873a762ef8d0ee9185d832491779b7cf 00211-2024.pdf d9940820140d8e30a944c3afa4472cba2f6fbf61 00211-2024.pdf 9c1cfc380ac37aced545714dcd2bfbc55724349c64fef57e2f6cd6334cc4de2b 00211-2024.pdf Title: Time is lung: higher preservation of lung function in severe asthma patients after earlier mepolizumab treatment Keywords: Author: Francisco-Javier González-Barcala Creator: Arbortext Advanced Print Publisher 10.0.1465/W Unicode Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Tue Jan 28 11:16:24 2025 CET ModDate: Sat Feb 1 04:43:15 2025 CET Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 548793 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- AMDNDP+AdvTT3e3c8cd7 Type 1C WinAnsi yes yes no 193 0 AMDNNM+AdvTT7e2c4963 Type 1C WinAnsi yes yes no 194 0 AMDNNN+AdvTT7e2c4963+20 Type 1C WinAnsi yes yes no 200 0 AMDOBN+AdvTTcabc3928.I Type 1C WinAnsi yes yes no 205 0 AMDOBO+AdvTT28ecec5c.I Type 1C WinAnsi yes yes no 206 0 AMDOBP+AdvTT1778526c Type 1C WinAnsi yes yes no 207 0 AMDOCA+AdvTT1420aa1a.I Type 1C WinAnsi yes yes no 212 0 AMDOCB+AdvOT8608a8d1+2a Type 1C Custom yes yes yes 213 0 AMDODC+AdvTT13bd1210.B+20 Type 1C WinAnsi yes yes no 214 0 AMDOMP+AdvOT8608a8d1+22 Type 1C Custom yes yes no 92 0 AMDONP+AdvTT1778526c+20 Type 1C WinAnsi yes yes no 98 0 AMDPBP+SourceSansPro-Regular Type 1C Custom yes yes yes 105 0 AMEAFI+AdvOT8b40f9c2.B+22 Type 1C Custom yes yes no 107 0 AMEAGJ+AdvOT8b40f9c2.B+2a Type 1C Custom yes yes yes 108 0 AMEAHK+AdvTT3e3c8cd7+01 Type 1C Custom yes yes yes 112 0 AMEAHL+AdvTT1778526c+01 Type 1C Custom yes yes yes 114 0 AMEAIL+AdvTT7e2c4963+01 Type 1C Custom yes yes yes 113 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-05-20 04:05:31 CEST RepresentationInformation: 00211-2024.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-05-19 15:59:46 CEST Size: 548793 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 251 FreeObjects: 1 IncrementalUpdates: 2 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Time is lung: higher preservation of lung function in severe asthma patients after earlier mepolizumab treatment Destination: head1 Children: Item: Title: Abstract Destination: head2 Item: Title: Introduction Destination: head3 Item: Title: Methods Destination: head4 Item: Title: Results Destination: head5 Item: Title: Discussion Destination: head6 Children: Item: Title: Conclusion Destination: head7 Item: Title: References Destination: head8 Info: Title: Time is lung: higher preservation of lung function in severe asthma patients after earlier mepolizumab treatment Author: Francisco-Javier González-Barcala Keywords: Creator: Arbortext Advanced Print Publisher 10.0.1465/W Unicode Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Tue Jan 28 11:46:24 CET 2025 ModDate: Sat Feb 01 05:13:15 CET 2025 ID: 0x567a1ca6090dee58ce0a6516547b34c7, 0xce51d6baf665944481e0f09860357caa Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: AMDNDP+AdvTT3e3c8cd7 FontSubset: true FirstChar: 37 LastChar: 243 FontDescriptor: FontName: AMDNDP+AdvTT3e3c8cd7 Flags: Serif, Nonsymbolic FontBBox: -41, -250, 822, 885 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AMDNNM+AdvTT7e2c4963 FontSubset: true FirstChar: 35 LastChar: 248 FontDescriptor: FontName: AMDNNM+AdvTT7e2c4963 Flags: Serif, Nonsymbolic FontBBox: -31, -250, 791, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AMDONP+AdvTT1778526c+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: AMDONP+AdvTT1778526c+20 Flags: Nonsymbolic FontBBox: -208, -250, 1062, 822 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AMDNNN+AdvTT7e2c4963+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: AMDNNN+AdvTT7e2c4963+20 Flags: Nonsymbolic FontBBox: -447, -250, 1156, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AMDPBP+SourceSansPro-Regular