c2388a506253d7dcb7020060f086c8c5 328043.pdf 767f4e01f23c5e1ca0b4d81fa724cf0126905b45 328043.pdf a58aacd9c7cd0c90cacfed41dc9964b5e45925640b94ee3522002632fc053514 328043.pdf Creator: Adobe InDesign 18.3 (Windows) Producer: Adobe PDF Library 17.0 CreationDate: Sun Mar 29 08:01:14 2026 CEST ModDate: Mon Mar 30 04:14:36 2026 CEST Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 1331642 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ESABZA+Wingdings-Regular CID TrueType Identity-H yes yes yes 1553 0 EFCBZA+TimesNewRomanPSMT CID TrueType Identity-H yes yes yes 1554 0 MyriadPro-SemiCn Type 1C WinAnsi yes no yes 1555 0 MyriadPro-Bold Type 1C WinAnsi yes no yes 1556 0 MyriadPro-SemiboldSemiCn Type 1C Custom yes no yes 1569 0 MyriadPro-Semibold Type 1C Custom yes no yes 1574 0 SNDHNY+TimesNewRomanPSMT TrueType WinAnsi yes yes yes 1557 0 Springnew TrueType WinAnsi yes no yes 1577 0 MyriadPro-Semibold Type 1C WinAnsi yes no yes 1649 0 MyriadPro-BoldSemiCn Type 1C Custom yes no yes 134 0 MBPFHK+TimesNewRomanPS-ItalicMT TrueType WinAnsi yes yes yes 131 0 MyriadPro-SemiCn Type 1C WinAnsi yes no yes 135 0 Springnew TrueType WinAnsi yes no yes 125 0 MyriadPro-SemiCn Type 1C WinAnsi yes no yes 143 0 Springnew TrueType WinAnsi yes no yes 138 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-05-01 04:20:53 CEST RepresentationInformation: 328043.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-04-30 09:45:28 CEST Size: 1331642 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF, Tagged PDF PDFMetadata: Objects: 1687 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: Spontaneous speech and language measures as predictive biomarkers of clinically meaningful disease progression and neurodegeneration in Huntington’s disease Children: Item: Title: Abstract Item: Title: Introduction Item: Title: Methods Children: Item: Title: Participants Item: Title: Assessments Item: Title: Neuroimaging acquisition and preprocessing Item: Title: Biosamples collection and processing Item: Title: Statistical analysis Item: Title: Results Children: Item: Title: Sample characteristics Item: Title: Cross-sectional associations in symptomatic stages (HD-ISS 2–3) Item: Title: Prediction of longitudinal significant clinical change Item: Title: Association with biomarkers of neurodegeneration Item: Title: Discussion Item: Title: References Info: Creator: Adobe InDesign 18.3 (Windows) Producer: Adobe PDF Library 17.0 CreationDate: Sun Mar 29 08:01:14 CEST 2026 ModDate: Mon Mar 30 04:14:36 CEST 2026 ID: 0x4879c4f0bb284045a52c24ed59acd70f, 0xafe93b2e7ed76641b9320b0b11113e11 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2056 ImageHeight: 1307 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2056 ImageHeight: 1058 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2056 ImageHeight: 555 BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Fonts: Type0: Font: BaseFont: ESABZA+Wingdings-Regular Encoding: Identity-H ToUnicode: true Font: BaseFont: EFCBZA+TimesNewRomanPSMT Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: MyriadPro-SemiboldSemiCn FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-SemiboldSemiCn Flags: Nonsymbolic FontBBox: -156, -250, 1115, 963 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-SemiCn FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-SemiCn Flags: Nonsymbolic FontBBox: -152, -250, 1059, 947 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MyriadPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Bold Flags: Nonsymbolic FontBBox: -163, -250, 1256, 989 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MyriadPro-Semibold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Semibold Flags: Nonsymbolic FontBBox: -161, -250, 1198, 972 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-BoldSemiCn FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-BoldSemiCn Flags: Nonsymbolic FontBBox: -159, -250, 1161, 980 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true TrueType: Font: BaseFont: MBPFHK+TimesNewRomanPS-ItalicMT FontSubset: true FirstChar: 32 LastChar: 112 FontDescriptor: FontName: MBPFHK+TimesNewRomanPS-ItalicMT Flags: Serif, Nonsymbolic, Italic FontBBox: -498, -307, 1333, 1023 FontFile2: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: SNDHNY+TimesNewRomanPSMT FontSubset: true FirstChar: 32 LastChar: 243 FontDescriptor: FontName: SNDHNY+TimesNewRomanPSMT Flags: Serif, Nonsymbolic FontBBox: -568, -307, 2046, 1040 FontFile2: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: Springnew FirstChar: 0 LastChar: 255 FontDescriptor: FontName: Springnew Flags: Serif, Nonsymbolic FontBBox: -1430, -456, 2446, 800 FontFile2: true Encoding: WinAnsiEncoding ToUnicode: true CIDFontType2: Font: BaseFont: EFCBZA+TimesNewRomanPSMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: EFCBZA+TimesNewRomanPSMT Flags: Serif, Symbolic FontBBox: -568, -307, 2046, 1040 FontFile2: true Font: BaseFont: ESABZA+Wingdings-Regular CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: ESABZA+Wingdings-Regular Flags: Symbolic FontBBox: 0, -211, 1359, 899 FontFile2: true XMP: uuid:2fa0da9a-f2de-41d7-9cbb-c3042129812f adobe:docid:indd:24bb93d9-bd1e-11dd-84db-a83b50d2aaad xmp.id:1672118d-9e34-8649-8cb8-9cdef6f63d5a proof:pdf 1 