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Title:           The human ciliopathy protein RSG1 links the CPLANE complex to transition zone architecture
Subject:         Nature Communications, doi:10.1038/s41467-025-61005-8
Keywords:        
Author:          Neftalí Vazquez
Creator:         Springer
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     Item: 
      Title: The human ciliopathy protein RSG1 links the CPLANE complex to transition zone architecture
      Destination: title_link
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       Item: 
        Title: Results
        Destination: A1
        Children: 
         Item: 
          Title: Allelic variants of CPLANE2/RSG1 cause human ciliopathy
          Destination: B1
         Item: 
          Title: RSG1 variants disrupt RSG1 function via distinct mechanisms
          Destination: B2
         Item: 
          Title: RSG1 variants disrupt IFT-A2 recruitment to basal bodies
          Destination: B3
         Item: 
          Title: RSG1 and JBTS17 variants disrupt basal body docking
          Destination: B4
         Item: 
          Title: GTP binding is required for Rsg1 association with CPLANE
          Destination: B5
         Item: 
          Title: The GTP-dependent Rsg1 interactome
          Destination: B6
         Item: 
          Title: AlphaFold predicts direct RSG1/FAM92A interaction
          Destination: B7
         Item: 
          Title: Rsg1 recruits Fam92b specifically to docking basal bodies
          Destination: B8
         Item: 
          Title: Human RSG1 controls ciliogenesis and FAM92a recruitment
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         Item: 
          Title: CPLANE proteins recruit transition zone components
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       Item: 
        Title: Discussion
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       Item: 
        Title: Methods
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        Children: 
         Item: 
          Title: Patients
          Destination: B11
         Item: 
          Title: Patient genetic analysis
          Destination: B12
         Item: 
          Title: Xenopus embryo manipulations
          Destination: B13
         Item: 
          Title: Plasmid, mRNA, and MO microinjections
          Destination: B14
         Item: 
          Title: In vitro pull-down assay
          Destination: B15
         Item: 
          Title: Immunoblotting
          Destination: B16
         Item: 
          Title: Live imaging and image analysis for Xenopus
          Destination: B17
         Item: 
          Title: Tandem affinity purification
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         Item: 
          Title: Mass spectrometry
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         Item: 
          Title: Data analysis
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         Item: 
          Title: Protein structure modeling
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         Item: 
          Title: Human and mouse cell culture
          Destination: B22
         Item: 
          Title: Immunostaining
          Destination: B23
         Item: 
          Title: Antibodies
          Destination: B24
         Item: 
          Title: Image analysis of NPHP1 and ciliogenesis
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         Item: 
          Title: Reporting summary
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        Title: Data availability
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       Item: 
        Title: References
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        Title: Acknowledgements
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       Item: 
        Title: Author contributions
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       Item: 
        Title: Competing interests
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       Item: 
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    Author: Neftalí Vazquez
    Subject: Nature Communications, doi:10.1038/s41467-025-61005-8
    Keywords: 
    Creator: Springer
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   Type: CRC32
  Checksum: 543fe644a633f3ea0ab792294d7ff3e2
   Type: MD5
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   Type: SHA-1
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   Type: SHA-256