a8259615e15d44fee7aa01a51e28089a 327839.pdf bf2cd6ed844394516098c8acc2ddc32090203cb4 327839.pdf c171ffbc5eb134c0c6f949b0bce2e9e9162d7af47480c8faf20e594d181b7972 327839.pdf Title: Prognostic value of whole lymph node molecular analysis in colorectal cancer: a prospective multicenter study Subject: Clinical and Experimental Medicine, https://doi.org/10.1007/s10238-025-01936-0 Keywords: Colorectal cancer; OSNA; Lymph node metastasis; Prognosis Author: Qing Liu Creator: Springer Producer: Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.5.13.4 ©2000-2024 iText Group NV (SPRINGER SBM; licensed version) CreationDate: Sat Oct 18 05:42:27 2025 CEST ModDate: Tue Nov 25 02:37:56 2025 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 1018136 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MyriadPro-SemiCn Type 1C WinAnsi yes no yes 49 0 MyriadPro-Semibold Type 1C Custom yes no yes 333 0 MyriadPro-SemiboldSemiCn Type 1C Custom yes no yes 97 0 MyriadPro-Bold Type 1C Custom yes no yes 50 0 UGMZTE+STIX-Regular Type 1C Custom yes yes yes 51 0 STIX-Italic Type 1C Custom yes no yes 83 0 YNLWDB+Wingdings-Regular Type 1C WinAnsi yes yes yes 334 0 MyriadPro-BoldSemiCn Type 1C Custom yes no yes 52 0 FFWCHI+Code2000 CID TrueType Identity-H yes yes yes 82 0 WSUKRV+MyriadPro-BoldSemiCnIt Type 1C WinAnsi yes yes yes 96 0 VJTBUQ+STIX-Bold Type 1C WinAnsi yes yes yes 98 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-04-22 04:05:13 CEST RepresentationInformation: 327839.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-04-21 12:03:28 CEST Size: 1018136 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 414 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Prognostic value of whole lymph node molecular analysis in colorectal cancer: a prospective multicenter study Children: Item: Title: Abstract Item: Title: Introduction Item: Title: Materials and methods Children: Item: Title: Study design and participants Item: Title: Lymph node processing and analysis Item: Title: One-step nucleic acid amplification (OSNA) assay Item: Title: CK 19 immunocytochemistry Item: Title: Estimation of sample size Item: Title: Statistical analysis Item: Title: Results Children: Item: Title: Patient characteristics Item: Title: LN analysis with OSNA versus. CS Item: Title: An optimal TTL cut-off Item: Title: Correlation of TTL with histological factors Item: Title: Prognostic relevance of TTL Item: Title: Discussion Item: Title: Conclusion Item: Title: Acknowledgements Item: Title: References Info: Title: Prognostic value of whole lymph node molecular analysis in colorectal cancer: a prospective multicenter study Author: Qing Liu Subject: Clinical and Experimental Medicine, https://doi.org/10.1007/s10238-025-01936-0 Keywords: Colorectal cancer; OSNA; Lymph node metastasis; Prognosis Creator: Springer Producer: Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.5.13.4 ©2000-2024 iText Group NV (SPRINGER SBM; licensed version) CreationDate: Sat Oct 18 06:12:27 CEST 2025 ModDate: Tue Nov 25 02:37:56 CET 2025 ID: 0x7a928fe175382f4d9ccb12e03039abc8, 0x136b3685d962eeabf81d584695db57be Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG 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