ae10dc58209a2f2065cdfb3604003b37 328738.pdf b86ebd64fb5008db6a1e3e0f08e994521ac93d7c 328738.pdf 4c69e4920855077948d662a5fb7a20a5f86760b76f6d67b721e20d74fd868789 328738.pdf Title: drm_547142_Lebrikizumab Improved Itch Symptoms and Reduced Itch Interference on Sleep over 52 Weeks in Patients with Moderate-to-Severe Atopic Dermatitis in Two Phase 3 Trials Creator: PTC Arbortext Layout Developer 12.3.6865/W-x64 Producer: PDFlib+PDI 10.0.2p2 (C++/Win64); modified using iTextSharp.LGPLv2.Core 3.7.4.0 CreationDate: Wed Sep 17 01:50:29 2025 CEST ModDate: Fri Jun 5 10:27:38 2026 CEST Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 2169343 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- QWWVFE+Avenir-Black Type 1C Custom yes yes yes 825 0 WKOGKT+MyriadPro-Bold Type 1C Custom yes yes yes 26 0 LLSKSU+MyriadPro-Regular Type 1C Custom yes yes yes 27 0 MinionMathSymbols Type 1 Builtin yes no yes 826 0 KUPRAF+MyriadPro-BoldIt Type 1C Custom yes yes yes 28 0 JIZEIP+MinionMath-Regular Type 1C Custom yes yes yes 29 0 CCQTTO+MinionPro-Regular Type 1C Custom yes yes yes 30 0 Courier Type 1 WinAnsi no no no 1 0 BXNCMZ+MinionPro-It Type 1C Custom yes yes yes 59 0 HLJIGM+MyriadPro-It Type 1C Custom yes yes yes 71 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-06-06 04:32:47 CEST RepresentationInformation: 328738.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-06-05 10:32:29 CEST Size: 2169343 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Tagged PDF PDFMetadata: Objects: 872 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: true NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Language: en Outlines: Item: Title: Lebrikizumab Improved Itch Symptoms and Reduced Itch Interference on Sleep over 52 Weeks in Patients with Moderate-to-Sever ... Destination: titlink1 Children: Item: Title: Introduction Destination: flink1 Item: Title: Methods Destination: flink2 Children: Item: Title: Statistical Analysis Destination: slink1 Item: Title: Results Destination: flink3 Children: Item: Title: Patients Who Achieved Protocol-Defined Response Criteria Destination: slink2 Item: Title: Patients Who Did Not Achieve Protocol-Defined Response Criteria Destination: slink3 Item: Title: Discussion Destination: flink4 Item: Title: Conclusions Destination: flink5 Item: Title: Key Message Destination: flink6 Item: Title: Acknowledgments Destination: flink7 Item: Title: Statement of Ethics Destination: flink8 Item: Title: Conflict of Interest Statement Destination: flink9 Item: Title: Funding Sources Destination: flink10 Item: Title: Author Contributions Destination: flink11 Item: Title: Data Availability Statement Destination: flink12 Item: Title: References Destination: rlink1 Info: Title: drm_547142_Lebrikizumab Improved Itch Symptoms and 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