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Duch-Llorach Subject: Journal of Hospital Infection, 161 (2025) 1-9. doi:10.1016/j.jhin.2025.04.016 Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Tue Oct 14 23:14:02 CEST 2025 ModDate: Tue Oct 14 23:15:51 CEST 2025 ID: 0x6e9883608981d32c6b0b1eeb8e44aaa5, 0x722cfad5b326374d8064288e135e6821 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 102 ImageHeight: 102 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 296 ImageHeight: 144 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 254 ImageHeight: 278 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: NACAIO+AdvPSA35D FontSubset: true FirstChar: 46 LastChar: 119 FontDescriptor: FontName: NACAIO+AdvPSA35D Flags: Nonsymbolic FontBBox: -166, -239, 989, 791 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NACAMB+AdvPS3F4C13 FontSubset: true FirstChar: 98 LastChar: 98 FontDescriptor: FontName: NACAMB+AdvPS3F4C13 Flags: Nonsymbolic FontBBox: 0, -291, 875, 697 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NACAFJ+AdvTrebu-B FontSubset: true FirstChar: 42 LastChar: 245 FontDescriptor: FontName: NACAFJ+AdvTrebu-B Flags: Serif, Nonsymbolic FontBBox: -93, -218, 1010, 802 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: NACAMA+AdvP4C4E51 FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: NACAMA+AdvP4C4E51 Flags: Nonsymbolic FontBBox: -31, -239, 1041, 750 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NACAFK+AdvTT275472e6+20 FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: NACAFK+AdvTT275472e6+20 Flags: Symbolic FontBBox: -510, -250, 1552, 927 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: NACAPC+TimesNewRomanPS-ItalicMT FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: NACAPC+TimesNewRomanPS-ItalicMT Flags: Nonsymbolic, Italic FontBBox: -498, -307, 1333, 1023 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NACAFL+AdvP4C4E74 FontSubset: true FirstChar: 2 LastChar: 254 FontDescriptor: FontName: NACAFL+AdvP4C4E74 Flags: Symbolic FontBBox: -20, -958, 1114, 770 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: NACAPB+TimesNewRomanPSMT FontSubset: true FirstChar: 2 LastChar: 122 FontDescriptor: FontName: NACAPB+TimesNewRomanPSMT Flags: Serif, Symbolic FontBBox: -4, -216, 772, 695 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: NACAFM+AdvTrebu-R FontSubset: true FirstChar: 37 LastChar: 245 FontDescriptor: FontName: NACAFM+AdvTrebu-R Flags: Serif, Nonsymbolic FontBBox: -83, -218, 958, 833 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: NACAFN+AdvTrebu-I FontSubset: true FirstChar: 40 LastChar: 222 FontDescriptor: FontName: NACAFN+AdvTrebu-I Flags: Nonsymbolic FontBBox: -62, -218, 1020, 822 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: NACAHN+AdvTrebu-BI FontSubset: true FirstChar: 58 LastChar: 117 FontDescriptor: FontName: NACAHN+AdvTrebu-BI Flags: Nonsymbolic FontBBox: -72, -218, 1072, 833 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NACAJO+AdvPSSym FontSubset: true FirstChar: 170 LastChar: 170 FontDescriptor: FontName: NACAJO+AdvPSSym Flags: Nonsymbolic FontBBox: -177, -291, 1083, 1010 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: NACAJP+AdvPS44A44B FontSubset: true FirstChar: 100 LastChar: 101 FontDescriptor: FontName: NACAJP+AdvPS44A44B Flags: Nonsymbolic FontBBox: 0, -197, 1000, 802 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1016/j.jhin.2025.04.016 Successful implementation of a bundle to prevent increased excessive-spectrum antimicrobial use under new EUCAST susceptibility definitions: a quasi-experimental study in a tertiary hospital P. Duch-Llorach A.F. Simonetti A. Figueras-Roig A. Rivera E. Fernández de Gamarra‑Martínez L. Gras-Martin M-E. Moreno-Martinez J. Ruiz Ramos B. Zarate-Tamames F. Navarro J. López-Contreras L. Escolà-Vergé Antimicrobial stewardship Pseudomonas aeruginosa Meropenem Ceftolozane/tazobactam EUCAST breakpoints table Selective reporting Journal of Hospital Infection, 161 (2025) 1-9. doi:10.1016/j.jhin.2025.04.016 The Authors journal Journal of Hospital Infection © 2025 The Authors. 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