FontSubset: true FirstChar: 2 LastChar: 150 FontDescriptor: FontName: AMDPBP+SourceSansPro-Regular Flags: Symbolic FontBBox: 0, -224, 790, 732 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AMEAFI+AdvOT8b40f9c2.B+22 FontSubset: true FirstChar: 21 LastChar: 21 FontDescriptor: FontName: AMEAFI+AdvOT8b40f9c2.B+22 Flags: Nonsymbolic FontBBox: 0, -406, 1343, 937 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: AMEAGJ+AdvOT8b40f9c2.B+2a FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: AMEAGJ+AdvOT8b40f9c2.B+2a Flags: Symbolic FontBBox: 19, -447, 1656, 958 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AMDOBN+AdvTTcabc3928.I FontSubset: true FirstChar: 40 LastChar: 121 FontDescriptor: FontName: AMDOBN+AdvTTcabc3928.I Flags: Serif, Nonsymbolic FontBBox: -114, -250, 822, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AMDOBO+AdvTT28ecec5c.I FontSubset: true FirstChar: 41 LastChar: 117 FontDescriptor: FontName: AMDOBO+AdvTT28ecec5c.I Flags: Serif, Nonsymbolic FontBBox: -125, -250, 833, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AMDOBP+AdvTT1778526c FontSubset: true FirstChar: 37 LastChar: 183 FontDescriptor: FontName: AMDOBP+AdvTT1778526c Flags: Serif, Nonsymbolic FontBBox: -20, -208, 937, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AMEAHK+AdvTT3e3c8cd7+01 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: AMEAHK+AdvTT3e3c8cd7+01 Flags: Symbolic FontBBox: -41, -250, 802, 979 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AMEAIL+AdvTT7e2c4963+01 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: AMEAIL+AdvTT7e2c4963+01 Flags: Symbolic FontBBox: -41, -250, 791, 958 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AMEAHL+AdvTT1778526c+01 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: AMEAHL+AdvTT1778526c+01 Flags: Symbolic FontBBox: -72, -208, 1270, 979 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AMDOCA+AdvTT1420aa1a.I FontSubset: true FirstChar: 46 LastChar: 118 FontDescriptor: FontName: AMDOCA+AdvTT1420aa1a.I Flags: Nonsymbolic FontBBox: -104, -208, 906, 854 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AMDOCB+AdvOT8608a8d1+2a FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: AMDOCB+AdvOT8608a8d1+2a Flags: Symbolic FontBBox: 0, -437, 1385, 937 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: AMDODC+AdvTT13bd1210.B+20 FontSubset: true FirstChar: 150 LastChar: 150 FontDescriptor: FontName: AMDODC+AdvTT13bd1210.B+20 Flags: Nonsymbolic FontBBox: -208, -260, 1187, 822 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: AMDOMP+AdvOT8608a8d1+22 FontSubset: true FirstChar: 21 LastChar: 21 FontDescriptor: FontName: AMDOMP+AdvOT8608a8d1+22 Flags: Nonsymbolic FontBBox: 0, -322, 1218, 968 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true XMP: Arbortext Advanced Print Publisher 10.0.1465/W Unicode 2025-02-01T09:13:15+05:30 2025-01-28T15:46:24+05:30 2025-02-01T09:13:15+05:30 application/pdf 10.1183/23120541.00211-2024 Time is lung: higher preservation of lung function in severe asthma patients after earlier mepolizumab treatment Francisco-Javier González-Barcala Javier Domínguez-Ortega David Bañas-Conejero Esteban Antelo-Cea Eva Martínez-Moragón Teresa Carrillo-Díaz Marina Blanco-Aparicio Christian Domingo Acrobat Distiller 8.1.0 (Windows) uuid:44169c96-61dd-418b-9251-a1aef46b9e9a uuid:be6ec035-9851-4f9e-99b2-d09289cad7f6 http://dx.doi.org/10.1183/23120541.00211-2024 10.1183/23120541.00211-2024 10.1183/23120541.00211-2024 false 2014-12-12 psychoceramics.labs.crossref.org false 2014-12-12 10.1183/23120541.00211-2024 psychoceramics.labs.crossref.org Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 206, 622, 215, 631 Annotation: Subtype: Link Rect: 470, 609, 479, 618 