80c828963a91cd104c22e3b8ca9a92d9  Early_plasma_syndecan-1_dynamics_2026.pdf
44f2fa34d340edd20c67a0922f6aa919991cd987  Early_plasma_syndecan-1_dynamics_2026.pdf
7da4c3c1016d0cfb0744997beb82565c427ba3bdb4cf7e3de0e537469190996c  Early_plasma_syndecan-1_dynamics_2026.pdf

Creator:         Adobe InDesign 18.3 (Windows)
Producer:        Adobe PDF Library 17.0; modified using iText® 5.5.13.4 ©2000-2024 iText Group NV (SPRINGER SBM; licensed version)
CreationDate:    Fri Jan  2 02:29:54 2026 CET
ModDate:         Mon Feb  2 14:30:11 2026 CET
Custom Metadata: yes
Metadata Stream: yes
Tagged:          yes
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           7
Encrypted:       no
Page size:       595.276 x 793.701 pts
Page rot:        0
File size:       1069687 bytes
Optimized:       no
PDF version:     1.4


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
MyriadPro-Regular                    Type 1C           WinAnsi          yes no  no    1253  0
MyriadPro-Light                      Type 1C           Custom           yes no  yes     55  0
MyriadPro-Bold                       Type 1C           WinAnsi          yes no  yes     33  0
MyriadPro-Regular                    Type 1C           Custom           yes no  yes     32  0
MyriadPro-It                         Type 1C           WinAnsi          yes no  yes     67  0
MyriadPro-Semibold                   Type 1C           WinAnsi          yes no  yes     35  0
MyriadPro-LightIt                    Type 1C           WinAnsi          yes no  yes   1254  0
MyriadPro-Bold                       Type 1C           WinAnsi          yes no  yes   1290  0
WarnockPro-Regular                   Type 1C           Custom           yes no  yes     34  0
MyriadPro-Regular                    Type 1C           WinAnsi          yes no  yes     38  0
MyriadPro-It                         Type 1C           WinAnsi          yes no  yes     41  0
WarnockPro-It                        Type 1C           WinAnsi          yes no  yes     54  0
MyriadPro-Regular                    Type 1C           WinAnsi          yes no  yes    222  0
MyriadPro-It                         Type 1C           WinAnsi          yes no  yes    223  0
MyriadPro-SemiboldIt                 Type 1C           WinAnsi          yes no  yes     66  0
MyriadPro-Regular                    Type 1C           WinAnsi          yes no  yes    238  0
MyriadPro-It                         Type 1C           WinAnsi          yes no  yes    234  0
KGIICT+TimesNewRomanPSMT             TrueType          WinAnsi          yes yes yes     85  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2026-07-10 04:39:15 CEST
 RepresentationInformation: Early_plasma_syndecan-1_dynamics_2026.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2026-07-09 05:33:46 CEST
  Size: 1069687
  Format: PDF
  Version: 1.4
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Tagged PDF
  PDFMetadata: 
   Objects: 1320
   FreeObjects: 1
   IncrementalUpdates: 0
   DocumentCatalog: 
    ViewerPreferences: 
     HideToolbar: false
     HideMenubar: false
     HideWindowUI: false
     FitWindow: false
     CenterWindow: false
     DisplayDocTitle: false
     NonFullScreenPageMode: UseNone
     Direction: L2R
     ViewArea: CropBox
     ViewClip: CropBox
     PrintArea: CropBox
     PageClip: CropBox
    PageLayout: SinglePage
    PageMode: UseOutlines
    Language: en-US
    Outlines: 
     Item: 
      Title: Early plasma syndecan-1 dynamics and their prognostic value in major thoracic and abdominal surgery: a prospective observational study
      Children: 
       Item: 
        Title: Abstract
       Item: 
        Title: Introduction
       Item: 
        Title: Materials and methods
        Children: 
         Item: 
          Title: Study population
         Item: 
          Title: Study procedures
         Item: 
          Title: Data collection and follow-up
         Item: 
          Title: Sample size
         Item: 
          Title: Statistical analysis
       Item: 
        Title: Results
