1e401a3a7897abf4b7860dbbed401896 327741.pdf 1cd24c9b32a841b656acebb37a0ec518f34c7437 327741.pdf cf8d58a386c2d80c0cbd4b38016f2b64e74d6b3e41282ced623a6e93dedc3d2b 327741.pdf Title: Impact of preanalytical delay on the performance of plasma Aβ42, Aβ42/40, p‐tau217, and p‐tau217/Aβ42 in detecting brain amyloidosis in the ALZAN cohort Subject: Keywords: Author: Creator: LaTeX with hyperref package Producer: Acrobat Distiller 10.0.0 (Windows) CreationDate: Thu Oct 30 10:02:01 2025 CET ModDate: Thu Oct 30 10:02:33 2025 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 8 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 494358 bytes Optimized: yes PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- NDAFMB+Lato-Regular Type 1C WinAnsi yes yes no 318 0 NDAGBP+Lato-Bold Type 1C WinAnsi yes yes no 321 0 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UseOutlines Outlines: Item: Title: Impact of preanalytical delay on the performance of plasma Ab42, Ab42/40, p-tau217, and p-tau217/Ab42 in detecting brain amyloidosis in the ALZAN cohort Destination: chapter..1 Children: Item: Title: Abstract Destination: section*.2 Item: Title: 1 | INTRODUCTION Destination: section..1.1 Item: Title: 2 | METHODS Destination: section..1.2 Children: Item: Title: 2.1 | Study cohorts Destination: subsection..1.2.1 Item: Title: 2.2 | Biological measurement in ALZAN Destination: subsection..1.2.2 Item: Title: 2.3 | Statistical analyses Destination: subsection..1.2.3 Item: Title: 3 | RESULTS Destination: section..1.3 Children: Item: Title: 3.1 | Participants and biomarker profile Destination: subsection..1.3.1 Item: Title: 3.2 | Impact of blood delay on biomarker values Destination: subsection..1.3.2 Children: Item: Title: 3.2.1 | Global performance of biomarkers in cohort and subcohorts stratified by preanalytical delay Destination: subsubsection..1.3.2.1 Item: Title: 3.2.2 | Impact of blood delay in a two-cut-offs “rule-in/rule-out” approach Destination: subsubsection..1.3.2.2 Item: Title: 4 | DISCUSSION Destination: section..1.4 Item: Title: AUTHOR CONTRIBUTIONS Destination: section*.4 Item: Title: ACKNOWLEDGMENT Destination: section*.6 Item: Title: CONFLICT OF INTEREST STATEMENT Destination: section*.8 Children: Item: Title: DATA AVAILABILITY STATEMENT Destination: section*.10 Item: Title: CONSENT STATEMENT Destination: section*.12 Item: Title: ORCID Destination: section*.14 Item: Title: REFERENCES Destination: section*.16 Item: Title: SUPPORTING INFORMATION Destination: section*.18 Info: Title: Impact of preanalytical delay on the performance of plasma Aβ42, Aβ42/40, p‐tau217, and p‐tau217/Aβ42 in detecting brain amyloidosis in the ALZAN cohort Author: Subject: Keywords: Creator: LaTeX with hyperref package Producer: Acrobat Distiller 10.0.0 (Windows) CreationDate: Thu Oct 30 10:32:01 CET 2025 ModDate: Thu Oct 30 10:32:33 CET 2025 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