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Cytometry and confocal microscopy Destination: mk:H2_5 Item: Title: 2.6 Bioaccumulation and metabolization of PHE: cell and medium extraction and determination by GC-MS Destination: mk:H2_6 Item: Title: 2.7 Zebrafish husbandry and breeding Destination: mk:H2_7 Item: Title: 2.8 PHE and PHE + PS-NPs toxicity in Zebrafish larvae Destination: mk:H2_8 Item: Title: 2.9 Uptake of PS-NPs in presence of PHE in Zebrafish Larvae Destination: mk:H2_9 Item: Title: 2.10 Bioaccumulation of PHE in presence of PS-NPs in Zebrafish Larvae Destination: mk:H2_10 Item: Title: 2.11 Statistical analysis Destination: mk:H2_11 Item: Title: 3 Results Destination: mk:H1_3 Children: Item: Title: 3.1 PHE toxicity in the presence of PS-NPs in ZFL and RTgutGC cells Destination: mk:H2_12 Item: Title: 3.2 Uptake of PS-NPs in ZFL and RTgutGC cells in the presence of PHE Destination: mk:H2_13 Item: Title: 3.3 Bioaccumulation and metabolization of PHE in ZFL and RTgutGC cells in presence of PS-NPs Destination: mk:H2_14 Item: Title: 3.4 PHE and PHE + PS-NPs toxicity in zebrafish larvae Destination: mk:H2_15 Item: Title: 3.5 Uptake of PS-NPs by zebrafish larvae in the presence of PHE Destination: mk:H2_16 Item: Title: 3.6 Uptake of PHE in zebrafish Larvae in presence of PS-NPs Destination: mk:H2_17 Item: Title: 4 Discussion Destination: mk:H1_4 Children: Item: Title: 4.1 Cell and tissue type-dependent effects on PS-NPs and PHE co-exposure Destination: mk:H2_18 Item: Title: 4.2 Antagonistic and synergistic effects between PHE and PS-NPs in zebrafish larvae Destination: mk:H2_19 Item: Title: 5 Conclusions Destination: mk:H1_5 Item: Title: Environmental implications Destination: mk:H1_6 Item: Title: CRediT authorship contribution statement Destination: mk:H1_7 Item: Title: Declaration of Competing Interest Destination: mk:HH1_5 Item: Title: Acknowledgments Destination: mk:HH1_6 Item: Title: Appendix A Supporting information Destination: mk:H1_8 Item: Title: Data availability Destination: datalink7 Item: Title: References Destination: mk:HH2_1 Info: Title: Complex combined effects of polystyrene nanoplastics and phenanthrene in aquatic models Author: Paloma De Oro-Carretero Subject: Journal of Hazardous Materials, 496 (2025) 139356. doi:10.1016/j.jhazmat.2025.139356 Keywords: Nanoplastics,Phenanthrene,Co-exposure,Zebrafish larvae,Cells,Effects Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Fri Sep 05 09:18:23 CEST 2025 ModDate: Fri Sep 05 11:46:36 CEST 2025 ID: 0xac78a5e2bdaa67e2dbd59778671ee095, 0x120234e07d3120f51ce6c08289d9cfb1 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 248 ImageHeight: 271 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 236 ImageHeight: 298 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg 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Journal of Hazardous Materials, 496 (2025) 139356. doi:10.1016/j.jhazmat.2025.139356 Nanoplastics Phenanthrene Co-exposure Zebrafish larvae Cells Effects Complex combined effects of polystyrene nanoplastics and phenanthrene in aquatic models Paloma De Oro-Carretero Marlid Garcia-Ordoñez Nerea Roher Jon Sanz-Landaluze VoR 5th September 2025 Acrobat Distiller 8.1.0 (Windows) Nanoplastics,Phenanthrene,Co-exposure,Zebrafish larvae,Cells,Effects 5th September 2025 sciencedirect.com elsevier.com true 2010-04-23 10.1016/j.jhazmat.2025.139356 noindex journal © 2025 The Authors. 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