       Item: 
        Title: Discussion
        Children: 
         Item: 
          Title: Strengths and limitations
       Item: 
        Title: Conclusion
       Item: 
        Title: References
   Info: 
    Creator: Adobe InDesign 18.3 (Windows)
    Producer: Adobe PDF Library 17.0; modified using iText® 5.5.13.4 ©2000-2024 iText Group NV (SPRINGER SBM; licensed version)
    CreationDate: Fri Jan 02 02:29:54 CET 2026
    ModDate: Mon Feb 02 14:30:11 CET 2026
   ID: 0x55d923fce312f445ae6176dc316aaba4, 0x655e4ea5df1825b8cd1d9577a2897bb5
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1489
      ImageHeight: 1477
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1100
      ImageHeight: 90
      BitsPerSample: 1
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     ImageMask: true
     Decode: 0, 1
     Name: X
   Fonts: 
    Type1: 
     Font: 
      BaseFont: MyriadPro-Regular
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-Regular
       Flags: Nonsymbolic
       FontBBox: -157, -250, 1126, 952
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MyriadPro-Bold
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-Bold
       Flags: Nonsymbolic
       FontBBox: -163, -250, 1256, 989
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: WarnockPro-Regular
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: WarnockPro-Regular
       Flags: Serif, Nonsymbolic
       FontBBox: -177, -533, 1474, 950
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MyriadPro-SemiboldIt
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-SemiboldIt
       Flags: Nonsymbolic, Italic
       FontBBox: -193, -250, 1164, 972
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: MyriadPro-It
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-It
       Flags: Nonsymbolic, Italic
       FontBBox: -185, -250, 1090, 953
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: MyriadPro-Semibold
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-Semibold
       Flags: Nonsymbolic
       FontBBox: -161, -250, 1198, 972
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: MyriadPro-Regular
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-Regular
       Flags: Nonsymbolic
       FontBBox: -157, -250, 1126, 952
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MyriadPro-LightIt
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-LightIt
       Flags: Nonsymbolic, Italic
       FontBBox: -121, -250, 1007, 863
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: WarnockPro-It
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: WarnockPro-It
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -222, -533, 1474, 950
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: MyriadPro-Light
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: MyriadPro-Light
       Flags: Nonsymbolic
       FontBBox: -49, -250, 1046, 883
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
    TrueType: 
     Font: 
      BaseFont: KGIICT+TimesNewRomanPSMT
      FontSubset: true
      FirstChar: 32
      LastChar: 32
      FontDescriptor: 
       FontName: KGIICT+TimesNewRomanPSMT
       Flags: Serif, Nonsymbolic
       FontBBox: -568, -307, 2046, 1040
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.1.0-jc003">
  <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
    <rdf:Description rdf:about=""
        xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/"
        xmlns:stRef="http://ns.adobe.com/xap/1.0/sType/ResourceRef#"
        xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#"
        xmlns:xmp="http://ns.adobe.com/xap/1.0/"
        xmlns:prism="http://prismstandard.org/namespaces/basic/2.0/"
        xmlns:crossmark="http://crossref.org/crossmark/1.0/"
        xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/"
        xmlns:jav="http://www.niso.org/schemas/jav/1.0/"
        xmlns:dc="http://purl.org/dc/elements/1.1/"
        xmlns:pdf="http://ns.adobe.com/pdf/1.3/"
        xmlns:pdfaid="http://www.aiim.org/pdfa/ns/id/"
