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Title:           Transferability of European-derived Alzheimer’s disease polygenic risk scores across multiancestry populations
Subject:         Nature Genetics, doi:10.1038/s41588-025-02227-w
Keywords:        
Author:          Aude Nicolas
Creator:         Springer
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     Item: 
      Title: Transferability of European-derived Alzheimer’s disease polygenic risk scores across multiancestry populations
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        Title: Online content
       Item: 
        Title: Fig. 1 Associations between the various PGSs and the risk of developing AD as a function of APOE status (25,782 AD cases and 3㔀Ⰰ㈀㠀　 挀漀渀琀爀漀氀猀⸩㸾൥湤潢樍㄰㔵‰扪഼㰯䐨獰物湧敲湡瑵牥彮慴来湥瑟㈲㈷⹩湤携䅮捨潲″㨱㘲
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        Title: Fig. 2 Association of PGSALZ with Aβ42 and p-tau in cerebrospinal fluid.
       Item: 
        Title: Fig. 3 Association of PGSALZ across multiancestry populations.
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        Title: Fig. 4 Comparison of the association of PGSALZ or PRS (excluding the APOE region) with the AD risk and the corresponding predictive values (adjusted Nagelkerke R2 and liability R2).
       Item: 
        Title: Fig. 5 Association of PRS (including the APOE region) with the AD risk and the corresponding predictive values (adjusted Nage氀欀攀爀欀攀 刀㈀ 愀渀搀 氀椀愀戀椀氀椀琀礀 刀㈀⸩㸾൥湤潢樍㄰㐷‰扪഼㰯䐨獰物湧敲湡瑵牥彮慴来湥瑟㈲㈷⹩湤携䅮捨潲‷㨱㘶
       Item: 
        Title: Fig. 6 Association of PGSALZ or PRSCOMB (excluding the APOE region) with AD, AD and related dementia (ADRD) and dementia in MVP, and the corresponding predictive values (adjusted Nagelkerke R2 and liability R2).
       Item: 
        Title: Extended Data Fig. 1 Association of PGSALZ with the risk of developing AD (a) in 17 European countries and (b) in Men and Women.
       Item: 
        Title: Extended Data Fig. 2 Associations between (a) PGSALZ or (b) PGSALZ adjusted for APOE and age at onset of AD in European countries.
       Item: 
        Title: Extended Data Fig. 3 Distribution and association of APOE ε2/ε3/ε4 alleles with AD risk worldwide.
       Item: 
        Title: Extended Data Fig. 4 Association between (a) PGSALZ or (b) PGSALZ (adjusted for APOE) and age at onset of AD in multi-ancestry populations.
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    Title: Transferability of European-derived Alzheimer’s disease polygenic risk scores across multiancestry populations
    Author: Aude Nicolas
    Subject: Nature Genetics, doi:10.1038/s41588-025-02227-w
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    Creator: Springer
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               <rdf:li>Aude Nicolas</rdf:li>
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