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Destination: mk:title Children: Item: Title: 1 Introduction Destination: mk:H1_1 Item: Title: 2 Materials and methods Destination: mk:H1_2 Children: Item: Title: 2.1 Participants Destination: mk:H2_1 Item: Title: 2.2 Procedure Destination: mk:H2_2 Children: Item: Title: 2.2.1 Biometric assessment and blood sampling Destination: mk:H3_3 Item: Title: 2.2.2 Clinical assessment Destination: mk:H3_4 Item: Title: 2.2.3 Cognitive assessment Destination: mk:H3_5 Item: Title: 2.3 Blood protein analysis Destination: mk:H2_6 Item: Title: 2.4 Statistical analysis Destination: mk:H2_7 Children: Item: Title: 2.4.1 Sample description Destination: mk:H3_8 Item: Title: 2.4.2 Plasma protein profiles Destination: mk:H3_9 Item: Title: 2.4.3 Hierarchical clustering of protein expression and pathway enrichment analysis Destination: mk:H3_10 Item: Title: 2.4.4 Associations between protein expression and psychotic symptoms Destination: mk:H3_11 Item: Title: 2.4.5 Associations between protein expression and cognitive performance Destination: mk:H3_12 Item: Title: 3 Results Destination: mk:H1_3 Children: Item: Title: 3.1 Sample description Destination: mk:H2_13 Item: Title: 3.2 Plasma protein profiles Destination: mk:H2_14 Item: Title: 3.3 Hierarchical clustering and biological functions Destination: mk:H2_15 Item: Title: 3.4 Associations between protein expression and psychotic symptoms Destination: mk:H2_16 Item: Title: 3.5 Associations between protein expression and cognitive performance Destination: mk:H2_17 Item: Title: 4 Discussion Destination: mk:H1_4 Children: Item: Title: 4.1 Plasma protein profiles, hierarchical clustering of protein expression and biological functions Destination: mk:H2_18 Item: Title: 4.2 Association of protein expression with symptom severity Destination: mk:H2_19 Item: Title: 4.3 Association of protein expression with cognitive performance Destination: mk:H2_20 Item: Title: 4.4 Study limitations Destination: mk:H2_21 Item: Title: 4.5 Final discussion Destination: mk:H2_22 Item: Title: 5 Conclusions Destination: mk:H1_5 Item: Title: CRediT authorship contribution statement Destination: mk:H1_6 Item: Title: Funding sources Destination: mk:H1_7 Item: Title: Declaration of competing interest Destination: mk:HH1_2 Item: Title: Acknowledgments Destination: mk:HH1_3 Item: Title: Appendix A Supplementary data Destination: mk:H1_8 Item: Title: Data availability Destination: datalink4 Item: Title: References Destination: mk:HH2_1 Info: Title: Plasma profiles of neurology-related proteins in at-risk mental state and first-episode psychosis: Associations with psychotic symptoms and cognitive performance Author: Martí Llaurador-Coll Subject: Brain, Behavior, & Immunity - Health, 50 (2025) 101134. doi:10.1016/j.bbih.2025.101134 Keywords: Psychosis,First-episode psychosis,At-risk mental state,Proximity extension assay,Cognition,Biomarkers,Protein,Plasma Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Fri Dec 12 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Brain, Behavior, & Immunity - Health, 50 (2025) 101134. doi:10.1016/j.bbih.2025.101134 Psychosis First-episode psychosis At-risk mental state Proximity extension assay Cognition Biomarkers Protein Plasma Plasma profiles of neurology-related proteins in at-risk mental state and first-episode psychosis: Associations with psychotic symptoms and cognitive performance Martí Llaurador-Coll Itziar Montalvo Francesc Estrada Vanessa Sánchez-Gistau Henrik Zetterberg Javier Labad Andrea L. 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