        xmlns:pdfaExtension="http://www.aiim.org/pdfa/ns/extension/"
        xmlns:pdfaSchema="http://www.aiim.org/pdfa/ns/schema#"
        xmlns:pdfaProperty="http://www.aiim.org/pdfa/ns/property#"
        xmlns:pdfaType="http://www.aiim.org/pdfa/ns/type#"
      xmpMM:InstanceID="uuid:a7c2a649-1883-4037-a194-966ce72513ec"
      xmpMM:OriginalDocumentID="adobe:docid:indd:aca9e6a3-b7bc-11dd-9b31-8d92eded7c31"
      xmpMM:DocumentID="xmp.id:10d75004-29ce-c647-bead-4fb454d51bb9"
      xmpMM:RenditionClass="proof:pdf"
      xmpMM:VersionID="1"
      xmp:CreateDate="2026-01-02T02:29:54+01:00"
      xmp:ModifyDate="2026-02-02T14:30:11+01:00"
      xmp:MetadataDate="2026-02-02T14:30:11+01:00"
      xmp:CreatorTool="Adobe InDesign 18.3 (Windows)"
      prism:aggregationType="journal"
      crossmark:DOI="10.1186/s13741-025-00642-5"
      crossmark:MajorVersionDate="2010-04-23"
      crossmark:CrossmarkDomainExclusive="true"
      pdfx:CrossmarkMajorVersionDate="2010-04-23"
      pdfx:CrossmarkDomainExclusive="true"
      pdfx:doi="10.1186/s13741-025-00642-5"
      jav:journal_article_version="VoR"
      dc:format="application/pdf"
      pdf:Producer="Adobe PDF Library 17.0; modified using iText® 5.5.13.4 ©2000-2024 iText Group NV (SPRINGER SBM; licensed version)"
      pdf:Trapped="False"
      pdfaid:part="2"
      pdfaid:conformance="B">
      <xmpMM:DerivedFrom
        stRef:instanceID="xmp.iid:a72c4ed3-e360-c04b-bd52-87feb36fad22"
        stRef:documentID="xmp.did:ca607a5c-dd64-2746-8369-8499755450cb"
        stRef:renditionClass="default"/>
      <xmpMM:History>
        <rdf:Seq>
          <rdf:li
            stEvt:action="converted"
            stEvt:parameters="from application/x-indesign to application/pdf"
            stEvt:softwareAgent="Adobe InDesign 18.3 (Windows)"
            stEvt:when="2026-01-02T02:29:54+01:00"/>
          <rdf:li
            stEvt:action="converted"
            stEvt:instanceID="uuid:b08cd022-36ee-4fea-b085-8e760c3dd66b"
            stEvt:parameters="converted to PDF/A-2b"
            stEvt:softwareAgent="pdfToolbox"
            stEvt:when="2026-01-02T02:56:15+01:00"/>
          <rdf:li
            stEvt:action="converted"
            stEvt:instanceID="uuid:52006750-77f5-4636-9de1-5b039fdce6ff"
            stEvt:parameters="converted to PDF/A-2b"
            stEvt:softwareAgent="pdfToolbox"
            stEvt:when="2026-01-02T10:41:13+01:00"/>
        </rdf:Seq>
      </xmpMM:History>
      <crossmark:CrossMarkDomains>
        <rdf:Seq>
          <rdf:li>springer.com</rdf:li>
          <rdf:li>springerlink.com</rdf:li>
        </rdf:Seq>
      </crossmark:CrossMarkDomains>
      <pdfx:CrossMarkDomains>
        <rdf:Seq>
          <rdf:li>springer.com</rdf:li>
          <rdf:li>springerlink.com</rdf:li>
        </rdf:Seq>
      </pdfx:CrossMarkDomains>
      <pdfaExtension:schemas>
        <rdf:Bag>
          <rdf:li>
            <rdf:Description
              pdfaSchema:namespaceURI="http://ns.adobe.com/xap/1.0/mm/"
              pdfaSchema:prefix="xmpMM"
              pdfaSchema:schema="XMP Media Management Schema">
            <pdfaSchema:property>
              <rdf:Seq>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="UUID based identifier for specific incarnation of a document"
                  pdfaProperty:name="InstanceID"
                  pdfaProperty:valueType="URI"/>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="The common identifier for all versions and renditions of a document."
                  pdfaProperty:name="OriginalDocumentID"
                  pdfaProperty:valueType="URI"/>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original."
                  pdfaProperty:name="DerivedFrom"
                  pdfaProperty:valueType="ResourceRef"/>
              </rdf:Seq>
            </pdfaSchema:property>
            <pdfaSchema:valueType>
              <rdf:Seq>
                <rdf:li
                  pdfaType:description="Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced."
