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Title:           Preexisting Diabetes and Pregnancy: An Endocrine Society and European Society of Endocrinology Joint Clinical Practice Guideline
Subject:         DOI: 10.1093/ejendo/lvaf116; European Journal of Endocrinology, 193, 1, 2025-07-13.; Abstract:  Background: Preexisting diabetes (PDM) increases the risk of maternal and perinatal mortality and morbidity. Reduction of maternal hyperglycemia prior to and during pregnancy can reduce these risks. Despite compelling evidence that preconception care (PCC), which includes achieving strict glycemic goals, reduces the risk of congenital malformations and other adverse pregnancy outcomes, only a minority of individuals receive PCC. Suboptimal pregnancy outcomes demonstrated in real-world data highlight the need to further optimize prenatal glycemia. New evolving technology shows promise in helping to achieve that goal. Dysglycemia is not the only driver of poor pregnancy outcomes in PDM. The increasing impact of obesity on pregnancy outcomes underscores the importance of optimal nutrition and management of insulin sensitizing medications during prenatal care for PDM. Objective: To provide rec
Keywords:        type 1 diabetes; type 2 diabetes; pregnancy; continuous glucose monitor (CGM); insulin pump; delivery timing; metformin; hybrid closed loop; automated insulin delivery; glucagon-like peptide -1 receptor agonist (GLP1-RA)
Author:          Jennifer A. Wyckoff
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      Title: Preexisting Diabetes and Pregnancy: An Endocrine Society and European Society of Endocrinology Joint Clinical Practice Guideline
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        Title: List of Recommendations
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        Title: Methods of Development of Evidence-Based Clinical Practice Guidelines
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       Item: 
        Title: Screening for Pregnancy Intention
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          Title: Background
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          Title: Summary of Evidence
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          Title: Benefits and Harms
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         Item: 
          Title: Other Evidence to Decision Criteria and Considerations
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         Item: 
          Title: Justification for the Recommendation
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         Item: 
          Title: Comments
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          Title: Research Considerations
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       Item: 
        Title: Contraception
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          Title: Background
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         Item: 
          Title: Summary of Evidence
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          Title: Benefits and Harms
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          Title: Other Evidence to Decision Criteria and Considerations
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          Title: Justification for the Recommendation
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          Title: Comments
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          Title: Research Considerations
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       Item: 
        Title: Glucagon-Like Peptide-1 Receptor Agonists
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          Title: Background
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          Title: Summary of Evidence
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          Title: Benefits and Harms
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          Title: Other Evidence to Decision Criteria and Considerations
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          Title: Justification for the Recommendation
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          Title: Comments
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          Title: Research Considerations
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       Item: 
        Title: Addition of Metformin for Patients on Insulin
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          Title: Background
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          Title: Summary of Evidence
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          Title: Benefits and Harms
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          Title: Other Evidence to Decision Criteria and Considerations
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          Title: Justification for the Recommendation
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          Title: Comments
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          Title: Research Considerations
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       Item: 
        Title: Carbohydrate-Restricted Diet
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         Item: 
          Title: Background
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          Title: Summary of Evidence
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          Title: Benefits and Harms
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          Title: Other Evidence to Decision Criteria and Considerations
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          Title: Justification for the Recommendation
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          Title: Comments
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          Title: Research Considerations
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       Item: 
        Title: Continuous Glucose Monitoring vs Self-Monitoring of Blood Glucose in Individuals With Preexisting Type 2 Diabetes Mellitus
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         Item: 
          Title: Background
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          Title: Summary of Evidence
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          Title: Benefits and Harms
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          Title: Other Evidence to Decision Factors
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          Title: Justification for the Recommendation
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          Title: Comments
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          Title: Research Considerations
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        Title: Single Continuous Glucose Monitor Glycemic Target vs Standard-of-Care Pregnancy Fasting and Postprandial Targets
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          Title: Background
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          Title: Summary of Evidence
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          Title: Benefits and Harms
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          Title: Use of an Alternative Single Glucose Target
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          Title: Other Evidence to Decision Criteria and Considerations
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          Title: Justification for the Recommendation
