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Title:           Cortical microstructure is associated with disease severity and clinical progression in genetic frontotemporal dementia: a GENFI study
Subject:         Molecular Psychiatry, doi:10.1038/s41380-025-03280-x
Keywords:        
Author:          Elena Rodriguez-Vieitez
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      Title: Cortical microstructure is associated with disease severity and clinical progression in genetic frontotemporal dementia: a GENFI study
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       Item: 
        Title: Introduction
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       Item: 
        Title: Materials and methods
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        Children: 
         Item: 
          Title: Study participants and clinical assessment
          Destination: B1
         Item: 
          Title: Study subsample for disease staging
          Destination: B2
         Item: 
          Title: Study subsamples with longitudinal clinical follow-up data
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         Item: 
          Title: Acquisition of T1-weighted and diffusion-weighted MRI scans
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         Item: 
          Title: Cortical thickness processing
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         Item: 
          Title: Cortical mean diffusivity processing
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         Item: 
          Title: Statistical analysis
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         Item: 
          Title: Aim 1
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         Item: 
          Title: Aim 2
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         Item: 
          Title: Aim 3
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         Item: 
          Title: Aim 4
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       Item: 
        Title: Results
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        Children: 
         Item: 
          Title: Participants characteristics
          Destination: B12
         Item: 
          Title: Association of cortical microstructure and macrostructure with age in carriers vs non-carriers (Aim 1)
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         Item: 
          Title: Cortical microstructure and macrostructure in presymptomatic and symptomatic carriers (Aim 2)
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         Item: 
          Title: Cortical microstructure and macrostructure across stages of disease severity (Aim 3)
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         Item: 
          Title: Association of baseline cortical microstructure and macrostructure with longitudinal clinical progression (Aim 4)
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       Item: 
        Title: Discussion
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       Item: 
        Title: References
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       Item: 
        Title: Acknowledgements
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       Item: 
        Title: Author contributions
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       Item: 
        Title: Funding
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       Item: 
        Title: Competing interests
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       Item: 
        Title: Ethical approval and consent to participate
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       Item: 
        Title: ACKNOWLEDGMENTS
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        Title: ADDITIONAL INFORMATION
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    Title: Cortical microstructure is associated with disease severity and clinical progression in genetic frontotemporal dementia: a GENFI study
    Author: Elena Rodriguez-Vieitez
    Subject: Molecular Psychiatry, doi:10.1038/s41380-025-03280-x
    Keywords: 
    Creator: Springer
    CreationDate: Thu Nov 06 11:00:01 CET 2025
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                  <author:name>Matthis Synofzik</author:name>
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                           <pdfaProperty:description>ID of PDF/X standard</pdfaProperty:description>
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                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Mirrors crossmark:CrosMarkDomains</pdfaProperty:description>
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                           <pdfaProperty:description>Mirrors crossmark:DOI</pdfaProperty:description>
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                           <pdfaProperty:valueType>Seq Text</pdfaProperty:valueType>
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                           <pdfaProperty:description>CrossmarkDomainExclusive</pdfaProperty:description>
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                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Usual same as prism:doi</pdfaProperty:description>
                           <pdfaProperty:name>DOI</pdfaProperty:name>
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                           <pdfaProperty:description>The date when a publication was published.</pdfaProperty:description>
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                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
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                           <pdfaProperty:description>The aggregation type specifies the unit of aggregation for a content collection. &#xA;Comment &#xA;PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. &#xA;Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. &#xA;&#xA;</pdfaProperty:description>
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                           <pdfaProperty:description>Copyright </pdfaProperty:description>
                           <pdfaProperty:name>copyright</pdfaProperty:name>
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                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The Digital Object Identifier for the article.&#xA;The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. &#xA;If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). &#xA;</pdfaProperty:description>
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                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>ISSN for an electronic version of the issue in which the resource occurs. &#xA;Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. See prism:issn. &#xA;</pdfaProperty:description>
                           <pdfaProperty:name>issn</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
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                        <rdf:li rdf:parseType="Resource">
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                           <pdfaProperty:description>Title of the magazine, or other publication, in which a resource was/will be published. &#xA;Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. &#xA;&#xA;Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” &#xA;</pdfaProperty:description>
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                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>This element provides the url for an article or unit of content. &#xA;The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. &#xA;NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. &#xA;</pdfaProperty:description>
                           <pdfaProperty:name>url</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
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                  <pdfaSchema:prefix>sn</pdfaSchema:prefix>
                  <pdfaSchema:schema>Springer Nature ORCID Schema</pdfaSchema:schema>
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                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors.</pdfaProperty:description>
                           <pdfaProperty:name>authorInfo</pdfaProperty:name>
                           <pdfaProperty:valueType>Bag AuthorInformation</pdfaProperty:valueType>
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                  </pdfaSchema:property>
                  <pdfaSchema:valueType>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaType:description>Specifies the types of author information: name and ORCID of an author.</pdfaType:description>
                           <pdfaType:namespaceURI>http://springernature.com/ns/xmpExtensions/2.0/authorInfo/</pdfaType:namespaceURI>
                           <pdfaType:prefix>author</pdfaType:prefix>
                           <pdfaType:type>AuthorInformation</pdfaType:type>
                           <pdfaType:field>
                              <rdf:Seq>
                                 <rdf:li rdf:parseType="Resource">
                                    <pdfaField:description>Gives the ORCID of an author.</pdfaField:description>
                                    <pdfaField:name>orcid</pdfaField:name>
                                    <pdfaField:valueType>URI</pdfaField:valueType>
                                 </rdf:li>
                                 <rdf:li rdf:parseType="Resource">
                                    <pdfaField:description>Gives the name of an author.</pdfaField:description>
                                    <pdfaField:name>name</pdfaField:name>
                                    <pdfaField:valueType>Text</pdfaField:valueType>
                                 </rdf:li>
                              </rdf:Seq>
                           </pdfaType:field>
                        </rdf:li>
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                  </pdfaSchema:valueType>
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               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.niso.org/schemas/jav/1.0/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>jav</pdfaSchema:prefix>
                  <pdfaSchema:schema>NISO</pdfaSchema:schema>
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  Checksum: e0c95bf5
   Type: CRC32
  Checksum: c5bc64450127065fa764f39400bcd7b2
   Type: MD5
  Checksum: fa80edee26117b2ef6eaa0b807f39cc77bbd12f1
   Type: SHA-1
  Checksum: 673b3656afa35da37f42734e43e1634b24e58f4442a4dcacfbf638c41763c8c4
   Type: SHA-256