                  pdfaType:namespaceURI="http://ns.adobe.com/xap/1.0/sType/Part#"
                  pdfaType:prefix="stPart"
                  pdfaType:type="Part"/>
              </rdf:Seq>
            </pdfaSchema:valueType>
            </rdf:Description>
          </rdf:li>
          <rdf:li>
            <rdf:Description
              pdfaSchema:namespaceURI="http://ns.adobe.com/pdf/1.3/"
              pdfaSchema:prefix="pdf"
              pdfaSchema:schema="Adobe PDF Schema">
            <pdfaSchema:property>
              <rdf:Seq>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="A name object indicating whether the document has been modified to include trapping information"
                  pdfaProperty:name="Trapped"
                  pdfaProperty:valueType="Text"/>
              </rdf:Seq>
            </pdfaSchema:property>
            </rdf:Description>
          </rdf:li>
          <rdf:li>
            <rdf:Description
              pdfaSchema:namespaceURI="http://ns.adobe.com/xap/1.0/t/pg/"
              pdfaSchema:prefix="xmpTPg"
              pdfaSchema:schema="XMP Paged-Text">
            <pdfaSchema:property>
              <rdf:Seq>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents)."
                  pdfaProperty:name="PlateNames"
                  pdfaProperty:valueType="Seq Text"/>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="A structure containing the characteristics of a font used in a document"
                  pdfaProperty:name="Fonts"
                  pdfaProperty:valueType="Bag Font"/>
              </rdf:Seq>
            </pdfaSchema:property>
            <pdfaSchema:valueType>
              <rdf:Seq>
                <rdf:li
                  pdfaType:description="A structure containing the characteristics of a font used in a document."
                  pdfaType:namespaceURI="http://ns.adobe.com/xap/1.0/sType/Font#"
                  pdfaType:prefix="stFnt"
                  pdfaType:type="Font"/>
              </rdf:Seq>
            </pdfaSchema:valueType>
            </rdf:Description>
          </rdf:li>
          <rdf:li>
            <rdf:Description
              pdfaSchema:namespaceURI="http://ns.adobe.com/pdfx/1.3/"
              pdfaSchema:prefix="pdfx"
              pdfaSchema:schema="Adobe Document Info PDF eXtension Schema">
            <pdfaSchema:property>
              <rdf:Seq>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="ID of PDF/X standard"
                  pdfaProperty:name="GTS_PDFXVersion"
                  pdfaProperty:valueType="Text"/>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="Conformance level of PDF/X standard"
                  pdfaProperty:name="GTS_PDFXConformance"
                  pdfaProperty:valueType="Text"/>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="Company creating the PDF"
                  pdfaProperty:name="Company"
                  pdfaProperty:valueType="Text"/>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="Date when document was last modified"
                  pdfaProperty:name="SourceModified"
                  pdfaProperty:valueType="Text"/>
                <rdf:li
                  pdfaProperty:category="external"
                  pdfaProperty:description="Mirrors crossmark:CrosMarkDomains"
                  pdfaProperty:name="CrossMarkDomains"
                  pdfaProperty:valueType="Seq Text"/>
                <rdf:li
                  pdfaProperty:category="external"
                  pdfaProperty:description="Mirrors crossmark:CrossmarkDomainExclusive"
                  pdfaProperty:name="CrossmarkDomainExclusive"
                  pdfaProperty:valueType="Text"/>
                <rdf:li
                  pdfaProperty:category="external"
                  pdfaProperty:description="Mirrors crossmark:MajorVersionDate"
                  pdfaProperty:name="CrossmarkMajorVersionDate"
                  pdfaProperty:valueType="Text"/>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="Mirrors crossmark:DOI"
                  pdfaProperty:name="doi"
                  pdfaProperty:valueType="Text"/>
              </rdf:Seq>
            </pdfaSchema:property>
            </rdf:Description>
          </rdf:li>
          <rdf:li>
            <rdf:Description
              pdfaSchema:namespaceURI="http://www.aiim.org/pdfa/ns/id/"
              pdfaSchema:prefix="pdfaid"
              pdfaSchema:schema="PDF/A ID Schema">
            <pdfaSchema:property>
              <rdf:Seq>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="Part of PDF/A standard"
                  pdfaProperty:name="part"
                  pdfaProperty:valueType="Integer"/>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="Amendment of PDF/A standard"
                  pdfaProperty:name="amd"
                  pdfaProperty:valueType="Text"/>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="Conformance level of PDF/A standard"
                  pdfaProperty:name="conformance"
                  pdfaProperty:valueType="Text"/>
              </rdf:Seq>
            </pdfaSchema:property>
            </rdf:Description>
          </rdf:li>
          <rdf:li>
            <rdf:Description
              pdfaSchema:namespaceURI="http://crossref.org/crossmark/1.0/"
              pdfaSchema:prefix="crossmark"
              pdfaSchema:schema="crossmark">
            <pdfaSchema:property>
              <rdf:Seq>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="CrossMarkDomains"
                  pdfaProperty:name="CrossMarkDomains"