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          Title: Research Considerations
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        Title: Hybrid Closed-Loop Pump (Pump Adjusting Automatically Based on Continuous Glucose Monitor) vs Insulin Pump With Continuous Glucose Monitor (Without an Algorithm) or Multiple Daily Insulin Injections With Continuous Glucose Monitor
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          Title: Background
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          Title: Summary of Evidence
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          Title: Benefits and Harms
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          Title: Glucometrics
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          Title: Harms
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          Title: Other Evidence to Decision Criteria and Considerations
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          Title: Research Considerations
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        Title: Early Delivery Based on Risk Assessment
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          Title: Background
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          Title: Summary of Evidence
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          Title: Research Considerations
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        Title: Postpartum Endocrine Care
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          Title: Background
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          Title: Summary of Evidence
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          Title: Benefits and Harms
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          Title: Implementation Considerations
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          Title: Research Considerations
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        Title: Summary
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        Title: Acknowledgments
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        Title: Funding
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        Title: Disclaimer
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          Title: Summary
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          Title: Individual Disclosures, Conflicts, and Management Strategies
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   Info: 
    Title: Preexisting Diabetes and Pregnancy: An Endocrine Society and European Society of Endocrinology Joint Clinical Practice Guideline
    Author: Jennifer A. Wyckoff
    Subject: DOI: 10.1093/ejendo/lvaf116; European Journal of Endocrinology, 193, 1, 2025-07-13.; Abstract:  Background: Preexisting diabetes (PDM) increases the risk of maternal and perinatal mortality and morbidity. Reduction of maternal hyperglycemia prior to and during pregnancy can reduce these risks. Despite compelling evidence that preconception care (PCC), which includes achieving strict glycemic goals, reduces the risk of congenital malformations and other adverse pregnancy outcomes, only a minority of individuals receive PCC. Suboptimal pregnancy outcomes demonstrated in real-world data highlight the need to further optimize prenatal glycemia. New evolving technology shows promise in helping to achieve that goal. Dysglycemia is not the only driver of poor pregnancy outcomes in PDM. The increasing impact of obesity on pregnancy outcomes underscores the importance of optimal nutrition and management of insulin sensitizing medications during prenatal care for PDM. Objective: To provide rec
    Keywords: type 1 diabetes; type 2 diabetes; pregnancy; continuous glucose monitor (CGM); insulin pump; delivery timing; metformin; hybrid closed loop; automated insulin delivery; glucagon-like peptide -1 receptor agonist (GLP1-RA)
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         <pdf:Keywords>type 1 diabetes; type 2 diabetes; pregnancy; continuous glucose monitor (CGM); insulin pump; delivery timing; metformin; hybrid closed loop; automated insulin delivery; glucagon-like peptide -1 receptor agonist (GLP1-RA)</pdf:Keywords>
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               <rdf:li xml:lang="x-default">Preexisting Diabetes and Pregnancy: An Endocrine Society and European Society of Endocrinology Joint Clinical Practice Guideline</rdf:li>
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               <rdf:li>Jennifer A. Wyckoff</rdf:li>
               <rdf:li>Annunziata Lapolla</rdf:li>
               <rdf:li>Bernadette D. Asias-Dinh</rdf:li>
               <rdf:li>Linda A. Barbour</rdf:li>
               <rdf:li>Florence M. Brown</rdf:li>
               <rdf:li>Patrick M. Catalano</rdf:li>
               <rdf:li>Rosa Corcoy</rdf:li>
               <rdf:li>Gian Carlo Di Renzo</rdf:li>
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               <rdf:li>Melanie Stephenson-Gray</rdf:li>
               <rdf:li>Adam G. Tabák</rdf:li>
               <rdf:li>Emily Weatherup</rdf:li>
               <rdf:li>Chloe Zera</rdf:li>
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               <rdf:li xml:lang="x-default">DOI: 10.1093/ejendo/lvaf116; European Journal of Endocrinology, 193, 1, 2025-07-13.; Abstract:  Background: Preexisting diabetes (PDM) increases the risk of maternal and perinatal mortality and morbidity. Reduction of maternal hyperglycemia prior to and during pregnancy can reduce these risks. Despite compelling evidence that preconception care (PCC), which includes achieving strict glycemic goals, reduces the risk of congenital malformations and other adverse pregnancy outcomes, only a minority of individuals receive PCC. Suboptimal pregnancy outcomes demonstrated in real-world data highlight the need to further optimize prenatal glycemia. New evolving technology shows promise in helping to achieve that goal. Dysglycemia is not the only driver of poor pregnancy outcomes in PDM. The increasing impact of obesity on pregnancy outcomes underscores the importance of optimal nutrition and management of insulin sensitizing medications during prenatal care for PDM. Objective: To provide rec</rdf:li>
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               <rdf:li xml:lang="x-default">This article has been co-published with permission in European Journal of Endocrinology and The Journal of Clinical Endocrinology &amp; Metabolism © The Author(s) 2025. Published by Oxford University Press on behalf of the European Society of Endocrinology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com. The articles are identical except for minor stylistic and spelling differences in keeping with each journal's style.</rdf:li>
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               <rdf:li>pregnancy</rdf:li>
               <rdf:li>continuous glucose monitor (CGM)</rdf:li>
               <rdf:li>insulin pump</rdf:li>
               <rdf:li>delivery timing</rdf:li>
               <rdf:li>metformin</rdf:li>
               <rdf:li>hybrid closed loop</rdf:li>
               <rdf:li>automated insulin delivery</rdf:li>
               <rdf:li>glucagon-like peptide -1 receptor agonist (GLP1-RA)</rdf:li>
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         <prism:doi>10.1093/ejendo/lvaf116</prism:doi>
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