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Title:           The PRC2-associated factor EPOP is required for Hox gene regulation during axial development in mice
Subject:         Developmental Biology, 527 (2025) 250-259. doi:10.1016/j.ydbio.2025.08.014
Keywords:        EPOP,Polycomb,PRC2,Hox genes,Body patterning
Author:          Ivano Mocavini
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      Title: The PRC2-associated factor EPOP is required for Hox gene regulation during axial development in mice
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        Title: 1 Introduction
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        Title: 2 Results
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          Title: 2.1 Generation of Epop knockout mice
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          Title: 2.2 EPOP-depleted blastocysts show normal cell lineage segregation and X-chromosome reactivation
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          Title: 2.3 Epop KO mice show highly penetrant homeotic transformations
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          Title: 2.4 Hox genes are misexpressed in Epop KO embryos
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        Title: 3 Discussion
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        Title: 4 Materials and methods
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          Title: 4.1 Mice
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          Title: 4.2 Zygote collection
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          Title: 4.4 Embryo transfer
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          Title: 4.5 Blastocyst differential staining and cell counting
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        Title: 5 RT-qPCR
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          Title: 5.1 Lysate preparation and genotyping
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          Title: 5.2 Mutation analysis
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          Title: 5.3 Western blot
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          Title: 5.4 Histopathological analysis
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          Title: 5.5 Skeletal stainings
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          Title: 5.6 Micro-computed tomography (Micro-CT)
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          Title: 5.7 Whole-mount in situ hybridization
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          Title: 5.8 RNA-seq
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   Type: CRC32
  Checksum: d1dc12e0182b4431b53e1a2a2a380a55
   Type: MD5
  Checksum: d3e71b9b01cfe3476f4a372fce3def06c98f206b
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  Checksum: a3b2edb4629b1414a8b88d38823fff1e99906b835b6d470ae24e73670d0367c4
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