0b5a5956fd90aeed036c485e80cb4f5a 1-s2.0-S0720048X25002621-main.pdf 0e721f1d0eff659b24178f120b6c14f4a983a975 1-s2.0-S0720048X25002621-main.pdf edcd7e2ab35402897a59ea21d8154cce395159a1a3450a5331fceaebe9f9d26f 1-s2.0-S0720048X25002621-main.pdf Title: Local anaesthesia and pain management in image-guided breast interventions: Empathy in action Subject: European Journal of Radiology, 189 (2025) 112176. doi:10.1016/j.ejrad.2025.112176 Keywords: Breast Imaging,Image-guided procedures,Local anaesthesia,Pain pathways,Patient experience Author: Rodrigo Alcantara Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Sat Jun 7 17:39:29 2025 CEST ModDate: Sat Jun 7 18:01:09 2025 CEST Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 3913856 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID 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03:08:49 CEST RepresentationInformation: 1-s2.0-S0720048X25002621-main.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-04-21 20:09:49 CEST Size: 3913856 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Tagged PDF PDFMetadata: Objects: 2029 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: true NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: English Outlines: Item: Title: Local anaesthesia and pain management in image-guided breast interventions: Empathy in action Destination: mk:title Children: Item: Title: 1 Introduction Destination: mk:H1_1 Item: Title: 2 Background: Pain mechanisms in breast interventions Destination: mk:H1_2 Children: Item: Title: 2.1 Nerve supply Destination: mk:H2_1 Item: Title: 2.2 Nociceptors and pain perception Destination: mk:H2_2 Item: Title: 2.3 Skin and subcutaneous anatomy considerations Destination: mk:H2_3 Item: Title: 3 Local anaesthetics Destination: mk:H1_3 Children: Item: Title: 3.1 Overview of local anaesthetics Destination: mk:H2_4 Item: Title: 3.2 Common agents and properties Destination: mk:H2_5 Item: Title: 3.3 Newer Formulations of Local Anaesthetics Destination: mk:H2_6 Item: Title: 3.4 Vasoconstrictors Destination: mk:H2_7 Item: Title: 3.5 Combining LA Destination: mk:H2_8 Item: Title: 4 Safety considerations Destination: mk:H1_4 Children: Item: Title: 4.1 Breast procedures during pregnancy and lactation Destination: mk:H2_9 Item: Title: 4.2 Allergic reactions Destination: mk:H2_10 Item: Title: 4.3 Local anaesthetic systemic toxicity (LAST) Destination: mk:H2_11 Item: Title: 5 Supplementary approaches for LA Destination: mk:H1_5 Children: Item: Title: 5.1 Buffering (neutralising) with sodium bicarbonate Destination: mk:H2_12 Item: Title: 5.2 Warming of solutions Destination: mk:H2_13 Item: Title: 5.3 Hyaluronidase Destination: mk:H2_14 Item: Title: 5.4 Topical anaesthetics and vapocoolants Destination: mk:H2_15 Item: Title: 6 Practical insights for breast interventions Destination: mk:H1_6 Children: Item: Title: 6.1 Optimising injection techniques Destination: mk:H2_16 Item: Title: 6.2 Minimal sedation Destination: mk:H2_17 Item: Title: 6.3 Practical adaptations for specific interventions Destination: mk:H2_18 Item: Title: 7 Patient-centred care Destination: mk:H1_7 Children: Item: Title: 7.1 Empathy and communication Destination: mk:H2_19 Item: Title: 7.2 Pre-procedural communication and preparation Destination: mk:H2_20 Item: Title: 7.3 Psychological and behavioural interventions Destination: mk:H2_21 Item: Title: 7.4 Continuous improvement and patient-reported outcomes (PRO) Destination: mk:H2_22 Item: Title: 8 Conclusion Destination: mk:H1_8 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http://creativecommons.org/licenses/by/4.0/ elsevier.com sciencedirect.com true 10.1016/j.ejrad.2025.112176 2010-04-23 application/pdf 10.1016/j.ejrad.2025.112176 Elsevier B.V. European Journal of Radiology, 189 (2025) 112176. doi:10.1016/j.ejrad.2025.112176 Breast Imaging Image-guided procedures Local anaesthesia Pain pathways Patient experience Local anaesthesia and pain management in image-guided breast interventions: Empathy in action Rodrigo Alcantara E.Natalia Arenas Javier Azcona Mireia Pitarch Elisenda Vall Elisabet Vila-Trias Belen Ejarque José Maria Maiques Antonio Montes VoR 7th June 2025 Acrobat Distiller 8.1.0 (Windows) Breast Imaging,Image-guided procedures,Local anaesthesia,Pain pathways,Patient experience 7th June 2025 sciencedirect.com elsevier.com true 2010-04-23 10.1016/j.ejrad.2025.112176 noindex journal © 2025 The Authors. Published by Elsevier B.V. 2025-08-01 1 August 2025 10.1016/j.ejrad.2025.112176 0720-048X 112176 European Journal of Radiology 112176 https://doi.org/10.1016/j.ejrad.2025.112176 189 https://www.elsevier.com/tdm/tdmrep-policy.json 1 2025-06-07T15:39:29 Elsevier 2025-06-07T16:01:09 2025-06-07T16:01:09 uuid:1b499bed-4ce8-4c0c-b682-0d58baae1cbe uuid:b6ed5266-03cb-4855-90c0-636283357f42 True Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 125, 576, 129, 586 Flags: Print Destination: 1886 Annotation: Subtype: Link Rect: 131, 576, 136, 586 Flags: Print Destination: 1886 Annotation: Subtype: Link Rect: 138, 576, 142, 586 Flags: Print Destination: 1886 Annotation: Subtype: Link Rect: 144, 576, 148, 586 Flags: Print Destination: 1886 Annotation: Subtype: Link Rect: 235, 576, 239, 586 Flags: Print Destination: 1886 Annotation: Subtype: Link Rect: 314, 576, 318, 586 Flags: Print Destination: 1886 Annotation: Subtype: Link Rect: 321, 576, 325, 586 Flags: Print Destination: 1886 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