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DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: Reprogramming autoimmunity: inducing antigen-specific tolerance via apoptotic mimicry in an experimental model of multiple sclerosis Children: Item: Title: Abstract Item: Title: Background Item: Title: Materials and methods Children: Item: Title: Mice Item: Title: Sex as a biological variable Item: Title: EAE induction, OVA immunization and follow-up Item: Title: Peptides and liposomes Item: Title: Treatment of EAE mice with PS liposomes Item: Title: Treatment of EAE mice with fingolimod Item: Title: Motor function assessment Item: Title: Samples Item: Title: Splenocyte proliferation assay Item: Title: Cytokine production profile assay Item: Title: Flow cytometry Item: Title: Blocking antibodies Item: Title: ELISA anti-ovalbumin IgG Item: Title: Statistical analysis Item: Title: Results Children: Item: Title: PS liposome preparation and efficacy assessment of MOG-loaded PS liposomes in EAE Item: Title: MOG-loaded PS liposomes induce an immunomodulatory profile of T and B cells Item: Title: MOG-loaded PS liposomes promote antigen-specific tolerance through B cell- and treg-dependent mechanisms Item: Title: MOG-loaded PS liposomes do not prevent the immune response to MOG peptide Item: Title: MOG-loaded PS liposomes ameliorate EAE clinical course when neurological signs are already established Item: Title: Candidate routes of administration for clinical translation Item: Title: MOG-liposome therapy is effective in male mice and shows comparable efficacy to fingolimod in EAE Item: Title: Discussion Item: Title: Conclusions Item: Title: References Info: Creator: Adobe InDesign 18.3 (Windows) Producer: Adobe PDF Library 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