xmp.iid:6a2c1811-11ec-0140-b45a-1f38ac352f7a xmp.did:e1a49234-7259-c04b-b06b-a6de5bb2a8b2 default converted from application/x-indesign to application/pdf Adobe InDesign 18.3 (Windows) 2026-03-29T08:01:14+02:00 converted uuid:1c9d5035-cc22-404c-ab91-8fe4031cbd94 converted to PDF/A-2b pdfToolbox 2026-03-30T04:14:35+02:00 2026-03-29T08:01:14+02:00 2026-03-30T04:14:36+02:00 2026-03-30T04:14:36+02:00 Adobe InDesign 18.3 (Windows) journal 10.1007/s00702-026-03143-x 2010-04-23 true springer.com springerlink.com 2010-04-23 true 10.1007/s00702-026-03143-x springer.com springerlink.com VoR application/pdf Adobe PDF Library 17.0 False 2 B Arnau Puig-Davi http://orcid.org/0000-0001-8883-4947 Carla Franch-Marti http://orcid.org/0009-0006-2590-4307 Jesus Perez-Perez http://orcid.org/0000-0002-9835-0484 Gonzalo Olmedo-Saura http://orcid.org/0000-0003-4864-5548 Jon Rodriguez-Antiguedad http://orcid.org/0000-0002-9316-1772 Anna V zquez-Oliver http://orcid.org/0000-0002-9842-7656 I igo Ruiz-Barrio http://orcid.org/0000-0002-2015-5857 Lidia Bojtos http://orcid.org/0009-0000-3260-7876 Frederic Sampedro http://orcid.org/0000-0002-3933-1355 Javier Pagonabarraga http://orcid.org/0000-0002-3248-704X Jaime Kulisevsky http://orcid.org/0000-0003-4870-1431 Saul Martinez-Horta http://orcid.org/0000-0003-0125-7249 http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI internal A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original. DerivedFrom ResourceRef Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced. http://ns.adobe.com/xap/1.0/sType/Part# stPart Part http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/t/pg/ xmpTPg XMP Paged-Text internal XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents). PlateNames Seq Text http://ns.adobe.com/pdfx/1.3/ pdfx pdfx internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains Seq Text external Mirrors crossmark:CrossmarkDomainExclusive CrossmarkDomainExclusive Text external Mirrors crossmark:MajorVersionDate CrossmarkMajorVersionDate Text internal Mirrors crossmark:DOI doi Text http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text http://crossref.org/crossmark/1.0/ crossmark crossmark internal CrossMarkDomains CrossMarkDomains Seq Text internal CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Usual same as prism:doi DOI Text external The date when a publication was published. MajorVersionDate Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism external The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. aggregationType Text http://springernature.com/ns/xmpExtensions/2.0/ sn Springer Nature ORCID Schema external Author information: contains the name of each author and his/her ORCID (ORCiD: Open Researcher and Contributor ID). An ORCID is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors. authorInfo Bag AuthorInformation Specifies the types of author information: name and ORCID of an author. http://springernature.com/ns/xmpExtensions/2.0/authorInfo/ author AuthorInformation Gives the name of an author. name Text Gives the ORCID of an author. orcid URI http://www.niso.org/schemas/jav/1.0/ jav NISO external Values for Journal Article Version are one of the following: AO = Author’s Original SMUR = Submitted Manuscript Under Review AM = Accepted Manuscript P = Proof VoR = Version of Record CVoR = Corrected Version of Record EVoR = Enhanced Version of Record journal_article_version Closed Choice of Text Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 51, 747, 196, 737 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 143, 616, 156, 604 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 252, 616, 265, 604 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 460, 616, 473, 604 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 173, 604, 186, 591 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 318, 604, 331, 591 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 437, 604, 450, 591 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 525, 591, 537, 579 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 123, 579, 136, 566 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 224, 579, 236, 566 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 357, 579, 369, 566 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 473, 579, 486, 566 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 165, 566, 178, 554 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 513, 721, 546, 688 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 238, 680, 258, 667 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 182, 630, 202, 617 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 266, 630, 286, 617 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 107, 618, 127, 604 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 183, 618, 203, 604 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 134, 568, 154, 554 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 224, 505, 244, 492 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 97, 493, 122, 479 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 127, 493, 147, 479 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 216, 493, 236, 479 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 207, 455, 227, 442 