                  pdfaProperty:valueType="Seq Text"/>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="CrossmarkDomainExclusive"
                  pdfaProperty:name="CrossmarkDomainExclusive"
                  pdfaProperty:valueType="Text"/>
                <rdf:li
                  pdfaProperty:category="internal"
                  pdfaProperty:description="Usual same as prism:doi"
                  pdfaProperty:name="DOI"
                  pdfaProperty:valueType="Text"/>
                <rdf:li
                  pdfaProperty:category="external"
                  pdfaProperty:description="The date when a publication was published."
                  pdfaProperty:name="MajorVersionDate"
                  pdfaProperty:valueType="Text"/>
              </rdf:Seq>
            </pdfaSchema:property>
            </rdf:Description>
          </rdf:li>
          <rdf:li>
            <rdf:Description
              pdfaSchema:namespaceURI="http://prismstandard.org/namespaces/basic/2.0/"
              pdfaSchema:prefix="prism"
              pdfaSchema:schema="Prism">
            <pdfaSchema:property>
              <rdf:Seq>
                <rdf:li
                  pdfaProperty:category="external"
                  pdfaProperty:description="The aggregation type specifies the unit of aggregation for a content collection. &#xA;Comment &#xA;PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. &#xA;Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. &#xA;&#xA;"
                  pdfaProperty:name="aggregationType"
                  pdfaProperty:valueType="Text"/>
              </rdf:Seq>
            </pdfaSchema:property>
            </rdf:Description>
          </rdf:li>
          <rdf:li>
            <rdf:Description
              pdfaSchema:namespaceURI="http://www.niso.org/schemas/jav/1.0/"
              pdfaSchema:prefix="jav"
              pdfaSchema:schema="NISO">
            <pdfaSchema:property>
              <rdf:Seq>
                <rdf:li
                  pdfaProperty:category="external"
                  pdfaProperty:description="Values for Journal Article Version are one of the following:&#xA;AO = Author’s Original&#xA;SMUR = Submitted Manuscript Under Review&#xA;AM = Accepted Manuscript&#xA;P = Proof&#xA;VoR = Version of Record&#xA;CVoR = Corrected Version of Record&#xA;EVoR = Enhanced Version of Record"
                  pdfaProperty:name="journal_article_version"
                  pdfaProperty:valueType="Closed Choice of Text"/>
              </rdf:Seq>
            </pdfaSchema:property>
            </rdf:Description>
          </rdf:li>
        </rdf:Bag>
      </pdfaExtension:schemas>
    </rdf:Description>
  </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 508, 73, 538, 65
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 180, 65, 279, 57
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 56, 750, 204, 740
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 508, 682, 540, 649
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 162, 659, 167, 646
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 147, 611, 152, 598
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 158, 611, 163, 598
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 129, 539, 133, 526
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 138, 539, 143, 526
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 59, 491, 64, 478
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 70, 491, 75, 478
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 210, 443, 215, 430
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 219, 443, 224, 430
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 217, 335, 222, 322
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 228, 335, 232, 322
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 59, 239, 69, 226
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 160, 215, 165, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 170, 215, 175, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 138, 179, 148, 166
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 154, 179, 164, 166
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 363, 275, 368, 262
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 373, 275, 378, 262
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 383, 275, 393, 262
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 398, 275, 408, 262
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
     Thumb: true
    Page: 
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 96, 455, 106, 442
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 208, 383, 218, 370
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 384, 671, 393, 658
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 533, 299, 538, 286
       Flags: Print
       AppearanceDictionary: true
       Destination: 44
     Thumb: true
    Page: 
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 272, 479, 277, 466
       Flags: Print
       AppearanceDictionary: true
       Destination: 57
      Annotation: 
       Subtype: Link
       Rect: 283, 467, 288, 454
       Flags: Print
       AppearanceDictionary: true
       Destination: 57
      Annotation: 
       Subtype: Link
       Rect: 86, 335, 91, 322
       Flags: Print
       AppearanceDictionary: true
       Destination: 57
      Annotation: 
       Subtype: Link
       Rect: 77, 287, 81, 274
       Flags: Print
       AppearanceDictionary: true
       Destination: 72
     Thumb: true
    Page: 
