57c5cbbab4cd3cfc8685e172c413afb0 REDA_a2026v61n3p70224.pdf 196d370b89597b2913aaa5364285339365e249a3 REDA_a2026v61n3p70224.pdf e2490be6bc11bd6067eb5a89144bc1550b8400352717c69af9904905c6c1fcf6 REDA_a2026v61n3p70224.pdf Title: Extracellular Vesicles From Heat‐ and Oxidative‐Stressed Granulosa Cells Improve Redox Balance and Embryo Development in Bovine Oocytes Subject: Reprod Domestic Animals 2026.61:e70224 Author: Judith Diaz-Muñoz, Yulia N. Cajas, Karina Cañón-Beltrán, Sonia Gago, Carlos Olegario Hidalgo, Manel López-Béjar, Dimitrios Rizos, Teresa Mogas Creator: Adobe InDesign 19.5 (Windows) Producer: Adobe PDF Library 17.0; modified using iText 4.2.0 by 1T3XT CreationDate: Thu Sep 17 16:01:47 2026 CEST ModDate: Mon Oct 19 15:19:48 2026 CEST Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 6 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 3390531 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- VAUMLH+STIXTwoText Type 1C Custom yes yes yes 27 0 PHOXFT+STIXTwoText-BoldItalic Type 1C WinAnsi yes yes yes 513 0 KPDTND+STIXTwoText-Italic Type 1C WinAnsi yes yes yes 29 0 VGMCLH+ArialRoundedMTBold Type 1C WinAnsi yes yes no 514 0 XBNOND+STIXTwoText-Bold Type 1C Custom yes yes yes 28 0 Times-Roman Type 1 WinAnsi no no no 5 0 VGMCLH+STIX-Regular Type 1C Custom yes yes yes 47 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2026-10-20 04:03:19 CEST RepresentationInformation: REDA_a2026v61n3p70224.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2026-10-19 15:20:54 CEST Size: 3390531 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Tagged PDF PDFMetadata: Objects: 0 FreeObjects: 2 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: true NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseNone Language: en-US Outlines: Item: Title: Extracellular Vesicles From Heat- and Oxidative-Stressed Granulosa Cells Improve Redox Balance and Embryo Development in Bovine Oocytes Children: Item: Title: ABSTRACT Item: Title: 1   |   Introduction Item: Title: 2   |   Materials and Methods Children: Item: Title: 2.1   |   Granulosa Cell Culture, Stress Induction and EVs Isolation and Characterization Item: Title: 2.2   |   In Vitro Maturation, Fertilization and Embryo Culture Item: Title: 2.3   |   Mitochondrial Activity, ROS Levels, and GSH Content Triple Staining and 3D Segmentation Item: Title: 2.4   |   Statistical Analysis Item: Title: 3   |   Results Children: Item: Title: 3.1   |   Characterization of EVs From Control and Stressed Granulosa Cells Item: Title: 3.2   |   Mitochondrial Activity, ROS Levels and GSH Content Item: Title: 3.3   |   Developmental Rates Item: Title: 4   |   Discussion Item: Title: 5   |   Conclusions Item: Title: Author Contributions Item: Title: Acknowledgements Item: Title: Funding Item: Title: Conflicts of Interest Item: Title: Data Availability Statement Item: Title: References Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode FilterPipeline: CCITTFaxDecode 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