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 232, 455, 252, 442 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 157, 405, 177, 392 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 125, 343, 145, 329 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 151, 343, 171, 329 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 234, 343, 254, 329 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 72, 330, 92, 317 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 152, 330, 172, 317 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 237, 330, 257, 317 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 247, 293, 267, 279 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 160, 280, 180, 267 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 239, 255, 259, 242 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 266, 255, 286, 242 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 51, 243, 71, 229 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 130, 243, 150, 229 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 208, 243, 228, 229 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 178, 205, 198, 192 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 266, 168, 286, 154 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 109, 155, 129, 142 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 200, 155, 220, 142 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 478, 293, 498, 279 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 388, 268, 408, 254 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 403, 230, 423, 217 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 328, 193, 348, 179 Flags: Print AppearanceDictionary: true Destination: 42 Annotation: Subtype: Link Rect: 488, 155, 508, 142 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 369, 130, 389, 117 Flags: Print AppearanceDictionary: true Destination: 42 Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 170, 718, 190, 704 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 93, 643, 113, 629 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 224, 518, 244, 504 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 98, 505, 122, 492 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 51, 455, 71, 442 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 128, 380, 148, 367 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 422, 618, 544, 604 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 605, 313, 592 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 349, 605, 354, 592 Flags: Print AppearanceDictionary: true Destination: 17 Annotation: Subtype: Link Rect: 370, 193, 375, 179 Flags: Print AppearanceDictionary: true Destination: 13 Annotation: Subtype: Link Rect: 233, 630, 253, 617 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 182, 218, 187, 204 Flags: Print AppearanceDictionary: true Destination: 13 Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 390, 168, 395, 154 Flags: Print AppearanceDictionary: true Destination: 22 Annotation: Subtype: Link Rect: 234, 155, 239, 142 Flags: Print AppearanceDictionary: true Destination: 17 Annotation: Subtype: Link Rect: 263, 155, 268, 142 Flags: Print AppearanceDictionary: true Destination: 22 Thumb: true Page: Sequence: 6 Thumb: true Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 366, 218, 386, 204 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 452, 218, 472, 204 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 306, 205, 326, 192 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 478, 168, 498, 154 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 489, 143, 509, 129 Flags: Print AppearanceDictionary: true Destination: 42 Thumb: true Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 406, 630, 426, 617 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 486, 443, 506, 429 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 306, 430, 326, 417 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 492, 343, 512, 329 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 518, 343, 538, 329 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 390, 143, 410, 129 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 489, 143, 509, 129 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 194, 630, 219, 617 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 92, 505, 112, 492 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 200, 480, 220, 467 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 146, 393, 171, 379 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 75, 330, 100, 317 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 138, 280, 158, 267 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 75, 205, 95, 192 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 170, 118, 190, 104 Flags: Print AppearanceDictionary: true Destination: 38 Annotation: Subtype: Link Rect: 263, 118, 283, 104 Flags: Print AppearanceDictionary: true Destination: 38 Thumb: true Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 432, 684, 544, 673 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 306, 674, 345, 663 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 544, 715, 544, 704 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 