a6731524f8f7a759d135e62e2dd254df jouinf_a2025m9v91n3p106567.pdf f39d72827fd9e723852d552e4adb2902d3b80574 jouinf_a2025m9v91n3p106567.pdf 5c684ded3b0487e258145c5c4c3d373baeff58477860c180477e8fdcd6e19702 jouinf_a2025m9v91n3p106567.pdf Title: Evolutionary dynamics of HRSV following the implementation of nirsevimab immunoprophylaxis in Catalonia (2023-2024) Subject: Journal of Infection, 91 (2025) 106567. doi:10.1016/j.jinf.2025.106567 Keywords: Human Respiratory Syncytial Virus; Public Health Surveillance; Monoclonal Antibody; Whole Genome Sequencing; Population Genetics; Molecular Evolution; Genetic Drift; Genetic Fitness; Author: Alejandra González-Sánchez Creator: Elsevier CreationDate: Thu Sep 11 08:21:18 2025 CEST ModDate: Thu Sep 11 08:22:00 2025 CEST Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 5079033 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- DKUJMJ+UniversLTStd Type 1C Custom yes yes yes 1424 0 DDRZNZ+Gulliver Type 1C Custom yes yes yes 1425 0 KHXVVI+STIXGeneral-Regular Type 1C Custom yes yes yes 1430 0 JLPQRU+Gulliver-Italic Type 1C Custom yes yes yes 1431 0 FCCSXD+ArialUnicodeMS CID TrueType Identity-H yes yes yes 1440 0 OROEFB+GulliverSCOsF Type 1C Custom yes yes yes 1442 0 XERUPH+TimesNewRoman CID TrueType Identity-H yes yes yes 1445 0 AUPQTK+Gulliver-Bold Type 1C Custom yes yes yes 39 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-05-07 04:02:53 CEST RepresentationInformation: jouinf_a2025m9v91n3p106567.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-05-06 19:49:17 CEST Size: 5079033 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF, Tagged PDF PDFMetadata: Objects: 1510 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Evolutionary dynamics of HRSV following the implementation of nirsevimab immunoprophylaxis in Catalonia (2023-2024) Destination: mk:titletit0005 Children: Item: Title: Introduction Destination: mk:H1_1 Item: Title: Materials and methods Destination: mk:H1_2 Children: Item: Title: Sample collection Destination: mk:H2_3 Item: Title: Genetic characterisation based on whole-genome sequencing Destination: mk:H2_4 Item: Title: Phylogenetic analyses and lineage assignment Destination: mk:H2_5 Item: Title: Nucleotide diversity Destination: mk:H2_6 Item: Title: Mutation analysis of the F protein Destination: mk:H2_7 Item: Title: Selection pressure analysis Destination: mk:H2_8 Item: Title: Results Destination: mk:H1_9 Children: Item: Title: Sample collection Destination: mk:H2_10 Item: Title: Genetic characterisation based on whole-genome sequencing Destination: mk:H2_11 Item: Title: Phylogenetic analyses and lineage assignment Destination: mk:H2_12 Item: Title: Nucleotide diversity Destination: mk:H2_13 Item: Title: Mutation analysis of the F protein Destination: mk:H2_14 Item: Title: Selection pressure analysis Destination: mk:H2_15 Item: Title: Discussion Destination: mk:H1_16 Item: Title: Funding Destination: mk:H1_17 Item: Title: Declaration of Competing Interest Destination: mk:H1_18 Item: Title: Declaration of Generative AI and AI-assisted technologies in the writing process Destination: mk:H1_19 Item: Title: Acknowledgements Destination: mk:H1_20 Item: Title: Appendix A. Supporting information Destination: mk:H1_21 Item: Title: References Destination: mk:H1_22 Info: Title: Evolutionary dynamics of HRSV following the implementation of nirsevimab immunoprophylaxis in Catalonia (2023-2024) Author: Alejandra González-Sánchez Subject: Journal of Infection, 91 (2025) 106567. doi:10.1016/j.jinf.2025.106567 Keywords: Human Respiratory Syncytial Virus; Public Health Surveillance; Monoclonal Antibody; Whole Genome Sequencing; Population Genetics; Molecular Evolution; Genetic Drift; Genetic Fitness; Creator: Elsevier CreationDate: Thu Sep 11 08:51:18 CEST 2025 ModDate: Thu Sep 11 08:52:00 CEST 2025 ID: 0x023beb23b345be456540d6e0e0d0728a, 0xf6bc098cc48da047892dd6329d50c6a6 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 247 ImageHeight: 272 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG 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XERUPH+TimesNewRoman CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: XERUPH+TimesNewRoman Flags: Nonsymbolic FontBBox: -77, -225, 1009, 878 FontFile2: true Font: BaseFont: FCCSXD+ArialUnicodeMS CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: FCCSXD+ArialUnicodeMS Flags: Nonsymbolic FontBBox: -1011, -330, 2260, 1078 FontFile2: true XMP: application/pdf doi:10.1016/j.jinf.2025.106567 Elsevier Journal of Infection, 91 (2025) 106567. doi:10.1016/j.jinf.2025.106567 Human Respiratory Syncytial Virus Public Health Surveillance Monoclonal Antibody Whole Genome Sequencing Population Genetics Molecular Evolution Genetic Drift Genetic Fitness Evolutionary dynamics of HRSV following the implementation of nirsevimab immunoprophylaxis in Catalonia (2023-2024) Alejandra González-Sánchez Cristina Andrés Ignasi Prats-Méndez Maria Piñana Ermengol Coma Albert Bernet Cristina Casañ Miguel Torralba-Calero Cristina Gutiérrez Gemma Recio Comí Laura Calatayud Narcís Saubi Anna Creus-Costa Jorgina Vila Maria Arnedo-Muñoz Ariadna Rando Patricia Nadal-Baron Juliana Esperalba Eva Balada Antoni Soriano-Arandes Josefina Ayats Jacobo Mendioroz Juan José González-López Nieves Larrosa Tomàs Pumarola Jaime Martínez-Urtaza Andrés Antón journal Journal of Infection © 2025 Published by Elsevier Ltd on behalf of The British Infection Association. 0163-4453 91 3 106567 106567 10.1016/j.jinf.2025.106567 https://doi.org/10.1016/j.jinf.2025.106567 2010-04-23 true 10.1016/j.jinf.2025.106567 elsevier.com sciencedirect.com 7.0 10.1016/j.jinf.2025.106567 noindex 2010-04-23 true elsevier.com sciencedirect.com VoR Elsevier 2025-09-11T11:52+05:30 2025-09-11T11:51:18+05:30 2025-09-11T11:52+05:30 True Human Respiratory Syncytial Virus; Public Health Surveillance; Monoclonal Antibody; Whole Genome Sequencing; Population Genetics; Molecular Evolution; Genetic Drift; Genetic Fitness; 1 https://www.elsevier.com/tdm/tdmrep-policy.json 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