5b41689a475ee719c71a9e8fbcc81d81  HorRes_a2025v12n8p138.pdf
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67f51ca10b940e16422a7c602da640859d74aa71089c9ab3cb74ac9b29ab46e8  HorRes_a2025v12n8p138.pdf

Title:           CmFUL1 was potentially involved in fruit elongation in melon
Subject:          DOI: 10.1093/hr/uhaf138, Horticulture Research, 12, 00, 1 8 2025. Abstract: Melon (Cucumis melo L.) is a fruit crop in the world; fruit size and fruit shape are major traits for melon quality. Fruit length is a crucial indicator affecting fruit size and shape, but few genes regulating this trait have been identified. Here, we identified the transcription factor CmFUL1 (FRUITFULL) as a candidate for regulating fruit length using genome-wide association analysis (GWAS) and phylogenetic analysis. CmFUL1 is mainly expressed during flower and ovary development by tissue-specific expression. Transcriptional analysis revealed that CmFUL1 expression levels exhibited a negative correlation with fruit length across diverse melon germplasm. Furthermore, functional characterization demonstrated that CmFUL1 acts as a negative regulator of fruit elongation, CR-Cmful1 mutants generated by CRISPR-Cas9 showing enhanced longitudinal fruits. This repressive role was evolutionarily conserved, as heterologous overexpression of CmFUL1 in tomato consistently inhibited fruit elongation. Collectively, the results suggested that CmFUL1 is a candidate gene involved in regulating fruit length in melon, and provided genetic resources for molecular breeding of melon. 
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      Title:  CmFUL1 was potentially involved in fruit elongation in melon
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        Title: Introduction
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        Title: Results
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    Title: CmFUL1 was potentially involved in fruit elongation in melon
    Author: 
    Subject:  DOI: 10.1093/hr/uhaf138, Horticulture Research, 12, 00, 1 8 2025. Abstract: Melon (Cucumis melo L.) is a fruit crop in the world; fruit size and fruit shape are major traits for melon quality. Fruit length is a crucial indicator affecting fruit size and shape, but few genes regulating this trait have been identified. Here, we identified the transcription factor CmFUL1 (FRUITFULL) as a candidate for regulating fruit length using genome-wide association analysis (GWAS) and phylogenetic analysis. CmFUL1 is mainly expressed during flower and ovary development by tissue-specific expression. Transcriptional analysis revealed that CmFUL1 expression levels exhibited a negative correlation with fruit length across diverse melon germplasm. Furthermore, functional characterization demonstrated that CmFUL1 acts as a negative regulator of fruit elongation, CR-Cmful1 mutants generated by CRISPR-Cas9 showing enhanced longitudinal fruits. This repressive role was evolutionarily conserved, as heterologous overexpression of CmFUL1 in tomato consistently inhibited fruit elongation. Collectively, the results suggested that CmFUL1 is a candidate gene involved in regulating fruit length in melon, and provided genetic resources for molecular breeding of melon. 
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<dc:creator><rdf:Seq><rdf:li>Tang Lingli</rdf:li><rdf:li>He Yuhua</rdf:li><rdf:li>Liu Bingxue</rdf:li><rdf:li>Liu Mingqian</rdf:li><rdf:li>Xu Yongyang</rdf:li><rdf:li>Zhang Jian</rdf:li><rdf:li>Kong Weihu</rdf:li><rdf:li>An Lulu</rdf:li><rdf:li>Hu Keyun</rdf:li><rdf:li>Garcia-Mas Jordi</rdf:li><rdf:li>Liu Bin</rdf:li><rdf:li>Zhao Guangwei</rdf:li></rdf:Seq></dc:creator>
<dc:description> DOI: 10.1093/hr/uhaf138, Horticulture Research, 12, 00, 1 8 2025. Abstract: Melon (Cucumis melo L.) is a fruit crop in the world; fruit size and fruit shape are major traits for melon quality. Fruit length is a crucial indicator affecting fruit size and shape, but few genes regulating this trait have been identified. Here, we identified the transcription factor CmFUL1 (FRUITFULL) as a candidate for regulating fruit length using genome-wide association analysis (GWAS) and phylogenetic analysis. CmFUL1 is mainly expressed during flower and ovary development by tissue-specific expression. Transcriptional analysis revealed that CmFUL1 expression levels exhibited a negative correlation with fruit length across diverse melon germplasm. Furthermore, functional characterization demonstrated that CmFUL1 acts as a negative regulator of fruit elongation, CR-Cmful1 mutants generated by CRISPR-Cas9 showing enhanced longitudinal fruits. This repressive role was evolutionarily conserved, as heterologous overexpression of CmFUL1 in tomato consistently inhibited fruit elongation. Collectively, the results suggested that CmFUL1 is a candidate gene involved in regulating fruit length in melon, and provided genetic resources for molecular breeding of melon. </dc:description>
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  Checksum: a25e0b9b
   Type: CRC32
  Checksum: 5b41689a475ee719c71a9e8fbcc81d81
   Type: MD5
  Checksum: 66b875bf731a3c380d86fa599b8af4884337477c
   Type: SHA-1
  Checksum: 67f51ca10b940e16422a7c602da640859d74aa71089c9ab3cb74ac9b29ab46e8
   Type: SHA-256