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 212, 263, 217, 250
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 59, 215, 69, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 75, 215, 85, 202
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 307, 227, 317, 214
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 394, 155, 404, 142
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 409, 155, 419, 142
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 425, 71, 435, 58
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 440, 71, 450, 58
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
     Thumb: true
    Page: 
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 59, 671, 69, 658
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 123, 599, 132, 586
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 138, 599, 148, 586
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 153, 599, 163, 586
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 144, 467, 153, 454
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 189, 395, 198, 382
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 96, 323, 101, 310
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 107, 323, 117, 310
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 122, 323, 132, 310
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 138, 323, 148, 310
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 245, 167, 254, 154
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 485, 575, 490, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 496, 575, 506, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 511, 575, 521, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 526, 575, 536, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 304, 563, 314, 550
       Flags: Print
       AppearanceDictionary: true
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 496, 215, 535, 206
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 304, 206, 398, 197
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 284, 431, 288, 422
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 71, 422, 190, 413
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 174, 395, 272, 386
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 212, 368, 290, 359
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 71, 359, 116, 350
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 192, 341, 289, 332
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 71, 332, 75, 323
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 213, 314, 288, 305
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 71, 305, 127, 296
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 154, 269, 276, 260
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 276, 242, 288, 233
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 71, 233, 176, 224
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 201, 206, 290, 197
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 71, 197, 136, 188
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 228, 170, 287, 161
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 71, 161, 143, 152
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 132, 134, 240, 125
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 151, 107, 251, 98
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 288, 89, 288, 80
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 71, 80, 167, 71
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 439, 692, 537, 684
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 319, 683, 330, 675
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 390, 656, 502, 648
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 414, 629, 530, 621
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 377, 548, 486, 540
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 520, 521, 536, 513
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 319, 512, 457, 504
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 437, 485, 537, 477
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 319, 476, 326, 468
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 384, 440, 488, 432
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 462, 413, 537, 405
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 319, 404, 353, 396
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 497, 377, 535, 369
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 319, 368, 409, 360
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 399, 350, 525, 342
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 447, 332, 536, 324
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 319, 323, 330, 315
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 510, 305, 535, 297
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 319, 296, 390, 288
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 363, 260, 487, 252
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 487, 233, 537, 225
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 319, 224, 391, 216
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 537, 197, 537, 189
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 319, 188, 445, 180
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 411, 152, 537, 144
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
  Checksum: a8ca690f
   Type: CRC32
  Checksum: 80c828963a91cd104c22e3b8ca9a92d9
   Type: MD5
  Checksum: 44f2fa34d340edd20c67a0922f6aa919991cd987
   Type: SHA-1
  Checksum: 7da4c3c1016d0cfb0744997beb82565c427ba3bdb4cf7e3de0e537469190996c
   Type: SHA-256