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Lung Cancer, 209 (2025) 108799. doi:10.1016/j.lungcan.2025.108799 NSCLC Immunotherapy Long-term outcome artificial intelligence (AI) ECOG PS 2 Real-world data Long-term outcomes from pembrolizumab monotherapy in patients with advanced NSCLC, PD-L1 expression ≥ 50 %, and poor performance status: Transformer-based AI to characterize prognostic complexity Alessio Cortellini Edoardo Garbo Giulia La Cava Fabrizio Citarella Valentina Santo Leonardo Brunetti David J Pinato Jarushka Naidoo Monica Loza Carlo Genova Scott Gettinger So Yeon Kim Ritujith Jayakrishnan Talal El Zarif Marco Russano Federica Pecci Alessandro Di Federico Michele Montrone Dwight H Owen Diego Signorelli Mingjia Li Andrea Camerini Balazs Halmos Bruno Vincenzi Giulio Metro Sai Yendamuri Francesco Grossi Eleni Josephides Bartłomiej Tomasik Raffaele Giusti Emilio Bria Martin Sebastian Maximilian Rost Fabian Acker Lorenza Landi Francesca Mazzoni Alessandro Morabito Alessandro Leonetti Luca Cantini Giannis Mountzios Sukumar Kalvapudi David O’Reilly Eleni Karapanagiotou Isabelle Monnet Javier Baena Marianna Macerelli Margarita Majem Aida Piedra Diego L Cortinovis Giuseppe Tonini Gabriele Minuti Laura Mezquita Teresa Gorria Teresa Beninato Giuseppe Lo Russo Arsela PrelaJ Andrea De Giglio Federica Biello Frank Aboubakar Nana Anne-Marie C. Dingemans Joachim GJV Aerts Roberto Ferrara Taher Abu Hejleh Kazuki Takada Abdul R Naqash Marina C Garassino Heather A. 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