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Title:           Severe Hypertriglyceridemia in Pregnancy: Clinical Approach and Management Strategies
Subject:         DOI: 10.1210/jcemcr/luaf253; JCEM Case Reports, 3, 12, 2025-11-05.; Abstract: Severe hypertriglyceridemia (HTG) during pregnancy is a rare but serious condition associated with an increased risk of maternal and fetal complications. We report the case of a 36-year-old woman diagnosed with severe HTG at 28 weeks of gestation, with triglyceride (TG) levels of 2184 mg/dL (SI: 24.68 mmol/L) (reference range, 26.50-150 mg/dL [SI: 0.30-1.69 mmol/L]). Despite dietary intervention and ω-3 supplementation, levels continued to rise, requiring hospitalization and treatment with intravenous insulin. Due to refractory HTG, plasmapheresis was initiated at 33 weeks, with significant lipid reduction. At 34 weeks, the patient underwent an emergency cesarean delivery due to preterm labor. This case underscores the challenges of managing severe HTG in pregnancy and highlights the importance of early, multidisciplinary intervention. Further research is needed to refine treatment strategies and establish 
Keywords:        hypertriglyceridemia; pregnancy; plasmapheresis; intravenous insulin; triglycerides; gestational complications
Author:          Aina Raventós
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  Checksum: c05ab190
   Type: CRC32
  Checksum: 086d91e4e94138fb3cbbcfe19562509a
   Type: MD5
  Checksum: bb26ad0266a3c74c3d86d49a9bbe25377610a065
   Type: SHA-1
  Checksum: 834ef887a7297e6f9b2650837514dcaafb9678293f934e1f6d4c438855d7704d
   Type: SHA-256