705, 437, 694 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 544, 675, 544, 664 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 665, 469, 654 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 387, 625, 539, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 531, 595, 544, 584 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 585, 432, 574 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 516, 555, 544, 544 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 545, 412, 534 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 380, 505, 532, 494 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 380, 475, 524, 464 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 512, 445, 544, 434 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 435, 405, 424 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 531, 405, 544, 394 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 395, 429, 384 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 381, 355, 508, 344 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 344, 315, 462, 304 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 531, 285, 544, 274 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 275, 473, 264 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 384, 235, 536, 224 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 391, 205, 544, 194 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 195, 353, 184 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 527, 175, 544, 164 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 165, 444, 154 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 544, 135, 544, 124 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 125, 442, 114 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 402, 95, 525, 84 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 202, 625, 289, 613 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 51, 615, 113, 603 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 219, 535, 289, 523 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 68, 525, 149, 513 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 85, 495, 236, 483 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 125, 465, 276, 453 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 125, 435, 254, 423 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 219, 395, 289, 383 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 68, 385, 170, 373 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 228, 355, 289, 343 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 68, 345, 177, 333 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 142, 305, 289, 293 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 68, 295, 72, 283 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 161, 245, 279, 233 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 151, 205, 289, 193 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 68, 195, 80, 183 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 215, 165, 289, 153 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 68, 155, 128, 143 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 248, 135, 289, 123 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 68, 125, 190, 113 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 128, 95, 287, 83 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 457, 735, 544, 724 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 725, 362, 714 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 376, 685, 526, 674 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 388, 645, 544, 634 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 635, 357, 624 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 391, 595, 542, 584 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 457, 565, 544, 554 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 555, 405, 544 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 421, 515, 544, 504 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 323, 505, 327, 494 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 272, 725, 289, 714 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 68, 715, 215, 704 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 228, 685, 289, 674 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 68, 675, 131, 664 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 124, 635, 289, 624 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 68, 625, 93, 614 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 194, 595, 289, 584 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 68, 585, 143, 574 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 155, 565, 271, 554 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 230, 525, 289, 514 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 68, 515, 173, 504 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 167, 485, 289, 474 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 68, 475, 112, 464 Flags: Print AppearanceDictionary: true Thumb: true Checksum: ecb7f4ae Type: CRC32 Checksum: c2388a506253d7dcb7020060f086c8c5 Type: MD5 Checksum: 767f4e01f23c5e1ca0b4d81fa724cf0126905b45 Type: SHA-1 Checksum: a58aacd9c7cd0c90cacfed41dc9964b5e45925640b94ee3522002632fc053514 Type: SHA-256