864fd327901da8fc98ef86dfa5f4ce49 International_Wound_Journal_-_2026_-_Fonseca_-_Response_to.pdf 3e5bbdee4efc8287940cb25e5f23beabf527ee9c International_Wound_Journal_-_2026_-_Fonseca_-_Response_to.pdf 610b45ba189894b132774d20bd1bf019d76a7170d65a3bc58ed760c00135d56d International_Wound_Journal_-_2026_-_Fonseca_-_Response_to.pdf Title: Response to Commentary on “Cryopreserved Total Skin Allografts From Living Donors for Complex Wound Management: A New Paradigm in Regenerative Wound Care” Subject: International Wound Journal 2026.23:e70985 Author: Marcelo Fonseca, Aldo Cañete, Luana Mandriaza, Jennifer Gómez, Jaume Masiá, Katherine Marcelain, Dino Ibaceta, Cristian Erazo, Brenda Gámez, Monserrat Rius, Florencia Disi Creator: Adobe InDesign 19.5 (Windows) Producer: Adobe PDF Library 17.0; modified using iTextSharp 5.5.13.4 ©2000-2024 iText Group NV (AGPL-version) CreationDate: Thu Jun 25 12:39:21 2026 CEST ModDate: Wed Jul 1 15:07:13 2026 CEST Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 2 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 185248 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- CXBPDK+STIXTwoText Type 1C Custom yes yes yes 15 0 MJJONQ+STIXTwoText-BoldItalic Type 1C WinAnsi yes yes yes 307 0 NKZZBO+STIXTwoText-Italic Type 1C WinAnsi yes yes yes 17 0 RTCJFG+ArialRoundedMTBold Type 1C WinAnsi yes yes no 308 0 ICYRJY+STIXTwoText-Bold Type 1C Custom yes yes yes 16 0 Times-Roman Type 1 WinAnsi no no no 5 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-07-02 04:07:18 CEST RepresentationInformation: International_Wound_Journal_-_2026_-_Fonseca_-_Response_to.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-07-01 16:27:46 CEST Size: 185248 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 2 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: true NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Language: en-US Outlines: Item: Title: Response to Commentary on “Cryopreserved Total Skin Allografts From Living Donors for Complex Wound Management: A New Paradigm in Regenerative Wound Care” Children: Item: Title: Conflicts of Interest Item: Title: Data Availability Statement Item: Title: References Filters: FilterPipeline: FlateDecode FilterPipeline: CCITTFaxDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 228 ImageHeight: 45 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 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2026-06-26trueonlinelibrary.wiley.com10.1111/iwj.70985 onlinelibrary.wiley.comtrue10.1111/iwj.709852026-06-26 VoR Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Contents: Please visit https://doi.org/10.1111/iwj.70985 for your more information Rect: 45, 25, 151, 14 Annotation: Subtype: Link Contents: Please visit https://doi.org/10.1111/iwj.70985 for your more information Rect: 181, 676, 236, 661 Annotation: Subtype: Link Contents: Department of SurgeryUniversitat Autònoma de BarcelonaBarcelonaSpain Rect: 110, 544, 118, 531 ActionDest: 39 Annotation: Subtype: Link Contents: Please visit https://orcid.org/0000-0001-6310-338X for your more information Rect: 118, 545, 131, 533 Annotation: Subtype: Link Contents: Tarapacá Skin and Tissue BankIquiqueChile Rect: 190, 544, 198, 531 ActionDest: 39 Annotation: Subtype: Link Contents: Tarapacá Skin and Tissue BankIquiqueChile Rect: 278, 544, 281, 531 ActionDest: 39 Annotation: Subtype: Link Contents: Tarapacá Skin and Tissue BankIquiqueChile Rect: 353, 544, 362, 531 ActionDest: 39 Annotation: Subtype: Link Contents: Department of SurgeryUniversitat Autònoma de BarcelonaBarcelonaSpain Rect: 423, 544, 431, 531 ActionDest: 39 Annotation: Subtype: Link Contents: Department of BasicClinical Oncology, Faculty of MedicineUniversity of ChileSantiagoChile Rect: 522, 544, 525, 531 ActionDest: 39 Annotation: Subtype: Link Contents: Tarapacá Skin and Tissue BankIquiqueChile Rect: 95, 533, 98, 520 ActionDest: 39 Annotation: Subtype: Link Contents: Faculty of Medicine Clínica AlemanaUniversidad del DesarrolloSantiagoChile Rect: 165, 533, 173, 520 ActionDest: 39 Annotation: Subtype: Link Contents: University of Chile Clinical HospitalSantiagoChile Rect: 241, 533, 244, 520 ActionDest: 39 Annotation: Subtype: Link Contents: Faculty of Medicine Clínica AlemanaUniversidad del DesarrolloSantiagoChile Rect: 315, 533, 318, 520 ActionDest: 39 Annotation: Subtype: Link Contents: Department of PathologyDr. Ernesto Torres Galdames HospitalIquiqueChile Rect: 383, 533, 387, 520 ActionDest: 39 Annotation: Subtype: Link Contents: Please visit mailto:marcelo.fonseca@autonoma.cat for your more information Rect: 166, 445, 269, 434 Annotation: Subtype: Link Contents: M.Fonseca, A.Cañete, L.Mandriaza, etal., “Cryopreserved Total Skin Allografts From Living Donors for Complex Wound Management: A New Paradigm in Regenerative Wound Care,” International Wound Journal22, no. 9 (2025): e70759, https://doi.org/10.1111/iwj.70759. Rect: 121, 359, 125, 346 ActionDest: 12 Annotation: Subtype: Link Contents: P.Rooney, M.Eagle, P.Hogg, R.Lomas, and J.Kearney, “Sterilisation of Skin Allograft With Gamma Irradiation,” Burns34, no. 5 (2008): 664 673, https://doi.org/10.1016/j.burns.2007.08.021. Rect: 197, 244, 210, 231 ActionDest: 12 Annotation: Subtype: Link Contents: P.Rooney, M.Eagle, P.Hogg, R.Lomas, and J.Kearney, “Sterilisation of Skin Allograft With Gamma Irradiation,” Burns34, no. 5 (2008): 664 673, https://doi.org/10.1016/j.burns.2007.08.021. Rect: 256, 175, 271, 162 ActionDest: 12 Annotation: Subtype: Link Contents: C.Johnston, J.Callum, J.Mohr, etal., “Disinfection of Human Skin Allografts in Tissue Banking: A Systematic Review Report,” Cell and Tissue Banking17, no. 4 (2016 December): 585 592, https://doi.org/10.1007/s1056101695692. Rect: 342, 175, 355, 162 ActionDest: 12 Annotation: Subtype: Link Contents: Please visit http://creativecommons.org/licenses/by-nc/4.0/ for your more information Rect: 202, 78, 349, 68 Annotation: Subtype: Link Rect: 519, 782, 595, 767 Page: Sequence: 2 Annotations: Annotation: Subtype: Link Contents: P. B.Medawar, “The Behaviour and Fate of Skin Autografts and Skin Homografts in Rabbits: A Report to the War Wounds Committee of the Medical Research Council,” Journal of Anatomy78, no. Pt 5 (1944): 176 199. Rect: 77, 659, 90, 647 ActionDest: 12 Annotation: Subtype: Link Contents: P.Duhamel, C.Suberbielle, P.Grimbert, etal., “AntiHLA Sensitization in Extensively Burned Patients: Extent, Associated Factors, and Reduction in Potential Access to Vascularized Composite Allotransplantation,” Transplant International28, no. 5 (2015): 582 593, https://doi.org/10.1111/tri.12540. 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