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1.12.4 (2023-03-16) LastModified: 2026-09-28 15:41:01 CEST Size: 737292 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 670 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Beyond the Cumulative Antibiogram: A Weighted-Incidence Syndromic Combination Antibiogram to Guide Empirical Therapy of Bloodstream Infections in the Emergency Department Children: Item: Title: Abstract Children: Item: Title: Introduction: Item: Title: Methods: Item: Title: Results: Item: Title: Conclusions: Item: Title: Introduction Item: Title: Methods Children: Item: Title: Study Design and Setting Item: Title: Participants Item: Title: Data Collection and Variables Item: Title: Microbiology Item: Title: cAST and WISCA Construction Item: Title: Sample Size Item: Title: Statistical Methods Item: Title: Results Children: Item: Title: Study Population and Microbiology Item: Title: Cumulative Antimicrobial Susceptibility Test Item: Title: Overall WISCA Estimates Item: Title: Stratified WISCA Analyses Item: Title: Exploratory Clinical Outcome Analysis Item: Title: Discussion Item: Title: Conclusions Item: Title: Acknowledgements Item: Title: References Info: Title: Beyond the Cumulative Antibiogram: A Weighted-Incidence Syndromic Combination Antibiogram to Guide Empirical Therapy of Bloodstream Infections in the Emergency Department Author: Celso Soares Pereira Batista Subject: Infectious Diseases and Therapy, https://doi.org/10.1007/s40121-026-01437-x Keywords: Antimicrobial stewardship; Bloodstream infection; Cumulative antimicrobial susceptibility test 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antimicrobial susceptibility test report; Emergency department; Empirical antimicrobial therapy; Weighted-incidence syndromic combination antibiogram False application/pdf https://doi.org/10.1007/s40121-026-01437-x Springer Healthcare Infectious Diseases and Therapy, https://doi.org/10.1007/s40121-026-01437-x Antimicrobial stewardship Bloodstream infection Cumulative antimicrobial susceptibility test report Emergency department Empirical antimicrobial therapy Weighted-incidence syndromic combination antibiogram Beyond the Cumulative Antibiogram: A Weighted-Incidence Syndromic Combination Antibiogram to Guide Empirical Therapy of Bloodstream Infections in the Emergency Department Celso Soares Pereira Batista Laura Escolà-Vergé Ferran Navarro Alba Rivera 10.1007/s40121-026-01437-x 2010-04-23 true springer.com springerlink.com https://doi.org/10.1007/s40121-026-01437-x 10.1007/s40121-026-01437-x 2193-6382 journal Infectious Diseases and Therapy The Author(s) 2010-04-23 true 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Annotation: Subtype: Link Rect: 405, 575, 417, 563 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 56, 248, 232, 237 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 319, 411, 325, 399 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 461, 348, 466, 336 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 473, 348, 479, 336 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 436, 198, 441, 186 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 446, 198, 452, 186 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 529, 161, 535, 149 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 316, 148, 322, 136 Flags: Print AppearanceDictionary: true Destination: 178 Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 206, 690, 212, 679 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 176, 553, 182, 541 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 187, 553, 198, 541 Flags: Print AppearanceDictionary: true Destination: 219 Annotation: Subtype: Link Rect: 179, 262, 190, 250 Flags: Print AppearanceDictionary: true Destination: 219 Annotation: Subtype: Link Rect: 424, 440, 436, 429 Flags: Print AppearanceDictionary: true Destination: 219 Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 100, 614, 112, 602 Flags: Print AppearanceDictionary: true Destination: 219 Annotation: Subtype: Link Rect: 118, 614, 129, 602 Flags: Print AppearanceDictionary: true Destination: 219 Annotation: Subtype: Link Rect: 142, 370, 153, 358 Flags: Print AppearanceDictionary: true Destination: 219 Annotation: Subtype: Link Rect: 275, 336, 287, 319 Flags: Print AppearanceDictionary: true Destination: 219 Annotation: Subtype: Link Rect: 520, 616, 525, 604 Flags: Print AppearanceDictionary: true Destination: 178 Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 211, 462, 216, 450 Flags: Print AppearanceDictionary: true Destination: 59 Annotation: Subtype: Link Rect: 420, 691, 431, 679 Flags: Print AppearanceDictionary: true Destination: 219 Annotation: Subtype: Link Rect: 444, 587, 450, 575 Flags: Print AppearanceDictionary: true Destination: 73 Annotation: Subtype: Link Rect: 479, 231, 484, 219 Flags: Print AppearanceDictionary: true Destination: 100 Thumb: true Page: Sequence: 6 Thumb: true Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 331, 703, 337, 691 Flags: Print AppearanceDictionary: true Destination: 100 Annotation: Subtype: Link Rect: 466, 524, 472, 512 Flags: Print AppearanceDictionary: true Destination: 153 Annotation: Subtype: Link Rect: 493, 524, 499, 512 Flags: Print AppearanceDictionary: true Destination: 161 Annotation: Subtype: Link Rect: 385, 346, 391, 334 Flags: Print AppearanceDictionary: true Destination: 178 Thumb: true Page: Sequence: 8 Thumb: true Page: Sequence: 9 Thumb: true Page: Sequence: 10 Thumb: true Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 207, 253, 219, 241 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 114, 203, 126, 191 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 305, 266, 317, 254 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 506, 166, 518, 154 Flags: Print AppearanceDictionary: true Destination: 178 Thumb: true Page: Sequence: 12 Thumb: true Page: Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 406, 466, 412, 454 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 419, 466, 425, 454 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 432, 466, 444, 454 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 451, 466, 462, 454 Flags: Print AppearanceDictionary: true Destination: 178 Annotation: Subtype: Link Rect: 469, 466, 481, 454 Flags: Print AppearanceDictionary: true Destination: 219 Thumb: true Page: Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 94, 641, 105, 629 Flags: Print AppearanceDictionary: true Destination: 219 Thumb: true Page: Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 203, 603, 279, 591 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 56, 590, 203, 579 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 215, 483, 279, 473 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 76, 473, 189, 463 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 199, 403, 279, 393 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 76, 393, 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