9bb51d33ccfb6cc99c7a1861757cd762 fermentation_12_00266_v2.pdf 6f9bf2abdfd854f179bc4015ff62d1083f82062f fermentation_12_00266_v2.pdf 33f24d95c1b74772ae35bcabe630efa5dc2cde2d4a4cd689d16fb4f887859a99 fermentation_12_00266_v2.pdf Title: Emerging Solid-State Fermentation in Functional Foods: Bioactive Compounds, Functionality, Sensory Quality, Microbiota Influence and Industrial Perspectives Subject: Although solid-state fermentation (SSF) has long been used in food production in various traditional contexts, it is now emerging as a particularly promising strategy for the development of functional food ingredients from plant materials and agro-industrial side streams. This review examines recent advances in the application of SSF to enhance the nutritional, functional, sensory, and technological properties of food matrices. Current evidence indicates that SSF can increase the bioactive potential of plant-based substrates by promoting the release and biotransformation of phenolic compounds, while also improving antioxidant capacity, protein digestibility, and techno-functional performance. In addition, the process may support the formation of food-relevant metabolites, including vitamins, peptides, organic acids, and other secondary compounds, while reducing selected antinutritional, allergenic, and undesirable constituents. These compositional changes are often accompanied by modifications in aroma, volatile profiles, visual attributes, and, more recently, gut microbiota-related effects. Attention is given to the use of fungal-based processes for the valorization of cereals, legumes, fruit by-products, and other underutilized substrates. The review also addresses the growing industrial interest in SSF, especially in relation to mycelium-based foods, alternative proteins, functional ingredients, and feed applications. Despite its clear potential, the broader implementation of SSF will require further research and development to support its effective translation into food applications. Keywords: filamentous fungi; agro-industrial waste; antioxidant activity; mycelium-based foods; gut microbiota Author: Jose Bueno-Mancebo, Adriana Artola, Raquel Barrena, Antoni Sánchez and Teresa Gea Creator: LaTeX with hyperref Producer: pdfTeX-1.40.25; modified using OpenPDF 1.4.2 CreationDate: Mon Jun 1 02:36:46 2026 CEST ModDate: Mon Jun 1 02:49:31 2026 CEST Custom Metadata: yes Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 21 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 5377631 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- BCLECD+URWPalladioL-Ital Type 1 Custom yes yes yes 96 0 FFOYCH+URWPalladioL-Bold Type 1 Custom yes yes yes 97 0 ULBSRI+URWPalladioL-Roma Type 1 Custom yes yes yes 98 0 IWZTOL+VnURWPalladioL Type 1 Custom yes yes yes 99 0 BBSDEQ+EURM10 Type 1 Builtin yes yes yes 184 0 QGUKZH+CMSY10 Type 1 Builtin yes yes yes 185 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-07-17 04:44:14 CEST RepresentationInformation: fermentation_12_00266_v2.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-07-16 11:37:53 CEST Size: 5377631 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 590 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Item: Title: Recent Advances in Food-Related Applications of SSF Children: Item: Title: Antioxidants and Phenolic Compounds Item: Title: Proteins and Food Functionality Item: Title: Other Bioactive Compounds Item: Title: Sensory Properties Item: Title: Effects on Gut Microbiota and Intestinal Health Item: Title: Industry Adoption of SSF Item: Title: Gaps and Critical Sight Item: Title: Conclusions and Future Perspectives Item: Title: References Info: Title: Emerging Solid-State Fermentation in Functional Foods: Bioactive Compounds, Functionality, Sensory Quality, Microbiota Influence and Industrial Perspectives Author: Jose Bueno-Mancebo, Adriana Artola, Raquel Barrena, Antoni Sánchez and Teresa Gea Subject: Although solid-state fermentation (SSF) has long been used in food production in various traditional contexts, it is now emerging as a particularly promising strategy for the development of functional food ingredients from plant materials and agro-industrial side streams. This review examines recent advances in the application of SSF to enhance the nutritional, functional, sensory, and technological properties of food matrices. Current evidence indicates that SSF can increase the bioactive potential of plant-based substrates by promoting the release and biotransformation of phenolic compounds, while also improving antioxidant capacity, protein digestibility, and techno-functional performance. In addition, the process may support the formation of food-relevant metabolites, including vitamins, peptides, organic acids, and other secondary compounds, while reducing selected antinutritional, allergenic, and undesirable constituents. These compositional changes are often accompanied by modifications in aroma, volatile profiles, visual attributes, and, more recently, gut microbiota-related effects. Attention is given to the use of fungal-based processes for the valorization of cereals, legumes, fruit by-products, and other underutilized substrates. The review also addresses the growing industrial interest in SSF, especially in relation to mycelium-based foods, alternative proteins, functional ingredients, and feed applications. Despite its clear potential, the broader implementation of SSF will require further research and development to support its effective translation into food applications. 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