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Title:           ProAKAP4 as a predictor of semen freezability in Asturcon ponies
Subject:         Journal of Equine Veterinary Science, 162 (2026) 105912. doi:10.1016/j.jevs.2026.105912
Keywords:        ProAKAP4,AKAP4,Stallion,Spermatozoa,Motility,Bad freezer
Author:          M. Dordas-Perpinyà
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      Title: ProAKAP4 as a predictor of semen freezability in Asturcon ponies
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        Title: 1 Introduction
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        Title: 2 Materials and methods
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          Title: 2.1 Experimental group
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          Title: 2.2 Semen collection, evaluation, and cryopreservation
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          Title: 2.3 Semen motility analysis
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         Item: 
          Title: 2.4 Flow cytometry analysis in post-thawed conditions
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           Item: 
            Title: 2.4.1 Assessment of plasma membrane integrity
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            Title: 2.4.2 Assessment of acrosome integrity
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            Title: 2.4.3 Assessment of plasma membrane lipid disorder
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            Title: 2.4.4 Assessment of intracellular total ROS levels
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            Title: 2.4.5 Assessment of intracellular superoxide levels
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           Item: 
            Title: 2.4.6 Assessment of mitochondrial membrane potential
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          Title: 2.5 ProAKAP4 ELISA assays
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          Title: 2.6 Motility and proAKAP4 consumption by freezing-thawing process
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          Title: 2.7 Statistical analysis
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        Title: 3 Results
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          Title: 3.1 Motility and proAKAP4 consumption by freezing-thawing process
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          Title: 3.2 Classification of fresh and thawed Asturcon ponies’ ejaculates according to proAKAP4 concentration
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          Title: 3.3 Relationship between proAKAP4 groups and the effect of freezing Asturcon ponies’ ejaculates on sperm motility and kinem ...
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          Title: 3.4 Relationship between proAKAP4 groups and the effect of freezing Asturcon ponies’ ejaculates on plasma membrane integrity
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          Title: 3.5 Classification of Asturcon ponies’ ejaculates frozen with BotuCRIO and FAO extender according to proAKAP4 concentration
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          Title: 3.6 Relationship between proAKAP4 groups and the effect of BotuCRIO and FAO extenders for freezing of Asturcon pony’s ejacu ...
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          Title: 3.7 Relationship between proAKAP4 groups and the effect of BotuCRIO and FAO extenders for freezing of Asturcon ponies’ ejac ...
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            Title: 3.7.1 Plasma membrane integrity
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            Title: 3.7.3 Mitochondrial membrane potential (MPP)
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            Title: 3.7.4 Intracellular total reactive oxygen species (ROS) levels
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            Title: 3.7.6 Plasma membrane lipid disorder
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          Title: 3.8 Sperm freezability depending on proAKAP4 levels concentration
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        Title: 4 Discussion
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        Title: Ethical statement
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        Title: Declaration of competing interest
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        Title: Acknowledgements
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        Title: References
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   Type: CRC32
  Checksum: 5adaaf019bef6de89b63f83f1c09bdd1
   Type: MD5
  Checksum: 335470e7d38cbcae06db1c381b433dda55237e73
   Type: SHA-1
  Checksum: 2d921c2d2ac69713b49fc759d12936a35fb5d3ad5c335b87d45f3299a0a0c1b8
   Type: SHA-256