Annotation: Subtype: Link Rect: 276, 596, 284, 605 Annotation: Subtype: Link Rect: 465, 466, 550, 475 Annotation: Subtype: Link Rect: 42, 407, 78, 442 Annotation: Subtype: Link Rect: 310, 408, 334, 417 Annotation: Subtype: Link Rect: 310, 408, 392, 417 Annotation: Subtype: Link Rect: 282, 368, 419, 377 Annotation: Subtype: Link Rect: 167, 75, 171, 84 Destination: 85 Annotation: Subtype: Link Rect: 177, 75, 182, 84 Destination: 85 Annotation: Subtype: Link Rect: 487, 64, 492, 73 Destination: 85 Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 460, 713, 464, 722 Destination: 85 Annotation: Subtype: Link Rect: 297, 691, 302, 700 Destination: 85 Annotation: Subtype: Link Rect: 234, 647, 239, 656 Destination: 85 Annotation: Subtype: Link Rect: 315, 636, 319, 645 Destination: 85 Annotation: Subtype: Link Rect: 412, 614, 417, 623 Destination: 85 Annotation: Subtype: Link Rect: 214, 592, 218, 601 Destination: 85 Annotation: Subtype: Link Rect: 225, 592, 229, 601 Destination: 85 Annotation: Subtype: Link Rect: 518, 581, 527, 590 Destination: 85 Annotation: Subtype: Link Rect: 407, 537, 416, 546 Destination: 85 Annotation: Subtype: Link Rect: 421, 537, 430, 546 Destination: 85 Annotation: Subtype: Link Rect: 368, 482, 377, 491 Destination: 85 Annotation: Subtype: Link Rect: 382, 482, 391, 491 Destination: 85 Annotation: Subtype: Link Rect: 274, 438, 283, 447 Destination: 85 Annotation: Subtype: Link Rect: 209, 427, 218, 436 Destination: 85 Annotation: Subtype: Link Rect: 223, 427, 232, 436 Destination: 85 Annotation: Subtype: Link Rect: 538, 229, 547, 238 Destination: 85 Annotation: Subtype: Link Rect: 451, 75, 460, 84 Destination: 89 Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 273, 526, 305, 535 Destination: 21 Annotation: Subtype: Link Rect: 310, 526, 315, 535 Destination: 35 Annotation: Subtype: Link Rect: 333, 526, 337, 535 Destination: 35 Annotation: Subtype: Link Rect: 477, 441, 505, 450 Destination: 45 Annotation: Subtype: Link Rect: 523, 441, 527, 450 Destination: 45 Annotation: Subtype: Link Rect: 309, 397, 337, 406 Destination: 45 Annotation: Subtype: Link Rect: 355, 397, 359, 406 Destination: 45 Annotation: Subtype: Link Rect: 483, 353, 510, 362 Destination: 45 Annotation: Subtype: Link Rect: 528, 353, 533, 362 Destination: 45 Page: Label: 4 Annotations: Annotation: Subtype: Link Rect: 199, 392, 223, 401 Destination: 50 Annotation: Subtype: Link Rect: 164, 370, 198, 379 Destination: 63 Annotation: Subtype: Link Rect: 216, 370, 221, 379 Destination: 63 Page: Label: 5 Rotate: 90 Page: Label: 6 Rotate: 90 Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 265, 472, 290, 481 Destination: 50 Annotation: Subtype: Link Rect: 362, 450, 386, 459 Destination: 50 Annotation: Subtype: Link Rect: 512, 417, 536, 426 Destination: 50 Annotation: Subtype: Link Rect: 211, 285, 243, 294 Destination: 21 Annotation: Subtype: Link Rect: 261, 285, 266, 294 Destination: 35 Page: Label: 8 Annotations: Annotation: Subtype: Link Rect: 523, 691, 531, 700 Destination: 89 Annotation: Subtype: Link Rect: 194, 647, 203, 656 Destination: 85 Annotation: Subtype: Link Rect: 367, 625, 376, 634 Destination: 89 Annotation: Subtype: Link Rect: 515, 471, 524, 480 Destination: 89 Annotation: Subtype: Link Rect: 219, 383, 228, 392 Destination: 89 Annotation: Subtype: Link Rect: 541, 339, 550, 348 Destination: 89 Annotation: Subtype: Link Rect: 164, 328, 173, 337 Destination: 89 Page: Label: 9 Annotations: Annotation: Subtype: Link Rect: 301, 582, 382, 590 Page: Label: 10 Checksum: d791be0a Type: CRC32 Checksum: 873a762ef8d0ee9185d832491779b7cf Type: MD5 Checksum: d9940820140d8e30a944c3afa4472cba2f6fbf61 Type: SHA-1 Checksum: 9c1cfc380ac37aced545714dcd2bfbc55724349c64fef57e2f6cd6334cc4de2b Type: SHA-256