAnsi yes yes no 1172 0 NHOBIA+AdvstixtSym Type 1C Custom yes yes yes 795 0 NHOBKB+AdvOTd1f5cc91.B+fb Type 1C Custom yes yes yes 812 0 NHOBNB+AdvOT945f1ecc.I Type 1C WinAnsi yes yes no 806 0 NHOBNC+AdvOT602ae986 Type 1C WinAnsi yes yes no 809 0 NHOBJB+AdvOTd1f5cc91.B+20 Type 1C WinAnsi yes yes no 815 0 NHOBOD+AdvOTc4f305bd.I Type 1C WinAnsi yes yes no 820 0 NHOBOE+AdvOTb0c9bf5d+03 Type 1C Custom yes yes yes 818 0 NHOIAP+AdvOTc4f305bd.I+fb Type 1C Custom yes yes yes 830 0 NHOKFC+AdvOTc4f305bd.I+20 Type 1C WinAnsi yes yes no 873 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-01-31 03:10:16 CET RepresentationInformation: molcelpro_a2025v24n7art101008.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-01-30 06:06:53 CET Size: 2752321 Format: PDF Version: 1.7 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ErrorMessage: Invalid indirect destination - referenced object 'cor1' cannot be found ID: PDF-HUL-149 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'cor1' cannot be found ID: PDF-HUL-122 Offset: 2713413 MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 1457 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Closer Peptide Repertoire Similarity of HLA-B∗14:03 and HLA-B∗27:05 Sheds Light on Ankylosing Spondylitis Susceptibility Destination: titlink1 Children: Item: Title: Experimental Procedures Destination: flink1 Children: Item: Title: Cell Lines Destination: slink1 Item: Title: Isolation of HLA-B∗14:02-, B∗14:03-, and B∗27:05-bound Peptides Destination: slink2 Item: Title: Mass Spectrometry Analysis Destination: slink3 Item: Title: Analysis of HLA-B∗14:02-, B∗14:03-, and B∗27:05-bound Peptides Destination: slink4 Item: Title: Experimental Design and Statistical Rationale Destination: slink5 Item: Title: Results Destination: flink2 Children: Item: Title: Highly Overlapping Peptide Repertoire Among AS-Associated HLA Alleles Destination: slink6 Item: Title: Different Size of the Peptides Bound to HLA-B∗27:05, -B∗14:02, and -B∗14:03 Destination: slink7 Item: Title: Differences in Sidechain Composition Between the B∗14 and B∗27:05-Bound Peptide Repertoires Destination: slink8 Item: Title: The Single Amino Acid Difference Between the Sequences of HLA-B∗14:02 and HLA-B∗14:03 Could Affect Amino Acid Frequencies a ... Destination: slink9 Item: Title: Differential Characteristics Between Common and Specific Peptide Ligands Destination: slink10 Item: Title: Common Peptides are More Abundant in the Eluates Than Specific Peptides Destination: slink11 Item: Title: Differential Presentation of HLA-Derived Peptides Destination: slink12 Item: Title: Overlap Between B∗14 and B∗27 Subtypes Destination: slink13 Item: Title: Discussion Destination: flink3 Item: Title: Data Availability Destination: flink4 Item: Title: Supplemental Data Destination: flink5 Item: Title: Author Contributions Destination: flink6 Item: Title: Funding and Additional Information Destination: flink7 Item: Title: References Destination: blink1 Info: Title: Closer Peptide Repertoire Similarity of HLA-B∗14:03 and HLA-B∗27:05 Sheds Light on Ankylosing Spondylitis Susceptibility Author: Laura Cobos-Figueroa Subject: Mol Cell Proteomics, 24 (2025) 101008. doi:10.1016/j.mcpro.2025.101008 Creator: Elsevier Producer: Acrobat Distiller 8.1.0 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FontDescriptor: FontName: NHOAEO+AdvOTd1f5cc91.B Flags: Nonsymbolic FontBBox: -52, -208, 937, 968 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NHOAFP+AdvOT7fe89a09 FontSubset: true FirstChar: 37 LastChar: 252 FontDescriptor: FontName: NHOAFP+AdvOT7fe89a09 Flags: Nonsymbolic FontBBox: -52, -208, 906, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NHOBIA+AdvstixtSym FontSubset: true FirstChar: 1 LastChar: 4 FontDescriptor: FontName: NHOBIA+AdvstixtSym Flags: Symbolic FontBBox: -20, -1114, 1135, 822 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: NHOIAP+AdvOTc4f305bd.I+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: NHOIAP+AdvOTc4f305bd.I+fb Flags: Symbolic FontBBox: 19, 0, 520, 718 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true XMP: application/pdf doi:10.1016/j.mcpro.2025.101008 Closer Peptide Repertoire Similarity of HLA-B∗14:03 and HLA-B∗27:05 Sheds Light on Ankylosing Spondylitis Susceptibility Laura Cobos-Figueroa Javier Robles-Parrado Elisenda Alari-Pahissa Begoña Galocha Carmen Mir Ana Pintor-Poveda Eilon Barnea Arie Admon Pilar Lauzurica Elena Lorente HLA-B∗27 HLA-B∗14 ankylosing spondylitis peptide repertoires mass spectrometry arthritogenic peptides cross-reactivity Mol Cell Proteomics, 24 (2025) 101008. doi:10.1016/j.mcpro.2025.101008 The Authors journal Mol Cell Proteomics © 2025 The Authors. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology. 1535-9476 24 7 July 2025 101008 101008 10.1016/j.mcpro.2025.101008 https://doi.org/10.1016/j.mcpro.2025.101008 2010-04-23 true 10.1016/j.mcpro.2025.101008 elsevier.com sciencedirect.com VoR 7.0.1 10.1016/j.mcpro.2025.101008 noindex 2010-04-23 true sciencedirect.com elsevier.com Elsevier 2025-08-02T21:21:05+05:30 2025-08-07T20:29:47+05:30 2025-08-07T20:29:47+05:30 True 1 https://www.elsevier.com/tdm/tdmrep-policy.json Acrobat Distiller 8.1.0 (Windows) uuid:032e99d1-e753-4064-868c-eeb414dfca32 uuid:45310e0b-b485-46c7-854b-a6f1212fc8fe http://creativecommons.org/licenses/by/4.0/ Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 45, 537, 128, 548 Annotation: Subtype: Link Rect: 400, 40, 536, 50 Annotation: Subtype: Link Rect: 45, 29, 120, 39 Annotation: Subtype: Link Rect: 45, 18, 252, 28 Annotation: Subtype: Link Rect: 525, 741, 547, 763 Page: Label: 2 Page: Label: 3 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634 Annotation: Subtype: Link Rect: 65, 618, 291, 625 Annotation: Subtype: Link Rect: 65, 609, 197, 616 Annotation: Subtype: Link Rect: 316, 708, 403, 715 Annotation: Subtype: Link Rect: 406, 708, 548, 715 Annotation: Subtype: Link Rect: 322, 699, 548, 706 Annotation: Subtype: Link Rect: 322, 690, 548, 697 Annotation: Subtype: Link Rect: 316, 681, 548, 688 Annotation: Subtype: Link Rect: 322, 672, 548, 679 Annotation: Subtype: Link Rect: 322, 663, 444, 670 Annotation: Subtype: Link Rect: 316, 654, 548, 661 Annotation: Subtype: Link Rect: 322, 645, 548, 652 Annotation: Subtype: Link Rect: 322, 636, 354, 643 Annotation: Subtype: Link Rect: 316, 627, 548, 634 Annotation: Subtype: Link Rect: 322, 618, 548, 625 Annotation: Subtype: Link Rect: 322, 609, 475, 616 Checksum: 9551d076 Type: CRC32 Checksum: 5baf7fd67693659350349a11ad734307 Type: MD5 Checksum: fc46c98fd946428ed00782030f84d1240b76c087 Type: SHA-1 Checksum: 3894a5698217670a3dbb236427623fc235b7d66ba5d72e3f4d970fbbaf7bf4eb Type: SHA-256