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UseOutlines Outlines: Item: Title: The Down Alzheimer Barcelona Neuroimaging Initiative (DABNI) and its contributions to understanding Alzheimer’s disease in Down syndrome: A decade of discovery Destination: chapter..1 Children: Item: Title: Abstract Destination: section*.2 Item: Title: 1 | BACKGROUND Destination: section..1.1 Item: Title: 2 | METHODS Destination: section..1.2 Children: Item: Title: 2.1 | The Alzheimer-down Unit Destination: subsection..1.2.1 Item: Title: 2.2 | Participant recruitment Destination: subsection..1.2.2 Item: Title: 2.3 | DABNI cohort-General procedures Destination: subsection..1.2.3 Children: Item: Title: 2.3.1 | Prebaseline phone call Destination: subsubsection..1.2.3.1 Item: Title: 2.3.2 | Clinic medical evaluation Destination: subsubsection..1.2.3.2 Item: Title: 2.3.3 | ID assessment Destination: subsubsection..1.2.3.3 Item: Title: 2.3.4 | Neuropsychological evaluation Destination: subsubsection..1.2.3.4 Item: Title: 2.3.5 | Diagnostic process Destination: subsubsection..1.2.3.5 Item: Title: 2.3.6 | Nursing evaluation Destination: subsubsection..1.2.3.6 Item: Title: 2.3.7 | Postdiagnostic orientation visits Destination: subsubsection..1.2.3.7 Item: Title: 2.3.8 | CSF and biomarker assessment Destination: subsubsection..1.2.3.8 Item: Title: 2.3.9 | Blood and DNA extraction Destination: subsubsection..1.2.3.9 Item: Title: 2.3.10 | Structural, diffusion, and functional magnetic resonance imaging (MRI) Destination: subsubsection..1.2.3.10 Item: Title: 2.3.11 | Nuclear medicine imaging Destination: subsubsection..1.2.3.11 Item: Title: 2.3.12 | Sleep evaluation Destination: subsubsection..1.2.3.12 Item: Title: 2.3.13 | EEG Destination: subsubsection..1.2.3.13 Item: Title: 2.3.14 | Neuropathology Destination: subsubsection..1.2.3.14 Item: Title: 2.3.15 | Data integration Destination: subsubsection..1.2.3.15 Item: Title: 2.3.16 | Clinical trials and international studies Destination: subsubsection..1.2.3.16 Item: Title: 2.3.17 | Ethical aspects Destination: subsubsection..1.2.3.17 Item: Title: 3 | RESULTS Destination: section..1.3 Children: Item: Title: 3.1 | Clinical studies Destination: subsection..1.3.1 Item: Title: 3.2 | Sleep and EEG studies Destination: subsection..1.3.2 Item: Title: 3.3 | Blood, CSF, genetics, and post mortem studies Destination: subsection..1.3.3 Item: Title: 3.4 | Neuroimaging studies Destination: subsection..1.3.4 Item: Title: 3.5 | Natural history Destination: subsection..1.3.5 Item: Title: 3.6 | International collaborations Destination: subsection..1.3.6 Item: Title: 3.7 | Clinical trials Destination: subsection..1.3.7 Item: Title: 4 | DISCUSSION Destination: section..1.4 Item: Title: AFFILIATIONS Destination: section*.4 Item: Title: ACKNOWLEDGMENTS Destination: section*.6 Item: Title: CONFLICT OF INTEREST STATEMENT Destination: section*.8 Item: Title: ETHICS STATEMENT Destination: section*.10 Item: Title: ORCID Destination: section*.12 Item: Title: REFERENCES Destination: section*.14 Item: Title: SUPPORTING INFORMATION Destination: section*.16 Info: Title: The Down Alzheimer Barcelona Neuroimaging Initiative (DABNI) and its contributions to understanding Alzheimer's disease in Down syndrome: A decade of discovery Author: Subject: Keywords: Creator: LaTeX with hyperref package Producer: Acrobat Distiller 10.0.0 (Windows) CreationDate: Tue Jun 17 12:43:09 CEST 2025 ModDate: Tue Jun 17 12:43:47 CEST 2025 ID: 0xaf070a4c21b3da15f06b68b7be109f11, 0xdb4deaee4ad73a6d3641fcc4ad6ecd4f Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2100 ImageHeight: 1404 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 122 ImageHeight: 929 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 121 ImageHeight: 103 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