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Title:           Beta-hydroxybutyrate counteracts the deleterious effects of a saturated high-fat diet on synaptic AMPAR receptors and cognitive performance
Subject:         Molecular Metabolism, 99 (2025) 102207. doi:10.1016/j.molmet.2025.102207
Author:          Rocío Rojas
Creator:         Elsevier
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      Title: Beta-hydroxybutyrate counteracts the deleterious effects of a saturated high-fat diet on synaptic AMPAR receptors and cogni ...
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       Item: 
        Title: 1. Introduction
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        Title: 2. Materials and methods
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         Item: 
          Title: 2.1. Animals and study design
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         Item: 
          Title: 2.2. Primary neuronal cultures
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          Title: 2.3. Cellular treatments
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          Title: 2.4. Immunostaining, image acquisition, and analysis
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          Title: 2.5. AMPA-mediated miniature excitatory postsynaptic currents
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          Title: 2.6. Hippocampal slice preparation and electrophysiology
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          Title: 2.7. BHB determination
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          Title: 2.8. Behavior tests
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          Title: 2.9. Statistical analysis
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        Title: 3. Results
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         Item: 
          Title: 3.1. Effect of fatty acids and BHB on GluA1 surface levels and AMPAR-mediated synaptic transmission in cortical neurons
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          Title: 3.2. BHB mitigates palmitate-mediated decrease in synaptic GluA1 levels and restores synaptic transmission in hippocampal neurons
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          Title: 3.3. BHB restores palmitate-induced impairment in hippocampal synaptic plasticity
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          Title: 3.4. BHB counteracts the cognitive impairment mediated by a saturated fatty acid-rich diet in mice
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        Title: 4. Discussion
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         Item: 
          Title: 4.1. BHB restores GluA1 synaptic levels and plasticity decreased by palmitate
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         Item: 
          Title: 4.2. BHB supplementation counteracts the cognitive impairment triggered by SFAD
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    Title: Beta-hydroxybutyrate counteracts the deleterious effects of a saturated high-fat diet on synaptic AMPAR receptors and cognitive performance
    Author: Rocío Rojas
    Subject: Molecular Metabolism, 99 (2025) 102207. doi:10.1016/j.molmet.2025.102207
    Creator: Elsevier
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  Checksum: c4638af4
   Type: CRC32
  Checksum: 2ddeb59cada122e2eb73ad297ad24353
   Type: MD5
  Checksum: 4ff70a96e8fcd2eb473f2f8dfd6d6548483df5c4
   Type: SHA-1
  Checksum: 18c08835c3deda8a2708a85a3d5df924f9d781b7a84f82da57d43f7c632bc31b
   Type: SHA-256